Metabolomics window into the role of acute kidney injury after coronary artery bypass grafting in diabetic nephropathy progression.

abstract：Background:RNA sequencing is an indispensable research tool used in a broad range of transcriptome analysis studies. The most common application of RNA Sequencing is differential expression analysis and it is used to determine genetic loci with distinct expression across different conditions. An emerging field called s...

journal_title：PeerJ

authors： Dimitrov D,Gu Q

更新日期：2020-12-22 00:00:00

abstract：Background:"Quantile-dependent expressivity" occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g. adiponectin) is high or low relative to its distribution. We have previously shown that the heritability (h2 ) of adiposity, lipoproteins, postprandial lipemia, pulmonary function, and ...

journal_title：PeerJ

authors： Williams PT

更新日期：2020-10-14 00:00:00

abstract：:Cellulosic waste represents a significant and underutilized carbon source for the biofuel industry. Owing to the recalcitrance of crystalline cellulose to enzymatic degradation, it is necessary to design economical methods of liberating the fermentable sugars required for bioethanol production. One route towards unloc...

journal_title：PeerJ

authors： Hamberg Y,Ruimy-Israeli V,Dassa B,Barak Y,Lamed R,Cameron K,Fontes CM,Bayer EA,Fried DB

更新日期：2014-10-30 00:00:00

abstract：:Marine biodiversity and derived ecosystem services are critical to the healthy functioning of marine ecosystems, and to human economic and societal well-being. Thus, an understanding of marine biodiversity in different ecosystems is necessary for their conservation and management. Coral reefs in particular are noted f...

journal_title：PeerJ

authors： Reimer JD,Biondi P,Lau YW,Masucci GD,Nguyen XH,Santos MEA,Wee HB

更新日期：2019-04-12 00:00:00

abstract：Background:Medicare is one of the world's largest health insurance programs. It provides health insurance to nearly 44 million beneficiaries whose entitlements are based on age, disability, or end-stage renal disease (ESRD). Data of these ESRD beneficiaries are collected in the US Renal Data System (USRDS), which inclu...

journal_title：PeerJ

authors： Mu Y,Chin AI,Kshirsagar AV,Bang H

更新日期：2018-07-27 00:00:00

abstract：Background:Several authors have indicated that excess body weight can modify the electromyographic (EMG) amplitude due to the accumulation of subcutaneous fat. This accumulation of adipose tissue around the muscle would affect the metabolic capacity during functional activities. On the other hand, some authors have not...

journal_title：PeerJ

authors： Mendez-Rebolledo G,Guzman-Muñoz E,Ramírez-Campillo R,Valdés-Badilla P,Cruz-Montecinos C,Morales-Verdugo J,Berral de la Rosa FJ

更新日期：2019-06-25 00:00:00

abstract：:Staphylococcus aureus is a drug-resistant pathogen, capable of colonizing diverse ecological niches and causing a broad spectrum of infections related to a community and healthcare. In this study, we choose four methicillin-resistant S. aureus (MRSA) clinical isolates from Germany and Hungary based on our previous pol...

journal_title：PeerJ

authors： Naorem RS,Blom J,Fekete C

更新日期：2021-01-13 00:00:00

abstract：:Nephila clavata L Koch, known as the Joro spider and native to East Asia (Japan, China, Korea, and Taiwan), is newly reported from North America. Specimens from several locations in northeast Georgia were collected from around residential properties in Barrow, Jackson, and Madison counties in late October and early No...

journal_title：PeerJ

authors： Hoebeke ER,Huffmaster W,Freeman BJ

更新日期：2015-02-05 00:00:00

abstract：:In contrast to reports of wild primates, studies of captive primates' flexibility often reveal conservatism: individuals are unable to switch to new and more efficient strategies when task demands change. We propose that such conservatism might be a result of task design and hypothesize that conservatism might be link...

journal_title：PeerJ

authors： Jacobson SL,Hopper LM

更新日期：2019-01-08 00:00:00

abstract：:Abnormal behaviors in captive animals are generally defined as behaviors that are atypical for the species and are often considered to be indicators of poor welfare. Although some abnormal behaviors have been empirically linked to conditions related to elevated stress and compromised welfare in primates, others have l...

journal_title：PeerJ

authors： Jacobson SL,Ross SR,Bloomsmith MA

更新日期：2016-07-13 00:00:00

abstract：:Gammaherpesviruses (GHVs) are host specific DNA viruses that infect a large range of mammalian species. These viruses preferentially target host lymphocyte cell populations and infection may lead to morbidity or mortality in immunocompromised, co-infected, or non-adapted hosts. In this study, we tested for the presenc...

