High-resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers.

abstract：:A case-control study of 374 patients with primary epithelial cancers of the oral cavity, oro- and hypopharynx, and larynx is reported, the controls being patients with selected other cancers, matched for age and sex. Of all eligible patients, 93% were interviewed. Increased risks were seen with alcohol consumption and...

journal_title：International journal of cancer

authors： Elwood JM,Pearson JC,Skippen DH,Jackson SM

更新日期：1984-11-15 00:00:00

abstract：:Cancers occurring at the gastroesophageal junction (GEJ) are classified as predominantly esophageal or gastric, which is often difficult to decipher. We hypothesized that the transcriptomic profile might reveal molecular subgroups which could help to define the tumor origin and behavior beyond anatomical location. The...

journal_title：International journal of cancer

authors： Bornschein J,Wernisch L,Secrier M,Miremadi A,Perner J,MacRae S,O'Donovan M,Newton R,Menon S,Bower L,Eldridge MD,Devonshire G,Cheah C,Turkington R,Hardwick RH,Selgrad M,Venerito M,Malfertheiner P,OCCAMS Consortium.,F

更新日期：2019-12-15 00:00:00

abstract：:Although a screening program for gastric cancer, using barium X-ray examination, has been carried out widely in Japan for the past 3 decades, there is insufficient evidence to confirm its effectiveness in terms of reducing mortality. To evaluate the effectiveness of the screening, a population-based case-control study...

journal_title：International journal of cancer

authors： Fukao A,Tsubono Y,Tsuji I,HIsamichi S,Sugahara N,Takano A

更新日期：1995-01-03 00:00:00

abstract：:Human papillomavirus (HPV) is a circular double-stranded DNA virus implicated in at least 90% of cervical and anogenital cancers and has been observed in approximately 20% of squamous cell carcinomas of the head and neck (SCCHN). Transcription of the viral oncogenes E6 and E7 is regulated by expression of the E2 prote...

journal_title：International journal of cancer

authors： Ragin CC,Reshmi SC,Gollin SM

更新日期：2004-07-10 00:00:00

abstract：:In order to update the findings of relative risk associated with cigarette smoking for lung cancer by histologic type in Japan, the data from a population-based cohort study of 91,738 men and women were analyzed. During 1990-1999, 422 lung cancer incident cases were identified. The relative risk for all incident cases...

journal_title：International journal of cancer

authors： Sobue T,Yamamoto S,Hara M,Sasazuki S,Sasaki S,Tsugane S,JPHC Study Group. Japanese Public Health Center.

更新日期：2002-05-10 00:00:00

abstract：:In order to examine the role of cell surface laminin in tumor metastasis we have utilized four well-characterized murine fibrosarcoma cell lines. Two of these lines were highly metastatic when injected into syngeneic mice while the remaining two lines were significantly less metastatic. Using indirect immunofluorescen...

journal_title：International journal of cancer

authors： Malinoff HL,McCoy JP Jr,Varani J,Wicha MS

更新日期：1984-05-15 00:00:00

abstract：:Marked variation in phenotypic expression among BRCA1 and BRCA2 mutation carriers may be partly explained by modifier genes that influence mutation penetrance. Variation in CAG/CAA repeat lengths coding for stretches of glutamines in the C-terminus of the AIB1 protein (amplified in breast cancer 1, a steroid receptor ...

journal_title：International journal of cancer

authors： Hughes DJ,Ginolhac SM,Coupier I,Barjhoux L,Gaborieau V,Bressac-de-Paillerets B,Chompret A,Bignon YJ,Uhrhammer N,Lasset C,Giraud S,Sobol H,Hardouin A,Berthet P,Peyrat JP,Fournier J,Nogues C,Lidereau R,Muller D,Fricke

更新日期：2005-11-01 00:00:00

abstract：:Development of targeted therapeutics is still at its early stage for hepatocellular carcinoma (HCC) due to the incomplete understanding of the confounding regulations at signaling pathway level. In this investigation, gene co-expression-based networking and integrative functional genomic modeling of HCC mRNA profiles ...

journal_title：International journal of cancer

authors： Ramesh V,Ganesan K

更新日期：2016-10-01 00:00:00

abstract：:We performed an integrated array comparative genomic hybridization (aCGH) and expression microarray analysis of 8 normal gastric tissues and 38 primary tumors, including 25 intestinal and 13 diffuse gastric adenocarcinomas to identify genes whose expression is deregulated in association with copy number alteration. Ou...

journal_title：International journal of cancer

authors： Myllykangas S,Junnila S,Kokkola A,Autio R,Scheinin I,Kiviluoto T,Karjalainen-Lindsberg ML,Hollmén J,Knuutila S,Puolakkainen P,Monni O

更新日期：2008-08-15 00:00:00

abstract：:DNA synthesis in heterokaryons of mouse peritoneal macrophages and various proliferating cultured cells was analyzed. Macrophages did not inhibit replication in the nuclei of non-immortalized and spontaneously immortalized cells (rat fibroblasts and macrophages, mouse pre-macrophages, NIH3T3 cells). On the contrary, t...

