An overview of nanotechnology-based treatment approaches against Helicobacter Pylori.

Abstract:

:Introduction: Helicobacter Pylori (H.Pylori) is a pathogen that infects about 50% of the world's population and is known to be responsible for gastroduodenal diseases such as atrophic gastritis, peptic ulcer and stomach cancer. Nowadays, there is no treatment that ensures complete eradication. In addition, resistance to antibiotics used in the current treatment adversely affects the success rates in the fight against infection. Areas covered: This article take attention to treatment approaches using nanoparticles as an alternative to H.Pylori treatment to cope with increased antibiotic resistance. The purpose of this review is to provide an overview of the current limitations and new promising altenatives in treatment of H.Pylori, to highlight the location of nanotechnology to overcome treatment failures, and to emphasize the advantages of using membrane-coated nanoparticles for the first time. Expert opinion: Because of the current problems in the treatment of H.Pylori, there is increasing interest in alternative approaches including nanotechnology. The strong antibacterial effects of metallic nanoparticles, the advantages of polymeric nanoparticles in drug delivery and drug protection, and the prominent properties of membrane-coated nanoparticles in direct targeting demonstrate the significance of nanotechnology in developing new approaches for treatment of H.Pylori infection.

authors

Safarov T,Kiran B,Bagirova M,Allahverdiyev AM,Abamor ES

doi

10.1080/14787210.2019.1677464

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

829-840

issue

10

eissn

1478-7210

issn

1744-8336

journal_volume

17

pub_type

杂志文章,评审
  • Treatment of neurocysticercosis: is it beneficial?

    abstract::Neurocysticercosis is the most common parasitic disease of the CNS. Intracranial neurocysticercosis is classified into cerebral parenchymal and extraparenchymal forms (subarachnoidal and intraventricular). Current medical therapy for parenchymal and extraparenchymal neurocysticercosis invovles the use of anticysticerc...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章

    doi:10.1586/14787210.6.4.435

    authors: Garg RK

    更新日期:2008-08-01 00:00:00

  • Natural killer cells in immunodefense against infective agents.

    abstract::Following the discovery of innate immune receptors, the topics of innate immunity and its role in defense against infective agents have recently blossomed into very active research fields, after several decades of neglect. Among innate immune cells, natural killer (NK) cells are endowed with the unique ability to reco...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.6.6.867

    authors: Zucchini N,Crozat K,Baranek T,Robbins SH,Altfeld M,Dalod M

    更新日期:2008-12-01 00:00:00

  • Detection and diagnosis of Mycobacterium tuberculosis.

    abstract::Tuberculosis continues to be a major health problem worldwide, affecting millions of people each year. Accurate and rapid diagnosis is key to controlling the disease, yet the traditional tests for TB produce results that are either inaccurate or take too long to be definitive. A fast and reliable diagnostic method tha...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/eri.09.92

    authors: Al-Zamel FA

    更新日期:2009-11-01 00:00:00

  • Incidence and risk factors of carbapenem-resistant Enterobacteriaceae infection in intensive care units: a matched case-control study.

    abstract:BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) infection is associated with intensive care admissions, morbidity, and mortality. Our study aimed to determine the incidence, risk factors, and patient outcomes of CRE in the ICU units. METHODS:This was a retrospective matched case-control study of patients admi...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章

    doi:10.1080/14787210.2020.1822736

    authors: Aleidan FAS,Alkhelaifi H,Alsenaid A,Alromaizan H,Alsalham F,Almutairi A,Alsulaiman K,Abdel Gadir AG

    更新日期:2020-09-20 00:00:00

  • Sertaconazole: updated review of a topical antifungal agent.

    abstract::Sertaconazole is an imidazole-type antifungal agent that has shown considerable in vitro activity against pathogenic fungi. Various studies carried out in animal models, clinical and toxicologic trials have confirmed the value of sertaconazole in the topical treatment of superficial mycoses in dermatology and gynecolo...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.3.3.333

    authors: Carrillo-Muñoz AJ,Giusiano G,Ezkurra PA,Quindós G

    更新日期:2005-06-01 00:00:00

  • Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections.

