Abstract：
:Gibberellin (GA) is a key signal molecule inducing differentiation of tracheary elements, fibers, and xylogenesis. However the molecular mechanisms underlying the effect of GA on xylem elongation and secondary wall development in tree species remain to be determined. In this study, Betula platyphylla (birch) seeds were treated with 300 ppm GA₃ and/or 300 ppm paclobutrazol (PAC), seed germination was recorded, and transverse sections of hypocotyls were stained with toluidine blue; the two-month-old seedlings were treated with 50 μM GA₃ and/or 50 μM PAC, transverse sections of seedling stems were stained using phloroglucinol-HCl, and secondary wall biosynthesis related genes expression was analyzed by real-time quantitative PCR. Results indicated that germination percentage, energy and time of seeds, hypocotyl height and seedling fresh weight were enhanced by GA₃, and reduced by PAC; the xylem development was wider in GA₃-treated plants than in the control; the expression of NAC and MYB transcription factors, CESA, PAL, and GA oxidase was up-regulated during GA₃ treatment, suggesting their role in GA₃-induced xylem development in the birch. Our results suggest that GA₃ induces the expression of secondary wall biosynthesis related genes to trigger xylogenesis in the birch plants.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Guo H,Wang Y,Liu H,Hu P,Jia Y,Zhang C,Wang Y,Gu S,Yang C,Wang Cdoi
10.3390/ijms160922960subject
Has Abstractpub_date
2015-09-23 00:00:00pages
22960-75issue
9issn
1422-0067pii
ijms160922960journal_volume
16pub_type
杂志文章abstract：:Heart failure (HF) is a rapidly growing global public health problem. Since HF results in high mortality and re-hospitalization, new effective treatments are desired. Although it remains controversial, omega 3 polyunsaturated fatty acids (n-3 PUFAs), such as the eicosapentaenoic acid and docosahexaenoic acid, have bee...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms20164025
更新日期：2019-08-18 00:00:00
abstract：:Increasing evidence has shown that many chronic diseases originate from early life, even before birth, through what are termed as fetal programming effects. Glucocorticoids are frequently used prenatally to accelerate the maturation of the lungs of premature infants. High-fat diets are associated with insulin resistan...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms17040533
更新日期：2016-04-08 00:00:00
abstract：:Articular cartilage is a structure lack of vascular distribution. Once the cartilage is injured or diseased, it is unable to regenerate by itself. Surgical treatments do not effectively heal defects in articular cartilage. Tissue engineering is the most potential solution to this problem. In this study, methoxy poly(e...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19041125
更新日期：2018-04-09 00:00:00
abstract：:Hypoxia is a common environmental stress factor and is associated with fibrogenesis. Matrix metalloproteinase-2 (MMP-2), produced by hepatic stellate cells (HSCs), plays an important role in liver fibrogenesis. However, inconsistent results have been reported on the impact of hypoxia on MMP-2 expression and activity i...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms12042434
更新日期：2011-01-01 00:00:00
abstract：:The immune system and the central nervous system message each other to preserving central homeostasis. Both systems undergo changes during aging that determine central age-related defects. Ellagic acid (EA) is a natural product which is beneficial in both peripheral and central diseases, including aging. We analyzed t...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21103631
更新日期：2020-05-21 00:00:00
abstract：:Microbes have co-evolved with human beings for millions of years. They play a very important role in maintaining the health of the host. With the advancement in next generation sequencing technology, the microbiome profiling in the host can be obtained under different circumstances. This review focuses on the current ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms161125957
更新日期：2015-11-03 00:00:00
abstract：:Manganese oxidizing bacteria can produce biogenic manganese oxides (BMO) on their cell surface and have been applied in the fields of agriculture, bioremediation, and drinking water treatment to remove toxic contaminants based on their remarkable chemical reactivity. Herein, we report for the first time the synthetic ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21051709
更新日期：2020-03-02 00:00:00
abstract：:The aim of this study was to determine the effect and mechanism of tamoxifen (TAM)-induced steatosis in vitro. HepG 2 (Human hepatocellular liver carcinoma cell line) cells were treated with different concentrations of TAM for 72 h. Steatosis of hepatocytes was determined after Oil Red O staining and measurement of tr...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms15034019
