Optimizing the management of children with latent tuberculosis infection.

abstract：:Chronic hepatitis B is a worldwide health problem. Research interests have focused on the development of potent and safe antiviral agents with low resistance rates. Among these, telbivudine is an oral nucleoside analogue with specific activity against hepatitis B virus DNA polymerase. Various prospective, randomized c...

journal_title：Expert review of anti-infective therapy

authors： Lui YY,Chan HL

更新日期：2009-04-01 00:00:00

abstract：:Reviews the epidemiology, natural history and the current status of treatment of HIV/hepatitis B coinfection. ...

journal_title：Expert review of anti-infective therapy

authors： Benhamou Y

更新日期：2005-04-01 00:00:00

abstract：:The management of anaerobic infection needs to be prompt and appropriate in order to ensure recovery. Management includes the use of hyperbaric oxygen, surgical methods and antimicrobial therapy. Various factors, such as efficacy, bacterial antimicrobial resistance, ability to reach appropriate antimicrobial levels at...

journal_title：Expert review of anti-infective therapy

authors： Brook I

更新日期：2004-02-01 00:00:00

abstract：INTRODUCTION:The identification of factors that can predispose to the development of severe influenza is essential to enable the implementation of optimal prevention and control measures for vulnerable populations. AREAS COVERED:Unfortunately, data in the pediatric age group remain difficult to interpret. However, epi...

journal_title：Expert review of anti-infective therapy

authors： Principi N,Esposito S

更新日期：2016-10-01 00:00:00

abstract：:Having available tools to determine the prognosis of pediatric meningococcal sepsis at admission to the Intensive Care Unit or during the course of the disease constitutes a clinical necessity. Recently, new readily measurable circulating biomarkers have been described as an additional tool for severity classification...

journal_title：Expert review of anti-infective therapy

authors： Briassoulis G,Galani A

更新日期：2014-09-01 00:00:00

abstract：:A defective mucociliary clearance facilitates colonization with bacteria and fungal spores in cystic fibrosis patients. Yeasts and molds are cultured from the cystic fibrosis respiratory tract and often their clinical relevance is unknown. Candida spp. are the most commonly isolated yeasts, whereas Aspergillus spp., S...

journal_title：Expert review of anti-infective therapy

authors： Müller FM,Seidler M

更新日期：2010-08-01 00:00:00

abstract：:Following the discovery of innate immune receptors, the topics of innate immunity and its role in defense against infective agents have recently blossomed into very active research fields, after several decades of neglect. Among innate immune cells, natural killer (NK) cells are endowed with the unique ability to reco...

journal_title：Expert review of anti-infective therapy

authors： Zucchini N,Crozat K,Baranek T,Robbins SH,Altfeld M,Dalod M

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Sepsis-associated encephalopathy (SAE) and septic encephalitis (SE) are associated with increased mortality, long-term cognitive impairment, and focal neurological deficits. AREAS COVERED:The PUBMED database was searched 2016-2020. The clinical manifestation of SAE is delirium, SE additionally is characte...

journal_title：Expert review of anti-infective therapy

authors： Tauber SC,Djukic M,Gossner J,Eiffert H,Brück W,Nau R

更新日期：2020-09-14 00:00:00

abstract：:HIV-associated nephropathy (HIVAN) is the most well-known and aggressive kidney disease in HIV-1-infected patients. A variant of focal segmental glomerulosclerosis, it is characterized by the collapse of the glomerular tuft with podocyte hypertrophy/hyperplasia and foot process effacement, often with concurrent tubula...

journal_title：Expert review of anti-infective therapy

authors： Atta MG,Lucas GM,Fine DM

更新日期：2008-06-01 00:00:00

abstract：INTRODUCTION:Latent tuberculosis infection (LTBI) accounts for almost a quarter of the world population, and, in 5-10% of the subjects with impaired immune-response against M. tuberculosis growth, it may progress to active tuberculosis (TB). In this review, we focus on the need to propose a screening for LTBI including...

journal_title：Expert review of anti-infective therapy

authors： Goletti D,Petrone L,Ippolito G,Niccoli L,Nannini C,Cantini F

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The coronavirus disease 2019 (COVID-19) pandemic has affected almost 2.5 million people worldwide with almost 170,000 deaths reported to date. So far, there is scarce evidence for the current treatment options available for COVID-19. Vitamin C has previously been used for treatment of severe sepsis and septi...

