Narrow genetic base shapes population structure and linkage disequilibrium in an industrial oilseed crop, Brassica carinata A. Braun.

Abstract:

:Ethiopian mustard (Brassica carinata A. Braun) is an emerging sustainable source of vegetable oil, in particular for the biofuel industry. The present study exploited genome assemblies of the Brassica diploids, Brassica nigra and Brassica oleracea, to discover over 10,000 genome-wide SNPs using genotype by sequencing of 620 B. carinata lines. The analyses revealed a SNP frequency of one every 91.7 kb, a heterozygosity level of 0.30, nucleotide diversity levels of 1.31 × 10-05, and the first five principal components captured only 13% molecular variation, indicating low levels of genetic diversity among the B. carinata collection. Genome bias was observed, with greater SNP density found on the B subgenome. The 620 lines clustered into two distinct sub-populations (SP1 and SP2) with the majority of accessions (88%) clustered in SP1 with those from Ethiopia, the presumed centre of origin. SP2 was distinguished by a collection of breeding lines, implicating targeted selection in creating population structure. Two selective sweep regions on B3 and B8 were detected, which harbour genes involved in fatty acid and aliphatic glucosinolate biosynthesis, respectively. The assessment of genetic diversity, population structure, and LD in the global B. carinata collection provides critical information to assist future crop improvement.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Khedikar Y,Clarke WE,Chen L,Higgins EE,Kagale S,Koh CS,Bennett R,Parkin IAP

doi

10.1038/s41598-020-69255-w

subject

Has Abstract

pub_date

2020-07-28 00:00:00

pages

12629

issue

1

issn

2045-2322

pii

10.1038/s41598-020-69255-w

journal_volume

10

pub_type

杂志文章
  • Urban conservation hotspots: predation release allows the grassland-specialist burrowing owl to perform better in the city.

    abstract::Although habitat transformation is one of the main causes of biodiversity loss, there are many examples of species successfully occupying and even proliferating in highly human-modified habitats such are the cities. Thus, there is an increasing interest in understanding the drivers favoring urban life for some species...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-03853-z

    authors: Rebolo-Ifrán N,Tella JL,Carrete M

    更新日期:2017-06-14 00:00:00

  • The Parkinson Disease gene SNCA: Evolutionary and structural insights with pathological implication.

    abstract::After Alzheimer, Parkinson's disease (PD) is the second most common neurodegenerative disorder. Alpha synuclein (SNCA) is deemed as a major component of Lewy bodies, a neuropathological feature of PD. Five point mutations in SNCA have been reported so far, responsible for autosomal dominant PD. This study aims to deci...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24475

    authors: Siddiqui IJ,Pervaiz N,Abbasi AA

    更新日期:2016-04-15 00:00:00

  • Design, transform and control of optical field in discrete optical system: an example.

    abstract::A discrete optical system can broaden the spatial distribution of the input light through optical coupling in array waveguides, just like diffraction in continuous media. Here, we theoretically demonstrate several kinds of control methods of optical field propagation in a discrete optical system, which is composed of ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05414-w

    authors: Deng H,Yuan Y,Yuan L

    更新日期:2017-07-12 00:00:00

  • The Shape of Native Plant Cellulose Microfibrils.

    abstract::Determining the shape of plant cellulose microfibrils is critical for understanding plant cell wall molecular architecture and conversion of cellulose into biofuels. Only recently has it been determined that these cellulose microfibrils are composed of 18 cellulose chains rather than 36 polymers arranged in a diamond-...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-32211-w

    authors: Kubicki JD,Yang H,Sawada D,O'Neill H,Oehme D,Cosgrove D

    更新日期:2018-09-18 00:00:00

  • Engineering of an angiogenic niche by perfusion culture of adipose-derived stromal vascular fraction cells.

    abstract::In vitro recapitulation of an organotypic stromal environment, enabling efficient angiogenesis, is crucial to investigate and possibly improve vascularization in regenerative medicine. Our study aims at engineering the complexity of a vascular milieu including multiple cell-types, a stromal extracellular matrix (ECM),...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-13882-3

    authors: Cerino G,Gaudiello E,Muraro MG,Eckstein F,Martin I,Scherberich A,Marsano A

    更新日期:2017-10-27 00:00:00

  • Jasmonic acid-related resistance in tomato mediates interactions between whitefly and whitefly-transmitted virus.

