BioInstaller: a comprehensive R package to construct interactive and reproducible biological data analysis applications based on the R platform.

abstract：BACKGROUND:Schotia brachypetala Sond. (Fabaceae) is an endemic tree of Southern Africa whose phytochemistry and pharmacology were slightly studied. The present work aimed at profiling the major phenolics compounds present in the hydro-alcohol extract from S. brachypetala leaves (SBE) using LC/HRESI/MS/MS and NMR and pr...

journal_title：PeerJ

authors： Sobeh M,ElHawary E,Peixoto H,Labib RM,Handoussa H,Swilam N,El-Khatib AH,Sharapov F,Mohamed T,Krstin S,Linscheid MW,Singab AN,Wink M,Ayoub N

更新日期：2016-11-15 00:00:00

abstract：:The post-genomic era is characterized by the direct acquisition and analysis of genomic data with many applications, including the enhancement of the understanding of microbial epidemiology and pathology. However, there are a number of molecular approaches to survey pathogen diversity, and the impact of these differen...

journal_title：PeerJ

authors： Castro-Nallar E,Hasan NA,Cebula TA,Colwell RR,Robison RA,Johnson WE,Crandall KA

更新日期：2015-02-17 00:00:00

abstract：Background:Inhibition processing is sensitive to aging, and an age-related decline in inhibition processing has been associated with an accelerated rate of progression to Alzheimer disease. Elderly women are two to three times more likely than age-matched men to have Alzheimer disease. Therefore, this study examined wh...

journal_title：PeerJ

authors： Xu C,Lu Y,Wang B,Zhou C

更新日期：2019-03-18 00:00:00

abstract：Background:E-health technology applications are essential tools of modern information technology that improve quality of healthcare delivery in hospitals of both developed and developing countries. However, despite its positive benefits, studies indicate that the rate of the e-health adoption in some developing countri...

journal_title：PeerJ

authors： Zayyad MA,Toycan M

更新日期：2018-03-01 00:00:00

abstract：Background:Grazing activity on periphytic mats determines mat structure and spatial heterogeneity. Spatial complexity in stream periphyton is highly divergent and may depend on the functional traits of the different primary consumers species (i.e., grazers) such as mouthpart morphology, feeding behavior, and feeding ac...

journal_title：PeerJ

authors： Katano I,Doi H

更新日期：2019-06-05 00:00:00

abstract：BACKGROUND:Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid peptides were examined. METHODS:TEM, SEM and ATP efflux ...

journal_title：PeerJ

authors： Jindal HM,Zandi K,Ong KC,Velayuthan RD,Rasid SM,Samudi Raju C,Sekaran SD

更新日期：2017-10-05 00:00:00

abstract：:Sanderlings (Calidris alba) are long-distance migratory shorebirds with a non-breeding range that spans temperate and tropical coastal habitats. Breeding in the High Arctic combined with non-breeding seasons in the tropics necessitate long migrations, which are energetically demanding. On an annual basis, the higher e...

journal_title：PeerJ

authors： Grond K,Ntiamoa-Baidu Y,Piersma T,Reneerkens J

更新日期：2015-08-11 00:00:00

abstract：:Automatic species classification of birds from their sound is a computational tool of increasing importance in ecology, conservation monitoring and vocal communication studies. To make classification useful in practice, it is crucial to improve its accuracy while ensuring that it can run at big data scales. Many appro...

journal_title：PeerJ

authors： Stowell D,Plumbley MD

更新日期：2014-07-17 00:00:00

abstract：:The consumption of raw fish has increased considerably in the West, since it is said to be potentially healthier than processed fish (for containing omega 3 and 6, essential amino acids and vitamins). However this potential benefit, as well as the taste, value and even the risk of extinction are not the same for all s...

journal_title：PeerJ

authors： Staffen CF,Staffen MD,Becker ML,Löfgren SE,Muniz YCN,de Freitas RHA,Marrero AR

更新日期：2017-11-29 00:00:00

abstract：Purpose:Yes associated protein 1 (YAP1), which is a standout amongst the most essential effectors of the Hippo pathway, assumes a vital part in a few kinds of cancer. However, whether YAP1 is an oncogene in CRC (colorectal cancer) remains controversial, and the association between the subcellular localization of YAP1 a...

