Etiology, diagnosis and management of chronic rhinosinusitis.

abstract：:Introduction: Among the multidrug resistant pathogens, extended-spectrum beta-lactamase (ESBL-E) or carbapenemase-producing Enterobacteriaceae (CPE) are currently considered the main threat due to the scarcity of therapeutic options and their rapid spread around the globe. In addition to developing new antibiotics and...

journal_title：Expert review of anti-infective therapy

authors： Catho G,Huttner BD

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:International guidelines have recommended for many years to start antimicrobials as early as possible in sepsis and shock. This concept has been challenged by the controversial results of experimental studies and clinical cohorts and resulted in intense debate in the literature. This review aims to summari...

journal_title：Expert review of anti-infective therapy

authors： Dupuis C,Timsit JF

更新日期：2021-01-01 00:00:00

abstract：:Drug resistance in HIV-infected children is one of the main contributors to antiretroviral treatment (ART) failure, especially in developing countries. Sub-Saharan Africa has the largest burden of pediatric HIV infection in the world. Herein, we systematically review the current status of ART failure in HIV-infected A...

journal_title：Expert review of anti-infective therapy

authors： Jenabian MA,Costiniuk CT,Mboumba Bouassa RS,Chapdeleine Mekue Mouafo L,Brogan TV,Bélec L

更新日期：2015-01-01 00:00:00

abstract：:Chronic infection with the hepatitis B virus remains a serious and life-threatening disease for approximately 5% of the world's population, despite the availability of effective vaccines. Although prognoses can be improved by chemotherapy, treatment options are limited and none has been consistently successful. Interf...

journal_title：Expert review of anti-infective therapy

authors： Shaw T,Locarnini S

更新日期：2004-12-01 00:00:00

abstract：INTRODUCTION:Due to increasing intensity and complexity of therapies and longer survivorship, many patients with haematologic malignancy (HM) are at risk of invasive fungal disease (IFD). Mortality from IFD is high and treatment of an episode of IFD results in an excess length of hospital stay and costs and delays deli...

journal_title：Expert review of anti-infective therapy

authors： Douglas AP,Slavin MA

更新日期：2016-12-01 00:00:00

abstract：:Introduction: In light of the emergence of antibiotic-resistant bacteria, phage (bacteriophage) therapy has been recognized as a potential alternative or addition to antibiotics in Western medicine for use in humans.Areas covered: This review assessed the scientific literature on phage therapy published between 1 Janu...

journal_title：Expert review of anti-infective therapy

authors： Caflisch KM,Suh GA,Patel R

更新日期：2019-12-01 00:00:00

abstract：:Chronic hepatitis C is a major worldwide health problem with an estimated prevalence of 1.6-2%. The prognosis of chronic hepatitis C depends on the rate of fibrosis progression which, over a 20-30-year time span, may determine the risk of developing cirrhosis and its complications, namely hepatocellular carcinoma, liv...

journal_title：Expert review of anti-infective therapy

authors： Aghemo A,Rumi MG,Colombo M

更新日期：2009-10-01 00:00:00

abstract：:As a consequence of antibiotic overuse and misuse, nosocomial infections caused by multidrug-resistant bacteria represent a physician's nightmare throughout the world. No newer antimicrobials active against Pseudomonas aeruginosa, the main multidrug-resistant nosocomial pathogen, are available or under investigation. ...

journal_title：Expert review of anti-infective therapy

authors： Giamarellou H

更新日期：2006-08-01 00:00:00

abstract：:Invasive yeast infections are a significant cause of morbidity and mortality in patients with defective immune response, such as those with cancer-related immunosuppression, organ transplantation or other immunodeficiencies, and neonates. Hospitalization in the intensive care unit may increase the risk for such infect...

journal_title：Expert review of anti-infective therapy

authors： Garbino J,Katragkou A,Roilides E

更新日期：2007-02-01 00:00:00

abstract：:Sertaconazole is an imidazole-type antifungal agent that has shown considerable in vitro activity against pathogenic fungi. Various studies carried out in animal models, clinical and toxicologic trials have confirmed the value of sertaconazole in the topical treatment of superficial mycoses in dermatology and gynecolo...

