Mutation of TP53, translocation analysis and immunohistochemical expression of MYC, BCL-2 and BCL-6 in patients with DLBCL treated with R-CHOP.

abstract：:MALDI-TOF spectrometry has not been used for urinary exosome analysis. We used it for determining UC biomarkers. From 2012 to 2015, we enrolled 129 consecutive patients with UC and 62 participants without UC. Exosomes from their urine were isolated, and analyzed through MALDI-TOF spectrometry. Immunohistochemical (IHC...

journal_title：Scientific reports

authors： Lin SY,Chang CH,Wu HC,Lin CC,Chang KP,Yang CR,Huang CP,Hsu WH,Chang CT,Chen CJ

更新日期：2016-09-30 00:00:00

abstract：:Reporter gene imaging allows for non-invasive monitoring of molecular processes in living cells, providing insights on the mechanisms underlying pathology and therapy. A lysine-rich protein (LRP) chemical exchange saturation transfer (CEST) MRI reporter gene has previously been developed and used to image tumor cells,...

journal_title：Scientific reports

authors： Perlman O,Ito H,Gilad AA,McMahon MT,Chiocca EA,Nakashima H,Farrar CT

更新日期：2020-11-26 00:00:00

abstract：:We present a new method for the design of devices to manipulate the displacement field in Elastic materials. It consists of solving a nonlinear optimization problem where the objective function defines the error in matching a desired displacement field, and the design variables determine the required material distribu...

journal_title：Scientific reports

authors： Fachinotti VD,Peralta I,Albanesi AE

更新日期：2018-06-29 00:00:00

abstract：:Immune parameters show characteristic normal baseline levels and variance in the population. We characterised the degree of inter-individual and within-individual variation over one-year time period in 33 immune cell subsets by flow cytometry in peripheral blood mononuclear cells from 43 healthy young adult volunteers...

journal_title：Scientific reports

authors： Kanodia P,Kaur G,Coshic P,Chatterjee K,Neeman T,George A,Rath S,Bal V,Prabhu SB

更新日期：2019-10-14 00:00:00

abstract：:MicroRNAs are a class of small noncoding RNAs that regulate gene expression post-transcriptionally either by inhibiting protein translation or by causing the degradation of target mRNAs. Current evidence indicates that miR-33b is involved in the regulation of lipid metabolism, cholesterol homeostasis, glucose metaboli...

journal_title：Scientific reports

authors： Lin Y,Liu AY,Fan C,Zheng H,Li Y,Zhang C,Wu S,Yu D,Huang Z,Liu F,Luo Q,Yang CJ,Ouyang G

更新日期：2015-04-28 00:00:00

abstract：:Graphene grown directly on germanium is a possible route for the integration of graphene into nanoelectronic devices as well as it is of great interest for materials science. The morphology of the interface between graphene and germanium influences the electronic properties and has not already been completely elucidat...

journal_title：Scientific reports

authors： Mendoza CD,Figueroa NS,Maia da Costa MEH,Freire FL Jr

更新日期：2019-08-29 00:00:00

abstract：:Reversible polymeric networks can show self-healing properties due to their ability to reassemble after application of stress and fracture, but typically the relation between equilibrium molecular dynamics and self-healing kinetics has been difficult to disentangle. Here we present a well-characterized, self-assembled...

journal_title：Scientific reports

authors： Yan T,Schröter K,Herbst F,Binder WH,Thurn-Albrecht T

更新日期：2016-09-01 00:00:00

abstract：:Celastrol is a leptin-sensitizing agent with profound anti-obesity effects in diet-induced obese (DIO) mice. However, the genes and pathways that mediate celastrol-induced leptin sensitization have not been fully understood. By comparing the hypothalamic transcriptomes of celastrol and vehicle-treated DIO mice, we ide...

journal_title：Scientific reports

authors： Feng X,Guan D,Auen T,Choi JW,Salazar-Hernandez MA,Faruk F,Copps KD,Ozcan U

