Nano-socketed nickel particles with enhanced coking resistance grown in situ by redox exsolution.

abstract：:A number of modes of oscillations of particles and fields can exist in space plasmas. Since the early 1970s, space missions have observed noise-like plasma waves near the geomagnetic equator known as 'equatorial noise'. Several theories were suggested, but clear observational evidence supported by realistic modelling ...

journal_title：Nature communications

authors： Balikhin MA,Shprits YY,Walker SN,Chen L,Cornilleau-Wehrlin N,Dandouras I,Santolik O,Carr C,Yearby KH,Weiss B

更新日期：2015-07-14 00:00:00

abstract：:Oscillatory synchrony among neurons occurs in many species and brain areas, and has been proposed to help neural circuits process information. One hypothesis states that oscillatory input creates cyclic integration windows: specific times in each oscillatory cycle when postsynaptic neurons become especially responsive...

journal_title：Nature communications

authors： Gupta N,Singh SS,Stopfer M

更新日期：2016-12-15 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is characterized by muscle degeneration and progressive weakness. There is considerable inter-patient variability in disease onset and progression, which can confound the results of clinical trials. Here we show that a common null polymorphism (R577X) in ACTN3 results in significantly...

journal_title：Nature communications

authors： Hogarth MW,Houweling PJ,Thomas KC,Gordish-Dressman H,Bello L,Cooperative International Neuromuscular Research Group (CINRG).,Pegoraro E,Hoffman EP,Head SI,North KN

更新日期：2017-01-31 00:00:00

abstract：:The exceptional interest in improving the limitations of data storage, molecular electronics and optoelectronics has promoted the development of an ever increasing number of techniques used to pattern polymers at micro and nanoscale. Most of them rely on atomic force microscopy to thermally or electrostatically induce...

journal_title：Nature communications

authors： Farina M,Ye T,Lanzani G,di Donato A,Venanzoni G,Mencarelli D,Pietrangelo T,Morini A,Keivanidis PE

更新日期：2013-01-01 00:00:00

abstract：:Artemisinin and its derivatives (collectively referred to as ARTs) rapidly reduce the parasite burden in Plasmodium falciparum infections, and antimalarial control is highly dependent on ART combination therapies (ACTs). Decreased sensitivity to ARTs is emerging, making it critically important to understand the mechan...

journal_title：Nature communications

authors： Bridgford JL,Xie SC,Cobbold SA,Pasaje CFA,Herrmann S,Yang T,Gillett DL,Dick LR,Ralph SA,Dogovski C,Spillman NJ,Tilley L

更新日期：2018-09-18 00:00:00

abstract：:In chronic lymphocytic leukemia (CLL), the non-hematopoietic stromal microenvironment plays a critical role in promoting tumor cell recruitment, activation, survival, and expansion. However, the nature of the stromal cells and molecular pathways involved remain largely unknown. Here, we demonstrate that leukemic B lym...

journal_title：Nature communications

authors： Farinello D,Wozińska M,Lenti E,Genovese L,Bianchessi S,Migliori E,Sacchetti N,di Lillo A,Bertilaccio MTS,de Lalla C,Valsecchi R,Gleave SB,Lligé D,Scielzo C,Mauri L,Ciampa MG,Scarfò L,Bernardi R,Lazarevic D,Gonzalez-

更新日期：2018-05-03 00:00:00

abstract：:Although kidney parenchymal tissue can be generated in vitro, reconstructing the complex vasculature of the kidney remains a daunting task. The molecular pathways that specify and sustain functional, phenotypic and structural heterogeneity of the kidney vasculature are unknown. Here, we employ high-throughput bulk and...

journal_title：Nature communications

authors： Barry DM,McMillan EA,Kunar B,Lis R,Zhang T,Lu T,Daniel E,Yokoyama M,Gomez-Salinero JM,Sureshbabu A,Cleaver O,Di Lorenzo A,Choi ME,Xiang J,Redmond D,Rabbany SY,Muthukumar T,Rafii S

