Abstract：
OBJECTIVES:To examine the association between vagotomy and multiple sclerosis. METHODS:We conducted a matched cohort study of all patients who underwent truncal or super-selective vagotomy and a comparison cohort, by linking Danish population-based medical registries (1977-1995). Hazard ratios (HRs) for multiple sclerosis, adjusting for potential confounders were computed by means of Cox regression analysis. RESULTS:Median age of multiple sclerosis onset corresponded to late onset multiple sclerosis. No association with multiple sclerosis was observed for truncal vagotomy (0-37 year adjusted HR=0.91, 95% confidence interval [CI]: 0.48-1.74) or super-selective vagotomy (0-37 year adjusted HR=1.28, 95% CI: 0.79-2.09) compared with the general population. INTERPRETATION:We found no association between vagotomy and later risk of late onset multiple sclerosis.
journal_name
Mult Scler Relat Disordjournal_title
Multiple sclerosis and related disordersauthors
Sundbøll J,Horváth-Puhó E,Adelborg K,Svensson Edoi
10.1016/j.msard.2017.04.009subject
Has Abstractpub_date
2017-07-01 00:00:00pages
34-36eissn
2211-0348issn
2211-0356pii
S2211-0348(17)30079-2journal_volume
15pub_type
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journal_title：Multiple sclerosis and related disorders
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journal_title：Multiple sclerosis and related disorders
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章,多中心研究
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journal_title：Multiple sclerosis and related disorders
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journal_title：Multiple sclerosis and related disorders
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2020.102478
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2020.102190
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journal_title：Multiple sclerosis and related disorders
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2019.05.013
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2016.05.009
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2015.07.009
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Multiple Sclerosis (MS) pathology is likely to disrupt central auditory pathways, thereby affecting an individual's ability to discriminate speech from noise. Despite the importance of speech discrimination in daily communication, it's characterization in the context of MS remains limited. This cross-section...
journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2020.102608
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Prediction of the course of multiple sclerosis (MS) was traditionally based on features close to onset. OBJECTIVE:To evaluate predictors of the individual risk of secondary progression (SP) identified at any time during relapsing-remitting MS. METHODS:We analysed a database comprising an untreated MS incid...
journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2014.04.004
更新日期：2014-09-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2020.102334
更新日期：2020-10-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章,评审
doi：10.1016/j.msard.2019.04.003
更新日期：2019-07-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2019.01.031
更新日期：2019-04-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2019.101402
更新日期：2019-11-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2018.10.003
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2019.04.030
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journal_title：Multiple sclerosis and related disorders
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doi：10.1016/j.msard.2014.09.211
更新日期：2015-01-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2020.102382
更新日期：2020-10-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2017.02.015
更新日期：2017-04-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2020.102607
更新日期：2020-10-31 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2018.07.002
更新日期：2018-08-01 00:00:00
abstract：:Currently, there are no approved treatments for NMO. All therapeutic studies in NMO have been either small, retrospective case series or uncontrolled prospective studies. Such studies are susceptible to inherent biases. As a consequence, conclusions regarding efficacy and safety from these studies may be erroneous. Th...
journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章,评审
doi：10.1016/j.msard.2015.07.017
更新日期：2015-11-01 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
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更新日期：2021-01-17 00:00:00
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journal_title：Multiple sclerosis and related disorders
pub_type：
doi：10.1016/j.msard.2020.102120
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Previous studies suggest the existence of a prodromal period in multiple sclerosis, but little is known about the phenotypic characteristics. This study aims to characterize the multiple sclerosis (MS) prodrome using data mining analytics in the healthcare setting. METHODS:We identified people with MS and m...
journal_title：Multiple sclerosis and related disorders
pub_type： 杂志文章
doi：10.1016/j.msard.2018.08.007
更新日期：2018-10-01 00:00:00