更新日期：2019-09-05 00:00:00

abstract：:Despite non-structural carbohydrate (NSC) importance for tree productivity and resilience, little is known about their seasonal regulations and trade-off with growth and reproduction. We characterize the seasonal dynamics of NSC in relation to the aboveground phenology and temporal growth patterns of three deciduous M...

journal_title：Scientific reports

authors： Tixier A,Guzmán-Delgado P,Sperling O,Amico Roxas A,Laca E,Zwieniecki MA

更新日期：2020-01-15 00:00:00

abstract：:Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD); however, more than 25% of COPD patients are non-smokers, and gene-by-smoking interactions are expected to affect COPD onset. We aimed to identify the common genetic variants interacting with pack-years of smoking on FEV1/FVC ratios in ind...

journal_title：Scientific reports

authors： Park B,An J,Kim W,Kang HY,Koh SB,Oh B,Jung KJ,Jee SH,Kim WJ,Cho MH,Silverman EK,Park T,Won S

更新日期：2020-08-04 00:00:00

abstract：:Podocyte injury has been suggested to induce phenotypic alteration of glomerular podocytes and accelerate the detachment of podocytes from the glomeruli resulting in podocyturia. However, it is not clear whether podocyte phenotypic alteration occurs in the urine of women with preeclampsia (PE). Seventy-seven and 116 p...

journal_title：Scientific reports

authors： Zhai T,Furuta I,Akaishi R,Ishikawa S,Morikawa M,Yamada T,Koyama T,Minakami H

更新日期：2016-04-07 00:00:00

abstract：:Interleukin-8 (IL-8) as an important cytokine involving in inflammatory and immune response, has been studied as effective adjuvants for vaccines in mammals. However, there are fewer reports about the characterization and adjuvant effects of IL-8 in fish. In this study, cloning and sequence analysis of IL-8 coding reg...

journal_title：Scientific reports

authors： Wang E,Wang J,Long B,Wang K,He Y,Yang Q,Chen D,Geng Y,Huang X,Ouyang P,Lai W

更新日期：2016-07-04 00:00:00

abstract：:Consecutive eight study phases under the successive presence and absence of UV irradiation, water vapor, and oxygen were conducted to characterize surface changes in the photocatalytic TiO2 powder using near-ambient-pressure X-ray photoelectron spectroscopy (XPS). Both Ti 2p and O 1s spectra show hysteresis through th...

journal_title：Scientific reports

authors： Krishnan P,Liu M,Itty PA,Liu Z,Rheinheimer V,Zhang MH,Monteiro PJ,Yu LE

更新日期：2017-02-27 00:00:00

abstract：:Previous work has shown that human vision performs spatial integration of luminance contrast energy, where signals are squared and summed (with internal noise) over area at detection threshold. We tested that model here in an experiment using arrays of micro-pattern textures that varied in overall stimulus area and sp...

journal_title：Scientific reports

authors： Baker DH,Meese TS

更新日期：2016-07-27 00:00:00

abstract：:Pterostilbene (PT), the natural dimethylated analog of resveratrol (RSV), is a potent anticarcinogen for non-small-cell lung cancer (NSCLC), but its anti-NSCLC mechanisms remain unclear. In this study, we show that PT treatment time- and dose-dependently enhanced the endoplasmic reticulum stress (ERS) signaling (i.e.,...

journal_title：Scientific reports

authors： Ma Z,Yang Y,Di S,Feng X,Liu D,Jiang S,Hu W,Qin Z,Li Y,Lv J,Fan C,Yan X,Li X

更新日期：2017-08-14 00:00:00

abstract：:Across the planet the biogeographic distribution of human cultural diversity tends to correlate positively with biodiversity. In this paper we focus on the biogeographic distribution of mammal species and human cultural diversity. We show that not only are these forms of diversity similarly distributed in space, but t...