更新日期：2019-12-13 00:00:00

abstract：:High-grade serous ovarian cancers (HGSOC) have been subdivided into molecular subtypes. The mesenchymal HGSOC subgroup, defined by stromal-related gene signatures, is invariably associated with poor patient survival. We demonstrate that stroma exerts a key function in mesenchymal HGSOC. We highlight stromal heterogene...

journal_title：Nature communications

authors： Givel AM,Kieffer Y,Scholer-Dahirel A,Sirven P,Cardon M,Pelon F,Magagna I,Gentric G,Costa A,Bonneau C,Mieulet V,Vincent-Salomon A,Mechta-Grigoriou F

更新日期：2018-03-13 00:00:00

abstract：:14-3-3 family proteins regulate multiple signalling pathways. Understanding biological functions of 14-3-3 proteins has been limited by the functional redundancy of conserved isotypes. Here we provide evidence that 14-3-3 proteins regulate two interacting components of Tor signalling in Drosophila, translationally con...

journal_title：Nature communications

authors： Le TP,Vuong LT,Kim AR,Hsu YC,Choi KW

更新日期：2016-05-06 00:00:00

abstract：:Mammalian and Drosophila genomes are partitioned into topologically associating domains (TADs). Although this partitioning has been reported to be functionally relevant, it is unclear whether TADs represent true physical units located at the same genomic positions in each cell nucleus or emerge as an average of numero...

journal_title：Nature communications

authors： Ulianov SV,Zakharova VV,Galitsyna AA,Kos PI,Polovnikov KE,Flyamer IM,Mikhaleva EA,Khrameeva EE,Germini D,Logacheva MD,Gavrilov AA,Gorsky AS,Nechaev SK,Gelfand MS,Vassetzky YS,Chertovich AV,Shevelyov YY,Razin SV

更新日期：2021-01-04 00:00:00

abstract：:Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regulate vessel growth. ...

journal_title：Nature communications

authors： Mouillesseaux KP,Wiley DS,Saunders LM,Wylie LA,Kushner EJ,Chong DC,Citrin KM,Barber AT,Park Y,Kim JD,Samsa LA,Kim J,Liu J,Jin SW,Bautch VL

更新日期：2016-11-11 00:00:00

abstract：:Activation of the NLRP3 inflammasome and subsequent maturation of IL-1β have been implicated in acute lung injury (ALI), resulting in inflammation and fibrosis. We investigated the role of vimentin, a type III intermediate filament, in this process using three well-characterized murine models of ALI known to require N...

journal_title：Nature communications

authors： dos Santos G,Rogel MR,Baker MA,Troken JR,Urich D,Morales-Nebreda L,Sennello JA,Kutuzov MA,Sitikov A,Davis JM,Lam AP,Cheresh P,Kamp D,Shumaker DK,Budinger GR,Ridge KM

更新日期：2015-03-12 00:00:00

abstract：:The three-dimensional architecture of the genome affects genomic functions. Multiple genome architectures at different length scales, including chromatin loops, domains, compartments, and lamina- and nucleolus-associated regions, have been discovered. However, how these structures are arranged in the same cell and how...

journal_title：Nature communications

authors： Liu M,Lu Y,Yang B,Chen Y,Radda JSD,Hu M,Katz SG,Wang S

更新日期：2020-06-09 00:00:00

abstract：:Phospholipids are elemental building-block molecules for biological membranes. Biosynthesis of phosphatidylinositol, phosphatidylglycerol and phosphatidylserine requires a central liponucleotide intermediate named cytidine-diphosphate diacylglycerol (CDP-DAG). The CDP-DAG synthetase (Cds) is an integral membrane enzym...

journal_title：Nature communications

authors： Liu X,Yin Y,Wu J,Liu Z

更新日期：2014-06-27 00:00:00

abstract：:The bio-integrated electronics industry is booming and becoming more integrated with biological tissues. To successfully integrate with the soft tissues of the body (eg. skin), the material must possess many of the same properties including compliance, toughness, elasticity, and tear resistance. In this work, we prepa...