    abstract::Tuberculosis (TB) is mainly an intracellular infection of the lung alveolar macrophages, and any anti-TB agent must therefore be active at the macrophage. Among the available therapies, isoniazid and rifampicin are the most effective drugs against susceptible Mycobacterium tuberculosis, but they are ineffective agains...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/eri.10.20

    authors: Viveiros M,Martins M,Couto I,Rodrigues L,Machado D,Portugal I,Amaral L

    更新日期:2010-04-01 00:00:00

  • Immunological options for the treatment of tuberculosis: evaluation of novel therapeutic approaches.

    abstract::The emergence of multidrug-resistant tuberculosis strains and the coinfection with HIV, together with advances in immunology, have led to renewed interest regarding ways to exploit the immune responses against Mycobacterium tuberculosis therapeutically. Here we review the fundamentals of tuberculosis therapy in view o...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.5.3.461

    authors: Achkar JM,Casadevall A,Glatman-Freedman A

    更新日期:2007-06-01 00:00:00

  • Advances in the epidemiology, diagnosis and treatment of cryptosporidiosis.

    abstract::Cryptosporidiosis, the disease caused by protozoa of the genus Cryptosporidium, represents a major public health problem in both developing and developed countries. The infection can be severe and life threatening among immunocompromised individuals, particularly in AIDS patients and in those with primary immunodefici...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.4.3.429

    authors: Cacciò SM,Pozio E

    更新日期:2006-06-01 00:00:00

  • Management of anaerobic infection.

    abstract::The management of anaerobic infection needs to be prompt and appropriate in order to ensure recovery. Management includes the use of hyperbaric oxygen, surgical methods and antimicrobial therapy. Various factors, such as efficacy, bacterial antimicrobial resistance, ability to reach appropriate antimicrobial levels at...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.2.1.153

    authors: Brook I

    更新日期:2004-02-01 00:00:00

  • Treatment options for second-stage gambiense human African trypanosomiasis.

    abstract::Treatment of second-stage gambiense human African trypanosomiasis relied on toxic arsenic-based derivatives for over 50 years. The availability and subsequent use of eflornithine, initially in monotherapy and more recently in combination with nifurtimox (NECT), has drastically improved the prognosis of treated patient...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.2014.959496

    authors: Eperon G,Balasegaram M,Potet J,Mowbray C,Valverde O,Chappuis F

    更新日期:2014-11-01 00:00:00

  • Antibiotics in the first hour: is there new evidence?

    abstract:INTRODUCTION:International guidelines have recommended for many years to start antimicrobials as early as possible in sepsis and shock. This concept has been challenged by the controversial results of experimental studies and clinical cohorts and resulted in intense debate in the literature. This review aims to summari...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章

    doi:10.1080/14787210.2020.1810567

    authors: Dupuis C,Timsit JF

    更新日期:2021-01-01 00:00:00

  • Risk of infection associated with anti-TNF-α therapy.

    abstract:INTRODUCTION:The advent, more than two decades ago, of monoclonal antibodies and soluble receptors targeting tumor necrosis factor (TNF)-α has revolutionized the therapeutic approach to otherwise difficult-to-treat autoimmune and inflammatory diseases. However, due to the pleiotropic functions played by this pro-inflam...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1080/14787210.2018.1544490

    authors: Fernández-Ruiz M,Aguado JM

    更新日期:2018-12-01 00:00:00

  • Procalcitonin-guided antibiotic therapy for chronic obstructive pulmonary disease exacerbations.

    abstract::The aim of this article is to review the current literature examining the use of procalcitonin-guided antibiotic therapy for management of chronic obstructive pulmonary disease (COPD) exacerbations. Procalcitonin is a serum marker that rises in response to bacterial infections, but remains low in nonbacterial infectio...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/eri.11.45

    authors: Tokman S,Schuetz P,Bent S

    更新日期:2011-06-01 00:00:00

  • Post-exposure prophylaxis for HIV infection.

    abstract::Post-exposure prophylaxis (PEP) with antiretrovirals is now widely used worldwide after either occupational contact (with blood or another blood-containing fluid), or nonoccupational contact (mainly sexual or injection-drug use). It is assumed to reduce the risk of HIV transmission by at least 80%, although its effica...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/eri.11.20

    authors: Rey D

    更新日期:2011-04-01 00:00:00

  • Antiparasitic treatment for solitary cysticercus granuloma: to treat or not to treat?

