Abstract：
:The present study investigated the treatment and survival outcomes of patients with synchronous primary esophageal squamous cell carcinoma and gastric adenocarcinoma. The medical records of 10,783 patients with primary esophageal squamous cancer treated at our institution between 1995 and 2012 were retrospectively reviewed. Overall survival (OS) rates were calculated using the Kaplan-Meier method. The incidence was 0.38% (41/10,783). Of these 41 patients, 26 underwent curative surgery, ten received palliative chemotherapy or radiotherapy, and five received no treatment. The median OS of the surgery, palliative-therapy, and treatment-free groups was 17.1, 9.0, and 3.8 months, respectively. The 1-, 3-, 5-, and 10-year OS rates for the surgery group were 77%, 45%, 33%, and 19%, respectively. No significant differences in median OS were observed between the surgery group and the historical cohort of isolated esophageal cancer (n = 186) (17.1 vs. 21.0 months, P = 0.061) or isolated gastric cancer (n = 51) (17.1 vs. 28.9 months, P = 0.875), or between the palliative-therapy group and its corresponding historical cohort (n = 30) (9.0 vs. 8.3 months, P = 0.862). The survival outcomes of patients with synchronous primary esophageal squamous and gastric cancers were not worse than those of patients with isolated esophageal cancer or isolated gastric cancer.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Li X,Lin S,Zhang Y,Wang Hdoi
10.1038/srep13335subject
Has Abstractpub_date
2015-08-20 00:00:00pages
13335issn
2045-2322pii
srep13335journal_volume
5pub_type
杂志文章abstract：:Recent studies demonstrate that the invasion and metastasis of gastric cancer (GC) is closely associated with a multi-subunit vacuolar H+-ATPase (V-ATPase). Here we investigated the expression and role of the human ATP6V1A gene that encodes the catalytic subunit A of V-ATPase in GC. We found that ATP6V1A expression le...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03021-3
更新日期：2017-06-07 00:00:00
abstract：:The gene encoding the cytosolic β-glucosidase GBA3 shows pseudogenization due to a truncated allele (rs358231) that is polymorphic in humans. Since this enzyme is involved in the transformation of many plant β-glycosides, this particular case of gene loss may have been influenced by dietary adaptations during evolutio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68106-y
更新日期：2020-07-14 00:00:00
abstract：:Despite the importance of urban trees, their growth reaction to climate change and to the urban heat island effect has not yet been investigated with an international scope. While we are well informed about forest growth under recent conditions, it is unclear if this knowledge can be simply transferred to urban enviro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14831-w
更新日期：2017-11-13 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38797-z
更新日期：2019-02-19 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-62439-4
更新日期：2020-03-24 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-58227-9
更新日期：2020-01-24 00:00:00
abstract：:We propose a novel method to achieve tunable plasmon focusing in graphene/photonic-crystal hybrid structure exhibiting all-angle negative refraction at terahertz frequencies. A two-dimensional photonic crystal composed of a square lattice of dielectric rods is constructed on the substrate of a graphene sheet to provid...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41788
更新日期：2017-02-02 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章,meta分析
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更新日期：2017-04-06 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78014-w
更新日期：2020-12-03 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16649-y
更新日期：2017-11-27 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04058
更新日期：2014-02-11 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-09-29 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22983
更新日期：2016-03-10 00:00:00
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journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-32119-5
更新日期：2018-09-11 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69255-w
更新日期：2020-07-28 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03660
更新日期：2014-01-13 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38366
更新日期：2016-12-05 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13664-x
更新日期：2017-10-23 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
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更新日期：2020-03-31 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05084
更新日期：2014-05-28 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03396-3
更新日期：2017-06-07 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01432-w
更新日期：2017-05-03 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31232-9
更新日期：2018-09-10 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-57865-3
更新日期：2020-01-21 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39738-6
更新日期：2019-02-28 00:00:00
abstract：:Geographically diverse samples from strawberry exhibiting symptoms of Strawberry Green Petal (SbGP), periwinkle plants with virescence, and blackberry, blueberry, and raspberry plants displaying yellowing and inedible fruits, were assayed for the presence of phytoplasma DNA. PCR targeting the 16S rRNA-encoding gene an...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00895-1
更新日期：2017-04-19 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2020-11-30 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39222
更新日期：2017-01-04 00:00:00
abstract：:Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-borne bunyavirus, can cause a life-threatening hemorrhagic syndrome in humans but not in its animal host. The virus is widely distributed throughout southeastern Europe, the Middle East, Africa, and Asia. Disease management has proven difficult and there are no bro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44210-6
更新日期：2019-05-23 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05117
更新日期：2014-05-30 00:00:00
