Abstract：
:Our understanding of a variety of phenomena in physics, biology and economics crucially depends on the analysis of multivariate time series. While a wide range tools and techniques for time series analysis already exist, the increasing availability of massive data structures calls for new approaches for multidimensional signal processing. We present here a non-parametric method to analyse multivariate time series, based on the mapping of a multidimensional time series into a multilayer network, which allows to extract information on a high dimensional dynamical system through the analysis of the structure of the associated multiplex network. The method is simple to implement, general, scalable, does not require ad hoc phase space partitioning, and is thus suitable for the analysis of large, heterogeneous and non-stationary time series. We show that simple structural descriptors of the associated multiplex networks allow to extract and quantify nontrivial properties of coupled chaotic maps, including the transition between different dynamical phases and the onset of various types of synchronization. As a concrete example we then study financial time series, showing that a multiplex network analysis can efficiently discriminate crises from periods of financial stability, where standard methods based on time-series symbolization often fail.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Lacasa L,Nicosia V,Latora Vdoi
10.1038/srep15508subject
Has Abstractpub_date
2015-10-21 00:00:00pages
15508issn
2045-2322pii
srep15508journal_volume
5pub_type
杂志文章abstract：:Either hardness or toughness has been the core interest in scientific exploration and technological pursuit for a long time. However, it is still a big challenge to enhance the hardness and toughness at the same time, since the improvement of one side is always at the expense of the other one. Here, we have succeeded ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09807-9
更新日期：2017-08-24 00:00:00
abstract：:The aims of the study were to clarify the impact of storage time and centrifugation strategy on brain-derived neurotrophic factor (BDNF) levels in human serum and plasma samples. In addition, we analyzed associations between BDNF levels, cardiorespiratory fitness and waist circumference. Seventeen healthy males (25.2 ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45976-5
更新日期：2019-07-04 00:00:00
abstract：:The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to characterize the effects of spaceflight and reentry to 1 g on the structure and integrity of the retina and blood-retinal barrier (BRB) in the eye. To ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44696-0
更新日期：2019-06-03 00:00:00
abstract：:Axolotls have the amazing ability to regenerate. When compared to humans, axolotls display a very fast wound closure, no scarring and are capable to replace lost appendages perfectly. Understanding the signaling mechanism leading to this perfect healing is a key step to help develop regenerative treatments for humans....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38171-5
更新日期：2019-02-04 00:00:00
abstract：:The mechanism by which chronic metabolic acidosis (CMA) regulates sodium (Na(+))-chloride (Cl(-)) cotransporter (NCC) in the renal distal convoluted tubules remains unexplored. We examined the role of STE20/SPS1-related proline/alanine-rich kinase (SPAK) and with-no-lysine kinase 4 (WNK4) on expression of NCC in mouse...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18360
更新日期：2016-01-05 00:00:00
abstract：:Regulatory T cells (Tregs) expand in peripheral lymphoid organs and can produce immunosuppressive cytokines to support tumor growth. IL-10 abrogation efficiently induces Treg formation but dampens tumoral neuropilin-1 (Nrp-1) Treg signaling, which simultaneously augments Th1 and Th17 immunity. These effects are associ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24249
更新日期：2016-04-14 00:00:00
abstract：:Haze is a serious issue in China with increasing concerns, and understanding the factors driving decadal-scale variations in haze occurrence is relevant for government policymaking. Using a comprehensive observational haze dataset, we demonstrate notable decadal fluctuations in the number of haze days (HD) during wint...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27424
更新日期：2016-06-10 00:00:00
abstract：:Huntington's disease (HD) is caused by CAG repeat expansion in the huntingtin gene. The expanded polyglutamine (polyQ) repeat of the encoded protein leads to protein misfolding and aggregation, resulting in increased neuronal cell death. DNAJ co-chaperones play a crucial role in transferring misfolded/unfolded protein...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65046-5
更新日期：2020-05-18 00:00:00
abstract：:Embryonic cryopreservation has a relatively low survival rate because of cytoskeletal damage. However, molecular anti-freezing mechanisms have been largely unexplored. This study investigated the significance of RhoA, involved in embryonic development, and the Rho/RhoA-associated kinase (ROCK) signalling pathway in cr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07066-2
更新日期：2017-07-27 00:00:00
abstract：:Intrahepatic cholestasis induced by drug toxicity, bile salt export pump (BSEP) deficiency, or pregnancy frequently causes cholestatic liver damage, which ultimately may lead to liver fibrosis and cirrhosis. Here, the preventive and therapeutic effects of peroxisome proliferator-activated receptor α (PPARα) signaling ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10524-6
更新日期：2017-08-30 00:00:00
abstract：:There is increasing interest in the development of noninvasive diagnostic methods for early cancer detection, to improve the survival rate and quality of life of cancer patients. Identification of volatile metabolic compounds may provide an approach for noninvasive early diagnosis of malignant diseases. Here we analyz...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05196
更新日期：2014-06-06 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-25179-0
更新日期：2018-05-10 00:00:00
abstract：:In this paper, we propose a real time, ultrahigh accuracy and full-field-of-view (RUF) algorithm for full field of view (FOV) imaging system. The proposed algorithm combines rough matching and precise matching method to stitch multiple images with the whole FOV in short time and high imaging quality. In order to verif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69353-9
