Syphilis incidence in men who have sex with men with human immunodeficiency virus comorbidity and the importance of integrating sexually transmitted infection prevention into HIV care.

abstract：:Invasive yeast infections are a significant cause of morbidity and mortality in patients with defective immune response, such as those with cancer-related immunosuppression, organ transplantation or other immunodeficiencies, and neonates. Hospitalization in the intensive care unit may increase the risk for such infect...

journal_title：Expert review of anti-infective therapy

authors： Garbino J,Katragkou A,Roilides E

更新日期：2007-02-01 00:00:00

abstract：:The prodrug isavuconazonium sulfate (BAL8557) is an extended-spectrum water-soluble triazole, developed for the treatment of severe invasive and life-threatening fungal diseases. Its active moiety, BAL4815, is a potent inhibitor of ergosterol biosynthesis, resulting in the disruption of fungal membrane structure and f...

journal_title：Expert review of anti-infective therapy

authors： Seyedmousavi S,Verweij PE,Mouton JW

更新日期：2015-01-01 00:00:00

abstract：:The advent of highly active antiretroviral therapy (HAART) has revolutionized the treatment of HIV. A wide variety of antiretroviral agents are now available, allowing patients and physicians a choice of effective therapy. However, drug resistance and toxicities are emerging as major treatment challenges in the HAART ...

journal_title：Expert review of anti-infective therapy

authors： Jones R,Gazzard B

更新日期：2006-04-01 00:00:00

abstract：:Sertaconazole is an imidazole-type antifungal agent that has shown considerable in vitro activity against pathogenic fungi. Various studies carried out in animal models, clinical and toxicologic trials have confirmed the value of sertaconazole in the topical treatment of superficial mycoses in dermatology and gynecolo...

journal_title：Expert review of anti-infective therapy

authors： Carrillo-Muñoz AJ,Giusiano G,Ezkurra PA,Quindós G

更新日期：2005-06-01 00:00:00

abstract：:Chronic hepatitis C is a major worldwide health problem with an estimated prevalence of 1.6-2%. The prognosis of chronic hepatitis C depends on the rate of fibrosis progression which, over a 20-30-year time span, may determine the risk of developing cirrhosis and its complications, namely hepatocellular carcinoma, liv...

journal_title：Expert review of anti-infective therapy

authors： Aghemo A,Rumi MG,Colombo M

更新日期：2009-10-01 00:00:00

abstract：:Chagas disease affects 7.7 million people and 28 million people are at risk of acquiring the disease in 15 endemic countries of Latin America. Benznidazole and nifurtimox are drugs that have been used to treat the disease. However, both drugs induce severe side effects. Treatment with benznidazole has been recommended...

journal_title：Expert review of anti-infective therapy

authors： Guedes PM,Silva GK,Gutierrez FR,Silva JS

更新日期：2011-05-01 00:00:00

abstract：:Healthy children are high transmitters of influenza and can experience poor influenza outcomes. Many questions remain about the efficacy and impect of preventive measures because most existing studies report imprecise proxies of influenza incidence, do not follow subjects throughout the entire influenza season and acr...

journal_title：Expert review of anti-infective therapy

authors： Lee BY,Shah M

更新日期：2012-10-01 00:00:00

abstract：:Endobronchial tuberculosis is defined as tuberculous infection of the tracheobronchial tree. Although clinical features differ between various types and stages of endobronchial tuberculosis, common symptoms are cough, hemoptysis, sputum production, wheezing, chest pain, fever and dyspnea. Endobronchial tuberculosis is...

journal_title：Expert review of anti-infective therapy

authors： Rikimaru T

更新日期：2004-04-01 00:00:00

abstract：:Nosocomial infections are the most frequent complications observed in surgical patients. In colorectal surgery, the opening of the viscera causes the dissemination into the operative field of microorganisms originating from endogenous sources, increasing the chance of developing postoperative complications. It is repo...

journal_title：Expert review of anti-infective therapy

authors： Rovera F,Diurni M,Dionigi G,Boni L,Ferrari A,Carcano G,Dionigi R

更新日期：2005-10-01 00:00:00

abstract：:Influenza is a ubiquitous infection with a spectrum ranging from mild to severe. The mystery regarding such variability in the clinical spectrum has not been fully unravelled, although a role for the complex interplay among virus characteristics, host immune response and environmental factors has been suggested. Antiv...

