Mutation of TP53, translocation analysis and immunohistochemical expression of MYC, BCL-2 and BCL-6 in patients with DLBCL treated with R-CHOP.

abstract：:Silica columns from PCR purification and gel extraction kits are widely used in laboratories worldwide to assist in gene cloning. However, the use of these columns can generate plastic waste that has an environmental impact due to their one-off design and massive consumption. Thus, it is important to develop a novel m...

journal_title：Scientific reports

authors： Zhou Y,Zhang Y,He W,Wang J,Peng F,Huang L,Zhao S,Deng W

更新日期：2018-08-27 00:00:00

abstract：:Spectra-structure interrelationship is still the weakness of NIR spectral assignment. In this paper, a comprehensive investigation from chemical structural property to natural chemical compounds was carried out for NIR spectral assignment. Surprisingly, we discovered that NIR absorption frequency of the skeleton struc...

journal_title：Scientific reports

authors： Ma L,Peng Y,Pei Y,Zeng J,Shen H,Cao J,Qiao Y,Wu Z

更新日期：2019-07-01 00:00:00

abstract：:Asymmetric cell division is a ubiquitous feature during the development of higher organisms. Asymmetry is achieved by differential localization or activities of biological molecules such as proteins, and coding and non-coding RNAs. Here, we present subcellular transcriptomic and proteomic analyses along the animal-veg...

journal_title：Scientific reports

authors： Sindelka R,Abaffy P,Qu Y,Tomankova S,Sidova M,Naraine R,Kolar M,Peuchen E,Sun L,Dovichi N,Kubista M

更新日期：2018-05-29 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a common human malignancy with a high incidence rate and poor prognosis. Although astrocyte elevated gene 1 (AEG-1) expression is up-regulated in various human cancers and plays an important role in carcinogenesis and tumour progression, the impact of AEG-1 on the development and...

journal_title：Scientific reports

authors： Wang Y,Wang T,Sun Y,Sun W,Wang X

更新日期：2017-11-13 00:00:00

abstract：:Cyanobacteria harbor unique photoreceptors, designated as cyanobacteriochromes (CBCRs). In this study, we attempted to engineer the chromatic acclimation sensor CcaS, a CBCR derived from the cyanobacterium Synechocystis sp. PCC 6803. The wild-type CcaS induces gene expression under green light illumination and repress...

journal_title：Scientific reports

authors： Nakajima M,Ferri S,Rögner M,Sode K

更新日期：2016-11-24 00:00:00

abstract：:Mitochondrial dysfunction and significant changes in metabolic pathways accompany cancer development and are responsible for maintaining the tumor microenvironment. Normal mitochondria can trigger intrinsic apoptosis by releasing cytochrome c into the cytosol. The survival of malignant cells highly depends on the supp...

journal_title：Scientific reports

authors： Bencze G,Bencze S,Rivera KD,Watson JD,Hidvegi M,Orfi L,Tonks NK,Pappin DJ

更新日期：2020-08-25 00:00:00

abstract：:Critical limb ischemia (CLI) is associated with a high risk of limb amputation. It has been shown that cell therapy is safe and has beneficial effects on ischemic clinical symptoms in patients with CLI. The aim of this study was to further investigate the outcomes of intramuscular injection of autologous bone-marrow m...

journal_title：Scientific reports

authors： Yusoff FM,Kajikawa M,Matsui S,Hashimoto H,Kishimoto S,Maruhashi T,Chowdhury M,Noma K,Nakashima A,Kihara Y,Sueda T,Higashi Y

更新日期：2019-05-22 00:00:00

abstract：:A cerebral aneurysm occurs as a result of a weakened blood vessel, which allows blood to flow into a sac or a ballooned section. Recent advancement shows that a new device, 'flow-diverter', can divert blood flow away from the aneurysm sac. People found that a flow-diverter based on thin film nitinol (TFN), works very ...

journal_title：Scientific reports

authors： Chen Y,Howe C,Lee Y,Cheon S,Yeo WH,Chun Y

更新日期：2016-03-24 00:00:00

abstract：:In this study, real-time and in-situ permittivity measurements under intense microwave electromagnetic fields are proposed as a powerful technique for the study of microwave-enhanced thermal processes in materials. In order to draw reliable conclusions about the temperatures at which transformations occur, we address ...

journal_title：Scientific reports

authors： García-Baños B,Reinosa JJ,Peñaranda-Foix FL,Fernández JF,Catalá-Civera JM

更新日期：2019-07-25 00:00:00

abstract：:Identifying how spatially distributed information becomes integrated in the brain is essential to understanding higher cognitive functions. Previous computational and empirical studies suggest a significant influence of brain network structure on brain network function. However, there have been few analytical approach...

journal_title：Scientific reports

authors： Moon JY,Kim J,Ko TW,Kim M,Iturria-Medina Y,Choi JH,Lee J,Mashour GA,Lee U