    abstract::Neurocysticercosis is a major cause of neurologic disease worldwide. In India and other developing countries, single small enhancing computed tomographic lesions representing solitary cysticercus granuloma are a common cause of new-onset seizures. The interesting feature of these solitary enhancing lesions is their sp...

    journal_title:Expert review of anti-infective therapy

    pub_type: 评论,杂志文章

    doi:10.1586/14787210.6.1.15

    authors: Garg RK

    更新日期:2008-02-01 00:00:00

  • Novel corona virus (COVID-19) pandemic: current status and possible strategies for detection and treatment of the disease.

    abstract:INTRODUCTION:In December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak occurred and caused the coronavirus disease of 2019 (COVID-19), which affected ~ 190 countries. The World Health Organization (WHO) has declared COVID-19 a pandemic on 11 March 2020. AREA COVERED:In the review, a com...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章

    doi:10.1080/14787210.2021.1835469

    authors: Bhagat S,Yadav N,Shah J,Dave H,Swaraj S,Tripathi S,Singh S

    更新日期:2020-12-07 00:00:00

  • Risk factors for West Nile virus infection and disease in populations and individuals.

    abstract::West Nile virus (WNV) is a mosquito-borne enveloped positive-strand RNA virus that emerged in North America in 1999 in New York City. Over the past 15 years, WNV has become established throughout the USA and has spread into Canada, Mexico and the Caribbean. CDC reports indicate >41,000 clinical cases, including more t...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.2015.1007043

    authors: Montgomery RR,Murray KO

    更新日期:2015-03-01 00:00:00

  • Is it time to revisit routine administration of antibiotic for preterm prelabor rupture of membranes?

    abstract::Preterm prelabor rupture of membranes (pPROM) is the precursor of up to 40% of preterm deliveries and an independent risk factor for neonatal disease, death and long-term pulmonary and neurodevelopmental deficits. A significant proportion of cases of pPROM are infection driven, although these are difficult to delineat...

    journal_title:Expert review of anti-infective therapy

    pub_type: 评论,杂志文章

    doi:10.1586/14787210.5.4.551

    authors: Ugwumadu A

    更新日期:2007-08-01 00:00:00

  • Developing novel strategies to prevent parasitic infections.

    abstract::The 49th Annual Spring Meeting of the British Society of Parasitology was held at Nottingham University, UK, on 11-14 April 2011. Although a meeting of a national parasitological society, the meeting attracted approximately 375 delegates from 30 countries worldwide. Of the various themes at this meeting, two were focu...

    journal_title:Expert review of anti-infective therapy

    pub_type:

    doi:10.1586/eri.11.62

    authors: Staines HM,Croft SL,Horrocks PD

    更新日期:2011-07-01 00:00:00

  • Does lopinavir/ritonavir alter the primary gingival epithelium?

    abstract::In clinical practice, a significant proportion of HIV-infected patients receive lopinavir/ritonavir (LPV/r) as a component of highly active antiretroviral therapy (HAART). The study by Israr et al. was designed to evaluate the effects of the HIV protease inhibitor LPV/r on gingival epithelium growth and differentiatio...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章

    doi:10.1586/eri.10.138

    authors: Rivero A,Pérez-Camacho I

    更新日期:2010-12-01 00:00:00

  • Extended or continuous versus short-term intravenous infusion of cephalosporins: a meta-analysis.

    abstract::The authors sought to study whether extended or continuous infusion of cephalosporins is associated with better clinical outcomes than short-term infusion. PubMed and Scopus databases were systematically searched. Studies reporting the clinical outcomes of patients receiving extended or continuous infusion (≥3 or 24 h...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,meta分析

    doi:10.1586/eri.13.44

    authors: Korbila IP,Tansarli GS,Karageorgopoulos DE,Vardakas KZ,Falagas ME

    更新日期:2013-06-01 00:00:00

  • Anthrax, toxins and vaccines: a 125-year journey targeting Bacillus anthracis.

    abstract::Bacillus anthracis is the causative agent of anthrax, a disease that plagues both humans and various animal species. Effective vaccines are available, but those approved for human use are crude culture supernatants that require multiple injections and a yearly boost. Many experts agree that it is now time for the next...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.7.2.219

    authors: Tournier JN,Ulrich RG,Quesnel-Hellmann A,Mohamadzadeh M,Stiles BG

    更新日期:2009-03-01 00:00:00

  • Aminoglycosides against carbapenem-resistant Enterobacteriaceae in the critically ill: the pitfalls of aminoglycoside susceptibility.

