TLR4-MyD88-TRAF6-TAK1 Complex-Mediated NF-κB Activation Contribute to the Anti-Inflammatory Effect of V8 in LPS-Induced Human Cervical Cancer SiHa Cells.

abstract：BACKGROUND:Accumulation of immune complexes in the mesangium is a common finding. Since migration of macrophages (Mphi) in the mesangium has been demonstrated to be an important event in the development of glomerular lesions, we studied the role of immune complexes and mesangial cell (MC) interaction in the transmigrat...

journal_title：Inflammation

authors： Singhal PC,Gupta S,Sharma P,Shah H,Shah N,Patel P

更新日期：2000-12-01 00:00:00

abstract：:Current knowledge implicates pleural mesothelial cells as mainly responsible for inflammatory responses in the pleural space. However, a vast body of recent evidence underscores the important role of fibroblasts in the process of inflammation in several types of tissues. We hypothesize that HPFBs (human pleural fibrob...

journal_title：Inflammation

authors： Loghmani F,Mohammed KA,Nasreen N,Van Horn RD,Hardwick JA,Sanders KL,Antony VB

更新日期：2002-04-01 00:00:00

abstract：:We aim to determine the extent of the CD40-CD40L pathway involvement in activated platelet-induced changes in human umbilical endothelial cells (HUVECs). Activated platelets were co-incubated with HUVECs in the presence or absence of CD40LmAb. HUVECs were also directly stimulated with rhCD40L. HUVEC endothelial cycloo...

journal_title：Inflammation

authors： Wu YQ,Chen XS,Chai JB

更新日期：2012-06-01 00:00:00

abstract：:The present study was designed to evaluate inflammatory changes in collapsed lungs during one-lung ventilation using the assistance of a bronchoscopic microsampling probe. Serial albumin and interleukin (IL)-8 concentrations in epithelial lining fluid (ELF) were measured in seven patients undergoing resection of lung ...

journal_title：Inflammation

authors： Komatsu Y,Yamamoto H,Tsushima K,Furuya S,Yoshikawa S,Yasuo M,Kubo K,Yamazaki Y,Hasegawa J,Eguchi T,Kondo R,Yoshida K,Koizumi T

更新日期：2012-12-01 00:00:00

abstract：:The purpose of the present study is to evaluate the effect of emu oil on bioavailability of curcumin when co-administered and to evaluate the property that enhances the anti-inflammatory potential of curcumin. Oral bioavailability of curcumin in combination with emu oil was determined by measuring the plasma concentra...

journal_title：Inflammation

authors： Jeengar MK,Shrivastava S,Nair K,Singareddy SR,Putcha UK,Talluri MV,Naidu VG,Sistla R

更新日期：2014-12-01 00:00:00

abstract：:The ability of peripheral blood neutrophils to injure elements of the alveolar septum was assessed. Experiments consisted of activating previously isolated neutrophils (PMNs) with a soluble (phorbol myristate acetate, PMA) and a particulate (zymosan) trigger, and measuring detachment of 51Cr-labeled epithelial cells. ...

journal_title：Inflammation

authors： Brown DM,Brown GM,Macnee W,Donaldson K

更新日期：1992-02-01 00:00:00

abstract：:Karyopherin-α2 (KPNA2) functions as an adaptor that transports several proteins to the nucleus. We investigated the function and possible mechanisms of KPNA2 involved in rheumatoid arthritis (RA). Western blotting and immunohistochemistry showed the protein expression of KPNA2 increased in synovial tissue of RA patien...

journal_title：Inflammation

authors： Liu Z,Zhang D,Sun C,Tao R,Xu X,Xu L,Cheng H,Xiao M,Wang Y

更新日期：2015-12-01 00:00:00

abstract：:Asthma is the most common chronic disease of childhood, chronic airway inflammation; bronchial tissue fibrosis, is a pathological feature common to children asthma, and an emerging data has indicted that autophagy plays critical roles in airway inflammation and fibrosis-mediated airway remodeling. The aim of this stud...

journal_title：Inflammation

authors： Li BB,Chen YL,Pang F

更新日期：2020-02-01 00:00:00

abstract：:Pyroptosis, a new pro-inflammatory programmed cell death, is linked to atherosclerosis (AS). Our previous studies suggested that salidroside (SAL) can alleviate AS and exert anti-oxidative and anti-inflammatory properties. However, the effect of SAL on atherosclerosis-related pyroptosis has not been studied. Here, we ...

journal_title：Inflammation

authors： Xing SS,Yang J,Li WJ,Li J,Chen L,Yang YT,Lei X,Li J,Wang K,Liu X

更新日期：2020-04-01 00:00:00

abstract：:Two different substances, glycogen and thioglycollate, were used to recruit early peritoneal exudate cells (4h). In the acute phase of the inflammatory response the cellular infiltrate is large, and the predominant cell (greater than 95%) is the polymorphonuclear neutrophil. Supernatant had differing effects on lympho...