journal_title：PeerJ

authors： Loisel DA,Troyer RM,VandeWoude S

更新日期：2018-06-22 00:00:00

abstract：:Background. Nasal continuous positive airway pressure (nCPAP) is a widely accepted technique of non-invasive respiratory support in premature infants with respiratory distress syndrome due to lack of lung surfactant. If this approach fails, the next step is often intubation, mechanical ventilation (MV) and intratrache...

journal_title：PeerJ

authors： Walther FJ,Hernández-Juviel JM,Waring AJ

更新日期：2014-05-27 00:00:00

abstract：:Zoigê Plateau, China's largest plateau marsh wetland, has experienced large-scale degradation of the marsh wetland and evolution of the wetland landscape pattern over the past 40 years due to climate warming and human activities. How exactly do the wetland landscape pattern characteristics change? How do climatic chan...

journal_title：PeerJ

authors： Dong L,Yang W,Zhang K,Zhen S,Cheng X,Wu L

更新日期：2020-09-29 00:00:00

abstract：:Osteogenic cells form mineralized matrices in vitro, as well as in vivo. The formation and shape of the mineralized matrices are highly regulated by the cells. In vitro formation of mineralized matrices by osteogenic cells can be a model for in vivo osteogenesis. In this study, using a three-dimensional (3D) collagen ...

journal_title：PeerJ

authors： Kihara T,Umezu C,Sawada K,Furutani Y

更新日期：2019-10-23 00:00:00

abstract：Background:Among Buddhist or Taoist Taiwanese residents, burning incense is a common source of indoor particulate matter (PM), including PM10 and PM2.5, and can adversely affect the health status of patients with chronic obstructive pulmonary diseases (COPD). However, few studies have focused on the effects of intermit...

journal_title：PeerJ

authors： Guo SE,Chi MC,Lin CM,Yang TM

更新日期：2020-08-31 00:00:00

abstract：Background:Conserved nucleic acid sequences play an essential role in transcriptional regulation. The motifs/templates derived from nucleic acid sequence datasets are usually used as biomarkers to predict biochemical properties such as protein binding sites or to identify specific non-coding RNAs. In many cases, templa...

journal_title：PeerJ

authors： Peng H

更新日期：2020-04-20 00:00:00

abstract：:Bioluminescent reporter genes, such as those from fireflies and bacteria, let researchers use light production as a non-invasive and non-destructive surrogate measure of microbial numbers in a wide variety of environments. As bioluminescence needs microbial metabolites, tagging microorganisms with luciferases means on...

journal_title：PeerJ

authors： Read HM,Mills G,Johnson S,Tsai P,Dalton J,Barquist L,Print CG,Patrick WM,Wiles S

更新日期：2016-06-22 00:00:00

abstract：Background:Pandi's mushroom-tongue salamander (Bolitoglossa pandi) is one of the threatened amphibians in South America, as well as a flagship species for the Colombian conservation agenda. This species is endemic to the Andean cloud forests of the western slope of the Cordillera Oriental of Colombia, occurring only in...

journal_title：PeerJ

authors： Angarita-Sierra T,Bonilla-Gómez MA,Sánchez DA,Acosta-Galvis AR,Medina-Ovalle H,Solano-Moreno A,Ulloa-Rengifo S,Guevara-Guevara D,Torres-Ramirez JJ,Curaca-Fierro S,Cabrera-Amaya DM,Infante-Betancour JA,Londoño-Montaño LF,Albarán

更新日期：2020-09-24 00:00:00

abstract：:The aim of this study was to identify the facets influencing job satisfaction and intention to quit of nurses employed in Turkey. Using a non-probability sampling technique, 417 nurses from six large private hospitals were surveyed from March 2014 to June 2014. The nurses' demographic data, their job-related satisfact...

journal_title：PeerJ

authors： Masum AK,Azad MA,Hoque KE,Beh LS,Wanke P,Arslan Ö

更新日期：2016-04-26 00:00:00

abstract：:The Asian citrus psyllid (ACP), Diaphorina citri Kuwayama, is one of the most serious citrus pests worldwide due to its role as vector of huanglongbing or citrus greening disease. While some optimal plant species for ACP oviposition and development have been identified, little is known of the influence of host plants ...

