Identification of key genes in non-small cell lung cancer by bioinformatics analysis.

abstract：:Background. In recent years, there has been an explosion in the number of technical and medical diagnostic platforms being developed. This has greatly improved our ability to more accurately, and more comprehensively, explore and characterize human biological systems on the individual level. Large quantities of biomed...

journal_title：PeerJ

authors： O'Rawe JA,Fang H,Rynearson S,Robison R,Kiruluta ES,Higgins G,Eilbeck K,Reese MG,Lyon GJ

更新日期：2013-10-03 00:00:00

abstract：:Palythoa caribaeorum is a zoanthid often dominant in shallow rocky environments along the west coast of the Atlantic Ocean, from the tropics to the subtropics. This species has high environmental tolerance and is a good space competitor in reef environments. Considering current and future scenarios in the global clima...

journal_title：PeerJ

authors： Durante LM,Cruz ICS,Lotufo TMC

更新日期：2018-05-17 00:00:00

abstract：:Grazing and litter removal can alter understory structure and composition after afforestation, posing a serious threat to sustainable forest development. Enclosure is considered to be an effective measure to restore degraded forest restoration. However, little is known about the dynamics of soil nutrients and microbia...

journal_title：PeerJ

authors： Deng J,Zhou Y,Zhu W,Yin Y

更新日期：2020-03-25 00:00:00

abstract：OBJECTIVES:The purpose of this study is to determine the prevalence and clinical impact of human papillomavirus (HPV) related laryngeal squamous cell carcinoma (LSCC). METHODS:A total of 106 LSCC patients who underwent primary surgical resection with or without adjuvant radiotherapy/chemoradiotherapy were enrolled ret...

journal_title：PeerJ

authors： Chen WC,Chuang HC,Lin YT,Huang CC,Chien CY

更新日期：2017-05-30 00:00:00

abstract：:We used qingbo (Spinibarbus sinensis) and Chinese crucian carp (Carassius auratus) to test whether numerical discrimination could be improved by the coexistence and possible cooperation of conspecies or heterospecies. We conducted a spontaneous shoal choice test of singletons, conspecific dyads and heterospecific dyad...

journal_title：PeerJ

authors： Xiong W,Yi LC,Tang ZH,Fu SJ

更新日期：2019-03-11 00:00:00

abstract：Background:RNA sequencing is an indispensable research tool used in a broad range of transcriptome analysis studies. The most common application of RNA Sequencing is differential expression analysis and it is used to determine genetic loci with distinct expression across different conditions. An emerging field called s...

journal_title：PeerJ

authors： Dimitrov D,Gu Q

更新日期：2020-12-22 00:00:00

abstract：:Mechanical ventilation (MV) of patients can cause damage to bronchoalveolar epithelium, leading to a sterile inflammatory response, infection and in severe cases sepsis. Limited knowledge is available on the effects of MV on the innate immune defense system in the human lung. In this study, we demonstrate that cyclic ...

journal_title：PeerJ

authors： Karadottir H,Kulkarni NN,Gudjonsson T,Karason S,Gudmundsson GH

更新日期：2015-12-07 00:00:00

abstract：:Limestone karsts of Southeast Asia can harbor high levels of endemism, but are highly fragmented, increasingly threatened, and their biodiversity is often poorly studied. This is true of the Padawan Limestone Area of Sarawak, Malaysia, home to the endemic Artocarpus annulatus, the closest known wild relative of two im...

journal_title：PeerJ

authors： Dickinson L,Noble H,Gardner E,Puad ASA,Zakaria WNFW,Zerega NJC

更新日期：2020-09-21 00:00:00

abstract：:Purple Broccoli (Brassica oleracea L. var italica) attracts growing attention as a functional food. Its purple coloration is due to high anthocyanin amounts. Light represents a critical parameter affecting anthocyanins biosynthesis. In this study, 'Purple Broccoli', a light-responding pigmentation cultivar, was assess...

journal_title：PeerJ

authors： Liu C,Yao X,Li G,Huang L,Xie Z

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:With their Pan-American distribution, long-nosed armadillos (genus Dasypus) constitute an understudied model for Neotropical biogeography. This genus currently comprises seven recognized species, the nine-banded armadillo (D. novemcinctus) having the widest distribution ranging from Northern Argentina to the...