    abstract::The indirect interactions between insect vectors, such as whiteflies, and the viruses they transmit, such as begomoviruses, via host plants may produce a range of outcome depending on the species/strain of each of the three organisms involved, and the mechanisms underlying the variations are not well understood. Here,...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00692-w

    authors: Sun YC,Pan LL,Ying FZ,Li P,Wang XW,Liu SS

    更新日期:2017-04-03 00:00:00

  • AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair.

    abstract::Double-strand breaks (DSBs) are the most lethal DNA damages induced by ionising radiation (IR) and their efficient repair is crucial to limit genomic instability. The cellular DSB response after low IR doses is of particular interest but its examination requires the analysis of high cell numbers. Here, we present an a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-35660-5

    authors: Lengert N,Mirsch J,Weimer RN,Schumann E,Haub P,Drossel B,Löbrich M

    更新日期:2018-11-23 00:00:00

  • Comparative Analysis of Gene Expression Profiles of Human Dental Fluorosis and Kashin-Beck Disease.

    abstract::To explore the pathologies of Kashin-Beck disease (KBD) and KBD accompanied with dental fluorosis (DF), we conducted a comparative analysis of gene expression profiles. 12 subjects were recruited, including 4 KBD patients, 4 patients with KBD and DF and 4 healthy subjects. Genome-wide expression profiles from their pe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18519-z

    authors: Zhang Q,Ma J,Liu H,He D,Chen L,Wu H,Jiang H,Lu Q,Bai S

    更新日期:2018-01-09 00:00:00

  • Overlapping motifs on the herpes viral proteins ICP27 and ORF57 mediate interactions with the mRNA export adaptors ALYREF and UIF.

    abstract::The TREX complex mediates the passage of bulk cellular mRNA export to the nuclear export factor TAP/NXF1 via the export adaptors ALYREF or UIF, which appear to act in a redundant manner. TREX complex recruitment to nascent RNA is coupled with 5' capping, splicing and polyadenylation. Therefore to facilitate expression...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-33379-x

    authors: Tunnicliffe RB,Tian X,Storer J,Sandri-Goldin RM,Golovanov AP

    更新日期:2018-10-09 00:00:00

  • Effects of combining constraint-induced movement therapy and action-observation training on upper limb kinematics in children with unilateral cerebral palsy: a randomized controlled trial.

    abstract::Modified constraint-induced movement therapy (mCIMT) improves upper limb (UL) motor execution in unilateral cerebral palsy (uCP). As these children also show motor planning deficits, action-observation training (AOT) might be of additional value. Here, we investigated the combined value of AOT to mCIMT on UL kinematic...

    journal_title:Scientific reports

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/s41598-020-67427-2

    authors: Simon-Martinez C,Mailleux L,Jaspers E,Ortibus E,Desloovere K,Klingels K,Feys H

    更新日期:2020-06-26 00:00:00

  • Probabilistic Movement Models Show that Postural Control Precedes and Predicts Volitional Motor Control.

    abstract::Human motor skill learning is driven by the necessity to adapt to new situations. While supportive contacts are essential for many tasks, little is known about their impact on motor learning. To study the effect of contacts an innovative full-body experimental paradigm was established. The task of the subjects was to ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28455

    authors: Rueckert E,Čamernik J,Peters J,Babič J

    更新日期:2016-06-22 00:00:00

  • Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer.

    abstract::Bivalent (poised or paused) chromatin comprises activating and repressing histone modifications at the same location. This combination of epigenetic marks at promoter or enhancer regions keeps genes expressed at low levels but poised for rapid activation. Typically, DNA at bivalent promoters is only lowly methylated i...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep37393

    authors: Bernhart SH,Kretzmer H,Holdt LM,Jühling F,Ammerpohl O,Bergmann AK,Northoff BH,Doose G,Siebert R,Stadler PF,Hoffmann S

    更新日期:2016-11-23 00:00:00

  • Modeled changes of cerebellar activity in mutant mice are predictive of their learning impairments.

    abstract::Translating neuronal activity to measurable behavioral changes has been a long-standing goal of systems neuroscience. Recently, we have developed a model of phase-reversal learning of the vestibulo-ocular reflex, a well-established, cerebellar-dependent task. The model, comprising both the cerebellar cortex and vestib...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep36131

    authors: Badura A,Clopath C,Schonewille M,De Zeeuw CI

    更新日期:2016-11-02 00:00:00

  • Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones.

    abstract::Microtubule affinity regulating kinase 4 (MARK4) becomes a unique anti-cancer drug target as its overexpression is responsible for different types of cancers. In quest of novel, effective MARK4 inhibitors, some acridone derivatives were synthesized, characterized and evaluated for inhibitory activity against human MAR...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-38217-8

    authors: Voura M,Khan P,Thysiadis S,Katsamakas S,Queen A,Hasan GM,Ali S,Sarli V,Hassan MI