journal_title：Scientific reports

authors： Hamilton MJ,Walker RS,Kempes CP

更新日期：2020-11-12 00:00:00

abstract：:Novelty seeking (NS) is a personality trait reflecting excitement in response to novel stimuli. High NS is usually a predictor of risky behaviour such as drug abuse. However, the relationships between NS and risk-related cognitive processes, including individual risk preference and the brain activation associated with...

journal_title：Scientific reports

authors： Wang Y,Liu Y,Yang L,Gu F,Li X,Zha R,Wei Z,Pei Y,Zhang P,Zhou Y,Zhang X

更新日期：2015-06-11 00:00:00

abstract：:Malaria has steadily increased in the Peruvian Amazon over the last five years. This study aimed to determine the parasite prevalence and micro-geographical heterogeneity of Plasmodium vivax parasitaemia in communities of the Peruvian Amazon. Four cross-sectional active case detection surveys were conducted between Ma...

journal_title：Scientific reports

authors： Carrasco-Escobar G,Gamboa D,Castro MC,Bangdiwala SI,Rodriguez H,Contreras-Mancilla J,Alava F,Speybroeck N,Lescano AG,Vinetz JM,Rosas-Aguirre A,Llanos-Cuentas A

更新日期：2017-08-14 00:00:00

abstract：:The systematics of Oriental freshwater mussels (Bivalvia: Unionidae) is poorly known. Here, we present an integrative revision of the genus Trapezoideus Simpson, 1900 to further understanding of freshwater mussel diversity in the region. We demonstrate that Trapezoideus as currently circumscribed is non-monophyletic, ...

journal_title：Scientific reports

authors： Konopleva ES,Pfeiffer JM,Vikhrev IV,Kondakov AV,Gofarov MY,Aksenova OV,Lunn Z,Chan N,Bolotov IN

更新日期：2019-03-11 00:00:00

abstract：:Due to their immunosuppressive properties, mesenchymal stem cells (MSC) have been evaluated for the treatment of immunological diseases. However, the animal-derived growth supplements utilized for MSC manufacturing may lead to clinical complications. Characterization of alternative media formulations is imperative for...

journal_title：Scientific reports

authors： Oikonomopoulos A,van Deen WK,Manansala AR,Lacey PN,Tomakili TA,Ziman A,Hommes DW

更新日期：2015-11-13 00:00:00

abstract：:Lytic transglycosylases (LTs) catalyze the non-hydrolytic cleavage of the bacterial cell wall by an intramolecular transacetalization reaction. This reaction is critically and broadly important in modifications of the bacterial cell wall in the course of its biosynthesis, recycling, manifestation of virulence, inserti...

journal_title：Scientific reports

authors： Byun B,Mahasenan KV,Dik DA,Marous DR,Speri E,Kumarasiri M,Fisher JF,Hermoso JA,Mobashery S

更新日期：2018-03-07 00:00:00

abstract：:Whey protein concentrate (WPC) is an amino acid-rich supplement that has been shown to increase cellular antioxidant capacity. Mammalian target of rapamycin (mTOR) is a crucial regulator of signaling in mammalian cells, and serves as a therapeutic target for triple-negative breast cancer (TNBC). This study was designe...

journal_title：Scientific reports

authors： Cheng SH,Tseng YM,Wu SH,Tsai SM,Tsai LY

更新日期：2017-11-21 00:00:00

abstract：:Due to the two dimensional confinement of electrons in a monolayer of 2D materials, the properties of monolayer can be controlled by electrical field formed on the monolayer surface. F4TCNQ was evaporated on MoS2 and WS2 monolayer forming dipoles between strong acceptor, F4TCNQ, and monolayers of MoS2 or WS2. The stro...

