Malaria in pregnancy: diagnosing infection and identifying fetal risk.

abstract：:Intracellular pathogens present a major health risk because of their innate ability to evade clearance. Their location within host cells and ability to react to the host environment by mutation or transcriptional changes often enables survival mechanisms to resist standard therapies. Host-directed drugs do not target ...

journal_title：Expert review of anti-infective therapy

authors： Collier MA,Gallovic MD,Peine KJ,Duong AD,Bachelder EM,Gunn JS,Schlesinger LS,Ainslie KM

更新日期：2013-11-01 00:00:00

abstract：:Nitazoxanide (Alinia, Romark Laboratories) was synthesized based on the structure of niclosamide. In vitro studies have demonstrated activity against a broad range of parasites as well as some bacteria. Three controlled trials demonstrated efficacy in cryptosporidiosis, however, the efficacy in advanced AIDS patients ...

journal_title：Expert review of anti-infective therapy

authors： White CA Jr

更新日期：2004-02-01 00:00:00

abstract：:Infections due to multidrug-resistant pathogens have an increasing impact on patients undergoing cardiac surgery. Preoperative infections, such as endocarditis, and postoperative infections, including wound and device infection, influence patient outcomes. Special interest needs to be taken in patients admitted to car...

journal_title：Expert review of anti-infective therapy

authors： Kanzler I,Weis F,Beiras-Fernandez A

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:Although evidence indicates that use of procalcitonin to guide antibiotic decisions for the treatment of acute respiratory infections (ARI) decreases antibiotic consumption and improves clinical outcomes, algorithms used within studies had differences in PCT cut-off points and frequency of testing. We ther...

journal_title：Expert review of anti-infective therapy

authors： Schuetz P,Bolliger R,Merker M,Christ-Crain M,Stolz D,Tamm M,Luyt CE,Wolff M,Schroeder S,Nobre V,Reinhart K,Branche A,Damas P,Nijsten M,Deliberato RO,Verduri A,Beghé B,Cao B,Shehabi Y,Jensen JS,Beishuizen A,de Jo

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) infection is associated with intensive care admissions, morbidity, and mortality. Our study aimed to determine the incidence, risk factors, and patient outcomes of CRE in the ICU units. METHODS:This was a retrospective matched case-control study of patients admi...

journal_title：Expert review of anti-infective therapy

authors： Aleidan FAS,Alkhelaifi H,Alsenaid A,Alromaizan H,Alsalham F,Almutairi A,Alsulaiman K,Abdel Gadir AG

更新日期：2020-09-20 00:00:00

abstract：:Over the last few decades, various extended-spectrum β-lactamases (ESBLs), which are remotely related to the classical TEM and SHV families, have emerged. Among these, CTX-M, VEB and PER variants are of particular interest due to their widespread dissemination. This article will focus on these emerging ESBLs. CTX-M wa...

journal_title：Expert review of anti-infective therapy

authors： Akinci E,Vahaboglu H

更新日期：2010-11-01 00:00:00

abstract：:Since the advent of combined antiretroviral therapy there have been reductions in mortality and morbidity from HIV, transforming the disease into a chronic medical condition where newly diagnosed individuals can expect to live a near-normal life expectancy. When choosing therapy, probably the most important considerat...

journal_title：Expert review of anti-infective therapy

authors： Scourfield A,Waters L,Nelson M

更新日期：2011-11-01 00:00:00

abstract：INTRODUCTION:Microorganisms of clinical importance frequently develop resistance to drug therapy, now a growing problem. The experience with Mycobacterium tuberculosis is a representative example of increasing multi-drug resistance. To avoid reaching a crisis in which patients could be left without adequate treatment, ...

journal_title：Expert review of anti-infective therapy

authors： Guevara Salazar JA,Morán Díaz JR,Ramírez Segura E,Trujillo Ferrara JG

更新日期：2020-10-26 00:00:00

abstract：:Invasive aspergillosis (IA) is currently an important cause of morbidity and mortality in hematopoietic stem cell transplant and solid organ transplant recipients. A high index of suspicion and careful clinical and radiological examinations are the keys to identifying infected patients early. Chest computerized axial ...

journal_title：Expert review of anti-infective therapy

authors： Salman N,Törün SH,Budan B,Somer A

更新日期：2011-03-01 00:00:00

abstract：:Hepatitis C virus infection is the leading cause of chronic liver disease in the western world. Chronic liver diseases may cause, through portal hypertension, the development of gastroesophageal varices, which can then bleed. We assess the findings of a study aimed at identifying the incidence of de novo varix develop...

