Chemical-Free Technique to Study the Ultrastructure of Primary Cilium.

abstract：:The slow-growing genus Bradyrhizobium is biologically important in soils, with different representatives found to perform a range of biochemical functions including photosynthesis, induction of root nodules and symbiotic nitrogen fixation and denitrification. Consequently, the role of the genus in soil ecology and bio...

journal_title：Scientific reports

authors： Jones FP,Clark IM,King R,Shaw LJ,Woodward MJ,Hirsch PR

更新日期：2016-05-10 00:00:00

abstract：:Activation of the inflammasome is involved in the progression of retinal degenerative diseases, in particular, in the pathogenesis of Age-Related Macular Degeneration (AMD), with NLRP3 activation the focus of many investigations. In this study, we used genetic and pharmacological approaches to explore the role of the ...

journal_title：Scientific reports

authors： Wooff Y,Fernando N,Wong JHC,Dietrich C,Aggio-Bruce R,Chu-Tan JA,Robertson AAB,Doyle SL,Man SM,Natoli R

更新日期：2020-02-10 00:00:00

abstract：:Determining oil migration distances from source rocks to reservoirs can greatly help in the search for new petroleum accumulations. Concentrations and ratios of polar organic compounds are known to change due to preferential sorption of these compounds in migrating oils onto immobile mineral surfaces. However, these c...

journal_title：Scientific reports

authors： Zhang L,Li M,Wang Y,Yin QZ,Zhang W

更新日期：2013-01-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) development is a multistage process includes the normal, dysplasia and squamous cell carcinoma (SCC) stages. Recently, increasing evidence has suggested that the tumor microenvironment (TME) is an integral part of malignant transformation. Exploring certain key node genes ...

journal_title：Scientific reports

authors： Wu T,Hong Y,Jia L,Wu J,Xia J,Wang J,Hu Q,Cheng B

更新日期：2016-02-01 00:00:00

abstract：:Routine antimicrobial susceptibility testing (AST) can prevent deaths due to bacteria and reduce the spread of multi-drug-resistance, but cannot be regularly performed in resource-limited-settings due to technological challenges, high-costs, and lack of trained professionals. We demonstrate an automated and cost-effec...

journal_title：Scientific reports

authors： Feng S,Tseng D,Di Carlo D,Garner OB,Ozcan A

更新日期：2016-12-15 00:00:00

abstract：:Conventional effluent trading systems (ETSs) between point sources (PSs) and nonpoint sources (NPSs) are often unreliable because of the uncertain characteristics of NPSs. In this study, a new framework was established for PS-NPS ETSs, and a comprehensive analysis was conducted by quantifying the impacts of the uncert...

journal_title：Scientific reports

authors： Chen L,Han Z,Wang G,Shen Z

更新日期：2016-07-11 00:00:00

abstract：:Candida glabrata CCTCC M202019 as an industrial yeast strain that is widely used to produce α-oxocarboxylic acid. Strain M202019 has been proven to have a higher pyruvate-producing capacity than the reference strain CBS138. To characterize the genotype of the M202019 strain, we generated a draft sequence of its genome...

journal_title：Scientific reports

authors： Xu N,Ye C,Chen X,Liu J,Liu L,Chen J

更新日期：2016-10-07 00:00:00

abstract：:Focal adhesion kinase (FAK) is a 125 kDa protein recruited as a participant in focal adhesion dynamics and serves as a signaling scaffold for the assembly and subsequent maturation of focal contact. Identification of new FAK binding proteins could reveal potential signaling targets and contribute to further developmen...

journal_title：Scientific reports

authors： Nguyen BT,Pyun JC,Lee SG,Kang MJ

更新日期：2019-09-09 00:00:00

abstract：:Thrombin-induced and proteinase-activated receptor 1 (PAR1)-mediated signaling increases ROS production, activates ERK, and promotes inflammation and fibroblast proliferation in bleomycin-induced lung injury. Stanniocalcin-1 (STC1) activates anti-oxidant pathways, inhibits inflammation and provides cytoprotection; hen...

journal_title：Scientific reports

authors： Huang L,Zhang L,Ju H,Li Q,Pan JS,Al-Lawati Z,Sheikh-Hamad D

更新日期：2015-12-07 00:00:00

abstract：:This study aims to evaluate the radiation dosimetry of a new technetium-99m‒labelled small-molecule inhibitor of prostate-specific membrane antigen (HYNIC-Glu-Urea-A, 99mTc-HYNIC-PSMA) and its feasibility as a tumor-imaging agent in prostate cancer (PCa) patients. A total of 15 PCa patients were enrolled in this study...

journal_title：Scientific reports

authors： Zhang J,Zhang J,Xu X,Lu L,Hu S,Liu C,Cheng J,Song S,Zhang Y,Shi LQ

更新日期：2020-03-06 00:00:00

abstract：:Studies of past human-landscape interactions rely upon the integration of archaeological, biological and geological information within their geographical context. However, detecting the often ephemeral traces of human activities at a landscape scale remains difficult with conventional archaeological field survey. Geop...

