Refining amino acid hydrophobicity for dynamics simulation of membrane proteins.

abstract：Background:We investigated the effects of gastric Helicobacter pylori infection on the daytime and overnight human oral microbiota. Methods:Twenty four volunteers were recruited. Ten tested positive for H. pylori infection by the Carbon-14 Urea Breath Test, and the rest were negative. Two oral swabs were collected: on...

journal_title：PeerJ

authors： Chua EG,Chong JY,Lamichhane B,Webberley KM,Marshall BJ,Wise MJ,Tay CY

更新日期：2019-01-28 00:00:00

abstract：:Understanding how structural and functional alterations of individual tissues impact on whole-joint function is challenging, particularly in humans where direct invasive experimentation is difficult. Finite element (FE) computational models produce quantitative predictions of the mechanical and physiological behaviour...

journal_title：PeerJ

authors： Peters AE,Akhtar R,Comerford EJ,Bates KT

更新日期：2018-01-25 00:00:00

abstract：Background:Large and complex mounds built by termites of the genus Macrotermes characterize many dry African landscapes, including the savannas, bushlands, and dry forests of the Tsavo Ecosystem in southern Kenya. The termites live in obligate symbiosis with filamentous fungi of the genus Termitomyces. The insects coll...

journal_title：PeerJ

authors： Vesala R,Harjuntausta A,Hakkarainen A,Rönnholm P,Pellikka P,Rikkinen J

更新日期：2019-01-16 00:00:00

abstract：:Sugarcane contributes 80% of global sugar production and to bioethanol generation for the bioenergy industry. Its productivity is threatened by drought that can cause up to 60% yield loss. This study used RNA-Seq to gain a better understanding of the underlying mechanism by which drought-tolerant sugarcane copes with ...

journal_title：PeerJ

authors： Nawae W,Shearman JR,Tangphatsornruang S,Punpee P,Yoocha T,Sangsrakru D,Naktang C,Sonthirod C,Wirojsirasak W,Ukoskit K,Sriroth K,Klomsa-Ard P,Pootakham W

更新日期：2020-07-28 00:00:00

abstract：:Recently, herbal drugs and their bioactive compounds have gained popularity in the management of diabetes mellitus (DM), which has become an epidemic disease all over the world and is especially prevalent in the Kingdom of Saudi Arabia (KSA). This study aimed to investigate the antidiabetic effect of ethanolic and aqu...

journal_title：PeerJ

authors： Gad-Elkareem MAM,Abdelgadir EH,Badawy OM,Kadri A

更新日期：2019-02-18 00:00:00

abstract：:The amphibian skin microbiome has been the focus of recent studies aiming to better understand the role of these microbial symbionts in host defense against disease. However, host-associated microbial communities are complex and dynamic, and changes in their composition and structure can influence their function. Unde...

journal_title：PeerJ

authors： Estrada A,Hughey MC,Medina D,Rebollar EA,Walke JB,Harris RN,Belden LK

更新日期：2019-06-21 00:00:00

abstract：:The Natural Mortality coefficient (M) is a key parameter for stock assessments. The need to establish age-specific natural mortality coefficients is widely recognized because M decreases rapidly over the early stages of the life cycle until it reaches a stable M value around the age-at-maturity. The aim of this study ...

journal_title：PeerJ

authors： Romero-Gallardo S,Velázquez-Abunader I,López-Rocha JA,Garza-Gisholt E

更新日期：2018-07-18 00:00:00

abstract：:Quantitative morphometric analyses, particularly ontogenetic allometry, are common methods used in quantifying shape, and changes therein, in both extinct and extant organisms. Due to incompleteness and the potential for restricted sample sizes in the fossil record, palaeobiological analyses of allometry may encounter...

journal_title：PeerJ

authors： Brown CM,Vavrek MJ

更新日期：2015-03-10 00:00:00

abstract：:The genus Elatine contains ca 25 species, all of which are small, herbaceous annuals distributed in ephemeral waters on both hemispheres. However, due to a high degree of morphological variability (as a consequence of their amphibious life-style), the taxonomy of this genus remains controversial. Thus, to fill this ga...

journal_title：PeerJ

authors： Sramkó G,Molnár V A,Tóth JP,Laczkó L,Kalinka A,Horváth O,Skuza L,Lukács BA,Popiela A

更新日期：2016-12-21 00:00:00

abstract：:Background. Exercise at moderate intensity may confer neuroprotective benefits in multiple sclerosis (MS), however it has been reported that people with MS (PwMS) exercise less than national guideline recommendations. We aimed to determine predictors of moderate to vigorous exercise among a sample of older Canadians w...

journal_title：PeerJ

authors： Ploughman M,Harris C,Wallack EM,Drodge O,Beaulieu S,Mayo N,Health Lifestyle and Aging with MS Canadian Consortium.

