A scalable discrete-time survival model for neural networks.

abstract：:Knowledge on the precise identification of fish resources is critical for sustainable fisheries management. This study employs the DNA barcoding approach to generate a molecular taxonomic catalogue of commercially important reef fishes in the waters of Weh Island (Aceh Province), the most northerly inhabited island in...

journal_title：PeerJ

authors： Fadli N,Mohd Nor SA,Othman AS,Sofyan H,Muchlisin ZA

更新日期：2020-08-05 00:00:00

abstract：Background:As key negative regulators of gene expression, microRNAs (miRNAs) play an important role in the onset and progression of hepatocellular carcinoma (HCC). This study aimed to identify the miRNAs involved in HCC carcinogenesis and their regulated genes. Methods:The Gene Expression Omnibus (GEO) dataset (GSE108...

journal_title：PeerJ

authors： Liu Y,Cao Y,Cai W,Wu L,Zhao P,Liu XG

更新日期：2020-04-29 00:00:00

abstract：Background:Many fish taxa produce sound in voluntary and in disturbance contexts but information on the full acoustic repertoire is lacking for most species. Yet, this knowledge is critical to enable monitoring fish populations in nature through acoustic monitoring. Methods:In this study we characterized the sounds em...

journal_title：PeerJ

authors： Pereira BP,Vieira M,Pousão-Ferreira P,Candeias-Mendes A,Barata M,Fonseca PJ,Amorim MCP

更新日期：2020-02-24 00:00:00

abstract：:Physical exercise is linked to individuals whose affect profiles are invariably positive and it induces anti-apoptotic and anti-excitotoxic effects, buttressing blood-brain barrier intactness in both healthy individuals and those suffering from disorders accompanying overweight and obesity. In this regard, exercise of...

journal_title：PeerJ

authors： Garcia D,Archer T

更新日期：2014-12-16 00:00:00

abstract：Introduction:Metabolomics has emerged as a valuable tool to discover novel biomarkers and study the pathophysiology of diabetic nephropathy (DN). However, the effect of postoperative acute kidney injury (AKI) on diabetes mellitus (DM) to chronic DN progression has not been evaluated from the perspective of metabolomics...

journal_title：PeerJ

authors： Wang J,Yan W,Zhou X,Liu Y,Tang C,Peng Y,Liu H,Sun L,Xiao L,He L

更新日期：2020-05-14 00:00:00

abstract：:Barnacles and their allies (Thecostraca) are a biologically diverse, monophyletic crustacean group, which includes both intensely studied taxa, such as the acorn and stalked barnacles, as well as cryptic taxa, for example, Facetotecta. Recent efforts have clarified phylogenetic relationships in many different parts of...

journal_title：PeerJ

authors： Ewers-Saucedo C,Owen CL,Pérez-Losada M,Høeg JT,Glenner H,Chan BKK,Crandall KA

更新日期：2019-08-16 00:00:00

abstract：:Live trapping is a common tool used to assess demography of small mammals. However, live-trapping is often expensive and stressful to captured individuals. Thus, assessing the relative tradeoffs among study goals, project expenses, and animal well-being is necessary. Here, we evaluated how apparent bias and precision ...

journal_title：PeerJ

authors： Weldy MJ,Wilson TM,Lesmeister DB,Epps CW

更新日期：2019-10-03 00:00:00

abstract：Background:This study was performed to determine the characteristics of community cats that were admitted to trap-neuter-return(TNR) programs and the feasibility of the high-quality, high-volume spay/neuter (HQHVSN) model in Seoul, Korea. Methods:TNR programs were performed eight times from 2017 to 2018, and a total o...

journal_title：PeerJ

authors： Cho Y,Kim K,Kim MS,Lee I

更新日期：2020-03-05 00:00:00

abstract：:Populations of passively dispersed organisms in continental aquatic habitats typically show high levels of neutral genetic differentiation despite their high dispersal capabilities. Several evolutionary factors, including founder events, local adaptation, and life cycle features such as high population growth rates an...

journal_title：PeerJ

authors： Montero-Pau J,Gómez A,Serra M

更新日期：2018-12-11 00:00:00

abstract：:Tuberculosis (TB) is a worldwide health, economic, and social burden, especially in developing countries. Drug-resistant TB is the most serious type of this burden. Thus, it is necessary to screen drug-resistant mutations by using a simple and rapid detection method. A total of 32 pairs of allele-specific PCR (AS-PCR)...

