Efficacy and safety of multimodal analgesic techniques for preventing chronic postsurgery pain under different surgical categories: a meta-analysis.

Abstract:

:The purpose of this meta-analysis was to compare the efficacy and safety of regional anesthesia to manage chronic postsurgery pain. A systematic search of PubMed, EmBase, and the Cochrane Central Register of Controlled Trials was performed to identify randomized controlled trials that focused on chronic pain frequency, analgesic consumption, and adverse effects under different surgical categories. We collected 21 trials assessing 1,980 patients for our meta-analysis. The summary of relative risks (RRs) and standard mean differences (SMDs) were calculated to measure the treatment effect of regional anesthesia. Results indicated that regional anesthesia significantly reduced the frequency of postsurgery pain (RR, 0.69; 95% confidence interval [CI], 0.56-0.85; p < 0.001). The results showed significant differences in overall patient satisfaction between applications with and without regional anesthesia (SMD, 1.95; 95%CI, 0.83-3.06; p = 0.001); however in other results, there were no significant differences between the two groups. Subgroup analysis suggested that regional anesthesia treatment might differ according to country. In conclusion, our study indicated that regional anesthesia was effective and safe in reducing the frequency of postsurgery pain and improved overall patient satisfaction; however, studies on the long-term efficacy and safety of regional anesthesia are still required to further confirm these findings.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Zhou J,Fan Y,Zhong J,Wen X,Chen H

doi

10.1038/s41598-017-00813-5

subject

Has Abstract

pub_date

2017-04-06 00:00:00

pages

678

issue

1

issn

2045-2322

pii

10.1038/s41598-017-00813-5

journal_volume

7

pub_type

杂志文章,meta分析
  • Community phylogenetic structure reveals the imprint of dispersal-related dynamics and environmental filtering by nutrient availability in freshwater diatoms.

    abstract::Despite important progress, uncertainty persists regarding the ecological forces driving microbial community assembly. Here, we present the first study to use phylogenetic information to interpret the structure and diversity of diatom communities. We examined local phylogenetic divergence and beta- phylogenetic divers...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-48125-0

    authors: Keck F,Kahlert M

    更新日期:2019-08-12 00:00:00

  • Age-dependent decline in stress response capacity revealed by proteins dynamics analysis.

    abstract::The aging process is regarded as the progressive loss of physiological integrity, leading to impaired biological functions and the increased vulnerability to death. Among various biological functions, stress response capacity enables cells to alter gene expression patterns and survive when facing internal and external...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-72167-4

    authors: Chen K,Shen W,Zhang Z,Xiong F,Ouyang Q,Luo C

    更新日期:2020-09-16 00:00:00

  • The G-quadruplex fluorescent probe 3,6-bis(1-methyl-2-vinyl-pyridinium) carbazole diiodide as a biosensor for human cancers.

    abstract::Using time-gated fluorescence lifetime imaging microscopy, significantly more signals from 3,6-bis(1-methyl-2-vinyl-pyridinium) carbazole diiodide (o-BMVC) foci, characterized by the longer fluorescent decay time of o-BMVC, were detected in six types of cancer cells than in three types of normal cells. Accumulating ev...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-34378-8

    authors: Tseng TY,Chen WW,Chu IT,Wang CL,Chang CC,Lin MC,Lou PJ,Chang TC

    更新日期:2018-10-31 00:00:00

  • Evaluating the potential of endothelial cells derived from human induced pluripotent stem cells to form microvascular networks in 3D cultures.

    abstract::A major translational challenge in the fields of therapeutic angiogenesis and regenerative medicine is the need to create functional microvasculature. The purpose of this study was to assess whether a potentially autologous endothelial cell (EC) source derived from human induced pluripotent stem cells (iPSC-ECs) can f...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-20966-1

    authors: Bezenah JR,Kong YP,Putnam AJ

    更新日期:2018-02-08 00:00:00

  • Βeta 2-glycoprotein I protects mice against gram-negative septicaemia in a sexually dimorphic manner.

    abstract::The immune responses of males and females to bacterial infections display differences. The mechanisms that underlie this sexual dimorphism are multifactorial. Lipopolysaccharide (LPS) contributes to the pathogenesis of endotoxaemia. We have previously demonstrated that the plasma protein beta-2 glycoprotein-1 (β2GPI) ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-07945-8

    authors: El-Assaad F,Qi M,Gordon AK,Qi J,Dong S,Passam F,Weaver JC,Giannakopoulos B,Krilis SA

    更新日期:2017-08-15 00:00:00

  • Inhibitory effects of magnolol and honokiol on human calcitonin aggregation.