journal_title：Scientific reports

authors： Hu P,Ye J,He X,Du K,Zhang KK,Wang X,Xiong Q,Liu Z,Jiang H,Kloc C

更新日期：2016-04-07 00:00:00

abstract：:ANO1 is a calcium-activated chloride channel that is frequently overexpressed in head and neck squamous cell carcinoma (HNSCC) and other cancers. While ANO1 expression negatively correlates with survival in several cancers, its epigenetic regulation is poorly understood. We analyzed HNSCC samples from TCGA and a separ...

journal_title：Scientific reports

authors： Finegersh A,Kulich S,Guo T,Favorov AV,Fertig EJ,Danilova LV,Gaykalova DA,Califano JA,Duvvuri U

更新日期：2017-11-09 00:00:00

abstract：:Labeling nuclear proteins with electron dense probes in living cells has been a major challenge due to their inability to penetrate into nuclei. We developed a lipid-based approach for delivering antibodies coupled to 0.8 nm ultrasmall gold particles into the nucleus to label RNA polymerase II. Focussed Ion Beam slici...

journal_title：Scientific reports

authors： Orlov I,Schertel A,Zuber G,Klaholz B,Drillien R,Weiss E,Schultz P,Spehner D

更新日期：2015-02-09 00:00:00

abstract：:Oil spills represent an overwhelming carbon input to the marine environment that immediately impacts the sea surface ecosystem. Microbial communities degrading the oil fraction that eventually sinks to the seafloor must also deal with hydrostatic pressure, which linearly increases with depth. Piezosensitive hydrocarbo...

journal_title：Scientific reports

authors： Scoma A,Barbato M,Hernandez-Sanabria E,Mapelli F,Daffonchio D,Borin S,Boon N

更新日期：2016-03-29 00:00:00

abstract：:We compared coincidence-anticipation performance in normal vision and stroboscopic vision as a function of time-on-task. Participants estimated the arrival time of a real object that moved with constant acceleration (-0.7, 0, +0.7 m/s2) in a pseudo-randomised order across 4 blocks of 30 trials in both vision condition...

journal_title：Scientific reports

authors： Ballester R,Huertas F,Uji M,Bennett SJ

更新日期：2017-12-20 00:00:00

abstract：:Although various function of chemerin have been suggested, its physiological role remains to be elucidated. Here we show that chemerin-deficient mice are glucose intolerant irrespective of exhibiting reduced macrophage accumulation in adipose tissue. The glucose intolerance was mainly due to increased hepatic glucose ...

journal_title：Scientific reports

authors： Takahashi M,Okimura Y,Iguchi G,Nishizawa H,Yamamoto M,Suda K,Kitazawa R,Fujimoto W,Takahashi K,Zolotaryov FN,Hong KS,Kiyonari H,Abe T,Kaji H,Kitazawa S,Kasuga M,Chihara K,Takahashi Y

更新日期：2011-01-01 00:00:00

abstract：:Nitrogen fixation is essential for the synthesis of many important chemicals (e.g., fertilizers, explosives) and basic building blocks for all forms of life (e.g., nucleotides for DNA and RNA, amino acids for proteins). However, direct nitrogen fixation is challenging as nitrogen (N₂) does not easily react with other ...

journal_title：Scientific reports

authors： Jeon IY,Choi HJ,Ju MJ,Choi IT,Lim K,Ko J,Kim HK,Kim JC,Lee JJ,Shin D,Jung SM,Seo JM,Kim MJ,Park N,Dai L,Baek JB

更新日期：2013-01-01 00:00:00

abstract：:The static synchronous series compensator (SSSC) can add a series reactance to the transmission line, and when it is fed using auxiliary signals, it can participate in damping inter-area oscillations by changing the series reactance. In this paper, the effect of the SSSC on small-signal stability is investigated. The ...

journal_title：Scientific reports

authors： Naderipour A,Abdul-Malek Z,Ramachandaramurthy VK,Miveh MR,Moghaddam MJH,Guerrero JM

更新日期：2020-07-22 00:00:00