journal_title：Expert review of anti-infective therapy

authors： Carrillo-Muñoz AJ,Giusiano G,Ezkurra PA,Quindós G

更新日期：2005-06-01 00:00:00

abstract：:Pertussis is a serious respiratory disease in infants that can also affect children and adults. Vaccination against pertussis was introduced in the 1950s and in the 1990s a resurgence of pertussis was observed worldwide. The aim of this work is to summarize the recent data concerning pertussis disease in different cou...

journal_title：Expert review of anti-infective therapy

authors： Falleiros Arlant LH,de Colsa A,Flores D,Brea J,Avila Aguero ML,Hozbor DF

更新日期：2014-10-01 00:00:00

abstract：:Introduction: Neonatal sepsis remains a serious and potentially fatal illness. Intrapartum antibiotic prophylaxis (IAP) prevents group B streptococcal (GBS) early-onset sepsis. The optimal duration of IAP (adequate IAP) to reduce vertical transmission of GBS has been debated. Understanding the mechanism of action of I...

journal_title：Expert review of anti-infective therapy

authors： Berardi A,Spada C,Vaccina E,Boncompagni A,Bedetti L,Lucaccioni L

更新日期：2020-01-01 00:00:00

abstract：:Five main groups of commercial assays for the multiplex detection of alpha human papillomaviruses (HPVs) are currently available. DNA-based screening assays, which test for the presence of 13-14 HPVs without determination of HPV type, have been the standard for HPV detection in the last decade. Assays that combine tes...

journal_title：Expert review of anti-infective therapy

authors： Poljak M,Kocjan BJ

更新日期：2010-10-01 00:00:00

abstract：:Lymphatic filariasis (LF) is an important public health problem endemic in 73 countries, where it is a major cause of acute and chronic morbidity and a significant impediment to socioeconomic development. It is targeted for elimination by 2020, through preventive chemotherapy using albendazole in combination with eith...

journal_title：Expert review of anti-infective therapy

authors： Rebollo MP,Bockarie MJ

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:Drug concentrations in tuberculosis patients on standard regimens vary widely with clinically important consequences. Areas covered: We review the available literature identifying factors correlated with pharmacokinetic variability of antituberculosis drugs. Based on population pharmacokinetic models and t...

journal_title：Expert review of anti-infective therapy

authors： McIlleron H,Chirehwa MT

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Listeriosis is an uncommon foodborne infection that may cause moderate maternal illness, but can be extremely serious for the fetus and the newborn. Several guidelines have been elaborated in order to help clinicians on the care of pregnant women with known or suspected exposure to Listeria monocytogenes. ...

journal_title：Expert review of anti-infective therapy

authors： Pucci L,Massacesi M,Liuzzi G

更新日期：2018-01-01 00:00:00

abstract：:Following the discovery of innate immune receptors, the topics of innate immunity and its role in defense against infective agents have recently blossomed into very active research fields, after several decades of neglect. Among innate immune cells, natural killer (NK) cells are endowed with the unique ability to reco...

journal_title：Expert review of anti-infective therapy

authors： Zucchini N,Crozat K,Baranek T,Robbins SH,Altfeld M,Dalod M

更新日期：2008-12-01 00:00:00

abstract：:The 6th World Congress of the World Society for Pediatric Infectious Diseases (WSPID), which was recently held in Buenos Aires, Argentina, between 18 and 22 November 2009, attracted 2401 attendees from 90 countries representing six continents. The WSPID, founded in 1994 by Professor Saldana Gonzalez of the Mexican Ped...

journal_title：Expert review of anti-infective therapy

authors： Falade AG

更新日期：2010-03-01 00:00:00

abstract：:The constant new emergence of life-threatening human respiratory viral pathogens presents new challenges to clinicians who are left with no available therapeutic interventions. Highly pathogenic strains of influenza A virus (IAV) share an enhanced capacity to propagate to the lower airways and paralyze alveolar macrop...

journal_title：Expert review of anti-infective therapy

authors： Coulombe F,Divangahi M

更新日期：2014-11-01 00:00:00

abstract：:Accidents or violence can result in penetrating trauma in the adult population. Contaminated penetrating foreign bodies introduced at the time of wounding cause infection, especially high velocity projectiles, which result in cavitation. Surgical debridement reduces potential infection; however, perioperative antibiot...