    更新日期:2019-02-08 00:00:00

  • Differentially expressed microRNAs between cattleyak and yak testis.

    abstract::Cattleyak are interspecific hybrids between cattle and yak, exhibiting the same prominent adaptability as yak and much higher performances than yak. However, male infertility of cattleyak resulted from spermatogenic arrest has greatly restricted their effective utilization in yak breeding. In past decades, much work h...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18607-0

    authors: Xu C,Wu S,Zhao W,Mipam T,Liu J,Liu W,Yi C,Shah MA,Yu S,Cai X

    更新日期:2018-01-12 00:00:00

  • Phase Diagram of Continuous Binary Nanoalloys: Size, Shape, and Segregation Effects.

    abstract::The phase diagrams of continuous binary nanoalloys are important in providing guidance for material designs and industrial applications. However, experimental determination of the nano-phase diagram is scarce since calorimetric measurements remain quite challenging at the nanoscale. Based on the size-dependent cohesiv...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41990

    authors: Cui M,Lu H,Jiang H,Cao Z,Meng X

    更新日期:2017-02-07 00:00:00

  • Vegetation Greening and Climate Change Promote Multidecadal Rises of Global Land Evapotranspiration.

    abstract::Recent studies showed that anomalous dry conditions and limited moisture supply roughly between 1998 and 2008, especially in the Southern Hemisphere, led to reduced vegetation productivity and ceased growth in land evapotranspiration (ET). However, natural variability of Earth's climate system can degrade capabilities...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep15956

    authors: Zhang K,Kimball JS,Nemani RR,Running SW,Hong Y,Gourley JJ,Yu Z

    更新日期:2015-10-30 00:00:00

  • Tall fescue sward structure affects the grazing process of sheep.

    abstract::The study of factors influencing animal intake can provide a better understanding of the dynamics of the pasture ecosystem and serve as a basis for managing livestock in a more efficient way. We measured different sward surface heights of tall fescue in the process of short-term intake rate of sheep. There was a signi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-68827-0

    authors: Szymczak LS,de Moraes A,Sulc RM,Monteiro ALG,Lang CR,Moraes RF,da Silva DFF,Bremm C,de Faccio Carvalho PC

    更新日期:2020-07-16 00:00:00

  • Arterial Remodeling in B-Type Natriuretic Peptide Knock-Out Females.

    abstract::Sexual dimorphisms are recognized in cardiovascular conditions such as hypertension, stroke, thrombosis and vasculitis. B-type natriuretic peptide (BNP) is a guanylyl cyclase A (GC-A) agonist. The anti-hypertensive, vasodilatory, anti-fibrotic, and anti-hypertrophic properties of BNP are well established in male anima...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25623

    authors: Holditch SJ,Schreiber CA,Burnett JC,Ikeda Y

    更新日期:2016-05-10 00:00:00

  • Identification of circulating microRNAs during the liver neoplastic process in a murine model of hereditary tyrosinemia type 1.

    abstract::Hereditary tyrosinemia type 1 (HT1) is a severe inborn error of metabolism, impacting the tyrosine catabolic pathway with a high incidence of hepatocellular carcinoma (HCC). Using a HT1 murine model, we investigated the changes in profiles of circulating and hepatic miRNAs. The aim was to determine if plasma miRNAs co...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep27464

    authors: Angileri F,Morrow G,Scoazec JY,Gadot N,Roy V,Huang S,Wu T,Tanguay RM

    更新日期:2016-06-10 00:00:00

  • Different protein-protein interface patterns predicted by different machine learning methods.

    abstract::Different types of protein-protein interactions make different protein-protein interface patterns. Different machine learning methods are suitable to deal with different types of data. Then, is it the same situation that different interface patterns are preferred for prediction by different machine learning methods? H...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16397-z

    authors: Wang W,Yang Y,Yin J,Gong X

    更新日期:2017-11-22 00:00:00

  • Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations.

    abstract::The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to characterize the effects of spaceflight and reentry to 1 g on the structure and integrity of the retina and blood-retinal barrier (BRB) in the eye. To ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44696-0

    authors: Mao XW,Nishiyama NC,Byrum SD,Stanbouly S,Jones T,Drew A,Sridharan V,Boerma M,Tackett AJ,Zawieja D,Willey JS,Delp M,Pecaut MJ

    更新日期:2019-06-03 00:00:00

  • Hyperreflective Foci in the Outer Retinal Layers as a Predictor of the Functional Efficacy of Ranibizumab for Diabetic Macular Edema.