更新日期：2014-03-05 00:00:00
abstract：:Chronic hepatitis C is a serious liver disease that often results in cirrhosis or hepatocellular carcinoma. The aim of this study was to assess the association of human leukocyte antigen-DP (HLA-DP) variants with risk of chronic hepatitis C virus (HCV) or anti-F antibody generation. We selected two single nucleotide p...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms15069826
更新日期：2014-06-03 00:00:00
abstract：:The MAP kinase ERK5 contains an N-terminal kinase domain and a unique C-terminal tail including a nuclear localization signal and a transcriptional activation domain. ERK5 is activated in response to growth factors and stresses and regulates transcription at the nucleus by either phosphorylation or interaction with tr...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21062203
更新日期：2020-03-23 00:00:00
abstract：:Autophagy primarily works to counteract nutrient deprivation that is strongly engaged during starvation and hypoxia, which happens in hypoperfusion. Nonetheless, autophagy is slightly active even in baseline conditions, when it is useful to remove aged proteins and organelles. This is critical when the mitochondria an...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms19092756
更新日期：2018-09-13 00:00:00
abstract：:Nowadays, it is well accepted that inflammation is a critical player in cancer, being, in most cases, the main character of the process. Different types of tumor arise from sites of infection or chronic inflammation. This non-resolving inflammation is responsible for tumor development at different levels: it promotes ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms22031224
更新日期：2021-01-27 00:00:00
abstract：:The human gastrointestinal tract is inhabited by many types of microbiota, including bacteria, viruses, and fungi. Dysregulations of their microenvironment are associated with various health problems, not only limited to gastrointestinal disorders, such as inflammatory bowel disease, but to impacts beyond the intestin...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms20020387
更新日期：2019-01-17 00:00:00
abstract：:Psm ES4326/AvrRpt2 (AvrRpt2) was widely used as the reaction system of hypersensitive response (HR) in Arabidopsis. The study showed that in npr1 (GFP-ATG8a), AvrRpt2 was more effective at inducing the production of autophagosome and autophagy flux than that in GFP-ATG8a. The mRNA expression of ATG1, ATG6 and ATG8a we...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21145147
更新日期：2020-07-21 00:00:00
abstract：:To learn more about the structure-activity relationships of (E)-3-(5-styryl-1,3,4-oxadiazol-2-yl)benzenesulfonamide derivatives, which in our previous research displayed promising in vitro anticancer activity, we have synthesized a group of novel (E)-5-[(5-(2-arylvinyl)-1,3,4-oxadiazol-2-yl)]-4-chloro-2-R1-benzenesulf...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21062235
更新日期：2020-03-23 00:00:00
abstract：:Over the last few decades, the use of molecular markers has played an increasing role in rice breeding and genetics. Of the different types of molecular markers, microsatellites have been utilized most extensively, because they can be readily amplified by PCR and the large amount of allelic variation at each locus. Mi...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms141122499
更新日期：2013-11-14 00:00:00
abstract：:Adenosine triphosphate (ATP) has been well established as an important extracellular ligand of autocrine signaling, intercellular communication, and neurotransmission with numerous physiological and pathophysiological roles. In addition to the classical exocytosis, non-vesicular mechanisms of cellular ATP release have...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms19030808
更新日期：2018-03-11 00:00:00
abstract：:It is widely recognized that many chronic infections of the human body have a polymicrobial etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis patients, periodontitis, otitis, urinary tract infections and even a proportion of systemic infections. The treatment of mixed infection...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms22020482
更新日期：2021-01-06 00:00:00
abstract：:Cationic polymeric nanoparticles (NPs) have the ability to overcome biological membranes, leading to improved efficacy of anticancer drugs. The modulation of the particle-cell interaction is desired to control this effect and avoid toxicity to normal cells. In this study, we explored the surface functionalization of c...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20092350