更新日期：2015-08-06 00:00:00

abstract：:In group-living animals, heterogeneity in individuals' social connections may mediate the sharing of microbial infectious agents. In this regard, the genetic relatedness of individuals' commensal gut bacterium Escherichia coli may be ideal to assess the potential for pathogen transmission through animal social network...

journal_title：PeerJ

authors： Balasubramaniam K,Beisner B,Guan J,Vandeleest J,Fushing H,Atwill E,McCowan B

更新日期：2018-01-17 00:00:00

abstract：:Amazonian bamboo forests dominated by large woody bamboo plants in the genus Guadua cover approximately 180,000 km2 and represent a key resource for many organisms. In southwestern Amazonia, native bamboo forests differ in structure, biodiversity, and growth dynamics from other forest types in the region. However, wit...

journal_title：PeerJ

authors： Jacobs JM,von May R,Kavanaugh DH,Connor EF

更新日期：2018-07-03 00:00:00

abstract：:Objectives. Diabetes mellitus (DM) and hypothyroidism are each associated with increased rate of pregnancy complications. However, their combined morbidity during gestation is poorly studied. Therefore, the aims of this study were to determine the prevalence of the combined morbidity of DM & hypothyroidism and whether...

journal_title：PeerJ

authors： Tirosh D,Benshalom-Tirosh N,Novack L,Press F,Beer-Weisel R,Wiznitzer A,Mazor M,Erez O

更新日期：2013-03-19 00:00:00

abstract：Background:Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed class of drugs in the practice of psychiatry. Cytochrome P450 (CYP) 2C19 and CYP2D6 are established as clinically relevant drug metabolizing enzymes (DMEs) that influence the pharmacokinetics of SSRIs and may either be group...

journal_title：PeerJ

authors： Eugene AR

更新日期：2019-10-09 00:00:00

abstract：Background:Complement factor C3 represents the central component of the complement cascade and its activation split product C3a plays an important role in inflammation and disease. Many human disorders are linked to dysregulation of the complement system and alteration in interaction molecules. Therefore, various thera...

journal_title：PeerJ

authors： Winnicki W,Pichler P,Mechtler K,Imre R,Steinmacher I,Sengölge G,Knafl D,Beilhack G,Wagner L

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:The Saururaceae, a very small family of Piperales comprising only six species in four genera, have a relatively scanty fossil record outside of Europe. The phylogenetic relationships of the four genera to each other are resolved, with the type genus Saururus occurring in both eastern North America and East A...

journal_title：PeerJ

authors： Grímsson F,Grimm GW,Zetter R

更新日期：2017-06-13 00:00:00

abstract：:Rao's quadratic diversity index is one of the most widely applied diversity indices in functional and phylogenetic ecology. The standard way of computing Rao's quadratic diversity index for an ecological assemblage with a group of species with varying abundances is to sum the functional or phylogenetic distances betwe...

journal_title：PeerJ

authors： Chen Y,Wu Y,Shen TJ

更新日期：2018-07-06 00:00:00

abstract：Objectives:The purpose of this study is to investigate the patterns of complementary and alternative medicine use and its association with time to conventional treatment. Design:A cross-sectional study design was designed. Setting and participants:The study was performed at the Chonburi Cancer Hospital, with chart re...

journal_title：PeerJ

authors： Chotipanich A,Sooksrisawat C,Jittiworapan B

更新日期：2019-06-14 00:00:00

abstract：:The mature spermatozoa of Stephanostomum murielae and Stephanostomoides tenuis are described by transmission electron microscopy. They present several ultrastructural features previously reported in other digeneans. Their spermatozoa possess two axonemes of different length showing the 9 + '1' trepaxonematan pattern, ...

journal_title：PeerJ

authors： Bakhoum AJ,Quilichini Y,Justine JL,Bray RA,Bâ CT,Marchand B

更新日期：2015-02-12 00:00:00

abstract：:Earthworms enrich the soil and protect the health of their ecological environment. Previous studies on these invertebrates determined their protein content, hormone secretions, medicinal value, and ecological habits, but their whole genomic sequence remains incomplete. We performed whole genome sequencing of Metaphire...