journal_title：Scientific reports

authors： De Smedt P,Van Meirvenne M,Herremans D,De Reu J,Saey T,Meerschman E,Crombé P,De Clercq W

更新日期：2013-01-01 00:00:00

abstract：:At the moment it is unknown to what extent the impaired function of T lymphocytes in ESRD patients depends on uremia, and to what extent on hemodialysis (HD) procedure. Therefore, the purpose of the study was to evaluate percentages of T lymphocyte subpopulations ex vivo, plasma concentrations of IL12p70, TNF, IL-10, ...

journal_title：Scientific reports

authors： Lisowska KA,Pindel M,Pietruczuk K,Kuźmiuk-Glembin I,Storoniak H,Dębska-Ślizień A,Witkowski JM

更新日期：2019-03-25 00:00:00

abstract：:Transjugular intrahepatic portosystemic shunt (TIPS) is an effective therapy for reducing portal pressure. Hepatic myelopathy (HM), a rare complication of chronic liver diseases, remains obscure in terms of treatment and prognosis. We aimed to determine an optimal treat strategy for patients with HM after TIPS. Twenty...

journal_title：Scientific reports

authors： Zhao H,Yue Z,Wang L,Fan Z,He F,Dong X,Liu F

更新日期：2018-10-12 00:00:00

abstract：:This work highlights the possibility of using microstructured fibres with predefined doped regions to produce functional microstructures at a fibre facet with differential chemical etching. A specially designed silica microstructured fibre (MSF) that possesses specific boron-doped silica regions was fabricated for the...

journal_title：Scientific reports

authors： Fu Y,Morency S,Bachus K,Simon D,Hutama T,Gibson GTT,Messaddeq Y,Oleschuk RD

更新日期：2016-02-19 00:00:00

abstract：:Settling due to gravity force is a basic transport mechanism of solid particles in fluids in the Earth. A large portion of particles occurring in nature and used in technical applications are non-spherical. Settling of particles is usually studied in homogeneous ambient conditions, however, stratification is inherent ...

journal_title：Scientific reports

authors： Mrokowska MM

更新日期：2018-01-11 00:00:00

abstract：:A new semiconducting phase of two-dimensional phosphorous in the Kagome lattice is proposed from first-principles calculations. The band gaps of the monolayer (ML) and bulk Kagome phosphorous (Kagome-P) are 2.00 and 1.11 eV, respectively. The magnitude of the band gap is tunable by applying the in-plane strain and/or ...

journal_title：Scientific reports

authors： Chen PJ,Jeng HT

更新日期：2016-03-16 00:00:00

abstract：:A comprehensive identification of sphingoid bases and ceramides in wild Cordyceps was performed by integrating a sequential chromatographic enrichment procedure and an UHPLC-ultrahigh definition-Q-TOF-MS based sphingolipidomic approach. A total of 43 sphingoid bases and 303 ceramides were identified from wild Cordycep...

journal_title：Scientific reports

authors： Mi JN,Han Y,Xu Y,Kou J,Wang JR,Jiang ZH

更新日期：2016-12-14 00:00:00

abstract：:The Na(3p) + H2(X1Σg+) → NaH(X1Σ+) + H(2S) reaction plays an important role in the field of diabatic reaction dynamics. A set of new diabatic potential energy surfaces (PESs) of the NaH2 system are structured, which include the diabatic coupling between the lowest two adiabatic states. The electronic structure calcula...

journal_title：Scientific reports

authors： Wang S,Yang Z,Yuan J,Chen M

更新日期：2018-12-19 00:00:00

abstract：:Adherence to cardioprotective medications following myocardial infarction (MI) is commonly assessed using a binary threshold of 80%. We investigated the relationship between medication adherence as a continuous measure and outcomes in MI survivors using restricted cubic splines (RCS). We identified all patients aged ≥...

journal_title：Scientific reports

authors： Greenland M,Knuiman MW,Hung J,Nedkoff L,Arnet I,Rankin JM,Kilkenny MF,Sanfilippo FM

更新日期：2020-03-09 00:00:00

abstract：:α-Dystroglycanopathy (α-DGP) is a group of muscular dystrophy characterized by abnormal glycosylation of α-dystroglycan (α-DG), including Fukuyama congenital muscular dystrophy (FCMD), muscle-eye-brain disease, Walker-Warburg syndrome, and congenital muscular dystrophy type 1D (MDC1D), etc. LARGE, the causative gene f...

journal_title：Scientific reports

authors： Ohtsuka Y,Kanagawa M,Yu CC,Ito C,Chiyo T,Kobayashi K,Okada T,Takeda S,Toda T