    abstract::Amyloid formation is associated with multiple amyloidosis diseases. Human calcitonin (hCT) is a typical amyloidogenic peptide, its aggregation is associated with medullary carcinoma of the thyroid (MTC), and also limits its clinical application. Magnolia officinalis is a traditional Chinese herbal medicine; its two ma...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep13556

    authors: Guo C,Ma L,Zhao Y,Peng A,Cheng B,Zhou Q,Zheng L,Huang K

    更新日期:2015-09-01 00:00:00

  • DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression.

    abstract::The DEAD-box RNA helicase DDX3 plays divergent roles in tumorigenesis, however, its function in mitosis is unclear. Immunofluorescence indicated that DDX3 localized to centrosome throughout the cell cycle and colocalized with centrosome-associated p53 during mitosis in HCT116 and U2OS cells. DDX3 depletion promoted ch...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-09779-w

    authors: Chen WJ,Wang WT,Tsai TY,Li HK,Lee YW

    更新日期:2017-08-25 00:00:00

  • RNA sequencing reveals a transcriptomic portrait of human mesenchymal stem cells from bone marrow, adipose tissue, and palatine tonsils.

    abstract::Human mesenchymal stem cells (MSCs) are adult multipotent cells that have plasticity and inhabit the stroma of diverse tissues. The potential utility of MSCs has been heavily investigated in the fields of regenerative medicine and cell therapy. However, MSCs represent diverse populations that may depend on the tissue ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16788-2

    authors: Cho KA,Park M,Kim YH,Woo SY,Ryu KH

    更新日期:2017-12-07 00:00:00

  • Fabrication of Ni-Ti-O nanotube arrays by anodization of NiTi alloy and their potential applications.

    abstract::Nickel-titanium-oxide (Ni-Ti-O) nanotube arrays (NTAs) prepared on nearly equiatomic NiTi alloy shall have broad application potential such as for energy storage and biomedicine, but their precise structure control is a great challenge because of the high content of alloying element of Ni, a non-valve metal that canno...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07547

    authors: Hang R,Liu Y,Zhao L,Gao A,Bai L,Huang X,Zhang X,Tang B,Chu PK

    更新日期:2014-12-18 00:00:00

  • Engineering of Baeyer-Villiger monooxygenase-based Escherichia coli biocatalyst for large scale biotransformation of ricinoleic acid into (Z)-11-(heptanoyloxy)undec-9-enoic acid.

    abstract::Baeyer-Villiger monooxygenases (BVMOs) are able to catalyze regiospecific Baeyer-Villiger oxygenation of a variety of cyclic and linear ketones to generate the corresponding lactones and esters, respectively. However, the enzymes are usually difficult to express in a functional form in microbial cells and are rather u...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28223

    authors: Seo JH,Kim HH,Jeon EY,Song YH,Shin CS,Park JB

    更新日期:2016-06-17 00:00:00

  • Association between sea lice (Lepeophtheirus salmonis) infestation on Atlantic salmon farms and wild Pacific salmon in Muchalat Inlet, Canada.

    abstract::Growth in salmon aquaculture over the past two decades has raised concerns regarding the potential impacts of the industry on neighboring ecosystems and wild fish productivity. Despite limited evidence, sea lice have been identified as a major cause for the decline in some wild Pacific salmon populations on the west c...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-22458-8

    authors: Nekouei O,Vanderstichel R,Thakur K,Arriagada G,Patanasatienkul T,Whittaker P,Milligan B,Stewardson L,Revie CW

    更新日期:2018-03-05 00:00:00

  • In-situ Liquid Phase Epitaxy: Another Strategy to Synthesize Heterostructured Core-shell Composites.

    abstract::Core-shell Nb2O5/TiO2 composite with hierarchical heterostructure is successfully synthesized In-situ by a facile template-free and acid-free solvothermal method based on the mechanism of liquid phase epitaxy. The chemical circumstance change induced by the alcoholysis of NbCl5 is utilized tactically to trigger core-s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25260

    authors: Wen Z,Wang G

    更新日期:2016-04-28 00:00:00

  • Broadband and wide field-of-view plasmonic metasurface-enabled waveplates.

    abstract::Quasi two-dimensional metasurfaces composed of subwavelength nanoresonator arrays can dramatically alter the properties of light in an ultra-thin planar geometry, enabling new optical functions such as anomalous reflection and refraction, polarization filtering, and wavefront modulation. However, previous metasurface-...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07511

    authors: Jiang ZH,Lin L,Ma D,Yun S,Werner DH,Liu Z,Mayer TS

    更新日期:2014-12-19 00:00:00

  • Perovskite LaFeO3/montmorillonite nanocomposites: synthesis, interface characteristics and enhanced photocatalytic activity.