更新日期：2019-05-11 00:00:00
abstract：:Diabetic kidney disease (DKD) remains the leading cause of end-stage renal disease (ESRD) and is therefore a major burden on the healthcare system. Patients with DKD are highly susceptible to developing cardiovascular disease, which contributes to increased morbidity and mortality rates. While progress has been made t...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms20143393
更新日期：2019-07-10 00:00:00
abstract：:Naturally existing Chlorogenic acid (CGA) is an antioxidant-rich compound reported to act a chemopreventive agent by scavenging free radicals and suppressing cancer-causing mechanisms. Conversely, the compound's poor thermal and pH (neutral and basic) stability, poor solubility, and low cellular permeability have been...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20194667
更新日期：2019-09-20 00:00:00
abstract：:The domain of unknown function 26 (DUF26), harboring a conserved cysteine-rich motif (C-X8-C-X2-C), is unique to land plants. Several cysteine-rich repeat proteins (CRRs), belonging to DUF26-containing proteins, have been implicated in the defense against fungal pathogens in ginkgo, cotton, and maize. However, little ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21165698
更新日期：2020-08-09 00:00:00
abstract：:Hemostasis disorder in patients with end-stage renal disease (ESRD) is frequently associated with bleeding diathesis but it may also manifest in thrombotic complications. Analysis of individual coagulation and fibrinolytic factors may shed light on the background of this paradox situation. Here we explored components ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21228426
更新日期：2020-11-10 00:00:00
abstract：:Triazophos is a widely used organophosphorous insecticide that has potentially adverse effects to organisms. In the present study, a high-affinity single-chain variable fragment (scFv) antibody with specific lambda light chain was developed for residue monitoring. First, the specific variable regions were correctly am...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms17060823
更新日期：2016-06-07 00:00:00
abstract：:The Mexican axolotl salamander (Ambystoma mexicanum) is one member of a select group of vertebrate animals that have retained the amazing ability to regenerate multiple body parts. In addition to being an important model system for regeneration, the axolotl has also contributed extensively to studies of basic developm...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms160922046
更新日期：2015-09-11 00:00:00
abstract：:Cadmium (Cd) is an anthropogenic as well as a naturally occurring toxicant associated with prediabetes and T2DM in humans and experimental models of Cd exposure. However, relatively few studies have examined the mechanism(s) of Cd-induced hyperglycemia. The purpose of this study was to examine the role of pancreatic i...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms22010360
更新日期：2020-12-31 00:00:00
abstract：:The FLOWERING LOCUS T (FT) gene plays crucial roles in regulating the transition from the vegetative to reproductive phase. To understand the molecular mechanism of reproduction, three homologous FT genes were isolated and characterized from Cymbidium sinense "Qi Jian Bai Mo", Cymbidium goeringii and Cymbidium ensifol...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms130911385
更新日期：2012-01-01 00:00:00
abstract：:Hybrid materials constituted by peptides and synthetic polymers have nowadays a great interest since they can combine the properties and functions of each constitutive block, being also possible to modify the final characteristics by using different topologies. Poly(l-lactide-b-l-phenylalanine) copolymers with various...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms150813247
更新日期：2014-07-29 00:00:00
abstract：:A complex antioxidant system has been developed in mammals to relieve oxidative stress. However, excessive reactive species derived from oxygen and nitrogen may still lead to oxidative damage to tissue and organs. Oxidative stress has been considered as a conjoint pathological mechanism, and it contributes to initiati...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms161125942
更新日期：2015-11-02 00:00:00
abstract：:The activation of extracellular signal-regulated kinases (ERK) leads to a number of cellular changes associated with the development of long-term memory. Using cultured cortical neurons, we previously showed that the n-hexane extract prepared from the peels of Citrus grandis (Kawachi bankan) induces the activation of ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms13055338
更新日期：2012-01-01 00:00:00
