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Neurosarcoidosis as an MS Mimic: The trials and tribulations of making a diagnosis.

Abstract：

:The clinical presentation of neurosarcoidosis is varied as multiple levels of the neuraxis may be affected. When central nervous system involvement occurs, making an accurate diagnosis of the condition can be challenging, especially given the current definition for definite neurosarcoidosis requires histologic confirmation of the affected tissue (brain biopsy). This article will review our current knowledge and manifestations of neurosarcoidosis, discuss the current diagnostic approach as well as the challenges associated with a condition requiring histologic confirmation, discuss the current treatment approach, and highlight the challenges of this diagnosis with a few real-life clinical cases. We also highlight the selected differential diagnosis of neurosarcoidosis as well as multiple sclerosis which could mimic each other.

journal_name

Mult Scler Relat Disord

journal_title

Multiple sclerosis and related disorders

authors

MacLean HJ,Abdoli M

doi

10.1016/j.msard.2015.06.012

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

414-429

issue

5

eissn

2211-0348

issn

2211-0356

pii

S2211-0348(15)00083-8

journal_volume

4

pub_type

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