Comprehensive analyses of genomes, transcriptomes and metabolites of neem tree.

abstract：BACKGROUND:In Burkina Faso, it is not uncommon for mothers to drink alcohol, even during pregnancy. We aimed to study the association between maternal alcohol consumption during pregnancy and the child's cognitive performance using the Kaufman Assessment Battery for Children, 2nd edition (KABC-II) and the Children's Ca...

journal_title：PeerJ

authors： Sanou AS,Diallo AH,Holding P,Nankabirwa V,Engebretsen IMS,Ndeezi G,Tumwine JK,Meda N,Tylleskar T,Kashala-Abotnes E

更新日期：2017-06-30 00:00:00

abstract：:The mammalian pelvis is thought to exhibit adaptations to the functional demands of locomotor behaviors. Previous work in primates has identified form-function relationships between pelvic shape and locomotor behavior; few studies have documented such relationships in carnivorans, instead focusing on long bones. Most ...

journal_title：PeerJ

authors： Lewton KL,Brankovic R,Byrd WA,Cruz D,Morales J,Shin S

更新日期：2020-02-20 00:00:00

abstract：:Conservation initiatives to protect and restore valued species communities in human-dominated landscapes face challenges linked to their potential costs. Conservation easements on private land may represent a cost-effective alternative to land purchase, but long-term costs to monitor and enforce easements, or defend l...

journal_title：PeerJ

authors： Schuster R,Arcese P

更新日期：2015-08-13 00:00:00

abstract：:Pseudomonas syringae is the most widespread bacterial pathogen in plants. Several strains of P. syringae produce a phytotoxin, coronatine (COR), which acts as a jasmonic acid mimic and inhibits plant defense responses and contributes to disease symptom development. In this study, we found that COR inhibits early defen...

journal_title：PeerJ

authors： Lee S,Ishiga Y,Clermont K,Mysore KS

更新日期：2013-02-12 00:00:00

abstract：:We examined whether chemically mediated risk perception by prey and the effects of changes in prey behavior on basal resources vary as a function of the amount of prey biomass consumed by the predator. We studied these issues using a tritrophic system composed of blue crabs, Callinectes sapidus (top predator), mud cra...

journal_title：PeerJ

authors： Weissburg M,Beauvais J

更新日期：2015-11-19 00:00:00

abstract：:Equine Herpesviruses (EHV) are common and often latent pathogens of equids which can cause fatalities when transmitted to non-equids. Stress and elevated glucocorticoids have been associated with EHV reactivation in domestic horses, but little is known about the correlation between stress and viral reactivation in wil...

journal_title：PeerJ

authors： Seeber PA,Quintard B,Sicks F,Dehnhard M,Greenwood AD,Franz M

更新日期：2018-08-22 00:00:00

abstract：Background:Quantifying lower-limb load and asymmetry during team sport match-play may be important for injury prevention and understanding performance. However, current analysis methods of lower-limb symmetry during match-play employ wearable microtechnology that may not be best suited to the task. A popular microtechn...

journal_title：PeerJ

authors： Glassbrook DJ,Fuller JT,Alderson JA,Doyle TLA

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:Aspergillus niger, along with many other lignocellulolytic fungi, has been widely used as a commercial workhorse for cellulase production. A fungal cellulase system generally includes three major classes of enzymes i.e., β-glucosidases, endoglucanases and cellobiohydrolases. Cellobiohydrolases (CBH) are vita...

journal_title：PeerJ

authors： Woon JS,Mackeen MM,Illias RM,Mahadi NM,Broughton WJ,Murad AMA,Abu Bakar FD

更新日期：2017-10-12 00:00:00

abstract：:There is currently great interest in applying neural networks to prediction tasks in medicine. It is important for predictive models to be able to use survival data, where each patient has a known follow-up time and event/censoring indicator. This avoids information loss when training the model and enables generation ...

journal_title：PeerJ

authors： Gensheimer MF,Narasimhan B

更新日期：2019-01-25 00:00:00

abstract：:Current research posits that all multicellular organisms live in symbioses with associated microorganisms and form so-called metaorganisms or holobionts. Cnidarian metaorganisms are of specific interest given that stony corals provide the foundation of the globally threatened coral reef ecosystems. To gain first insig...

