Immune approaches in tuberculosis therapy: a brief overview.

abstract：:Lymphogranuloma venereum (LGV) is a sexually transmitted infection, previously only seen in tropical regions. This changed in 2003 when the first endemically acquired LGV cases were reported in Rotterdam, the Netherlands, among predominantly HIV positive men who have sex with men (MSM). Early diagnosis is important to...

journal_title：Expert review of anti-infective therapy

authors： de Vrieze NH,de Vries HJ

更新日期：2014-06-01 00:00:00

abstract：:Telaprevir is an NS3/4A protease inhibitor that has recently received US FDA approval for the treatment of chronic HCV infection. Telaprevir is given in combination with peg-IFN-α and ribavirin and is indicated for both treatment-naive and treatment-experienced patients with genotype 1 infection. Along with the other ...

journal_title：Expert review of anti-infective therapy

authors： Muir AJ

更新日期：2011-12-01 00:00:00

abstract：:Neurocysticercosis is the most common cause of late-onset epilepsy in developing countries. The larval stage of Taenia solium is the causative agent of the disease. Recent advances in neuroimaging and serologic diagnostic techniques have led to increased recognition of its importance, but its pathogenesis is just begi...

journal_title：Expert review of anti-infective therapy

authors： Serpa JA,Yancey LS,White AC Jr

更新日期：2006-12-01 00:00:00

abstract：:The aim of this article is to review the current literature examining the use of procalcitonin-guided antibiotic therapy for management of chronic obstructive pulmonary disease (COPD) exacerbations. Procalcitonin is a serum marker that rises in response to bacterial infections, but remains low in nonbacterial infectio...

journal_title：Expert review of anti-infective therapy

authors： Tokman S,Schuetz P,Bent S

更新日期：2011-06-01 00:00:00

abstract：:In susceptible patients, invasive aspergillosis has a high incidence and a mortality of up to 80%. The diagnosis of this condition is difficult, especially in the early stages of the disease and, as a consequence, antifungal therapy, despite its expense and toxicity, is often initiated empirically. Until recently, the...

journal_title：Expert review of anti-infective therapy

authors： Doffman SR,Agrawal SG,Brown JS

更新日期：2005-08-01 00:00:00

abstract：:Human cytomegalovirus is a large DNA virus that is well-equipped to evade both innate and adaptive host immune responses and to establish lifelong latency. It is a major opportunistic pathogen in immunocompromised hosts. Following allogeneic transplantation, immune responses are often inadequate to inhibit viral react...

journal_title：Expert review of anti-infective therapy

authors： Peggs KS

更新日期：2004-08-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a common health care problem, yet many aspects of this diagnosis remain poorly understood. Its etiology is often debated and remains a significant area of research. The diagnosis of CRS is based on subjective symptoms, duration of symptoms and objective evidence of inflammation. Each of...

journal_title：Expert review of anti-infective therapy

authors： Manes RP,Batra PS

更新日期：2013-01-01 00:00:00

abstract：:Antibiotic resistance is an important factor influencing clinical outcome for patients in intensive care units. It is also associated with increased healthcare costs resulting from prolonged patient stays. The problem of antibiotic resistance is particularly acute in intensive care units because they house seriously i...

journal_title：Expert review of anti-infective therapy

authors： Johnson AP

更新日期：2003-08-01 00:00:00

abstract：INTRODUCTION:Patients with C. difficile infection (CDI) experience intestinal microflora changes that can promote the overgrowth and subsequent translocation of gut resident pathogens into the blood. Consistently, CDI due to PCR-ribotype 027 strain, severe or relapsing CDI, and treatment with high-dosage vancomycin are...

journal_title：Expert review of anti-infective therapy

authors： Falcone M,Venditti M,Sanguinetti M,Posteraro B

更新日期：2016-07-01 00:00:00

abstract：:The authors sought to study whether extended or continuous infusion of cephalosporins is associated with better clinical outcomes than short-term infusion. PubMed and Scopus databases were systematically searched. Studies reporting the clinical outcomes of patients receiving extended or continuous infusion (≥3 or 24 h...