    abstract::Perovskite LaFeO3/montmorillonite nanocomposites (LaFeO3/MMT) have been successfully prepared via assembling LaFeO3 nanoparticles on the surface of montmorillonite with citric acid assisted sol-gel method. The results indicated that the uniform LaFeO3 nanoparticles were densely deposited onto the surface of montmorill...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19723

    authors: Peng K,Fu L,Yang H,Ouyang J

    更新日期:2016-01-18 00:00:00

  • Directed differentiation of human induced pluripotent stem cells into mature stratified bladder urothelium.

    abstract::For augmentation or reconstruction of urinary bladder after cystectomy, bladder urothelium derived from human induced pluripotent stem cells (hiPSCs) has recently received focus. However, previous studies have only shown the emergence of cells expressing some urothelial markers among derivatives of hiPSCs, and no repo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-46848-8

    authors: Suzuki K,Koyanagi-Aoi M,Uehara K,Hinata N,Fujisawa M,Aoi T

    更新日期:2019-07-19 00:00:00

  • The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.

    abstract::Clinicians often hesitate prescribing corticosteroids to treat corticosteroid-responsive conditions in sickle cell disease (SCD) patients because their use can be associated with complications (increased hospital readmission, rebound pain, strokes, avascular necrosis, acute chest syndrome). Consequently, SCD patients ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-24274-6

    authors: Almeida LEF,Damsker JM,Albani S,Afsar N,Kamimura S,Pratt D,Kleiner DE,Quezado M,Gordish-Dressman H,Quezado ZMN

    更新日期:2018-04-17 00:00:00

  • Dynamic representation of time in brain states.

    abstract::The ability to process time on the scale of milliseconds and seconds is essential for behaviour. A growing number of studies have started to focus on brain dynamics as a mechanism for temporal encoding. Although there is growing evidence in favour of this view from computational and in vitro studies, there is still a ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep46053

    authors: Bueno FD,Morita VC,de Camargo RY,Reyes MB,Caetano MS,Cravo AM

    更新日期:2017-04-10 00:00:00

  • In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging.

    abstract::Macrophage infiltration and recruitment in breast tumors has been correlated with poor prognosis in breast cancer patients and has been linked to tumor cell dissemination. Much of our understanding comes from animal models in which macrophages are labeled by expression of an extrinsic fluorophore. However, conventiona...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25086

    authors: Szulczewski JM,Inman DR,Entenberg D,Ponik SM,Aguirre-Ghiso J,Castracane J,Condeelis J,Eliceiri KW,Keely PJ

    更新日期:2016-05-25 00:00:00

  • Individual, but not population asymmetries, are modulated by social environment and genotype in Drosophila melanogaster.

    abstract::Theory predicts that social interactions can induce an alignment of behavioral asymmetries between individuals (i.e., population-level lateralization), but evidence for this effect is mixed. To understand how interaction with other individuals affects behavioral asymmetries, we systematically manipulated the social en...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-61410-7

    authors: Versace E,Caffini M,Werkhoven Z,de Bivort BL

    更新日期:2020-03-11 00:00:00

  • Optimization of neuronal cultures from rat superior cervical ganglia for dual patch recording.

    abstract::Superior cervical ganglion neurons (SCGN) are often used to investigate neurotransmitter release mechanisms. In this study, we optimized the dissociation and culture conditions of rat SCGN cultures for dual patch clamp recordings. Two weeks in vitro are sufficient to achieve a significant CNTF-induced cholinergic swit...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep14455

    authors: Amendola J,Boumedine N,Sangiardi M,El Far O

    更新日期:2015-09-24 00:00:00

  • A potent synthetic inorganic antibiotic with activity against drug-resistant pathogens.

    abstract::The acronymously named "ESKAPE" pathogens represent a group of bacteria that continue to pose a serious threat to human health, not only due to their propensity for repeated emergence, but also due to their ability to "eskape" antibiotic treatment. The evolution of multi-drug resistance in these pathogens alone has gr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41999

    authors: Hubick S,Jayaraman A,McKeen A,Reid S,Alcorn J,Stavrinides J,Sterenberg BT

    更新日期:2017-02-06 00:00:00

  • Corrigendum: SUV39H1 Reduction Is Implicated in Abnormal Inflammation in COPD.

    abstract::This corrects the article DOI: 10.1038/srep46667. ...

    journal_title:Scientific reports

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/srep46924

    authors: Chen TT,Wu SM,Ho SC,Chuang HC,Liu CY,Chan YF,Kuo LW,Feng PH,Liu WT,Chen KY,Hsiao TC,Juang JN,Lee KY