journal_title：PeerJ

authors： Jin F,Zhou Z,Guo Q,Liang Z,Yang R,Jiang J,He Y,Zhao Q,Zhao Q

更新日期：2020-11-12 00:00:00

abstract：:Transgenerational effects are important for phenotypic plasticity and adaptation of marine invertebrates in the changing ocean. Ultraviolet-B (UV-B) radiation is an increasing threat to marine invertebrates. For the first time, we reported positive and negative transgenerational effects of UV-B radiation on egg size, ...

journal_title：PeerJ

authors： Ding J,Zhang L,Sun J,Shi D,Chi X,Yang M,Chang Y,Zhao C

更新日期：2019-08-26 00:00:00

abstract：:Hypocotyl elongation is a critical sign of seed germination and seedling growth, and it is regulated by multi-environmental factors. Light, temperature, and water potential are the major environmental stimuli, and their regulatory mechanism on hypocotyl growth has been extensively studied at molecular level. However, ...

journal_title：PeerJ

authors： Wang H,Shang Q

更新日期：2020-05-26 00:00:00

abstract：:In contrast to reports of wild primates, studies of captive primates' flexibility often reveal conservatism: individuals are unable to switch to new and more efficient strategies when task demands change. We propose that such conservatism might be a result of task design and hypothesize that conservatism might be link...

journal_title：PeerJ

authors： Jacobson SL,Hopper LM

更新日期：2019-01-08 00:00:00

abstract：Background:Acute respiratory distress syndrome (ARDS) is associated with significantly increased risk of death, and early risk stratification may help to choose the appropriate treatment. The study aimed to develop a neural network model by using a genetic algorithm (GA) for the prediction of mortality in patients with...

journal_title：PeerJ

authors： Zhang Z

更新日期：2019-09-16 00:00:00

abstract：:Web-spinning spiders that inhabit stream channels are considered specialists of aquatic ecosystems and are major consumers of emerging aquatic insects, while other spider taxa are more commonly found in riparian forests and as a result may consume more terrestrial insects. To determine if there was a difference in spi...

journal_title：PeerJ

authors： Kelly SP,Cuevas E,Ramírez A

更新日期：2015-10-15 00:00:00

abstract：:Using hypothetical scenarios, we provided participants with potential opening statements to a conflict discussion that varied on I/you language and communicated perspective. Participants rated the likelihood that the recipient of the statement would react in a defensive manner. Using I-language and communicating persp...

journal_title：PeerJ

authors： Rogers SL,Howieson J,Neame C

更新日期：2018-05-18 00:00:00

abstract：:Dorsal horn neurons in the spinal cord integrate and relay sensory information to higher brain centers. These neurons are organized in specific laminae and different transcription factors are involved in their specification. The murine homeodomain Gbx1 protein is expressed in the mantle zone of the spinal cord at E12....

journal_title：PeerJ

authors： Meziane H,Fraulob V,Riet F,Krezel W,Selloum M,Geffarth M,Acampora D,Hérault Y,Simeone A,Brand M,Dollé P,Rhinn M

更新日期：2013-08-29 00:00:00

abstract：:Background. There is growing awareness of the public health importance of mental well-being both in the general population and in specific groups. The well-being of health professionals is likely to influence the quality of the care they deliver. This study was carried out to examine the well-being of Pakistani health...

journal_title：PeerJ

authors： Waqas A,Ahmad W,Haddad M,Taggart FM,Muhammad Z,Bukhari MH,Sami SA,Batool SM,Najeeb F,Hanif A,Rizvi ZA,Ejaz S

更新日期：2015-10-01 00:00:00

abstract：:Metabarcoding can rapidly determine the species composition of bulk samples and thus aids biodiversity and ecosystem assessment. However, it is essential to use primer sets that minimize amplification bias among taxa to maximize species recovery. Despite this fact, the performance of primer sets employed for metabarco...

journal_title：PeerJ

authors： Elbrecht V,Braukmann TWA,Ivanova NV,Prosser SWJ,Hajibabaei M,Wright M,Zakharov EV,Hebert PDN,Steinke D

更新日期：2019-10-07 00:00:00

abstract：:Müller glia in the zebrafish retina respond to retinal damage by re-entering the cell cycle, which generates large numbers of retinal progenitors that ultimately replace the lost neurons. In this study we compared the regenerative outcomes of adult zebrafish exposed to one round of phototoxic treatment with adult zebr...

journal_title：PeerJ

authors： Ranski AH,Kramer AC,Morgan GW,Perez JL,Thummel R

更新日期：2018-09-20 00:00:00