更新日期：2017-04-20 00:00:00

abstract：:Xenobiotic resistance is commonly found in species with short generation times such as bacteria, annual plants, and insects. Nevertheless, the fundamental evolutionary principles that govern the spread of resistance alleles hold true for species with longer generation times. One such example could occur with sea lampr...

journal_title：Scientific reports

authors： Christie MR,Sepúlveda MS,Dunlop ES

更新日期：2019-12-03 00:00:00

abstract：:Motion sensitivity impairment in Alzheimer's disease (AD) is often characterized as elevated coherence threshold. An alternative way to measure motion sensitivity is the direction threshold, i.e., the minimal angle of motion direction that can be discriminated. So far, it is less clear whether and how the direction th...

journal_title：Scientific reports

authors： Liu Y,Feng D,Wang H

更新日期：2019-09-10 00:00:00

abstract：:The PDZ domain-containing scaffold protein, syntenin-1, binds to the transmembrane proteoglycan, syndecan-4, but the molecular mechanism/function of this interaction are unknown. Crystal structure analysis of syntenin-1/syndecan-4 cytoplasmic domains revealed that syntenin-1 forms a symmetrical pair of dimers anchored...

journal_title：Scientific reports

authors： Choi Y,Yun JH,Yoo J,Lee I,Kim H,Son HN,Kim IS,Yoon HS,Zimmermann P,Couchman JR,Cho HS,Oh ES,Lee W

更新日期：2016-11-10 00:00:00

abstract：:Stress is one of major factors that cause sleep problems. Hypocretin represents a stress-related neuropeptide and is well known in maintaining physiological wakefulness. The hypocretinergic neurons originate in the lateral hypothalamic area (LHA) and transmit to several brain regions, including the median raphe nuclei...

journal_title：Scientific reports

authors： Hsiao YT,Lo Y,Yi PL,Chang FC

更新日期：2019-06-03 00:00:00

abstract：:Tracking animal behavior by video is one of the most common tasks in the life sciences. Although commercial software exists for executing this task, they often present enormous cost to the researcher and can entail purchasing hardware that is expensive and lacks adaptability. Additionally, the underlying code is often...

journal_title：Scientific reports

authors： Pennington ZT,Dong Z,Feng Y,Vetere LM,Page-Harley L,Shuman T,Cai DJ

更新日期：2019-12-27 00:00:00

abstract：:Transmembrane flux of Cs+ (a K+ congener) was measured in human red blood cells (RBCs; erythrocytes) on the 10-s time scale. This is the first report on dissolution dynamic nuclear polarization (dDNP) nuclear magnetic resonance (NMR) spectroscopy with this nuclide in mammalian cells. Four technical developments regula...

journal_title：Scientific reports

authors： Kuchel PW,Karlsson M,Lerche MH,Shishmarev D,Ardenkjaer-Larsen JH

更新日期：2019-12-23 00:00:00

abstract：:Higher-order connectivity in complex systems described by simplexes of different orders provides a geometry for simplex-based dynamical variables and interactions. Simplicial complexes that constitute a functional geometry of the human connectome can be crucial for the brain complex dynamics. In this context, the best...

journal_title：Scientific reports

authors： Andjelković M,Tadić B,Melnik R

更新日期：2020-10-14 00:00:00

abstract：:Intracellular endogenous fluorescent co-enzymes, reduced nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FAD), play a pivotal role in cellular metabolism; quantitative assessment of their presence in living cells can be exploited to monitor cellular energetics in Parkinson's disease (PD), a n...

journal_title：Scientific reports

authors： Chakraborty S,Nian FS,Tsai JW,Karmenyan A,Chiou A

更新日期：2016-01-13 00:00:00

abstract：:Low phase noise mode-locked fiber laser finds important applications in telecommunication, ultrafast sciences, material science, and biology, etc. In this paper, two types of carbon nano-materials, i.e. single-wall carbon nanotube (SWNT) and graphene oxide (GO), are investigated as efficient saturable absorbers (SAs) ...

journal_title：Scientific reports

authors： Li X,Wu K,Sun Z,Meng B,Wang Y,Wang Y,Yu X,Yu X,Zhang Y,Shum PP,Wang QJ

更新日期：2016-04-29 00:00:00

abstract：:A series of three remarkable complexes [PMo12O40]@[Cu6O(TZI)3(H2O)9]4·OH·31H2O (H3TZI = 5-tetrazolylisophthalic acid; denoted as HLJU-1, HLJU = Heilongjiang University), [SiMo12O40]@[Cu6O(TZI)3(H2O)9]4·32H2O (denoted as HLJU-2), and [PW12O40]@[Cu6O(TZI)3(H2O)6]4·OH·31H2O (denoted as HLJU-3) have been isolated by using...