journal_title：Expert review of anti-infective therapy

authors： Virk RK,Gunalan V,Tambyah PA

更新日期：2016-01-01 00:00:00

abstract：:The well-known problems of classic treatment of the leishmaniases with pentavalent antimony (reduced efficacy), difficulties of administration and increasing frequency and severity of adverse events have stimulated the search for new drugs to treat these diseases. Other injectable, oral and topical drugs have not been...

journal_title：Expert review of anti-infective therapy

authors： Soto J,Soto P

更新日期：2006-04-01 00:00:00

abstract：:Chronic infection with the hepatitis B virus remains a serious and life-threatening disease for approximately 5% of the world's population, despite the availability of effective vaccines. Although prognoses can be improved by chemotherapy, treatment options are limited and none has been consistently successful. Interf...

journal_title：Expert review of anti-infective therapy

authors： Shaw T,Locarnini S

更新日期：2004-12-01 00:00:00

abstract：:bla NDM is a major mechanism of resistance of Gram-negative bacteria to β-lactam antibiotics including the carbapenems. bla NDM has been acquired by a large range of Gram-negative bacilli, especially by the Enterobacteriaceae and Acinetobacter spp. The combination of human factors (suboptimal antibiotic stewardship an...

journal_title：Expert review of anti-infective therapy

authors： Wailan AM,Paterson DL

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The nervous system is involved in 10-15% of patients infected with B. burgdorferi, B. afzelii and B. garinii. This review will address widespread misconceptions about the clinical phenomenology, diagnostic approach and response to treatment of neuroborreliosis. Areas covered: Improvements in diagnostic tes...

journal_title：Expert review of anti-infective therapy

authors： Halperin JJ

更新日期：2018-01-01 00:00:00

abstract：:Having available tools to determine the prognosis of pediatric meningococcal sepsis at admission to the Intensive Care Unit or during the course of the disease constitutes a clinical necessity. Recently, new readily measurable circulating biomarkers have been described as an additional tool for severity classification...

journal_title：Expert review of anti-infective therapy

authors： Briassoulis G,Galani A

更新日期：2014-09-01 00:00:00

abstract：:Since the advent of combined antiretroviral therapy there have been reductions in mortality and morbidity from HIV, transforming the disease into a chronic medical condition where newly diagnosed individuals can expect to live a near-normal life expectancy. When choosing therapy, probably the most important considerat...

journal_title：Expert review of anti-infective therapy

authors： Scourfield A,Waters L,Nelson M

更新日期：2011-11-01 00:00:00

abstract：:Although efforts to combat the HIV epidemic have focused on the perinatal reduction of HIV transmission, many children are still being infected with HIV in resource-limited settings. Access to HIV care, cotrimoxazole and antiretroviral therapy (ART) for HIV-infected children has greatly improved in recent years, and h...

journal_title：Expert review of anti-infective therapy

authors： Callens SF,McKellar MS,Colebunders R

更新日期：2008-04-01 00:00:00

abstract：INTRODUCTION:We assessed the knowledge of, attitude toward antimicrobial resistance (AMR) and practice of antimicrobial stewardship (AMS) among physicians in Nigeria to provide future guidance to the Nigerian National Action Plan for AMR. METHODS:A descriptive cross-sectional questionnaire-based study explored the phy...

journal_title：Expert review of anti-infective therapy

authors： Babatola AO,Fadare JO,Olatunya OS,Obiako R,Enwere O,Kalungia A,Ojo TO,Sunmonu TA,Desalu O,Godman B

更新日期：2020-11-02 00:00:00

abstract：INTRODUCTION:Microorganisms of clinical importance frequently develop resistance to drug therapy, now a growing problem. The experience with Mycobacterium tuberculosis is a representative example of increasing multi-drug resistance. To avoid reaching a crisis in which patients could be left without adequate treatment, ...

journal_title：Expert review of anti-infective therapy

authors： Guevara Salazar JA,Morán Díaz JR,Ramírez Segura E,Trujillo Ferrara JG

更新日期：2020-10-26 00:00:00

abstract：:Introduction: In light of the emergence of antibiotic-resistant bacteria, phage (bacteriophage) therapy has been recognized as a potential alternative or addition to antibiotics in Western medicine for use in humans.Areas covered: This review assessed the scientific literature on phage therapy published between 1 Janu...

journal_title：Expert review of anti-infective therapy

authors： Caflisch KM,Suh GA,Patel R

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The coronavirus disease 2019 (COVID-19) pandemic has affected almost 2.5 million people worldwide with almost 170,000 deaths reported to date. So far, there is scarce evidence for the current treatment options available for COVID-19. Vitamin C has previously been used for treatment of severe sepsis and septi...