journal_title：Expert review of anti-infective therapy

authors： Petersen K,Waterman P

更新日期：2011-01-01 00:00:00

abstract：:Inflammation represents a complex biologic and biochemical process involving cells of the immune system and a plethora of biologic mediators in response to mechanical, chemical or infectious injuries. When mobilization of effector cells and molecules becomes excessive, the beneficial aspect of this response--to limit ...

journal_title：Expert review of anti-infective therapy

authors： Labro MT

更新日期：2005-02-01 00:00:00

abstract：:Despite increased malaria control efforts, recent reports indicate that over 1.2 million deaths due to malaria occurred in 2010. Pregnant women represent a particularly vulnerable risk group as malaria infection can lead to life-threatening disease for the mother and fetus. With 125 million women at risk of malaria in...

journal_title：Expert review of anti-infective therapy

authors： Conroy AL,McDonald CR,Kain KC

更新日期：2012-11-01 00:00:00

abstract：INTRODUCTION:Carbapenem-resistant Enterobacterales (CRE) represent a global public health problem. Precision medicine (PM) is a multicomponent medical approach that should be used to individualize the management of patients infected with CRE. AREAS COVERED:Here, we differentiate carbapenem-producing CRE (CP-CRE) from ...

journal_title：Expert review of anti-infective therapy

authors： Reyes S,Nicolau DP

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Patients with C. difficile infection (CDI) experience intestinal microflora changes that can promote the overgrowth and subsequent translocation of gut resident pathogens into the blood. Consistently, CDI due to PCR-ribotype 027 strain, severe or relapsing CDI, and treatment with high-dosage vancomycin are...

journal_title：Expert review of anti-infective therapy

authors： Falcone M,Venditti M,Sanguinetti M,Posteraro B

更新日期：2016-07-01 00:00:00

abstract：INTRODUCTION:Drug-resistant tuberculous meningitis has been reported worldwide. Isoniazid mono-resistance is the most frequent cause of drug-resistant tuberculous meningitis, a life-threatening disease. Extensive drug-resistant tuberculous meningitis has also been reported in some isolated case reports. Areas covered: ...

journal_title：Expert review of anti-infective therapy

authors： Garg RK,Rizvi I,Malhotra HS,Uniyal R,Kumar N

更新日期：2018-11-01 00:00:00

abstract：:Neurocysticercosis is the most common cause of late-onset epilepsy in developing countries. The larval stage of Taenia solium is the causative agent of the disease. Recent advances in neuroimaging and serologic diagnostic techniques have led to increased recognition of its importance, but its pathogenesis is just begi...

journal_title：Expert review of anti-infective therapy

authors： Serpa JA,Yancey LS,White AC Jr

更新日期：2006-12-01 00:00:00

abstract：:Cryptosporidiosis, the disease caused by protozoa of the genus Cryptosporidium, represents a major public health problem in both developing and developed countries. The infection can be severe and life threatening among immunocompromised individuals, particularly in AIDS patients and in those with primary immunodefici...

journal_title：Expert review of anti-infective therapy

authors： Cacciò SM,Pozio E

更新日期：2006-06-01 00:00:00

abstract：:Telaprevir is an NS3/4A protease inhibitor that has recently received US FDA approval for the treatment of chronic HCV infection. Telaprevir is given in combination with peg-IFN-α and ribavirin and is indicated for both treatment-naive and treatment-experienced patients with genotype 1 infection. Along with the other ...

journal_title：Expert review of anti-infective therapy

authors： Muir AJ

更新日期：2011-12-01 00:00:00

abstract：:A defective mucociliary clearance facilitates colonization with bacteria and fungal spores in cystic fibrosis patients. Yeasts and molds are cultured from the cystic fibrosis respiratory tract and often their clinical relevance is unknown. Candida spp. are the most commonly isolated yeasts, whereas Aspergillus spp., S...

journal_title：Expert review of anti-infective therapy

authors： Müller FM,Seidler M

更新日期：2010-08-01 00:00:00

abstract：:Nosocomial infections are the most frequent complications observed in surgical patients. In colorectal surgery, the opening of the viscera causes the dissemination into the operative field of microorganisms originating from endogenous sources, increasing the chance of developing postoperative complications. It is repo...

journal_title：Expert review of anti-infective therapy

authors： Rovera F,Diurni M,Dionigi G,Boni L,Ferrari A,Carcano G,Dionigi R

更新日期：2005-10-01 00:00:00