journal_title：Expert review of anti-infective therapy

authors： Hiedra R,Lo KB,Elbashabsheh M,Gul F,Wright RM,Albano J,Azmaiparashvili Z,Patarroyo Aponte G

更新日期：2020-12-01 00:00:00

abstract：:The emergence of multidrug-resistant tuberculosis strains and the coinfection with HIV, together with advances in immunology, have led to renewed interest regarding ways to exploit the immune responses against Mycobacterium tuberculosis therapeutically. Here we review the fundamentals of tuberculosis therapy in view o...

journal_title：Expert review of anti-infective therapy

authors： Achkar JM,Casadevall A,Glatman-Freedman A

更新日期：2007-06-01 00:00:00

abstract：:Pertussis is a serious respiratory disease in infants that can also affect children and adults. Vaccination against pertussis was introduced in the 1950s and in the 1990s a resurgence of pertussis was observed worldwide. The aim of this work is to summarize the recent data concerning pertussis disease in different cou...

journal_title：Expert review of anti-infective therapy

authors： Falleiros Arlant LH,de Colsa A,Flores D,Brea J,Avila Aguero ML,Hozbor DF

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) infection is associated with intensive care admissions, morbidity, and mortality. Our study aimed to determine the incidence, risk factors, and patient outcomes of CRE in the ICU units. METHODS:This was a retrospective matched case-control study of patients admi...

journal_title：Expert review of anti-infective therapy

authors： Aleidan FAS,Alkhelaifi H,Alsenaid A,Alromaizan H,Alsalham F,Almutairi A,Alsulaiman K,Abdel Gadir AG

更新日期：2020-09-20 00:00:00

abstract：BACKGROUND:The introduction of antibiotics into modern medicine has changed clinical care by saving millions of lives. However, misuse of antibiotics has led to their benefits being overshadowed by the development of antimicrobial resistance. AIMS OF STUDY:This study aimed to assess university students' knowledge and ...

journal_title：Expert review of anti-infective therapy

authors： Haque M,Rahman NAA,McKimm J,Binti Abdullah SL,Islam MZ,Zulkifli Z,Saidin NB,Azhar NIK,Binti Lutfi SNN,Binti Othman NSA

更新日期：2019-04-01 00:00:00

abstract：:Nitazoxanide (Alinia, Romark Laboratories) was synthesized based on the structure of niclosamide. In vitro studies have demonstrated activity against a broad range of parasites as well as some bacteria. Three controlled trials demonstrated efficacy in cryptosporidiosis, however, the efficacy in advanced AIDS patients ...

journal_title：Expert review of anti-infective therapy

authors： White CA Jr

更新日期：2004-02-01 00:00:00

abstract：:The advent of highly active antiretroviral therapy (HAART) has revolutionized the treatment of HIV. A wide variety of antiretroviral agents are now available, allowing patients and physicians a choice of effective therapy. However, drug resistance and toxicities are emerging as major treatment challenges in the HAART ...

journal_title：Expert review of anti-infective therapy

authors： Jones R,Gazzard B

更新日期：2006-04-01 00:00:00

abstract：:Coinfection with hepatitis C in HIV-infected patients has been reported in 15-70% of patients depending on the mode of acquisition of both viruses. As recent advances in HIV-directed antiviral therapy have markedly delayed HIV progression and mortality, the incidence of complications arising from hepatitis C-associate...

journal_title：Expert review of anti-infective therapy

authors： Vyas JJ,Brown RS,Gaglio PJ

更新日期：2003-10-01 00:00:00

abstract：:In this article we focus on the pathogenesis and clinical characteristics of schistosomiasis infection on the lung vasculature. Overall, the basic biology and understanding of Schistosoma immune responses and their effect on the cardiopulmonary system is limited in both animal and human models, which hinders clinical ...

journal_title：Expert review of anti-infective therapy

authors： Kolosionek E,Crosby A,Harhay MO,Morrell N,Butrous G

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an important emerging respiratory pathogen. MERS-CoV resulted in multiple hospital outbreaks within and outside the Arabian Peninsula. The disease has a high case fatality rate, with the need for a therapeutic option. Areas covered: In this rev...