journal_title：Inflammation

authors： Rodrick ML,Lamster IB,Sonis ST,Pender SG,Kolodkin AB,Fitzgerald JE,Wilson RE

更新日期：1982-03-01 00:00:00

abstract：:Berberine (Ber), the major constituent of Coptidis Rhizoma, possesses anti-inflammatory properties. In this study, we investigated the effects of Ber on cigarette smoke (CS)-mediated acute lung inflammation. C57BL/6 mice (6-8 weeks) were exposed to CS to induce acute lung injury. Ber was used to pretreat CS-exposed mi...

journal_title：Inflammation

authors： Lin K,Liu S,Shen Y,Li Q

更新日期：2013-10-01 00:00:00

abstract：:The original version of this article contained mistakes, and the authors would like to correct them. ...

journal_title：Inflammation

authors： Wang Y,Han CC,Cui D,Luo TT,Li Y,Zhang Y,Ma Y,Wei W

更新日期：2018-06-01 00:00:00

abstract：:Sepsis is a systemic inflammatory response syndrome caused by infection. The core mechanism underlying sepsis is immune dysfunction, with macrophages, as important cells of the innate immune system, playing an essential role. Autophagy has been shown to be closely related to inflammation and immunity, and autophagy en...

journal_title：Inflammation

authors： Qiu P,Liu Y,Zhang J

更新日期：2019-02-01 00:00:00

abstract：:C3b receptor (CR1) expression by neutrophils (PMNs) and erythrocytes (Es) from patients with chronic granulomatous disease (CGD) or with hyper-IgE, frequent infection (Job's) syndrome was compared with that of control subjects. The control subjects consisted of one group of patients with infections and a second group ...

journal_title：Inflammation

authors： Gaither TA,Gallin JI,Iida K,Nussenzweig V,Frank MM

更新日期：1984-12-01 00:00:00

abstract：:The aim of this study is to explore the dynamic changes in IL-17-expressing T cells (Th17)/Treg expression in monophasic experimental autoimmune uveitis (mEAU). mEAU was induced in Lewis rats with IRBP1177-1191 peptide and evaluated clinically and pathologically on days 9, 13, 18, 23, 28, 35, and 48. Lymphocytes isola...

journal_title：Inflammation

authors： Zhang L,Wan F,Song J,Tang K,Zheng F,Guo J,Guo D,Bi H

更新日期：2016-02-01 00:00:00

abstract：:Chemical alteration of the glucocorticoid, methylprednisolone, has led to the introduction of a new class of compounds called the 21-aminosteroids (21-ASs). The purpose of this study was to investigate the effect of the 21-AS, U74389G, on silica-induced acute lung injury. Male Fischer 344 rats were treated intraperito...

journal_title：Inflammation

authors： Antonini JM,van Dyke K,DiMatteo M,Reasor MJ

更新日期：1995-02-01 00:00:00

abstract：:The aim of our study was to evaluate the pro- and anti-inflammatory cytokine response during acute pancreatitis and its predictive value on severity of disease. A hospital-based prospective clinical study was conducted. Twenty patients with acute pancreatitis were enrolled during a 12-month period. Plasma concentratio...

journal_title：Inflammation

authors： Gunjaca I,Zunic J,Gunjaca M,Kovac Z

更新日期：2012-04-01 00:00:00

abstract：:Previous studies have suggested that Interleukin-6 (IL-6) acts as a marker of vasculitis. To determine the role of IL-6 in vasculitis we utilized two models of immune complex induced vascular injury (dermal Arthus and acute pulmonary alveolitis) in IL-6 deficient (IL-6(-/-)) and IL-6 sufficient (IL-6(+/+)) mice. Plasm...

journal_title：Inflammation

authors： McClintock SD,Barron AG,Olle EW,Deogracias MP,Warner RL,Opp M,Johnson KJ

更新日期：2005-12-01 00:00:00

abstract：:Thromboxane (Tx) A2 generation and subsequent selective pulmonary sequestration of neutrophils (PMNs) is characteristic of several forms of the adult respiratory distress syndrome (ARDS). Therefore, we examined PMN-dependent adhesion to cultured pulmonary microvessel and aortic endothelium (EC) in response to U46,619 ...

journal_title：Inflammation

authors： Wiles ME,Welbourn R,Goldman G,Hechtman HB,Shepro D

更新日期：1991-06-01 00:00:00

abstract：:The newly discovered gamma-PKC-related-protein of human leukocytes (gamma-rp) crossreacts with a polyclonal antibody preparation originally designed to be specific for PKC-gamma (gammaMb-Ab). As this antibody is currently the only suitable probe for gamma-rp, we sought to characterize the binding of the two proteins. ...