journal_title：PeerJ

authors： Billet G,Hautier L,de Thoisy B,Delsuc F

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:Invasive species are among the most significant threats to biodiversity. The diet of invasive animal populations is a crucial factor that must be considered in the context of biological invasions. A broad dietary spectrum is a frequently cited characteristic of invasive species, allowing them to thrive in a ...

journal_title：PeerJ

authors： Courant J,Vogt S,Marques R,Measey J,Secondi J,Rebelo R,De Villiers A,Ihlow F,De Busschere C,Backeljau T,Rödder D,Herrel A

更新日期：2017-05-16 00:00:00

abstract：:Background. Physical activity is important for children's physical, mental, and social well-being. Outdoor active play is an important yet unstudied domain of children's physical activity. The objective of this study was to determine if parental encouragement is associated with the frequency that children engage in ou...

journal_title：PeerJ

authors： Ferrao T,Janssen I

更新日期：2015-11-30 00:00:00

abstract：:Background. Recurrent pain is a common experience in childhood, but only few children with recurrent pain attend a physician. Previous studies yielded conflicting findings with regard to predictors of health care utilization in children with recurrent pain. Methods. The present study analyzes data from the German Heal...

journal_title：PeerJ

authors： Hirschfeld G,Wager J,Zernikow B

更新日期：2015-04-28 00:00:00

abstract：BACKGROUND:Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper understanding of genomic data, the CardioTF database was constructed. The...

journal_title：PeerJ

authors： Zhen Y

更新日期：2016-08-23 00:00:00

abstract：:The recent publication of a number of high resolution bacterial voltage-gated sodium channel structures has opened the door for the mechanisms employed by these channels to distinguish between ions to be elucidated. The way these channels select between Na(+) and K(+) has been investigated in computational studies, bu...

journal_title：PeerJ

authors： Corry B

更新日期：2013-02-12 00:00:00

abstract：:Apis cerana cerana relies on its sensitive olfactory system to perform foraging activities in the surrounding environment. Olfactory receptors (ORs) are a primary requirement for odorant recognition and coding. However, the molecular recognition of volatile compounds with ORs in A. cerana cerana is still not clear. He...

journal_title：PeerJ

authors： Guo L,Zhao H,Jiang Y

更新日期：2018-06-11 00:00:00

abstract：:To investigate community shelter effects of two invasive decapod species, Hemigrapsus sanguineus and Carcinus maenas, in the Long Island Sound (LIS), we deployed artificial shelters in the intertidal and immediate subtidal zones. These consisted of five groups during the summer: a control, a resident H. sanguineus mal...

journal_title：PeerJ

authors： Hudson DM,Reagan D,Crivello JF

更新日期：2016-07-27 00:00:00

abstract：Background:The influenza virus can cause seasonal infections with mild to severe symptoms, circulating worldwide, and it can affect people in any age group. Therefore, this infection is a serious public health problem that causes severe illness and death in high-risk populations. Every year, 0.5% of the world's populat...

journal_title：PeerJ

authors： Silva T,S Salomon P,Hamerski L,Walter J,B Menezes R,Siqueira JE,Santos A,Santos JAM,Ferme N,Guimarães T,O Fistarol G,I Hargreaves P,Thompson C,Thompson F,Souza TM,Siqueira M,Miranda M

更新日期：2018-10-26 00:00:00

abstract：Background:Human population growth has led to biodiversity declines in tropical cities. While habitat loss and fragmentation have been the main drivers of urban biodiversity loss, man-made interventions to reduce health risks have also emerged as an unintentional threat. For instance, insecticide fogging to control mos...

journal_title：PeerJ

authors： Lee NSM,Clements GR,Ting ASY,Wong ZH,Yek SH

更新日期：2020-10-01 00:00:00

abstract：:Convergent evolution can provide insights into the predictability of, and constraints on, the evolution of biodiversity. One striking example of convergence is seen in the 'river dolphins'. The four dolphin genera that make up the 'river dolphins' (Inia geoffrensis, Pontoporia blainvillei, Platanista gangetica and Lip...

journal_title：PeerJ

authors： Page CE,Cooper N

更新日期：2017-11-21 00:00:00

abstract：:One of the major challenges of bone tissue engineering applications is to construct a fully vascularized implant that can adapt to hypoxic environments in vivo. The incorporation of proangiogenic factors into scaffolds is a widely accepted method of achieving this goal. Recently, the proangiogenic potential of mesench...