journal_title：PeerJ

authors： Dong T,Yuan Y,Xiang X,Sang S,Shen H,Wang L,Yang C,Li F,Li H,Zheng S

更新日期：2020-11-19 00:00:00

abstract：:Quantitative morphometric analyses, particularly ontogenetic allometry, are common methods used in quantifying shape, and changes therein, in both extinct and extant organisms. Due to incompleteness and the potential for restricted sample sizes in the fossil record, palaeobiological analyses of allometry may encounter...

journal_title：PeerJ

authors： Brown CM,Vavrek MJ

更新日期：2015-03-10 00:00:00

abstract：:Mauremys reevesii is a classical organism with temperature-dependent sex determination (TSD). Gonad development in early life has recently received considerable attention but gonadal maintenance after sex differentiation in turtles with TSD remains a mystery. In this study, we sequenced the transcriptomes for the adul...

journal_title：PeerJ

authors： Xiong L,Dong J,Jiang H,Zan J,Tong J,Liu J,Wang M,Nie L

更新日期：2019-03-08 00:00:00

abstract：:The spatial learning skills of high and low stress juvenile mulloway (Argyrosomus japonicus) were tested in a dichotomous choice apparatus. Groups of fish were formed based on background blood cortisol levels and required to learn the location of a food reward hidden in one of two compartments. Low stress fish charact...

journal_title：PeerJ

authors： Raoult V,Trompf L,Williamson JE,Brown C

更新日期：2017-06-08 00:00:00

abstract：:The recent publication of a number of high resolution bacterial voltage-gated sodium channel structures has opened the door for the mechanisms employed by these channels to distinguish between ions to be elucidated. The way these channels select between Na(+) and K(+) has been investigated in computational studies, bu...

journal_title：PeerJ

authors： Corry B

更新日期：2013-02-12 00:00:00

abstract：:In contrast to dominant mode of ecological transition in the evolution of marine mammals, different lineages of toothed whales (Odontoceti) have repeatedly invaded freshwater ecosystems during the Cenozoic era. The so-called 'river dolphins' are now recognized as independent lineages that converged on similar morpholo...

journal_title：PeerJ

authors： Pyenson ND,Vélez-Juarbe J,Gutstein CS,Little H,Vigil D,O'Dea A

更新日期：2015-09-01 00:00:00

abstract：:While studying organisms living in association with the solitary tunicate Phallusia nigra (Ascidiacea, Ascidiidae) from a shallow fringing reef at Zeytouna Beach (Egyptian Red Sea), one of the collected ascidians showed peculiar perforations on its tunic. Once dissected, the perforations revealed to be the openings of...

journal_title：PeerJ

authors： Martin D,Nygren A,Cruz-Rivera E

更新日期：2017-06-01 00:00:00

abstract：Background:Oil spills can cause severe damage within a marine ecosystem. Following a spill, the soluble fraction of polycyclic aromatic hydrocarbons is rapidly released into the water column. These remain dissolved in seawater over an extended period of time, even should the insoluble fraction be removed. The vertical ...

journal_title：PeerJ

authors： Kryzevicius Z,Mickuviene K,Bucas M,Vilkiene M,Zukauskaite A

更新日期：2020-10-27 00:00:00

abstract：Background:This study evaluates the generalizability of an eight-station progress clinical skills examination and assesses the growth in performance for six clinical skills domains among first- and second-year medical students over four time points during the academic year. Methods:We conducted a generalizability stud...

journal_title：PeerJ

authors： Laird-Fick HS,Chang C,Wang L,Parker C,Malinowski R,Emery M,Solomon DJ

更新日期：2020-05-01 00:00:00

abstract：:[This corrects the article DOI: 10.7717/peerj.2869.]. ...

journal_title：PeerJ

authors： Qiu S,Sun H,Liu Y,Kanu JS,Li R,Yu Y,Huang X,Li B,Zhang X

更新日期：2017-12-07 00:00:00

abstract：Background:This study assessed whether serum lipid levels are associated with the risk of symptomatic intracerebral hemorrhage (sICH) and functional outcomes in patients with acute ischemic stroke after receiving intravenous thrombolysis. Methods:We retrospectively analyzed consecutive ischemic stroke patients who wer...

journal_title：PeerJ

authors： Lin TC,Lin YK,Chen CI,Chan L,Chi NF,Yuan RY,Sheu JJ,Wei CR,Tsai JP,Yeh TH

更新日期：2018-11-23 00:00:00

abstract：:The amphibian skin microbiome has been the focus of recent studies aiming to better understand the role of these microbial symbionts in host defense against disease. However, host-associated microbial communities are complex and dynamic, and changes in their composition and structure can influence their function. Unde...