    更新日期:2017-12-22 00:00:00

  • Application of a convolutional neural network for predicting the occurrence of ventricular tachyarrhythmia using heart rate variability features.

    abstract::Predicting the occurrence of ventricular tachyarrhythmia (VTA) in advance is a matter of utmost importance for saving the lives of cardiac arrhythmia patients. Machine learning algorithms have been used to predict the occurrence of imminent VTA. In this study, we used a one-dimensional convolutional neural network (1-...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-63566-8

    authors: Taye GT,Hwang HJ,Lim KM

    更新日期:2020-04-21 00:00:00

  • mRNAs containing NMD-competent premature termination codons are stabilized and translated under UPF1 depletion.

    abstract::mRNAs containing premature termination codons (PTCs) are rapidly degraded through nonsense-mediated mRNA decay (NMD). However, some PTC-containing mRNAs evade NMD, and might generate mutant proteins responsible for various diseases, including cancers. Using PTC-containing human genomic β-globin constructs, we show tha...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16177-9

    authors: Kim WK,Yun S,Kwon Y,You KT,Shin N,Kim J,Kim H

    更新日期:2017-11-20 00:00:00

  • The corepressor NCOR1 regulates the survival of single-positive thymocytes.

    abstract::Nuclear receptor corepressor 1 (NCOR1) is a transcriptional regulator bridging repressive chromatin modifying enzymes with transcription factors. NCOR1 regulates many biological processes, however its role in T cells is not known. Here we show that Cd4-Cre-mediated deletion of NCOR1 (NCOR1 cKOCd4) resulted in a reduct...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-15918-0

    authors: Müller L,Hainberger D,Stolz V,Hamminger P,Hassan H,Preglej T,Boucheron N,Sakaguchi S,Wiegers GJ,Villunger A,Auwerx J,Ellmeier W

    更新日期:2017-11-21 00:00:00

  • Association between anemia and bronchopulmonary dysplasia in preterm infants.

    abstract::Anemia is commonly seen in preterm infants. It may reduce the capacity of hemoglobin to transport oxygen throughout the body and may result in tissue and organ dysfunction. This study aimed to investigate the effect of anemia on the development of bronchopulmonary dysplasia (BPD) in preterm infants. 243 infants who we...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章

    doi:10.1038/srep22717

    authors: Duan J,Kong X,Li Q,Hua S,Zhang S,Zhang X,Feng Z

    更新日期:2016-03-03 00:00:00

  • Probing Nanoscale Thermal Transport in Surfactant Solutions.

    abstract::Surfactant solutions typically feature tunable nanoscale, internal structures. Although rarely utilized, they can be a powerful platform for probing thermal transport in nanoscale domains and across interfaces with nanometer-size radius. Here, we examine the structure and thermal transport in solution of AOT (Dioctyl ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep16040

    authors: Cao F,Liu Y,Xu J,He Y,Hammouda B,Qiao R,Yang B

    更新日期:2015-11-04 00:00:00

  • Comparative transcriptional profiling of tildipirosin-resistant and sensitive Haemophilus parasuis.

    abstract::Numerous studies have been conducted to examine the molecular mechanism of Haemophilus parasuis resistance to antibiotic, but rarely to tildipirosin. In the current study, transcriptional profiling was applied to analyse the variation in gene expression of JS0135 and tildipirosin-resistant JS32. The growth curves show...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-07972-5

    authors: Lei Z,Fu S,Yang B,Liu Q,Ahmed S,Xu L,Xiong J,Cao J,Qiu Y

    更新日期:2017-08-08 00:00:00

  • Enhanced hot-carrier luminescence in multilayer reduced graphene oxide nanospheres.

    abstract::We report a method to promote photoluminescence emission in graphene materials by enhancing carrier scattering instead of directly modifying band structure in multilayer reduced graphene oxide (rGO) nanospheres. We intentionally curl graphene layers to form nanospheres by reducing graphene oxide with spherical polymer...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep02315

    authors: Chen Q,Zhang C,Xue F,Zhou Y,Li W,Wang Y,Tu W,Zou Z,Wang X,Xiao M

    更新日期:2013-01-01 00:00:00

  • 11,000 years of craniofacial and mandibular variation in Lower Nubia.

    abstract::The transition to agriculture was a key event in human history. The extent to which this transition is associated with biological changes in different world regions remains debated. Cultural and osteological records in Lower Nubia throughout the Holocene have been interpreted as a result of in situ differentiation or ...

    journal_title:Scientific reports

    pub_type: 历史文章,杂志文章

    doi:10.1038/srep31040

    authors: Galland M,Van Gerven DP,Von Cramon-Taubadel N,Pinhasi R

    更新日期:2016-08-09 00:00:00