journal_title：Expert review of anti-infective therapy

authors： Hiedra R,Lo KB,Elbashabsheh M,Gul F,Wright RM,Albano J,Azmaiparashvili Z,Patarroyo Aponte G

更新日期：2020-12-01 00:00:00

abstract：:The emergence of multidrug-resistant tuberculosis strains and the coinfection with HIV, together with advances in immunology, have led to renewed interest regarding ways to exploit the immune responses against Mycobacterium tuberculosis therapeutically. Here we review the fundamentals of tuberculosis therapy in view o...

journal_title：Expert review of anti-infective therapy

authors： Achkar JM,Casadevall A,Glatman-Freedman A

更新日期：2007-06-01 00:00:00

abstract：:The fixed dose combination of abacavir with lamivudine represents a new treatment option for patients infected with HIV. Fixed dose combination abacavir/lamivudine has the convenience of one pill and once-daily dosing. It achieves comparable suppression of plasma HIV RNA with the pill's individual components dosed twi...

journal_title：Expert review of anti-infective therapy

authors： Anderson AM,Bartlett JA

更新日期：2005-12-01 00:00:00

abstract：:Intracellular pathogens present a major health risk because of their innate ability to evade clearance. Their location within host cells and ability to react to the host environment by mutation or transcriptional changes often enables survival mechanisms to resist standard therapies. Host-directed drugs do not target ...

journal_title：Expert review of anti-infective therapy

authors： Collier MA,Gallovic MD,Peine KJ,Duong AD,Bachelder EM,Gunn JS,Schlesinger LS,Ainslie KM

更新日期：2013-11-01 00:00:00

abstract：:Multidrug chemotherapy for 6-9-months is one of the primary treatments in effective control of tuberculosis, although the mechanisms underlying the persistence of its etiological agent, Mycobacterium tuberculosis, against antibiotics remain unclear. Ever-mounting evidence indicates that the survival of many environmen...

journal_title：Expert review of anti-infective therapy

authors： Islam MS,Richards JP,Ojha AK

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Due to increasing intensity and complexity of therapies and longer survivorship, many patients with haematologic malignancy (HM) are at risk of invasive fungal disease (IFD). Mortality from IFD is high and treatment of an episode of IFD results in an excess length of hospital stay and costs and delays deli...

journal_title：Expert review of anti-infective therapy

authors： Douglas AP,Slavin MA

更新日期：2016-12-01 00:00:00

abstract：:Ticks can transmit a variety of viruses, bacteria or parasites that can cause serious infections or conditions in humans and animals. While tick-borne diseases are becoming an increasing and serious problem in Europe, tick-borne diseases are also responsible for major depressions in livestock production and mortality ...

journal_title：Expert review of anti-infective therapy

authors： Heyman P,Cochez C,Hofhuis A,van der Giessen J,Sprong H,Porter SR,Losson B,Saegerman C,Donoso-Mantke O,Niedrig M,Papa A

更新日期：2010-01-01 00:00:00

abstract：:Chronic hepatitis B is a worldwide health problem. Research interests have focused on the development of potent and safe antiviral agents with low resistance rates. Among these, telbivudine is an oral nucleoside analogue with specific activity against hepatitis B virus DNA polymerase. Various prospective, randomized c...

journal_title：Expert review of anti-infective therapy

authors： Lui YY,Chan HL

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:Pneumocystis pneumonia is a potentially life-threatening pulmonary infection that occurs in immunocompromised individuals and HIV-infected patients with a low CD4 cell count. Trimethoprim-sulfamethoxazole has been used as the first-line agent for treatment, but mutations within dihydropteroate synthase gen...

journal_title：Expert review of anti-infective therapy

authors： Huang YS,Yang JJ,Lee NY,Chen GJ,Ko WC,Sun HY,Hung CC

更新日期：2017-09-01 00:00:00

abstract：:HIV-associated nephropathy (HIVAN) is the most well-known and aggressive kidney disease in HIV-1-infected patients. A variant of focal segmental glomerulosclerosis, it is characterized by the collapse of the glomerular tuft with podocyte hypertrophy/hyperplasia and foot process effacement, often with concurrent tubula...

journal_title：Expert review of anti-infective therapy

authors： Atta MG,Lucas GM,Fine DM

更新日期：2008-06-01 00:00:00