journal_title：Scientific reports

authors： Sun JW,Yan PF,An GH,Sha JQ,Li GM,Yang GY

更新日期：2016-05-09 00:00:00

abstract：:The nucleotides guanosine tetraphosphate and pentaphosphate (together known as (p)ppGpp or magic spot) are produced in plant plastids from GDP/GTP and ATP by RelA-SpoT homologue (RSH) enzymes. In the model plant Arabidopsis (p)ppGpp regulates chloroplast transcription and translation to affect growth, and is also impl...

journal_title：Scientific reports

authors： Avilan L,Puppo C,Villain A,Bouveret E,Menand B,Field B,Gontero B

更新日期：2019-11-27 00:00:00

abstract：:Decreasing coral cover on the Great Barrier Reef (GBR) may provide opportunities for rapid growth and expansion of other taxa. The bioeroding sponges Cliona spp. are strong competitors for space and may take advantage of coral bleaching, damage, and mortality. Benthic surveys of the inshore GBR (2005-2014) revealed th...

journal_title：Scientific reports

authors： Ramsby BD,Hoogenboom MO,Whalan S,Webster NS,Thompson A

更新日期：2017-06-02 00:00:00

abstract：:DNA focused panel sequencing has been rapidly adopted to assess therapeutic targets in advanced/refractory cancer. Integrated Genomic Profiling (IGP) utilising DNA/RNA with tumour/normal comparisons in a Clinical Laboratory Improvement Amendments (CLIA) compliant setting enables a single assay to provide: therapeutic ...

journal_title：Scientific reports

authors： Borad MJ,Egan JB,Condjella RM,Liang WS,Fonseca R,Ritacca NR,McCullough AE,Barrett MT,Hunt KS,Champion MD,Patel MD,Young SW,Silva AC,Ho TH,Halfdanarson TR,McWilliams RR,Lazaridis KN,Ramanathan RK,Baker A,Aldrich J,

更新日期：2016-12-23 00:00:00

abstract：:Fungus-growing termites forage dead plant materials from the field to cultivate symbiotic Termitomyces fungi in the nest. Termite foraging behavior and the entry of symbiotic arthropod inquilines may transfer nematodes into a nest and adversely affect fungus production. To test whether nematodes were transferred to fu...

journal_title：Scientific reports

authors： Kanzaki N,Liang WR,Chiu CI,Yang CT,Hsueh YP,Li HF

更新日期：2019-06-20 00:00:00

abstract：:β-Glucosidases are enzymes that hydrolyze β-glycosidic bonds to release non-reducing terminal glucosyl residues from glycosides and oligosaccharides, and thus have significant application potential in industries. However, most β-glucosidases are feedback inhibited by the glucose product, which restricts their applicat...

journal_title：Scientific reports

authors： Yang Y,Zhang X,Yin Q,Fang W,Fang Z,Wang X,Zhang X,Xiao Y

更新日期：2015-11-25 00:00:00

abstract：:Rhythms of life are dictated by oscillations, which take place in a wide rage of biological scales. In bacteria, for example, oscillations have been proven to control many fundamental processes, ranging from gene expression to cell divisions. In genetic circuits, oscillations originate from elemental block such as aut...

journal_title：Scientific reports

authors： Ruocco G,Fratalocchi A

更新日期：2014-11-18 00:00:00

abstract：:Data on post stroke outcomes in developing countries are scarce due to uncoordinated healthcare delivery systems. In Malaysia, the national stroke clinical practice guideline does not address transfer of care and longer term post stroke care beyond tertiary care. Hence, post stroke care delivery may be delivered at ei...

journal_title：Scientific reports

authors： Abdul Aziz AF,Ali MF,Yusof MF,Che' Man Z,Sulong S,Aljunid SM

更新日期：2018-12-19 00:00:00

abstract：:Agrostemma githago L. (corn cockle) is an herbaceous plant mainly growing in Europe. The seeds of the corn cockle are toxic and poisonings were widespread in the past by consuming contaminated flour. The toxic principle of Agrostemma seeds was attributed to triterpenoid secondary metabolites. Indeed, this is in part t...

journal_title：Scientific reports

authors： Weise C,Schrot A,Wuerger LTD,Adolf J,Gilabert-Oriol R,Sama S,Melzig MF,Weng A

更新日期：2020-09-21 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease. Increasing the chances of success for future clinical strategies requires more in-depth knowledge of the molecular basis underlying disease heterogeneity. We recently laid the foundation for a molecular taxonomy of ALS by whole-ge...

journal_title：Scientific reports

authors： Morello G,Guarnaccia M,Spampinato AG,Salomone S,D'Agata V,Conforti FL,Aronica E,Cavallaro S

更新日期：2019-07-10 00:00:00

abstract：:Acute kidney injury (AKI) in patients with septic shock is associated with high mortality, but the appropriate timing for initiating continuous renal replacement therapy (CRRT) is controversial. We retrospectively enrolled 158 septic shock patients with AKI in the medical intensive care unit (ICU) from July 2016 to Ap...

journal_title：Scientific reports

authors： Yoon BR,Leem AY,Park MS,Kim YS,Chung KS

更新日期：2019-08-19 00:00:00