journal_title：International journal of cancer

authors： Prudovsky IA,Gumeniuk RR,Yegorov YE,Zelenin AV

更新日期：1989-12-15 00:00:00

abstract：:The anatomic site-dependent expression of hematopoietic progenitor cell antigen CD34 is a feature of gastrointestinal stromal tumours (GISTs). The basis for the differential CD34 expression is only incompletely understood. This study aimed at understanding the regulation of CD34 in GISTs and clarification of its site-...

journal_title：International journal of cancer

authors： Bure I,Braun A,Kayser C,Geddert H,Schaefer IM,Cameron S,Ghadimi MB,Ströbel P,Werner M,Hartmann A,Wiemann S,Agaimy A,Haller F,Moskalev EA

更新日期：2017-12-01 00:00:00

abstract：:Carcinoma of the breast is a leading hormone-dependent malignancy, resulting in a high rate of morbidity and mortality. During the complex multi-step process of tumor promotion, this common cancer is initiated as hormone-responsive (HR), non-metastatic cancer, followed by a gradual transition into a highly metastatic ...

journal_title：International journal of cancer

authors： Xing RH,Rabbani SA

更新日期：1999-05-05 00:00:00

abstract：:Cloned lines from 4 different families of B-16 melanoma cells were heated repeatedly in tissue culture at 45 degrees C with step-up time intervals. These lines included the partially heat-resistant lines previously selected at 43 degrees C(HR 43 degrees) from wheat-germ-agglutinin-resistant mutant (WGAR, HR43 degrees)...

journal_title：International journal of cancer

authors： Tao Tw

更新日期：1985-09-15 00:00:00

abstract：:Generation of cytotoxic T lymphocytes (CTL) in vitro and tumor-rejection responses by sensitization of semi-syngeneic mice with tumor-antigen-reconstituted liposomes were investigated. Liposomes were prepared from a crude butanol extract (CBE) of BALBRVD leukemia cells and egg phosphatidylcholine (PC): 1,2-dimyristoyl...

journal_title：International journal of cancer

authors： Shibata R,Noguchi T,Sato T,Akiyoshi K,Sunamoto J,Shiku H,Nakayama E

更新日期：1991-05-30 00:00:00

abstract：:The Swedish Family-Cancer Database was used to analyze second cancers after oral, esophageal, rectal, cervical, genital and skin (squamous cell carcinoma) cancers. A strong and consistent association of second cancers was observed at all these sites, in men and women. As a novel finding, an association of rectal cance...

journal_title：International journal of cancer

authors： Hemminki K,Jiang Y,Dong C

更新日期：2001-07-15 00:00:00

abstract：:The E2F family of transcription factors plays a key role in the control of cell-cycle progression. Some family members may act as oncogenes, others as tumor-suppressor genes. The genetic changes and the expression of E2F-1 and -3 were examined in human gastric and colorectal carcinomas by Southern, Northern and Wester...

journal_title：International journal of cancer

authors： Suzuki T,Yasui W,Yokozaki H,Naka K,Ishikawa T,Tahara E

更新日期：1999-05-17 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) are involved in the pathology of colorectal cancer (CRC). Current efforts to eradicate CRC predominantly focused on targeting the proliferation of rapidly growing cancer epithelial cells. This is largely ineffective with resistance arising in most tumors after exposure to chemotherapy. De...

journal_title：International journal of cancer

authors： Deng X,Ruan H,Zhang X,Xu X,Zhu Y,Peng H,Zhang X,Kong F,Guan M

更新日期：2020-03-15 00:00:00

abstract：:A series of 111 human bladder tumors were screened using oligonucleotide mutant specific probes, restriction enzyme analysis and single-stranded confirmation polymorphism (SSCP) for the presence of H-ras activation events. Thirty-three tumors were found to harbor H-ras mutations where a glycine to valine (G-->T) chang...

journal_title：International journal of cancer

authors： Levesque P,Ramchurren N,Saini K,Joyce A,Libertino J,Summerhayes IC

更新日期：1993-11-11 00:00:00

abstract：:Expression of the macrophage antigen CD163 in breast cancer cells is recently shown to be related to early distant recurrence and shortened survival. In this study, 163 patients with rectal cancer, included in the Swedish rectal cancer trial and followed up for a median of 71 months, were examined for the expression o...

journal_title：International journal of cancer

authors： Shabo I,Olsson H,Sun XF,Svanvik J

更新日期：2009-10-15 00:00:00

abstract：:In 1979, a hypothesis-generating, population-based case-control study was undertaken in Montreal, Canada, to explore the association between occupational exposure to 294 substances, 130 occupations and industries, and various cancers. Interviews were carried out with 3, 630 histologically confirmed cancer cases, of wh...