更新日期：2015-02-09 00:00:00

abstract：:We investigated the surface reformation of poly(dimethylsiloxane) (PDMS) elastomers by means of ion beam bombardment for fabricating wrinkle structures. Oxidation on the PDMS surface formed a silica-like outer layer that interacted with the inner PDMS layer, leading to the formation of wrinkle structures that minimize...

journal_title：Scientific reports

authors： Park HG,Jeong HC,Jung YH,Seo DS

更新日期：2015-07-21 00:00:00

abstract：:Mobile phone microscopes are a natural platform for point-of-care imaging, but current solutions require an externally powered illumination source, thereby adding bulk and cost. We present a mobile phone microscope that uses the internal flash or sunlight as the illumination source, thereby reducing complexity whilst ...

journal_title：Scientific reports

authors： Orth A,Wilson ER,Thompson JG,Gibson BC

更新日期：2018-02-19 00:00:00

abstract：:Treatment options for chronic spinal cord injury (SCI) remain limited due to unfavourable changes in the microenvironment. Gene therapy can overcome these barriers through continuous delivery of therapeutic gene products to the target tissue. In particular, adeno-associated virus (AAV) vectors are potential candidates...

journal_title：Scientific reports

authors： Hoshino Y,Nishide K,Nagoshi N,Shibata S,Moritoki N,Kojima K,Tsuji O,Matsumoto M,Kohyama J,Nakamura M,Okano H

更新日期：2019-07-08 00:00:00

abstract：:We aimed to develop a brief, preclinical test to screen the reduced hippocampal volume that is a marker of early dementia [Cognitive Quotient (CQ) test]. We performed an observational study of adult subjects who underwent brain MRI in seven institutions from February 2018 to May 2019. The CQ test consists of five comp...

journal_title：Scientific reports

authors： Kasai W,Goto T,Aoyama Y,Sato K

更新日期：2020-10-07 00:00:00

abstract：:We evaluate the track segment yield G' of typical water radiolysis products (eaq-, ·OH and H2O2) under heavy ions (He, C and Fe ions) using a Monte Carlo simulation code in the Geant4-DNA. Furthermore, we reproduce experimental results of ·OH of He and C ions around the Bragg peak energies (< 6 MeV/u). In the relative...

journal_title：Scientific reports

authors： Baba K,Kusumoto T,Okada S,Ogawara R,Kodaira S,Raffy Q,Barillon R,Ludwig N,Galindo C,Peaupardin P,Ishikawa M

更新日期：2021-01-15 00:00:00

abstract：:This study evaluated the antibacterial effects of short-time exposure of surface pre-reacted glass-ionomer (S-PRG) eluate on oral microcosm biofilm. Biofilms were treated with an S-PRG eluate at different concentrations (25%, 50%, and 100%), distilled water (DW), and 0.1% chlorhexidine (CHX) twice a day for 5 min repe...

journal_title：Scientific reports

authors： Kim HJ,Cho MY,Lee ES,Jung HI,Kim BI

更新日期：2020-09-02 00:00:00

abstract：:Lepisosteoids are known for their evolutionary conservatism, and their body plan can be traced at least as far back as the Early Cretaceous, by which point two families had diverged: Lepisosteidae, known since the Late Cretaceous and including all living species and various fossils from all continents, except Antarcti...

journal_title：Scientific reports

authors： Brito PM,Alvarado-Ortega J,Meunier FJ

更新日期：2017-12-19 00:00:00

abstract：:The whale shark (Rhincodon typus) is an endangered species with a declining global population. The South Ari Atoll Marine Protected Area (SAMPA), Maldives, is one of few locations globally where year-long residency of individuals occurs. This SAMPA aggregation appears to consist almost exclusively of immature males. D...

journal_title：Scientific reports

authors： Harvey-Carroll J,Stewart JD,Carroll D,Mohamed B,Shameel I,Zareer IH,Araujo G,Rees R

更新日期：2021-01-13 00:00:00

abstract：:Recent studies demonstrated that sinogram affirmed iterative reconstructions (SAFIRE) can produce higher-resolution images with greater robustness for the reduction of various imaging artefacts. Eighty-five patients were prospectively evaluated and underwent a high-pitch spiral acquisition CT scan. In-stent noise, sig...

journal_title：Scientific reports

authors： Yang J,Yang X,De Cecco CN,Duguay TM,Chen Z,Tesche C,Schoepf UJ,Chen Y

更新日期：2017-07-31 00:00:00

abstract：:There is growing interest in the conservation and utilization of crop wild relatives (CWR) in international food security policy and research. Legumes play an important role in human health, sustainable food production, global food security, and the resilience of current agricultural systems. Pea belongs to the ancien...

journal_title：Scientific reports

authors： Smýkal P,Hradilová I,Trněný O,Brus J,Rathore A,Bariotakis M,Das RR,Bhattacharyya D,Richards C,Coyne CJ,Pirintsos S

更新日期：2017-12-12 00:00:00