journal_title：PeerJ

authors： Xie H,Wang Z,Zhang L,Lei Q,Zhao A,Wang H,Li Q,Chen Z,Zhang W

更新日期：2016-05-19 00:00:00

abstract：Background:Humpback whales (Megaptera novaeangliae) are a widespread, vocal baleen whale best known for producing song, a complex, repetitive, geographically distinct acoustic signal sung by males, predominantly in a breeding context. Humpback whales worldwide also produce non-song vocalizations ("calls") throughout th...

journal_title：PeerJ

authors： Fournet MEH,Jacobsen L,Gabriele CM,Mellinger DK,Klinck H

更新日期：2018-07-30 00:00:00

abstract：:Eggplant (Solanum melongena L.) is an important vegetable cultivated in Asia, Africa and southern Europe and, following tomato and pepper, ranks as the third most important solanaceous vegetable crop. The Dof (DNA-binding with one finger) family is a group of plant-specific transcription factors that play important ro...

journal_title：PeerJ

authors： Wei Q,Wang W,Hu T,Hu H,Mao W,Zhu Q,Bao C

更新日期：2018-03-06 00:00:00

abstract：BACKGROUND:Individuals with unilateral lower limb amputation have a high risk of developing knee osteoarthritis (OA) in their intact limb as they age. This risk may be related to joint loading experienced earlier in life. We hypothesized that loading during walking would be greater in the intact limb of young US milita...

journal_title：PeerJ

authors： Miller RH,Krupenevich RL,Pruziner AL,Wolf EJ,Schnall BL

更新日期：2017-02-02 00:00:00

abstract：:Pseudomonas syringae is the most widespread bacterial pathogen in plants. Several strains of P. syringae produce a phytotoxin, coronatine (COR), which acts as a jasmonic acid mimic and inhibits plant defense responses and contributes to disease symptom development. In this study, we found that COR inhibits early defen...

journal_title：PeerJ

authors： Lee S,Ishiga Y,Clermont K,Mysore KS

更新日期：2013-02-12 00:00:00

abstract：:The monoamines serotonin and dopamine are important neuromodulators present in the central nervous system, known to be active regulators of social behaviour in fish as in other vertebrates. Our aim was to investigate the region-specific brain monoaminergic differences arising when individual cleaners face a client (mu...

journal_title：PeerJ

authors： de Abreu MS,Messias JPM,Thörnqvist PO,Winberg S,Soares MC

更新日期：2018-05-24 00:00:00

abstract：:Ephemeral rivers act as linear oases in drylands providing key resources to people and wildlife. However, not much is known about these rivers' sensitivities to human activities. We investigated the landscape-level determinants of riparian tree dieback along the Swakop River, a dammed ephemeral river in Namibia, focus...

journal_title：PeerJ

authors： Douglas CM,Mulligan M,Harrison XA,Henschel JR,Pettorelli N,Cowlishaw G

更新日期：2016-10-27 00:00:00

abstract：:Protoporphyrin (PP) and biliverdin (BV) give rise to the enormous diversity in avian egg coloration. Egg color serves several ecological purposes, including post-mating signaling and camouflage. Egg camouflage represents a major character of open-nesting birds which accomplish protection of their unhatched offspring a...

journal_title：PeerJ

authors： Wiemann J,Yang TR,Sander PN,Schneider M,Engeser M,Kath-Schorr S,Müller CE,Sander PM

更新日期：2017-08-29 00:00:00

abstract：:We present a new supertree method that enables rapid estimation of a summary tree on the scale of millions of leaves. This supertree method summarizes a collection of input phylogenies and an input taxonomy. We introduce formal goals and criteria for such a supertree to satisfy in order to transparently and justifiabl...

journal_title：PeerJ

authors： Redelings BD,Holder MT

更新日期：2017-03-01 00:00:00

abstract：:Transmissible gastroenteritis virus (TGEV), belonging to the coronaviridae family, is the key cause of the fatal diarrhea of piglets and results in many pathological processes. microRNAs (miRNAs) play a key role in the regulation of virus-induced apoptosis. During the process of apoptosis induced by TGEV infection in ...

journal_title：PeerJ

authors： Zhao X,Song X,Bai X,Fei N,Huang Y,Zhao Z,Du Q,Zhang H,Zhang L,Tong D

更新日期：2016-02-04 00:00:00