journal_title：Nature communications

authors： Chen S,Sun L,Zhou X,Guo Y,Song J,Qian S,Liu Z,Guan Q,Meade Jeffries E,Liu W,Wang Y,He C,You Z

更新日期：2020-02-27 00:00:00

abstract：:The two-dimensional topological insulators host a full gap in the bulk band, induced by spin-orbit coupling (SOC) effect, together with the topologically protected gapless edge states. However, it is usually challenging to suppress the bulk conductance and thus to realize the quantum spin Hall (QSH) effect. In this st...

journal_title：Nature communications

authors： Song YH,Jia ZY,Zhang D,Zhu XY,Shi ZQ,Wang H,Zhu L,Yuan QQ,Zhang H,Xing DY,Li SC

更新日期：2018-10-04 00:00:00

abstract：:The caudal-related homeobox transcription factor CDX2 is expressed in leukemic cells but not during normal blood formation. Retroviral overexpression of Cdx2 induces AML in mice, however the developmental stage at which CDX2 exerts its effect is unknown. We developed a conditionally inducible Cdx2 mouse model to deter...

journal_title：Nature communications

authors： Vu T,Straube J,Porter AH,Bywater M,Song A,Ling V,Cooper L,Pali G,Bruedigam C,Jacquelin S,Green J,Magor G,Perkins A,Chalk AM,Walkley CR,Heidel FH,Mukhopadhyay P,Cloonan N,Gröschel S,Mallm JP,Fröhling S,Scholl C,

更新日期：2020-06-15 00:00:00

abstract：:Application of force on biomolecules has been instrumental in understanding biofunctional behaviour from single molecules to complex collections of cells. Current approaches, for example, those based on atomic force microscopy or magnetic or optical tweezers, are powerful but limited in their applicability as integrat...

journal_title：Nature communications

authors： Webster A,Vollmer F,Sato Y

更新日期：2014-10-21 00:00:00

abstract：:Planar neural networks and interfaces serve as versatile in vitro models of central nervous system physiology, but adaptations of related methods to three dimensions (3D) have met with limited success. Here, we demonstrate for the first time volumetric functional imaging in a bioengineered neural tissue growing in a t...

journal_title：Nature communications

authors： Dana H,Marom A,Paluch S,Dvorkin R,Brosh I,Shoham S

更新日期：2014-06-05 00:00:00

abstract：:Inspired by mammalian skins, soft hybrids integrating the merits of elastomers and hydrogels have potential applications in diverse areas including stretchable and bio-integrated electronics, microfluidics, tissue engineering, soft robotics and biomedical devices. However, existing hydrogel-elastomer hybrids have limi...

journal_title：Nature communications

authors： Yuk H,Zhang T,Parada GA,Liu X,Zhao X

更新日期：2016-06-27 00:00:00

abstract：:Express delivery services are booming in both developed and emerging economies due to their low cost, convenience, and the fast growth in online shopping. The increasing environmental impacts of express delivery services and mitigation potentials, however, remain largely unexplored. Here we addressed such a gap for Ch...

journal_title：Nature communications

authors： Kang P,Song G,Xu M,Miller TR,Wang H,Zhang H,Liu G,Zhou Y,Ren J,Zhong R,Duan H

更新日期：2021-01-19 00:00:00

abstract：:Earth's core is composed of iron (Fe) alloyed with light elements, e.g., silicon (Si). Its thermal conductivity critically affects Earth's thermal structure, evolution, and dynamics, as it controls the magnitude of thermal and compositional sources required to sustain a geodynamo over Earth's history. Here we directly...

journal_title：Nature communications

authors： Hsieh WP,Goncharov AF,Labrosse S,Holtgrewe N,Lobanov SS,Chuvashova I,Deschamps F,Lin JF

更新日期：2020-07-03 00:00:00

abstract：:Liposarcomas (LPSs) are a group of malignant mesenchymal tumors showing adipocytic differentiation. Here, to gain insight into the enhancer dysregulation and transcriptional addiction in this disease, we chart super-enhancer structures in both LPS tissues and cell lines. We identify a bromodomain and extraterminal (BE...