journal_title：PeerJ

authors： Brüwer JD,Voolstra CR

更新日期：2018-03-01 00:00:00

abstract：:This study evaluated pollution levels in water and sediments of Península de Paraguaná and related these levels with benthic macrofauna along a coastal area where the largest Venezuelan oil refineries have operated over the past 60 years. For this, the concentration of heavy metals, of hydrocarbon compounds and the co...

journal_title：PeerJ

authors： Croquer A,Bone D,Bastidas C,Ramos R,García E

更新日期：2016-06-23 00:00:00

abstract：:The origin of recent parallel outbreaks of the high pathogenicity H5N8 avian flu virus in Europe and in Japan can be traced to a single source population, which has most likely been spread by migratory birds. By using Bayesian coalescent methods to analyze the DNA sequences of the virus to find the times for divergenc...

journal_title：PeerJ

authors： Dalby AR,Iqbal M

更新日期：2015-04-30 00:00:00

abstract：Background:During their long evolution, Synechocystis sp. PCC6803 developed a remarkable capacity to acclimate to diverse environmental conditions. In this study, Raman spectroscopy and Raman chemometrics tools (RametrixTM) were employed to investigate the phenotypic changes in response to external stressors and correl...

journal_title：PeerJ

authors： Tanniche I,Collakova E,Denbow C,Senger RS

更新日期：2020-03-30 00:00:00

abstract：Background:Non-small cell lung cancer (NSCLC) is one of the most common malignant tumors in the world, and it has become the leading cause of death of malignant tumors. However, its mechanisms are not fully clear. The aim of this study is to investigate the key genes and explore their potential mechanisms involving in ...

journal_title：PeerJ

authors： Zhang L,Peng R,Sun Y,Wang J,Chong X,Zhang Z

更新日期：2019-12-12 00:00:00

abstract：:Current ovarian cancer treatment involves chemotherapy that has serious limitations, such as rapid clearance, unfavorable biodistribution and severe side effects. To overcome these limitations, drug delivery systems (DDS) have been developed to encapsulate chemotherapeutics for delivery to tumor cells. However, no sys...

journal_title：PeerJ

authors： Raavé R,de Vries RB,Massuger LF,van Kuppevelt TH,Daamen WF

更新日期：2015-12-10 00:00:00

abstract：:The first plants related to the ferns are represented by several extinct groups that emerged during the Devonian. Among them, the iridopterids are closely allied to the sphenopsids, a group represented today by the genus Equisetum. They have been documented in Middle to early Late Devonian deposits of Laurussia and th...

journal_title：PeerJ

authors： Champreux A,Meyer-Berthaud B,Decombeix AL

更新日期：2020-06-16 00:00:00

abstract：:The proportion of females calving (PFC) each year has been employed as an indicator of population reproductive performance in ungulates, especially for species that breed annually, because it requires less detailed population data than inter-birthing intervals and age at first reproduction. For asynchronous breeders w...

journal_title：PeerJ

authors： Law PR,Fike B

更新日期：2018-08-15 00:00:00

abstract：:Species interactions are a key component of ecosystems but we generally have an incomplete picture of who-eats-who in a given community. Different techniques have been devised to predict species interactions using theoretical models or abundances. Here, we explore the K nearest neighbour approach, with a special empha...

journal_title：PeerJ

authors： Desjardins-Proulx P,Laigle I,Poisot T,Gravel D

更新日期：2017-08-10 00:00:00

abstract：:Mutations that cause an error in the splicing of a messenger RNA (mRNA) can lead to diseases in humans. Various computational models have been developed to recognize the sequence pattern of the splice sites. In recent studies, Convolutional Neural Network (CNN) architectures were shown to outperform other existing mod...

journal_title：PeerJ

authors： Thanapattheerakul T,Engchuan W,Chan JH

更新日期：2020-07-06 00:00:00

abstract：Background:Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed class of drugs in the practice of psychiatry. Cytochrome P450 (CYP) 2C19 and CYP2D6 are established as clinically relevant drug metabolizing enzymes (DMEs) that influence the pharmacokinetics of SSRIs and may either be group...

journal_title：PeerJ

authors： Eugene AR

更新日期：2019-10-09 00:00:00

abstract：Background:Except for a few studies with contradictory observations, information is lacking on the possibility of association between DNA mismatch repair (MMR) status and the presence of cancer stem cells in colorectal carcinoma (CRC), two important aspects in colorectal carcinogenesis. Methods:Eighty (40 right-sided ...