journal_title：Expert review of anti-infective therapy

authors： Korbila IP,Tansarli GS,Karageorgopoulos DE,Vardakas KZ,Falagas ME

更新日期：2013-06-01 00:00:00

abstract：:The fixed dose combination of abacavir with lamivudine represents a new treatment option for patients infected with HIV. Fixed dose combination abacavir/lamivudine has the convenience of one pill and once-daily dosing. It achieves comparable suppression of plasma HIV RNA with the pill's individual components dosed twi...

journal_title：Expert review of anti-infective therapy

authors： Anderson AM,Bartlett JA

更新日期：2005-12-01 00:00:00

abstract：:West Nile virus (WNV) is a mosquito-borne enveloped positive-strand RNA virus that emerged in North America in 1999 in New York City. Over the past 15 years, WNV has become established throughout the USA and has spread into Canada, Mexico and the Caribbean. CDC reports indicate >41,000 clinical cases, including more t...

journal_title：Expert review of anti-infective therapy

authors： Montgomery RR,Murray KO

更新日期：2015-03-01 00:00:00

abstract：:Cationic antimicrobial peptides are a novel type of antibiotic offering much potential in the treatment of microbial-related diseases. They offer many advantages for commercial development, including a broad spectrum of action and modest size. However, despite the identification or synthetic production of thousands of...

journal_title：Expert review of anti-infective therapy

authors： Hale JD,Hancock RE

更新日期：2007-12-01 00:00:00

abstract：INTRODUCTION:Drug concentrations in tuberculosis patients on standard regimens vary widely with clinically important consequences. Areas covered: We review the available literature identifying factors correlated with pharmacokinetic variability of antituberculosis drugs. Based on population pharmacokinetic models and t...

journal_title：Expert review of anti-infective therapy

authors： McIlleron H,Chirehwa MT

更新日期：2019-01-01 00:00:00

abstract：:Identifying and managing TB in immigrating populations has been an important aspect of immigration health for over a century, with the primary aim being protecting the host population by preventing the import of communicable diseases carried by the arriving migrants. This review describes the history and development o...

journal_title：Expert review of anti-infective therapy

authors： Dara M,Gushulak BD,Posey DL,Zellweger JP,Migliori GB

更新日期：2013-02-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP) remains a major burden to the healthcare system and intubated patients in intensive care units. In fact, VAP is responsible for at least 50% of prescribed antibiotics to patients who need mechanical ventilation. One of the factors contributing to VAP pathogenesis is believed to be...

journal_title：Expert review of anti-infective therapy

authors： Loo CY,Lee WH,Young PM,Cavaliere R,Whitchurch CB,Rohanizadeh R

更新日期：2015-03-01 00:00:00

abstract：:Malaria is a curable disease, provided timely access to efficacious drugs is sought. Poor quality and, in particular, falsified antimalarial drugs harm the population of malaria endemic areas; they put lives in peril, cause economic losses to patients, families, industry, and generally undermine the trust in health sy...

journal_title：Expert review of anti-infective therapy

authors： Chaccour C,Kaur H,Del Pozo JL

更新日期：2015-04-01 00:00:00

abstract：:This report, completed in November 2003, is intended to serve as a resource for physicians, public health officials and organizations involved in the evaluation and treatment of Lyme disease. ...

journal_title：Expert review of anti-infective therapy

authors： Cameron D,Gaito A,Harris N,Bach G,Bellovin S,Bock K,Bock S,Burrascano J,Dickey C,Horowitz R,Phillips S,Meer-Scherrer L,Raxlen B,Sherr V,Smith H,Smith P,Stricker R,ILADS Working Group.

更新日期：2004-01-01 00:00:00

abstract：:Endobronchial tuberculosis is defined as tuberculous infection of the tracheobronchial tree. Although clinical features differ between various types and stages of endobronchial tuberculosis, common symptoms are cough, hemoptysis, sputum production, wheezing, chest pain, fever and dyspnea. Endobronchial tuberculosis is...

journal_title：Expert review of anti-infective therapy

authors： Rikimaru T

更新日期：2004-04-01 00:00:00

abstract：:Diarrhea is the second largest cause of mortality worldwide in children from the perinatal period to the age of 5 years. Rotavirus has been the most commonly identified viral cause of diarrhea in children. Norovirus is now recognized as the second most common viral pathogen. Adenovirus, astrovirus and sapovirus are th...

