Abstract：
INTRODUCTION:Application of mechanical ventilation in spontaneously breathing children remains a challenge for several reasons: mainly, small tidal volumes and high respiratory rates, especially in the presence of leaks, interfere with patient-ventilator synchrony. Leaks also cause unreliable monitoring of respiratory drive and respiratory rate. Furthermore, ventilator adjustment must take into account that infants have strong vagal reflexes, demonstrate central apnea and periodic breathing, with a high variability in breathing pattern. Neurally-adjusted ventilatory assist (NAVA) is a mode of ventilation whereby the timing and amount of ventilatory assist is controlled by the patient's neural respiratory drive. Since NAVA uses the diaphragm electrical activity (Edi) as the controller signal, it is possible to deliver synchronized assist, both invasively and non-invasively (NIV-NAVA), to follow the variability in breathing pattern, and to monitor patient respiratory drive, independent of leaks. EVIDENCE ACQUISITION:This article provides a review of the scientific literature pertaining to the use of NAVA in children (neonatal and pediatric age groups). Both the invasive and non-invasive NAVA publications are summarized, as well as the use of Edi monitoring. EVIDENCE SYNTHESIS:Overall, the use of NAVA and Edi monitoring is feasible and safe. Compared to conventional ventilation, NAVA improves patient-ventilator interaction, and provides lower peak inspiratory pressure. CONCLUSIONS:Evidence from a few trials suggests improved comfort, less sedation, and reduced length of stay.
journal_name
Minerva Anestesioljournal_title
Minerva anestesiologicaauthors
Beck J,Emeriaud G,Liu Y,Sinderby Csubject
Has Abstractpub_date
2016-08-01 00:00:00pages
874-83issue
8eissn
0375-9393issn
1827-1596pii
R02Y9999N00A150116journal_volume
82pub_type
杂志文章,评审abstract：:The selection of opioid drugs for anesthesia is often based on empirical judgment such as the selection of opioids with rapid elimination half-life for short surgical procedures (e.g. alfentanil), while opioids with longer elimination half-life (e.g. fentanyl, sufentanil) are used for longer procedures. A better insig...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
abstract：:Peer review is the process by which manuscripts submitted to medical journals are evaluated for scientific soundness and priority, and potentially improved in terms of clarity. Constructive interaction between editors, reviewers, and authors is critical for the effectiveness of the entire process. Although empirical e...
journal_title：Minerva anestesiologica
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doi：
更新日期：2009-10-01 00:00:00
abstract：:Accidents during anaesthesia may be clinical or technical. To avoid the latter, stress is laid on the by no means new concept that techniques and handling must fit contingent requirements and that they may be dangerous as much for their inadequate as for their excessive use. ...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Cannabinoids appear to possess many potential medical uses, which may extend to pain control. A narrative review of the literature has found a variety of studies testing botanical and synthetic cannabinoids in different pain syndromes (acute pain, cancer pain, chronic noncancer pain, fibromyalgia pain, migraine, neuro...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：10.23736/S0375-9393.18.12287-5
更新日期：2018-08-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2003-10-01 00:00:00
abstract：BACKGROUND:Sudden cardiac arrest is one of the leading causes of death in Europe and the whole world. Effective chest compressions and advanced airway management have been shown to improve survival rates. Supraglottic airway devices such as the laryngeal tube (LT) are a well-known strategy for patients with cardiac arr...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：10.23736/S0375-9393.20.14446-8
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abstract：BACKGROUND:Few studies have investigated the incidence of pulmonary anaerobes in a specific population in surgical Intensive Care Unit (ICU). The objective of this work was to determine the incidence of anaerobes in surgical ICU patients with suspected pneumonia. METHODS:This was a prospective observational, single-ce...
journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2014-10-01 00:00:00
abstract：:Nutrition in critically ill patients should be considered as therapy: assessing the energy expenditure and the termogenic effect of food, and knowing the differences among composition and amount of given substrates, it is possible restore, maintain, or at least limit the derangement of energy equilibrium. Energy metab...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-06-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-10-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2010-04-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:The aim of the study was to investigate whether or not sevoflurane at different concentrations influenced the ED(effective dose) 50, 90 and 95 of cisatracurium and whether there is any relationship with age. METHODS:Individual dose response curves for cisatracurium were constructed in 80 consecutive patient...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:The characteristics of sevoflurane make it able to be used without N2O avoiding its undesirable effects to this associates. The aim of the study is to evaluate the clinical characteristics of sevoflurane anesthesia "N2O free" in comparison to sevoflurane anesthesia with N2O. METHODS:920 patient undergoing e...
journal_title：Minerva anestesiologica
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2000-09-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1992-04-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Anaesthesia with atracurium, fentanyl, and continuous intravenous infusion of propofol in two myasthenic patients is described. There were no intra and postoperative problems and operative conditions were considered excellent. This technique offers a safe alternative to inhalational anaesthesia for patients with myast...
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1992-03-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2004-04-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Non invasive ventilation (NIV) has been shown to be an effective therapy in selected patients with acute respiratory failure. Due to its benefit and relative ease of use, NIV is frequently used. In addition, the shortage and high cost of intensive care beds have prompted the use of NIV outside the intensive care unit....
journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2009-07-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2004-04-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2005-09-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
更新日期：2012-06-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2005-06-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：1998-05-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2008-06-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2015-10-01 00:00:00
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journal_title：Minerva anestesiologica
pub_type： 杂志文章
doi：
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journal_title：Minerva anestesiologica
pub_type： 杂志文章,评审
doi：
更新日期：2012-09-01 00:00:00