journal_title：PeerJ

authors： Cheah PL,Li J,Looi LM,Teoh KH,Ong DB,Arends MJ

更新日期：2018-09-11 00:00:00

abstract：:Partible paternity refers to the conception belief that children can have multiple fathers ("co-fathers") and is common to indigenous cultures of lowland South America. The nature of social relationships observed between co-fathers reveals information about the reproductive strategies underlying partible paternity. He...

journal_title：PeerJ

authors： Walker RS,Yvinec C,Ellsworth RM,Bailey DH

更新日期：2015-04-14 00:00:00

abstract：:Background. Physical, visual, chemical, and auditory cues signalling fighting ability have independently evolved in many animal taxa as a means to resolve conflicts without escalating to physical aggression. Facial width-to-height ratio (fWHR, i.e., the relative width to height of the face) has been associated with do...

journal_title：PeerJ

authors： Borgi M,Majolo B

更新日期：2016-03-21 00:00:00

abstract：Background:Pandi's mushroom-tongue salamander (Bolitoglossa pandi) is one of the threatened amphibians in South America, as well as a flagship species for the Colombian conservation agenda. This species is endemic to the Andean cloud forests of the western slope of the Cordillera Oriental of Colombia, occurring only in...

journal_title：PeerJ

authors： Angarita-Sierra T,Bonilla-Gómez MA,Sánchez DA,Acosta-Galvis AR,Medina-Ovalle H,Solano-Moreno A,Ulloa-Rengifo S,Guevara-Guevara D,Torres-Ramirez JJ,Curaca-Fierro S,Cabrera-Amaya DM,Infante-Betancour JA,Londoño-Montaño LF,Albarán

更新日期：2020-09-24 00:00:00

abstract：:Loot boxes are items in video games that may be paid for with real-world money, but which contain randomised contents. There is a reliable correlation between loot box spending and problem gambling severity: the more money gamers spend on loot boxes, the more severe their problem gambling tends to be. However, it is u...

journal_title：PeerJ

authors： Zendle D

更新日期：2019-10-29 00:00:00

abstract：:The vibrating reed frequency meter, originally employed by Békésy and later by Wilson as a cochlear model, uses a set of tuned reeds to represent the cochlea's graded bank of resonant elements and an elastic band threaded between them to provide nearest-neighbour coupling. Here the system, constructed of 21 reeds prog...

journal_title：PeerJ

authors： Bell A,Wit HP

更新日期：2015-10-13 00:00:00

abstract：Background:Maize (Zea mays L.) is a principal cereal crop cultivated worldwide for human food, animal feed, and more recently as a source of biofuel. However, as a direct consequence of water insufficiency and climate change, frequent occurrences of both biotic and abiotic stresses have been reported in various regions...

journal_title：PeerJ

authors： Kimotho RN,Baillo EH,Zhang Z

更新日期：2019-07-08 00:00:00

abstract：:Myocardial infarction has been carefully studied in numerous experimental models. Most of these models are based on electrophysiological and functional data, and pay less attention to histological discoveries. During the last decade, treatment using advanced therapies, mainly cell therapy, has prevailed from among all...

journal_title：PeerJ

authors： García Gómez-Heras S,Largo C,Larrea JL,Vega-Clemente L,Calderón Flores M,Ruiz-Pérez D,García-Olmo D,García-Arranz M

更新日期：2019-07-22 00:00:00

abstract：:The core antigen of the hepatitis C virus (HCV Ag) presents an alternative marker to HCV RNA when screening patients for HCV viremia. This study sought to evaluate the utility of HCV Ag as a marker to assess active HCV infection in individuals residing in an HCV-endemic area. From 298 HCV-seropositive individuals eval...

journal_title：PeerJ

authors： Wasitthankasem R,Vichaiwattana P,Auphimai C,Siripon N,Klinfueng S,Tangkijvanich P,Vongpunsawad S,Poovorawan Y

更新日期：2017-11-06 00:00:00

abstract：Background:Cognitive dysfunction in fibromyalgia (FM) encompasses objective cognitive difficulties, as measured in neuropsychological tests, and self-reported cognitive complaints. Although it has been suggested that FM patients display problems in working memory, the data are inconsistent, and the overall working memo...

journal_title：PeerJ

authors： Pidal-Miranda M,González-Villar AJ,Carrillo-de-la-Peña MT,Andrade E,Rodríguez-Salgado D

更新日期：2018-11-21 00:00:00