journal_title：PeerJ

authors： Yang P,Song Y,Xia X,Zhang AM

更新日期：2019-04-01 00:00:00

abstract：Background:A key step in embryo implantation is the adhesion to and invasion of the endometrium by the blastocyst trophectoderm. The envelope proteins of HERV-W and -FRD (human endogenous retrovirus-W and -FRD), syncytin-1 and syncytin-2, are mainly distributed in the placenta, and play important roles in the developme...

journal_title：PeerJ

authors： Guo L,Gu F,Xu Y,Zhou C

更新日期：2020-11-17 00:00:00

abstract：:[This corrects the article DOI: 10.7717/peerj.4029.]. ...

journal_title：PeerJ

authors： Lang JM,Coil DA,Neches RY,Brown WE,Cavalier D,Severance M,Hampton-Marcell JT,Gilbert JA,Eisen JA

更新日期：2018-02-27 00:00:00

abstract：:A new species of brittle star, Ophiomitrella floorae, is recorded from the lower two meters of the Gronsveld Member (Maastricht Formation), of late Maastrichtian age (c. 66.7 Ma). These relatively fine-grained biocalcarenites reflect shallow-water deposition in a sheltered setting with a relatively firm sea floor and ...

journal_title：PeerJ

authors： Thuy B,Numberger-Thuy L,Jagt JWM

更新日期：2020-08-24 00:00:00

abstract：:Myocardial infarction has been carefully studied in numerous experimental models. Most of these models are based on electrophysiological and functional data, and pay less attention to histological discoveries. During the last decade, treatment using advanced therapies, mainly cell therapy, has prevailed from among all...

journal_title：PeerJ

authors： García Gómez-Heras S,Largo C,Larrea JL,Vega-Clemente L,Calderón Flores M,Ruiz-Pérez D,García-Olmo D,García-Arranz M

更新日期：2019-07-22 00:00:00

abstract：:Much genomic-scale, especially transcriptomic, data on spider phylogeny has accumulated in the last few years. These data have recently been used to investigate the diverse architectures and the origin of spider webs, concluding that the ancestral spider spun no foraging web, that spider webs evolved de novo 10-14 tim...

journal_title：PeerJ

authors： Coddington JA,Agnarsson I,Hamilton CA,Bond JE

更新日期：2019-04-04 00:00:00

abstract：:Diarrhea is a syndrome of digestive disorders in young rabbits and may lead to secondary infections resulting in reduced immunity and higher mortality in baby rabbits, with serious impacts on rabbit farming. In this study, we investigated the effects of diarrhea on the health of baby rabbits in terms of intestinal muc...

journal_title：PeerJ

authors： Chen Y,Zhao B,Wu Y,Hu S,Mu L,Zhu C,Pan Y,Wu X

更新日期：2017-11-27 00:00:00

abstract：:Coastal habitats in Chile are hypothesized to support a number of diadromous fish species. The objective of this study was to document migratory life histories of native galaxiids and introduced salmonids from a wide latitudinal range in Chilean Patagonia (39-48°S). Otolith microchemistry data were analysed using a re...

journal_title：PeerJ

authors： Alò D,Correa C,Samaniego H,Krabbenhoft CA,Turner TF

更新日期：2019-01-03 00:00:00

abstract：:Single-cell analysis has the potential to provide us with a host of new knowledge about biological systems, but it comes with the challenge of correctly interpreting the biological information. While emerging techniques have made it possible to measure inter-cellular variability at the transcriptome level, no consensu...

journal_title：PeerJ

authors： Kippner LE,Kim J,Gibson G,Kemp ML

更新日期：2014-06-24 00:00:00

abstract：:Coarse-grained (CG) models have been successful in simulating the chemical properties of lipid bilayers, but accurate treatment of membrane proteins and lipid-protein molecular interactions remains a challenge. The CgProt force field, original developed with the multiscale coarse graining method, is assessed by compar...

journal_title：PeerJ

authors： Hills RD Jr

更新日期：2018-01-10 00:00:00

abstract：:Seabed mapping can quantify the extent of benthic habitats that comprise marine ecosystems, and assess the impact of fisheries on an ecosystem. In this study, the distribution of seabed habitats in a proposed no-take Marine Reserve along the northeast coast of Great Barrier Island, New Zealand, was mapped using underw...