    abstract:INTRODUCTION:The emergence of carbapenem-resistant Enterobacteriaceae (CRE) has brought aminoglycosides to the frontline since an aminoglycoside may be the only antimicrobial to which CRE isolates show in vitro susceptibility. The appropriateness of aminoglycoside-based therapies for severe infections by CRE is discuss...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1080/14787210.2017.1316193

    authors: Zavascki AP,Klee BO,Bulitta JB

    更新日期:2017-06-01 00:00:00

  • Diagnosis of latent Mycobacterium tuberculosis infection: is the demise of the Mantoux test imminent?

    abstract::Tuberculosis is responsible for more then 2 million deaths worldwide each year and vies with HIV as the world's most fatal infectious disease. In many developing countries, attempts to control the spread of infection rely solely on identification and treatment of those with active disease, ignoring subclinical infecti...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14787210.3.6.981

    authors: Rothel JS,Andersen P

    更新日期:2005-12-01 00:00:00

  • Rifaximin: a nonsystemic rifamycin antibiotic for gastrointestinal infections.

    abstract::Use of nonsystemic antimicrobials with activity against enteropathogens is a promising approach for treatment of infectious diarrhea and other nonsystemic gastrointestinal infections. Rifaximin is approved by the US FDA for the treatment of travelers' diarrhea caused by noninvasive strains of Escherichia coli in patie...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章

    doi:10.1586/eri.10.58

    authors: Cottreau J,Baker SF,DuPont HL,Garey KW

    更新日期:2010-07-01 00:00:00

  • Kingella kingae infections of the skeletal system in children: diagnosis and therapy.

    abstract::As the result of improved bacteriological techniques, Kingella kingae is emerging as an important cause of infections of the skeletal system in children younger than 2 years of age. This review details the bacteriological features and detection methods of this pathogen, as well as the epidemiology, clinical presentati...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/14789072.2.5.787

    authors: Yagupsky P

    更新日期:2004-10-01 00:00:00

  • Pulmonary bacterial coinfection in infants and children with viral respiratory infection.

    abstract::The true incidence of pulmonary bacterial coinfection in infants and children hospitalized with a viral respiratory infection is difficult to ascertain but can vary widely from under 1 to 44%. For the same patient group admitted to pediatric intensive care units and/or requiring ventilatory support, the evidence is mo...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/eri.12.80

    authors: Thorburn K,Riordan A

    更新日期:2012-08-01 00:00:00

  • Prevention and treatment of viral diarrhea in pediatrics.

    abstract::Diarrhea is the second largest cause of mortality worldwide in children from the perinatal period to the age of 5 years. Rotavirus has been the most commonly identified viral cause of diarrhea in children. Norovirus is now recognized as the second most common viral pathogen. Adenovirus, astrovirus and sapovirus are th...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1586/eri.10.1

    authors: Anderson EJ

    更新日期:2010-02-01 00:00:00

  • Management of candidemia in patients with Clostridium difficile infection.

    abstract:INTRODUCTION:Patients with C. difficile infection (CDI) experience intestinal microflora changes that can promote the overgrowth and subsequent translocation of gut resident pathogens into the blood. Consistently, CDI due to PCR-ribotype 027 strain, severe or relapsing CDI, and treatment with high-dosage vancomycin are...

    journal_title:Expert review of anti-infective therapy

    pub_type: 杂志文章,评审

    doi:10.1080/14787210.2016.1197118

    authors: Falcone M,Venditti M,Sanguinetti M,Posteraro B

    更新日期:2016-07-01 00:00:00

  • Hepatitis C infection of B lymphocytes: more tools to address pending questions.

    abstract::Hepatitis C virus (HCV) infection spreads primarily via contact with infected blood and can establish a persistent infection in 80% of infected individuals, progressively causing chronic liver disease that can lead to hepatocellular carcinoma or end-stage liver disease requiring a transplant. There is no vaccine, and ...

    journal_title:Expert review of anti-infective therapy

    pub_type: 评论,杂志文章

    doi:10.1586/eri.10.86

    authors: Stamataki Z

    更新日期:2010-09-01 00:00:00