journal_title：PeerJ

authors： Paris TM,Allan SA,Hall DG,Hentz MG,Hetesy G,Stansly PA

更新日期：2016-11-03 00:00:00

abstract：:Freshwater food webs are dominated by aquatic invertebrates whose trophic relationships are often poorly known. Here, I used laboratory experiments to study the role of a water bug, Sigara striata, as a potential predator and prey in food webs of stagnant waters. Multiple-choice predation experiment revealed that Siga...

journal_title：PeerJ

authors： Klecka J

更新日期：2014-05-22 00:00:00

abstract：:Sanderlings (Calidris alba) are long-distance migratory shorebirds with a non-breeding range that spans temperate and tropical coastal habitats. Breeding in the High Arctic combined with non-breeding seasons in the tropics necessitate long migrations, which are energetically demanding. On an annual basis, the higher e...

journal_title：PeerJ

authors： Grond K,Ntiamoa-Baidu Y,Piersma T,Reneerkens J

更新日期：2015-08-11 00:00:00

abstract：:Substantial evidence has shown that most exogenous substances are metabolized by multiple cytochrome P450 (P450) enzymes instead of by merely one P450 isoform. Thus, multi-P450 inhibition leads to greater drug-drug interaction risk than specific P450 inhibition. Herein, we innovatively established an artificial neural...

journal_title：PeerJ

authors： Li Z,Li Y,Sun L,Tang Y,Liu L,Zhu W

更新日期：2015-12-21 00:00:00

abstract：:Apis cerana cerana relies on its sensitive olfactory system to perform foraging activities in the surrounding environment. Olfactory receptors (ORs) are a primary requirement for odorant recognition and coding. However, the molecular recognition of volatile compounds with ORs in A. cerana cerana is still not clear. He...

journal_title：PeerJ

authors： Guo L,Zhao H,Jiang Y

更新日期：2018-06-11 00:00:00

abstract：:The hydrological connectivity between the salt marsh and the sea was partially restored in a Mediterranean wetland containing isolated ponds resulting from former salt extraction and aquaculture activities. A preliminary assessment provided evidence that ponds farther from the sea hosted very large numbers of the enda...

journal_title：PeerJ

authors： Prado P,Alcaraz C,Jornet L,Caiola N,Ibáñez C

更新日期：2017-02-28 00:00:00

abstract：:Current ovarian cancer treatment involves chemotherapy that has serious limitations, such as rapid clearance, unfavorable biodistribution and severe side effects. To overcome these limitations, drug delivery systems (DDS) have been developed to encapsulate chemotherapeutics for delivery to tumor cells. However, no sys...

journal_title：PeerJ

authors： Raavé R,de Vries RB,Massuger LF,van Kuppevelt TH,Daamen WF

更新日期：2015-12-10 00:00:00

abstract：:Wild edible mushrooms have been collected and consumed by human groups for centuries, and today they represent a relevant source of food and income for many rural families worldwide. Preserving these non-timber forest products is of great interest, and there is concern about the damage caused by intensive mushroom har...

journal_title：PeerJ

authors： Ruiz-Almenara C,Gándara E,Gómez-Hernández M

更新日期：2019-12-18 00:00:00

abstract：:In highly biodiverse systems, such as coral reefs, prey species are faced with predatory threats from numerous species. Recognition of predators can be innate, or learned, and can help increase the chance of survival. Research suggests that parental exposure to increased predatory threats can affect the development, b...

journal_title：PeerJ

authors： Atherton JA,McCormick MI

更新日期：2020-06-18 00:00:00

abstract：:Convergent evolution can provide insights into the predictability of, and constraints on, the evolution of biodiversity. One striking example of convergence is seen in the 'river dolphins'. The four dolphin genera that make up the 'river dolphins' (Inia geoffrensis, Pontoporia blainvillei, Platanista gangetica and Lip...

journal_title：PeerJ

authors： Page CE,Cooper N

更新日期：2017-11-21 00:00:00

abstract：:Helicobacter pylori is a human pathogenic bacterium with a high genomic plasticity. Although the functional CRISPR-Cas system has not been found in its genome, CRISPR-like loci have been recently identified. In this work, 53 genomes from different geographical areas are analyzed for the search and analysis of variabil...

journal_title：PeerJ

authors： García-Zea JA,de la Herrán R,Robles Rodríguez F,Navajas-Pérez R,Ruiz Rejón C

更新日期：2019-01-11 00:00:00