journal_title：PeerJ

authors： Lee ST,Kelly M,Langlois TJ,Costello MJ

更新日期：2015-12-10 00:00:00

abstract：:We present a semi-empirical (PM6-based) computational method for systematically estimating the effect of all possible single mutants, within a certain radius of the active site, on the barrier height of an enzymatic reaction. The intent of this method is not a quantitative prediction of the barrier heights, but rather...

journal_title：PeerJ

authors： Hediger MR,Steinmann C,De Vico L,Jensen JH

更新日期：2013-07-23 00:00:00

abstract：:The MYB transcription factor family is one of the largest gene families playing regulatory roles in plant growth and development. The MYB family has been studied in a variety of plant species but has not been reported in Taxus chinensis. Here we identified 72 putative R2R3-MYB genes in T. chinensis using a comprehensi...

journal_title：PeerJ

authors： Hu X,Zhang L,Wilson I,Shao F,Qiu D

更新日期：2020-02-17 00:00:00

abstract：:Since 2014, Stony Coral Tissue Loss Disease (SCTLD) has led to mass mortality of the majority of hard coral species on the Florida Reef Tract. Following the successful treatment of SCTLD lesions on laboratory corals using water dosed with antibiotics, two topical pastes were developed as vehicles to directly apply ant...

journal_title：PeerJ

authors： Neely KL,Macaulay KA,Hower EK,Dobler MA

更新日期：2020-06-09 00:00:00

abstract：:The culture of pelagic marine invertebrates, especially the ctenophore Mnemiopsis leidyi, has been demonstrated in past studies dating back to the 1960s; however, the mass culture of delicate pelagic invertebrates has remained elusive. By using a pair of acrylic tubes and enabling water diffusion between them, we have...

journal_title：PeerJ

authors： Patry WL,Bubel M,Hansen C,Knowles T

更新日期：2020-04-07 00:00:00

abstract：:For the past several centuries, millipede taxonomists have used the morphology of male copulatory structures (modified legs called gonopods), which are strongly variable and suggestive of species-level differences, as a source to understand taxon relationships. Millipedes in the family Xystodesmidae are blind, dispers...

journal_title：PeerJ

authors： Means JC,Marek PE

更新日期：2017-10-12 00:00:00

abstract：:The aim of this study was to analyze the influence of smoking habits and other possibly relevant factors on dental implant survival. The study population included all patients who underwent dental implants between the years 1999 and 2008 at a large military dental clinic and were examined in the periodic medical exami...

journal_title：PeerJ

authors： Twito D,Sade P

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:Amoebiasis is the third most common parasitic cause of morbidity and mortality, particularly in countries with poor hygienic settings. There exists an ambiguity in the diagnosis of amoebiasis, and hence there arises a necessity for a better diagnostic approach. Serine-rich Entamoeba histolyticaprotein (SREHP...

journal_title：PeerJ

authors： Manochitra K,Parija SC

更新日期：2017-06-28 00:00:00

abstract：BACKGROUND:The scholarly publication landscape is changing rapidly. We investigated whether the introduction of an institutional publications officer might help facilitate better knowledge of publication topics and related resources, and effectively support researchers to publish. METHODS:In September 2015, a purpose-...

journal_title：PeerJ

authors： Cobey KD,Galipeau J,Shamseer L,Moher D

更新日期：2017-05-31 00:00:00

abstract：:Objectives. Diabetes mellitus (DM) and hypothyroidism are each associated with increased rate of pregnancy complications. However, their combined morbidity during gestation is poorly studied. Therefore, the aims of this study were to determine the prevalence of the combined morbidity of DM & hypothyroidism and whether...

journal_title：PeerJ

authors： Tirosh D,Benshalom-Tirosh N,Novack L,Press F,Beer-Weisel R,Wiznitzer A,Mazor M,Erez O

更新日期：2013-03-19 00:00:00

abstract：:The increase in bioinformatics resources such as tools/scripts and databases poses a great challenge for users seeking to construct interactive and reproducible biological data analysis applications. Here, we propose an open-source, comprehensive, flexible R package named BioInstaller that consists of the R functions,...

journal_title：PeerJ

authors： Li J,Cui B,Dai Y,Bai L,Huang J

更新日期：2018-10-31 00:00:00