    abstract::Anti-VEGF drugs are as the first-line therapies for diabetic macular edema (DME). In this study, we investigated the association between hyperreflective foci in the outer retinal layers and functional efficacy in DME patients who received intravitreal ranibizumab (IVR) injections. We retrospectively reviewed 77 eyes o...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-57646-y

    authors: Yoshitake T,Murakami T,Suzuma K,Dodo Y,Fujimoto M,Tsujikawa A

    更新日期:2020-01-21 00:00:00

  • Activation volume of selected liquid crystals in the density scaling regime.

    abstract::In this paper, we demonstrate and thoroughly analyze the activation volumetric properties of selected liquid crystals in the nematic and crystalline E phases in comparison with those reported for glass-forming liquids. In the analysis, we have employed and evaluated two entropic models (based on either total or config...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep42174

    authors: Grzybowski A,Urban S,Mroz S,Paluch M

    更新日期:2017-02-09 00:00:00

  • Prognostic relevance of programmed cell death 1 ligand 2 (PDCD1LG2/PD-L2) in patients with advanced stage colon carcinoma treated with chemotherapy.

    abstract::Colorectal cancer (CRC) is the leading cause of cancer-related mortality worldwide. Although the role of tumor programmed cell death 1 ligand 1 (PD-L1) in suppressing antitumor immunity has been validated in various malignances, the impact of PD-L2 (PD-L2/PDCD1LG2) within tumors remains elusive. Here, we examined tumo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-79419-3

    authors: Huang KC,Chiang SF,Chen TW,Chen WT,Yang PC,Ke TW,Chao KSC

    更新日期:2020-12-18 00:00:00

  • Altered Gut Microbiota Profiles in Sows and Neonatal Piglets Associated with Porcine Epidemic Diarrhea Virus Infection.

    abstract::Porcine epidemic diarrhea virus (PEDV) is a devastating cause of diarrhea in pigs worldwide. Most of studies have focused on molecular and pathogenic characterization of PEDV, whereas there were limited studies in understanding the role of gut microbiota (GM) in viral-associated diarrhea. Here, using the Illumina MiSe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17830-z

    authors: Song D,Peng Q,Chen Y,Zhou X,Zhang F,Li A,Huang D,Wu Q,Ye Y,He H,Wang L,Tang Y

    更新日期:2017-12-12 00:00:00

  • Men increase contributions to a public good when under sexual competition.

    abstract::Why humans cooperate in large groups and with non-kin remains a puzzle for researchers across the natural and social sciences. Investigating whether cooperation is sexually selected could contribute to an understanding of the evolution of human cooperation. Competition for access to mates could indeed select for coope...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep29819

    authors: Tognetti A,Dubois D,Faurie C,Willinger M

    更新日期:2016-07-14 00:00:00

  • Effects of Chikungunya virus immunity on Mayaro virus disease and epidemic potential.

    abstract::Mayaro virus (MAYV) causes an acute febrile illness similar to that produced by chikungunya virus (CHIKV), an evolutionary relative in the Semliki Forest virus complex of alphaviruses. MAYV emergence is typically sporadic, but recent isolations and outbreaks indicate that the virus remains a public health concern. Giv...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-56551-3

    authors: Webb EM,Azar SR,Haller SL,Langsjoen RM,Cuthbert CE,Ramjag AT,Luo H,Plante K,Wang T,Simmons G,Carrington CVF,Weaver SC,Rossi SL,Auguste AJ

    更新日期:2019-12-31 00:00:00

  • Propagation of optically tunable coherent radiation in a gas of polar molecules.

    abstract::Coherent, optically dressed media composed of two-level molecular systems without inversion symmetry are considered as all-optically tunable sources of coherent radiation in the microwave domain. A theoretical model and a numerical toolbox are developed to confirm the main finding: the generation of low-frequency radi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-74569-w

    authors: Gładysz P,Wcisło P,Słowik K

    更新日期:2020-10-19 00:00:00

  • Unraveling nonlinear electrophysiologic processes in the human visual system with full dimension spectral analysis.

    abstract::Natural sensory signals have nonlinear structures dynamically composed of the carrier frequencies and the variation of the amplitude (i.e., envelope). How the human brain processes the envelope information is still poorly understood, largely due to the conventional analysis failing to quantify it directly. Here, we us...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-53286-z

    authors: Nguyen KT,Liang WK,Lee V,Chang WS,Muggleton NG,Yeh JR,Huang NE,Juan CH

    更新日期:2019-11-15 00:00:00