journal_title：PeerJ

authors： Estrada A,Hughey MC,Medina D,Rebollar EA,Walke JB,Harris RN,Belden LK

更新日期：2019-06-21 00:00:00

abstract：:The marine gastropod, Coralliophila abbreviata, is an obligate corallivore that causes substantial mortality in Caribbean Acropora spp. Considering the imperiled status of Acropora cervicornis and A. palmata, a better understanding of ecological interactions resulting in tissue loss may enable more effective conservat...

journal_title：PeerJ

authors： Bright AJ,Cameron CM,Miller MW

更新日期：2015-09-10 00:00:00

abstract：Background:Kinorhynchs are marine, microscopic invertebrates inhabiting the seafloors. Their segmented trunk equipped with spines and processes has inspired scientists to give them the common name "mud dragons." Even though kinorhynchs have been known since the 19th century, less than 300 species are known to science, ...

journal_title：PeerJ

authors： Sørensen MV,Grzelak K

更新日期：2018-09-28 00:00:00

abstract：:Tyrosine phosphorylation has emerged as an important regulator of plasma membrane-localized immune receptors activity. Here, we investigate the role of tyrosine phosphorylation in the regulation of rice XANTHOMONAS RESISTANCE 21 (XA21)-mediated immunity. We demonstrate that the juxtamembrane and kinase domain of Esche...

journal_title：PeerJ

authors： Caddell DF,Wei T,Sharma S,Oh MH,Park CJ,Canlas P,Huber SC,Ronald PC

更新日期：2018-12-11 00:00:00

abstract：:Weaning is an important event for all mammals, including young forest musk deer. However, weaning stress may cause intestinal microbiota-related disorders. Therefore, high-throughput 16S rRNA gene sequencing was applied to study the dynamic changes in intestinal microbiota during pre-weaning (10 days before weaning) a...

journal_title：PeerJ

authors： Li Y,Shi M,Zhang T,Hu X,Zhang B,Xu S,Ding J,Hu D,Liu S

更新日期：2020-04-13 00:00:00

abstract：Background:Prognostic genes in the tumor microenvironment play an important role in immune biological processes and the response of cancer to immunotherapy. Thus, we aimed to assess new biomarkers that are associated with immune/stromal cells in lung adenocarcinomas (LUAD) using the ESTIMATE algorithm, which also signi...

journal_title：PeerJ

authors： Xu ZY,Zhao M,Chen W,Li K,Qin F,Xiang WW,Sun Y,Wei J,Yuan LQ,Li SK,Lin SH

更新日期：2020-07-23 00:00:00

abstract：:Pathogens invading the mammary gland are recognized through a range of pattern recognition receptors (PRRs), residing on the plasma membrane of mammary epithelial cells. Toll-like receptor 2 (TLR2) signalling is responsible for recognition of Gram-positive bacteria, which are the most common mastitis-causing pathogens...

journal_title：PeerJ

authors： Ogorevc J,Simčič M,Zorc M,Škrjanc M,Dovč P

更新日期：2019-07-31 00:00:00

abstract：:Avoidance behavior involves learning responses that prevent upcoming aversive events; these responses typically extinguish when the aversive events stop materializing. Stimuli that signal safety from aversive events can paradoxically inhibit extinction of avoidance behavior. In animals, males and females process safet...

journal_title：PeerJ

authors： Radell ML,Beck KD,Pang KC,Myers CE

更新日期：2015-07-14 00:00:00

abstract：Background:Influenza A (H5N1) virus is a global concern with potential as a pandemic threat. High sequence variability of influenza A viruses is a major challenge for effective vaccine design. A continuing goal towards this is a greater understanding of influenza A (H5N1) proteome sequence diversity in the context of t...

journal_title：PeerJ

authors： Abd Raman HS,Tan S,August JT,Khan AM

更新日期：2020-05-27 00:00:00

abstract：:The family Pseudopimelodidae is widely distributed in South America and includes 51 described species organized in seven genera. Only two of four species of the genus Pseudopimelodus have been recorded for the trans-Andean basins of Colombia, Pseudopimelodus bufonius and P. schultzi, whose similarity in external morph...

journal_title：PeerJ

authors： Restrepo-Gómez AM,Rangel-Medrano JD,Márquez EJ,Ortega-Lara A

更新日期：2020-09-03 00:00:00