更新日期：2020-07-24 00:00:00
abstract：:The sensing properties of monolayer arsenic phosphorus (AsP) for the adsorption of SF6, H2O, O2, and SF6 decomposition gases (SO2 and H2S) are theoretically investigated by the first-principle calculations. We calculate the adsorption energy, equilibrium distance, Mulliken charge transfer, and electron localization fu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30643-y
更新日期：2018-08-13 00:00:00
abstract：:Maternal low-protein (MLP) diet can lead to hepatic steatosis, which only develops with ageing. It is still unclear whether the young offspring show any signs of past exposure to prenatal adverse conditions. We hypothesized that early nutritional insult would first affect the dynamic responsiveness to nutritional chal...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10380-4
更新日期：2017-08-29 00:00:00
abstract：:By using silver nanoplatelets with a widely tunable localized surface plasmon resonance (LSPR), and their corresponding local field enhancement, here we show large manipulation of plasmonic enhanced upconversion in NaYF4:Yb(3+)/Er(3+) nanocrystals at the single particle level. In particular, we show that when the plas...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10196
更新日期：2015-05-15 00:00:00
abstract：:The probability of mitochondrial permeability transition (mPT) pore opening is inversely related to the magnitude of the proton electrochemical gradient. The module conferring sensitivity of the pore to this gradient has not been identified. We investigated mPT's voltage-sensing properties elicited by calcimycin or H2...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26700
更新日期：2016-05-25 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-68818-1
更新日期：2020-08-10 00:00:00
abstract：:Honey bees (Apis mellifera) are important pollinators and their health is threatened worldwide by persistent exposure to a wide range of factors including pesticides, poor nutrition, and pathogens. Nosema ceranae is a ubiquitous microsporidian associated with high colony mortality. We used lab micro-colonies of honey ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22042
更新日期：2016-02-25 00:00:00
abstract：:Lavender (Lavandula angustifolia) is an important economic plant because of the value of its essential oil (EO). The Yili Valley in Xinjiang has become the largest lavender planting base in China. However, there is a lack of research on the gene expression regulation of EO biosynthesis and metabolism in local varietie...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63950-4
更新日期：2020-04-24 00:00:00
abstract：:Delivery of proteins has been regarded as the safest and most useful application in therapeutic application of stem cells, because proteins can regulate gene expression transiently without any genomic alteration. However, it is difficult to accurately measure efficiency or quantity of intracellular protein uptake. Her...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04378
更新日期：2014-03-14 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep40037. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/srep46991
更新日期：2018-05-22 00:00:00
abstract：:The aim of this study was to identify the synergistic effect of microRNA expression with classical risk factors of coronary heart disease (CHD) and to explore their diagnostic value for coronary stenotic lesions in subjects with CHD. Plasma samples were obtained from 66 subjects with CHD and from 58 control individual...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14925
更新日期：2015-10-08 00:00:00
abstract：:Waves of any kinds, including sound waves and light waves, can interfere constructively or destructively when they are overlapped, allowing for myriad applications. However, unlike continuous waves of a single frequency, interference of photoacoustic pulses is often overlooked because of their broadband characteristic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep21511
更新日期：2016-02-12 00:00:00
abstract：:SIRT1 is one of seven mammalian homologs of Sir2 that catalyzes NAD(+)-dependent protein deacetylation. The aim of the present study is to explore the effect of SIRT1 small molecule activator on the anticancer activity and the underlying mechanism. We examined the anticancer activity of a novel oral agent, curcumin, w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13429
更新日期：2015-08-24 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-60918-2
更新日期：2020-02-27 00:00:00
abstract：:Diffuse large B-cell lymphoma (DLBCL) is an aggressive lymphoma with diverse outcomes. Concurrent translocation of MYC and BCL-2 and/or BCL-6, and concurrent immunohistochemical (IHC) high expression of MYC and BCL-2, have been linked to unfavorable treatment responses. TP53-mutated DLBCL has also been linked to worse...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33230-3
更新日期：2018-10-04 00:00:00
abstract：:Ice-albedo feedback due to the albedo contrast between water and ice is a major factor in seasonal sea ice retreat, and has received increasing attention with the Arctic Ocean shifting to a seasonal ice cover. However, quantitative evaluation of such feedbacks is still insufficient. Here we provide quantitative eviden...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08467-z
更新日期：2017-08-15 00:00:00
abstract：:In recent years many monoclonal antibodies (mAb) have entered the biotherapeutics market, offering new treatments for chronic and life-threatening diseases. Protein A resin captures monoclonal antibody (mAb) effectively, but the binding capacity decays over repeated purification cycles. On an industrial scale, replaci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30526
更新日期：2016-07-29 00:00:00
abstract：:Measuring toxicity is one of the main steps in drug development. Hence, there is a high demand for computational models to predict the toxicity effects of the potential drugs. In this study, we used a dataset, which consists of four toxicity effects:mutagenic, tumorigenic, irritant and reproductive effects. The propos...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38660
更新日期：2016-12-09 00:00:00