journal_title：Expert review of anti-infective therapy

authors： Gentile I,Borgia G

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Tocilizumab, an inhibitor of the interleukin-6 receptor, may decrease the inflammatory response and control the symptoms of severe coronavirus disease 2019 (COVID-19), but the evidence is scarce. METHODS:This retrospective study included patients with severe COVID-19 requiring oxygen therapy who received to...

journal_title：Expert review of anti-infective therapy

authors： Tomasiewicz K,Piekarska A,Stempkowska-Rejek J,Serafińska S,Gawkowska A,Parczewski M,Niścigorska-Olsen J,Łapiński TW,Zarębska-Michaluk D,Kowalska JD,Horban A,Flisiak R

更新日期：2021-01-01 00:00:00

abstract：:TB is typically caused by Mycobacterium tuberculosis, a symbiotic bacterium present in one-third of the world's population. There any many factors triggering overt clinical disease in a small proportion of humans. In our view the major role in the process is played by the host's immune response, especially self-direct...

journal_title：Expert review of anti-infective therapy

authors： Bourinbaiar AS,Mezentseva MV,Butov DA,Nyasulu PS,Efremenko YV,Jirathitikal V,Mishchenko VV,Kutsyna GA

更新日期：2012-03-01 00:00:00

abstract：:Pre- and neonatal screening for congenital toxoplasmosis rests upon the assumption that treatment is beneficial on either acute symptoms or in preventing later reactivation. Postpartum treatment of congenital toxoplasmosis with sulfadiazine and pyrimethamine has remained almost unchanged for 50 years. More recently, s...

journal_title：Expert review of anti-infective therapy

authors： Petersen E,Schmidt DR

更新日期：2003-06-01 00:00:00

abstract：:A defective mucociliary clearance facilitates colonization with bacteria and fungal spores in cystic fibrosis patients. Yeasts and molds are cultured from the cystic fibrosis respiratory tract and often their clinical relevance is unknown. Candida spp. are the most commonly isolated yeasts, whereas Aspergillus spp., S...

journal_title：Expert review of anti-infective therapy

authors： Müller FM,Seidler M

更新日期：2010-08-01 00:00:00

abstract：INTRODUCTION:In December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak occurred and caused the coronavirus disease of 2019 (COVID-19), which affected ~ 190 countries. The World Health Organization (WHO) has declared COVID-19 a pandemic on 11 March 2020. AREA COVERED:In the review, a com...

journal_title：Expert review of anti-infective therapy

authors： Bhagat S,Yadav N,Shah J,Dave H,Swaraj S,Tripathi S,Singh S

更新日期：2020-12-07 00:00:00

abstract：:Lopinavir is a protease inhibitor (PI) for the treatment of HIV infection that was specifically designed to overcome the shortcomings of earlier agents in this class. It is the only PI coformulated with ritonavir, whose pharmacological boosting effect results in a highly potent, well-tolerated, clinically effective an...

journal_title：Expert review of anti-infective therapy

authors： Tan D,Walmsley S

更新日期：2007-02-01 00:00:00

abstract：:Tuberculosis continues to be a major global health problem. Lack of accurate, rapid and cost-effective diagnostic tests poses a huge obstacle to global TB control. While several new diagnostic tools are being developed and evaluated for TB, it is important that new tools are introduced for widespread use only after ca...

journal_title：Expert review of anti-infective therapy

authors： Sohn H,Minion J,Albert H,Dheda K,Pai M

更新日期：2009-08-01 00:00:00

abstract：:Nosocomial infections are the most frequent complications observed in surgical patients. In colorectal surgery, the opening of the viscera causes the dissemination into the operative field of microorganisms originating from endogenous sources, increasing the chance of developing postoperative complications. It is repo...

journal_title：Expert review of anti-infective therapy

authors： Rovera F,Diurni M,Dionigi G,Boni L,Ferrari A,Carcano G,Dionigi R

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:The coronavirus disease 2019 (COVID-19) pandemic has affected almost 2.5 million people worldwide with almost 170,000 deaths reported to date. So far, there is scarce evidence for the current treatment options available for COVID-19. Vitamin C has previously been used for treatment of severe sepsis and septi...

journal_title：Expert review of anti-infective therapy

authors： Hiedra R,Lo KB,Elbashabsheh M,Gul F,Wright RM,Albano J,Azmaiparashvili Z,Patarroyo Aponte G

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:COVID-19 disease progresses through a number of distinct phases. The management of each phase is unique and specific. The pulmonary phase of COVID-19 is characterized by an organizing pneumonia with profound immune dysregulation, activation of clotting, and a severe microvascular injury culminating in seve...