journal_title：Inflammation

authors： Smallwood JI,Malawista SE

更新日期：1999-08-01 00:00:00

abstract：:Systemic sclerosis (SSc) is a disease characterized by skin and internal organ involvement. There is progressive accumulation of extracellular matrix components in the skin and involved organs. Tissue fibrosis is the prominent reason for mortality, and still, there is no satisfactory treatment. The aim of this study w...

journal_title：Inflammation

authors： Demir T,Turkbeyler I,Kaplan DS,Pehlivan Y,Orkmez M,Tutar E,Taysi S,Kisacik B,Onat AM,Bagcı C

更新日期：2013-02-01 00:00:00

abstract：:Icariin is a flavonoid isolated from the traditional Chinese herbal medicine Epimedium brevicornum Maxim and has been reported to be effective for the treatment of a variety of cardiovascular diseases. The aim of the present study was to investigate the effect and mechanism of icariin on atherosclerosis (AS) using a h...

journal_title：Inflammation

authors： Hu Y,Sun B,Liu K,Yan M,Zhang Y,Miao C,Ren L

更新日期：2016-02-01 00:00:00

abstract：:By the use of the nuclear microprobe technique, the concentrations of zinc in isolated erythrocytes, platelets, and granulocytes were measured in patients with rheumatoid arthritis, other inflammatory arthritides, and scleroderma. Markedly reduced cellular zinc values were found compared to those measured in healthy s...

journal_title：Inflammation

authors： Svenson KL,Hällgren R,Johansson E,Lindh U

更新日期：1985-06-01 00:00:00

abstract：:The aim of this present study is to compare the effect of pressure-controlled ventilation and volume-controlled ventilation on pulmonary mechanics and inflammatory markers in prone position. The study included 41 patients undergoing to vertebrae surgery. The patients were randomized into two groups: Group 1 received v...

journal_title：Inflammation

authors： Şenay H,Sıvacı R,Kokulu S,Koca B,Bakı ED,Ela Y

更新日期：2016-08-01 00:00:00

abstract：:Induction of colitis by 2,4,6-Trinitrobenzenesulphonic acid (TNB) in the rat is a widely used experimental model of inflammatory bowel disease. Action of TNB as a hapten, induces colitis involving infiltration of colonic mucosa by neutrophils and macrophages and increased production of inflammatory mediators. The aim ...

journal_title：Inflammation

authors： Kankuri E,Asmawi MZ,Korpela R,Vapaatalo H,Moilanen E

更新日期：1999-04-01 00:00:00

abstract：:Activated macrophages exhibiting diverse phenotypes and various functions contribute to the pathogenesis or amelioration of different diseases like cancer, inflammation, and infectious and autoimmune diseases. However, the mechanisms of macrophage polarization in inflamed joint and its effects on rheumatoid arthritis ...

journal_title：Inflammation

authors： Dongsheng Z,Zhiguang F,Junfeng J,Zifan L,Li W

更新日期：2017-10-01 00:00:00

abstract：:Nicotine has anti- and pro-inflammatory properties in various cells. Its role in aortic vascular smooth muscle cells (VSMC) was explored. Human aortic VSMC were cultured. After nicotine (1.0 μM) and/or pyrrolidinedithiocarbamic acid (PDTC, 50 μM) treatment, the activation of nuclear factor κB (NFκB) was investigated. ...

journal_title：Inflammation

authors： Wang Y,Zhang F,Yang W,Xue S

更新日期：2012-02-01 00:00:00

abstract：:The existence of multiple-interactive roles between several signaling pathways in tumorigenesis shows the significance of pharmacological factors like heat shock protein 90 (HSP90) inhibitors which control several signaling pathways simultaneously. HSP90 as a molecular chaperone supports the active conformational stru...

journal_title：Inflammation

authors： Mohammadi A,Yaghoobi MM,Gholamhoseinian Najar A,Kalantari-Khandani B,Sharifi H,Saravani M

更新日期：2016-06-01 00:00:00

abstract：:The objective of this study was to investigate the effect of hyperlipidemia (HLP) on innate immune responses to lipopolysaccharide (LPS). Male New Zealand white rabbits were fed a normal diet (ND) or a high-fat diet (HFD) for 8 weeks. In vivo, the rabbits were injected intravenously with LPS for 24 h. In vitro, periph...

journal_title：Inflammation

authors： Chen S,Lin G,Lei L,You X,Wu C,Xu W,Huang M,Luo L,Wang Z,Li Y,Zhao X,Yan F

更新日期：2013-08-01 00:00:00

abstract：:The effect of leukocyte hydrolytic enzymes on periodontopathic bacteria was examined in vitro. A frozen and thawed extract of human peripheral blood leukocytes (LE) and human gingival crevicular exudate (GE) were shown to be able to cause the release of 50% of the radioactivity from a leukotoxic strain of Actinobacill...

journal_title：Inflammation

authors： Sela MN

更新日期：1983-06-01 00:00:00