journal_title：Expert review of anti-infective therapy

authors： Al-Tawfiq JA,Memish ZA

更新日期：2017-03-01 00:00:00

abstract：:Healthy children are high transmitters of influenza and can experience poor influenza outcomes. Many questions remain about the efficacy and impect of preventive measures because most existing studies report imprecise proxies of influenza incidence, do not follow subjects throughout the entire influenza season and acr...

journal_title：Expert review of anti-infective therapy

authors： Lee BY,Shah M

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:In December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak occurred and caused the coronavirus disease of 2019 (COVID-19), which affected ~ 190 countries. The World Health Organization (WHO) has declared COVID-19 a pandemic on 11 March 2020. AREA COVERED:In the review, a com...

journal_title：Expert review of anti-infective therapy

authors： Bhagat S,Yadav N,Shah J,Dave H,Swaraj S,Tripathi S,Singh S

更新日期：2020-12-07 00:00:00

abstract：:Malaria is a curable disease, provided timely access to efficacious drugs is sought. Poor quality and, in particular, falsified antimalarial drugs harm the population of malaria endemic areas; they put lives in peril, cause economic losses to patients, families, industry, and generally undermine the trust in health sy...

journal_title：Expert review of anti-infective therapy

authors： Chaccour C,Kaur H,Del Pozo JL

更新日期：2015-04-01 00:00:00

abstract：:Despite significant advances in the day-to-day management of patients receiving hematopoietic stem cell transplantations, including the introduction of new antiviral drugs, cytomegalovirus (CMV) infection continues to be a major cause of morbidity and mortality. The aim of this article is to undertake a literature-bas...

journal_title：Expert review of anti-infective therapy

authors： Bacigalupo A,Boyd A,Slipper J,Curtis J,Clissold S

更新日期：2012-11-01 00:00:00

abstract：:Tuberculosis continues to be a major health problem worldwide, affecting millions of people each year. Accurate and rapid diagnosis is key to controlling the disease, yet the traditional tests for TB produce results that are either inaccurate or take too long to be definitive. A fast and reliable diagnostic method tha...

journal_title：Expert review of anti-infective therapy

authors： Al-Zamel FA

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Neuraminidase inhibitors (NAIs) reduce influenza symptoms but clear evidence of relationships between viral titer reduction and symptom alleviation is lacking. This open-label, randomized study evaluated differences in viral dynamics between NAIs, and relationships between viral dynamics and influenza sympto...

journal_title：Expert review of anti-infective therapy

authors： Hirotsu N,Saisho Y,Hasegawa T,Shishido T

更新日期：2018-02-01 00:00:00

abstract：:Influenza has circulated among humans for centuries and kills more people than many newly emerging diseases. The present methods for control of influenza are not adequate, especially for dealing with a pandemic. In the face of a rapidly spreading outbreak, a race to isolate the virus and prepare a vaccine would probab...

journal_title：Expert review of anti-infective therapy

authors： Epstein SL

更新日期：2003-12-01 00:00:00

abstract：:Diarrhea is the second largest cause of mortality worldwide in children from the perinatal period to the age of 5 years. Rotavirus has been the most commonly identified viral cause of diarrhea in children. Norovirus is now recognized as the second most common viral pathogen. Adenovirus, astrovirus and sapovirus are th...

journal_title：Expert review of anti-infective therapy

authors： Anderson EJ

更新日期：2010-02-01 00:00:00

abstract：:The constant new emergence of life-threatening human respiratory viral pathogens presents new challenges to clinicians who are left with no available therapeutic interventions. Highly pathogenic strains of influenza A virus (IAV) share an enhanced capacity to propagate to the lower airways and paralyze alveolar macrop...

journal_title：Expert review of anti-infective therapy

authors： Coulombe F,Divangahi M

更新日期：2014-11-01 00:00:00

abstract：:Multidrug chemotherapy for 6-9-months is one of the primary treatments in effective control of tuberculosis, although the mechanisms underlying the persistence of its etiological agent, Mycobacterium tuberculosis, against antibiotics remain unclear. Ever-mounting evidence indicates that the survival of many environmen...

journal_title：Expert review of anti-infective therapy

authors： Islam MS,Richards JP,Ojha AK

更新日期：2012-09-01 00:00:00