journal_title：Expert review of anti-infective therapy

authors： Anderson EJ

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:Syphilis continues to be a growing epidemic among men who have sex with men (MSM), particularly for those living with the human immunodeficiency virus (HIV). In 2016, MSM accounted for 80% of primary and secondary syphilis diagnoses in men in the United States; almost half of who were also HIV-infected. Th...

journal_title：Expert review of anti-infective therapy

authors： Refugio ON,Klausner JD

更新日期：2018-04-01 00:00:00

abstract：:Ticks can transmit a variety of viruses, bacteria or parasites that can cause serious infections or conditions in humans and animals. While tick-borne diseases are becoming an increasing and serious problem in Europe, tick-borne diseases are also responsible for major depressions in livestock production and mortality ...

journal_title：Expert review of anti-infective therapy

authors： Heyman P,Cochez C,Hofhuis A,van der Giessen J,Sprong H,Porter SR,Losson B,Saegerman C,Donoso-Mantke O,Niedrig M,Papa A

更新日期：2010-01-01 00:00:00

abstract：:Reviews the epidemiology, natural history and the current status of treatment of HIV/hepatitis B coinfection. ...

journal_title：Expert review of anti-infective therapy

authors： Benhamou Y

更新日期：2005-04-01 00:00:00

abstract：:Invasive yeast infections are a significant cause of morbidity and mortality in patients with defective immune response, such as those with cancer-related immunosuppression, organ transplantation or other immunodeficiencies, and neonates. Hospitalization in the intensive care unit may increase the risk for such infect...

journal_title：Expert review of anti-infective therapy

authors： Garbino J,Katragkou A,Roilides E

更新日期：2007-02-01 00:00:00

abstract：:Having available tools to determine the prognosis of pediatric meningococcal sepsis at admission to the Intensive Care Unit or during the course of the disease constitutes a clinical necessity. Recently, new readily measurable circulating biomarkers have been described as an additional tool for severity classification...

journal_title：Expert review of anti-infective therapy

authors： Briassoulis G,Galani A

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:Septic arthritis (SA) is an orthopedic emergency in childhood. It is uncommon in high resource settings. However, an incidence of 5-20 per 100,000 children has been reported in low-income countries. Area covered: The predictive value of serum markers is still under debate and the proposed diagnostic algori...

journal_title：Expert review of anti-infective therapy

authors： Chiappini E,Mastrolia MV,Galli L,De Martino M,Lazzeri S

更新日期：2016-11-01 00:00:00

abstract：:Pre- and neonatal screening for congenital toxoplasmosis rests upon the assumption that treatment is beneficial on either acute symptoms or in preventing later reactivation. Postpartum treatment of congenital toxoplasmosis with sulfadiazine and pyrimethamine has remained almost unchanged for 50 years. More recently, s...

journal_title：Expert review of anti-infective therapy

authors： Petersen E,Schmidt DR

更新日期：2003-06-01 00:00:00

abstract：INTRODUCTION:Influenza-Like Illness is a leading cause of hospitalization in children. Disease burden due to influenza and other respiratory viral infections is reported on a population level, but clinical scores measuring individual changes in disease severity are urgently needed. Areas covered: We present a composite...

journal_title：Expert review of anti-infective therapy

authors： Rath B,Conrad T,Myles P,Alchikh M,Ma X,Hoppe C,Tief F,Chen X,Obermeier P,Kisler B,Schweiger B

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) infection is associated with intensive care admissions, morbidity, and mortality. Our study aimed to determine the incidence, risk factors, and patient outcomes of CRE in the ICU units. METHODS:This was a retrospective matched case-control study of patients admi...

journal_title：Expert review of anti-infective therapy

authors： Aleidan FAS,Alkhelaifi H,Alsenaid A,Alromaizan H,Alsalham F,Almutairi A,Alsulaiman K,Abdel Gadir AG

更新日期：2020-09-20 00:00:00

abstract：:Tuberculosis continues to be a major health problem worldwide, affecting millions of people each year. Accurate and rapid diagnosis is key to controlling the disease, yet the traditional tests for TB produce results that are either inaccurate or take too long to be definitive. A fast and reliable diagnostic method tha...

journal_title：Expert review of anti-infective therapy

authors： Al-Zamel FA

更新日期：2009-11-01 00:00:00