journal_title：Nature communications

authors： Chen Y,Xu L,Mayakonda A,Huang ML,Kanojia D,Tan TZ,Dakle P,Lin RY,Ke XY,Said JW,Chen J,Gery S,Ding LW,Jiang YY,Pang A,Puhaindran ME,Goh BC,Koeffler HP

更新日期：2019-03-22 00:00:00

abstract：:Linking microbial metabolomics and carbon sequestration in the ocean via refractory organic molecules has been hampered by the chemical complexity of dissolved organic matter (DOM). Here, using bioassay experiments and ultra-high resolution metabolic profiling, we demonstrate that marine bacteria rapidly utilize simpl...

journal_title：Nature communications

authors： Lechtenfeld OJ,Hertkorn N,Shen Y,Witt M,Benner R

更新日期：2015-03-31 00:00:00

abstract：:Intentional doping is the core of semiconductor technologies to tune electrical and optical properties of semiconductors for electronic devices, however, it has shown to be a grand challenge for halide perovskites. Here, we show that some metal ions, such as silver, strontium, cerium ions, which exist in the precursor...

journal_title：Nature communications

authors： Lin Y,Shao Y,Dai J,Li T,Liu Y,Dai X,Xiao X,Deng Y,Gruverman A,Zeng XC,Huang J

更新日期：2021-01-04 00:00:00

abstract：:The development of stimulus-responsive polymeric materials is of great importance, especially for the development of remotely manipulated materials not in direct contact with an actuator. Here we design a photoresponsive supramolecular actuator by integrating host-guest interactions and photoswitching ability in a hyd...

journal_title：Nature communications

authors： Takashima Y,Hatanaka S,Otsubo M,Nakahata M,Kakuta T,Hashidzume A,Yamaguchi H,Harada A

更新日期：2012-01-01 00:00:00

abstract：:Non-CG methylation has been associated with stemness regulation in embryonic stem cells. By comparing differentially expressed genes affected by non-CG methylation between tumour and corresponding non-tumour tissues in oesophageal squamous cell carcinoma (OSCC), we find that Integrin α7 (ITGA7) is characterized as a p...

journal_title：Nature communications

authors： Ming XY,Fu L,Zhang LY,Qin YR,Cao TT,Chan KW,Ma S,Xie D,Guan XY

更新日期：2016-12-07 00:00:00

abstract：:Oceanic mesoscale eddies contribute important horizontal heat and salt transports on a global scale. Here we show that eddy transports are mainly due to individual eddy movements. Theoretical and observational analyses indicate that cyclonic and anticyclonic eddies move westwards, and they also move polewards and equa...

journal_title：Nature communications

authors： Dong C,McWilliams JC,Liu Y,Chen D

更新日期：2014-01-01 00:00:00

abstract：:Little is known about how archaeal viruses perturb the transcription machinery of their hosts. Here we provide the first example of an archaeo-viral transcription factor that directly targets the host RNA polymerase (RNAP) and efficiently represses its activity. ORF145 from the temperate Acidianus two-tailed virus (AT...

journal_title：Nature communications

authors： Sheppard C,Blombach F,Belsom A,Schulz S,Daviter T,Smollett K,Mahieu E,Erdmann S,Tinnefeld P,Garrett R,Grohmann D,Rappsilber J,Werner F

更新日期：2016-11-24 00:00:00

abstract：:In humans, mutations in the PIEZO2 gene, which encodes for a mechanosensitive ion channel, were found to result in skeletal abnormalities including scoliosis and hip dysplasia. Here, we show in mice that loss of Piezo2 expression in the proprioceptive system recapitulates several human skeletal abnormalities. While lo...

journal_title：Nature communications

authors： Assaraf E,Blecher R,Heinemann-Yerushalmi L,Krief S,Carmel Vinestock R,Biton IE,Brumfeld V,Rotkopf R,Avisar E,Agar G,Zelzer E

更新日期：2020-06-23 00:00:00