journal_title：Expert review of anti-infective therapy

authors： Marik PE,Kory P,Varon J,Iglesias J,Meduri GU

更新日期：2020-08-18 00:00:00

abstract：:Human rickettsioses caused by intracellular bacteria of the genus Rickettsia are distributed worldwide and are transmitted by arthropod vectors such as ticks, fleas, mites and lice. They have a wide range of manifestations from benign to life-threatening diseases. Mortality rates of up to 30% have been reported for so...

journal_title：Expert review of anti-infective therapy

authors： Botelho-Nevers E,Socolovschi C,Raoult D,Parola P

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Herpes zoster (HZ) or shingles occurs as a result of reactivation after a primary infection with varicella zoster virus (chickenpox). The burden of HZ in older adults in China is not well understood. We conducted a systematic literature review to understand the burden of disease related to HZ, its complica...

journal_title：Expert review of anti-infective therapy

authors： Yin D,Van Oorschot D,Jiang N,Marijam A,Saha D,Wu Z,Tang H,Diaz-Decaro J,Watson P,Xie X,Ren Y,He Y,Feng Y

更新日期：2020-09-30 00:00:00

abstract：:Knowledge of the clinical and economic impact of antimicrobial resistance is useful to influence programs and behavior in healthcare facilities, to guide policy makers and funding agencies, to define the prognosis of individual patients and to stimulate interest in developing new antimicrobial agents and therapies. Th...

journal_title：Expert review of anti-infective therapy

authors： Maragakis LL,Perencevich EN,Cosgrove SE

更新日期：2008-10-01 00:00:00

abstract：:During the 2010 HIV Diagnostics Conference, which took place in Orlando (FL, USA) between 24 and 26 March 2010, salient new data related to three aspects of HIV testing (rapid point-of-care testing, laboratory assays and new technologies) were presented and discussed. A conundrum central to HIV diagnostics in the USA ...

journal_title：Expert review of anti-infective therapy

authors： Pandori MW,Branson BM

更新日期：2010-06-01 00:00:00

abstract：INTRODUCTION:Listeriosis is an uncommon foodborne infection that may cause moderate maternal illness, but can be extremely serious for the fetus and the newborn. Several guidelines have been elaborated in order to help clinicians on the care of pregnant women with known or suspected exposure to Listeria monocytogenes. ...

journal_title：Expert review of anti-infective therapy

authors： Pucci L,Massacesi M,Liuzzi G

更新日期：2018-01-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP) remains a major burden to the healthcare system and intubated patients in intensive care units. In fact, VAP is responsible for at least 50% of prescribed antibiotics to patients who need mechanical ventilation. One of the factors contributing to VAP pathogenesis is believed to be...

journal_title：Expert review of anti-infective therapy

authors： Loo CY,Lee WH,Young PM,Cavaliere R,Whitchurch CB,Rohanizadeh R

更新日期：2015-03-01 00:00:00

abstract：:Objectives: Extent of post-treatment fibrosis change in patients with different stages of fibrosis not fully known. We aimed to study changes in liver fibrosis in chronic hepatitis C patients who were treated with pegylated interferon/ribavirin (PEG/RBV) or direct acting antivirals (DAAs). Methods: Retrospective evalu...

journal_title：Expert review of anti-infective therapy

authors： Abdelsameea E,Alsebaey A,Abdel-Samiee M,Abdel-Razek W,Salama M,Waked I

更新日期：2020-12-29 00:00:00

abstract：:This report, completed in November 2003, is intended to serve as a resource for physicians, public health officials and organizations involved in the evaluation and treatment of Lyme disease. ...

journal_title：Expert review of anti-infective therapy

authors： Cameron D,Gaito A,Harris N,Bach G,Bellovin S,Bock K,Bock S,Burrascano J,Dickey C,Horowitz R,Phillips S,Meer-Scherrer L,Raxlen B,Sherr V,Smith H,Smith P,Stricker R,ILADS Working Group.

更新日期：2004-01-01 00:00:00

abstract：:Chagas disease affects 7.7 million people and 28 million people are at risk of acquiring the disease in 15 endemic countries of Latin America. Benznidazole and nifurtimox are drugs that have been used to treat the disease. However, both drugs induce severe side effects. Treatment with benznidazole has been recommended...

journal_title：Expert review of anti-infective therapy

authors： Guedes PM,Silva GK,Gutierrez FR,Silva JS

更新日期：2011-05-01 00:00:00

abstract：:HIV-associated nephropathy (HIVAN) is the most well-known and aggressive kidney disease in HIV-1-infected patients. A variant of focal segmental glomerulosclerosis, it is characterized by the collapse of the glomerular tuft with podocyte hypertrophy/hyperplasia and foot process effacement, often with concurrent tubula...

journal_title：Expert review of anti-infective therapy

authors： Atta MG,Lucas GM,Fine DM

更新日期：2008-06-01 00:00:00