journal_title：International journal of cancer

authors： Dumas S,Parent ME,Siemiatycki J,Brisson J

更新日期：2000-09-15 00:00:00

abstract：:The cellular tumor suppressor p16 is strongly overexpressed in cervical cancers and precancers. We have previously demonstrated that infiltrating T lymphocytes reactive against p16 can be found in cervical cancer patients. Here, we analyzed whether p16 induces humoral immune responses. Sera of patients with cervical c...

journal_title：International journal of cancer

authors： Reuschenbach M,Waterboer T,Wallin KL,Einenkel J,Dillner J,Hamsikova E,Eschenbach D,Zimmer H,Heilig B,Kopitz J,Pawlita M,Doeberitz Mv,Wentzensen N

更新日期：2008-12-01 00:00:00

abstract：:We show that diacylglycerols, like phorbol myristate acetate (PMA), suppress cell polarity and locomotor activity of Walker carcinosarcoma cells in a dose-dependent fashion in vitro. OAG and diC8 show significant activity at concentrations above 3 x 10(-5) M. The inhibitory effect on locomotion is due to a reduction i...

journal_title：International journal of cancer

authors： Keller HU,Zimmermann A,Niggli V

更新日期：1989-11-15 00:00:00

abstract：:Altered DNA methylation is often seen in malignant cells, potentially contributing to carcinogenesis by suppressing gene expression. We hypothesized that heritable methylation potential might be a risk factor for breast cancer and evaluated possible association with breast cancer for single nucleotide polymorphisms (S...

journal_title：International journal of cancer

authors： Harlid S,Ivarsson MI,Butt S,Hussain S,Grzybowska E,Eyfjörd JE,Lenner P,Försti A,Hemminki K,Manjer J,Dillner J,Carlson J

更新日期：2011-10-01 00:00:00

abstract：:Histologic characteristics of bladder cancer in Boston, USA, Manchester, UK, and Nagoya, Japan, were evaluated. In each of these areas broadly-based series of cases were assembled during a collaborative case-control study. The present analysis was based on 589 cases in Boston, 484 cases in Manchester, and 241 cases in...

journal_title：International journal of cancer

authors： Morrison AS,Proppe KH,Verhoek WG,Aoki K,Leck I,Ohno Y,Obata K

更新日期：1982-12-15 00:00:00

abstract：:Elevated plasma lipoprotein(a) has been associated with an increased risk of cardiovascular disease. We report a significant elevation of total plasma apolipoprotein(a) levels in cancer patients compared with hospitalized control patients and normal healthy blood donors. Of the cancer patients studied, 48% had levels ...

journal_title：International journal of cancer

authors： Wright LC,Sullivan DR,Muller M,Dyne M,Tattersall MH,Mountford CE

更新日期：1989-02-15 00:00:00

abstract：:Our objective was to examine whether parental exposure to atomic bomb radiation has led to increased cancer and/or noncancer mortality rates among the offspring. We studied 41,010 subjects born from May 1946 through December 1984 (i.e., conceived between 1 month and 38 years after the bombings) and surviving for at le...

journal_title：International journal of cancer

authors： Izumi S,Suyama A,Koyama K

更新日期：2003-11-01 00:00:00

abstract：:Interleukin-12 (IL-12) has potent antitumor activities via natural killer cells and cytotoxic T lymphocytes. However, the molecular mechanisms whereby IL-12 induces tumoricidal activities are poorly understood. Here, we report the genome-wide analysis of gene expression in a primary murine mammary carcinoma model that...

journal_title：International journal of cancer

authors： Shi X,Liu J,Xiang Z,Mitsuhashi M,Wu RS,Ma X

更新日期：2004-07-01 00:00:00

abstract：:Three polycyclic hydrocarbons, benz(a)anthracene, 3-methylcholanthrene and 7,12-dimethylbenz(a)anthracene, have been studied in a cell-mediated mutagenesis system using BHK 21 cells to metabolize the hydrocarbons and V-79 cells as targets for detecting induced cytotoxicity and mutation. In large-scale experiments, the...

journal_title：International journal of cancer

authors： Wigley CB,Newbold RF,Amos J,Brookes P

更新日期：1979-05-15 00:00:00

abstract：:Childhood cancers (age at diagnosis: 0-14 years) comprise a variety of malignancies, with incidence varying worldwide by age, sex, ethnicity and geography, that provide insights into cancer etiology. A total of 1,334 childhood cancers registered in population-based cancer registry, Chennai, India, during 1990-2001 and...

journal_title：International journal of cancer

authors： Swaminathan R,Rama R,Shanta V

更新日期：2008-06-01 00:00:00

abstract：:The association between Lichen planus (LP) and cancer has been under debate for decades. We studied the connection via population-based Finnish register data. All women with the diagnosis of LP (n = 13,100) were identified from the Finnish Hospital Discharge Registry from 1969-2012. These patients were linked with sub...

journal_title：International journal of cancer

authors： Halonen P,Jakobsson M,Heikinheimo O,Riska A,Gissler M,Pukkala E

更新日期：2018-01-01 00:00:00