Macular Telangiectasia Type 2 Without Clinically Detectable Vasculopathy.

abstract：IMPORTANCE:Anterior chamber seeding following intraophthalmic artery chemotherapy is rarely reported. OBJECTIVES:To describe clinicopathologic observations in eyes in which intraophthalmic artery chemotherapy for retinoblastoma failed and to report anterior chamber involvement. OBSERVATIONS:A retrospective case serie...

journal_title：JAMA ophthalmology

authors： Pavlidou E,Burris C,Thaung C,Scheimberg I,Kingston J,Hungerford JL,Reddy MA,Sagoo MS

更新日期：2015-12-01 00:00:00

abstract：Importance:Identifying the course of glaucomatous visual field (VF) loss that progresses from normal to perimetric blindness is important for treatment and prognostication. Objective:To model the process of glaucomatous VF decay over the entire perimetric range from normal to perimetric blindness. Design, Setting, an...

journal_title：JAMA ophthalmology

authors： Otarola F,Chen A,Morales E,Yu F,Afifi A,Caprioli J

更新日期：2016-05-01 00:00:00

abstract：IMPORTANCE:The clinical features of the follicular subtype of ocular adnexal lymphoma (OAL) have not been previously evaluated in a large cohort. OBJECTIVE:To characterize the clinical features of follicular OAL. DESIGN, SETTING, AND PARTICIPANTS:We performed a retrospective multicenter study that involved 6 eye canc...

journal_title：JAMA ophthalmology

authors： Rasmussen PK,Coupland SE,Finger PT,Graue GF,Grossniklaus HE,Honavar SG,McKelvie P,Mulay K,Prause JU,Ralfkiaer E,Sjö LD,Heegaard S

更新日期：2014-07-01 00:00:00

abstract：IMPORTANCE:Myopia (nearsightedness) has its onset in childhood and affects about one-third of adults in the United States. Along with its high prevalence, myopia is expensive to correct and is associated with ocular diseases that include glaucoma and retinal detachment. OBJECTIVE:To determine the best set of predictor...

journal_title：JAMA ophthalmology

authors： Zadnik K,Sinnott LT,Cotter SA,Jones-Jordan LA,Kleinstein RN,Manny RE,Twelker JD,Mutti DO,Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study Group.

更新日期：2015-06-01 00:00:00

abstract：Importance:Congenital Zika syndrome (CZS) is known to be associated with severe malformations in newborns. Although microcephaly is the hallmark of this disease, the ocular findings are important given the severe visual impairment that has been observed in these patients. Regardless of the increased number of CZS cases...

journal_title：JAMA ophthalmology

authors： Fernandez MP,Parra Saad E,Ospina Martinez M,Corchuelo S,Mercado Reyes M,Herrera MJ,Parra Saavedra M,Rico A,Fernandez AM,Lee RK,Ventura CV,Berrocal AM,Dubovy SR

更新日期：2017-11-01 00:00:00

abstract：IMPORTANCE:We describe a sign that can be used as a rapid and noninvasive adjunct to aid in the diagnosis of foveal hypoplasia. OBJECTIVE:To describe a concentric macular rings sign found on infrared reflectance (IRR) images in patients with foveal hypoplasia. DESIGN, SETTING, AND PATIENTS:We studied 13 patients with...

journal_title：JAMA ophthalmology

authors： Cornish KS,Reddy AR,McBain VA

更新日期：2014-09-01 00:00:00

abstract：Importance:Visual impairment and visual disorders often co-occur with other chronic conditions. Understanding patterns of multimorbidity is important for reducing health care use and improving health outcomes. Objective:To identify chronic condition patterns and their association with visual impairment and health care...

journal_title：JAMA ophthalmology

authors： Zheng DD,Christ SL,Lam BL,Feaster DJ,McCollister K,Lee DJ

更新日期：2020-04-01 00:00:00

abstract：IMPORTANCE:To facilitate comparative clinical outcome research in low vision rehabilitation, we must use patient-centered measurements that reflect clinically meaningful changes in visual ability. OBJECTIVE:To quantify the effects of currently provided low vision rehabilitation (LVR) on patients who present for outpat...

journal_title：JAMA ophthalmology

authors： Goldstein JE,Jackson ML,Fox SM,Deremeik JT,Massof RW,Low Vision Research Network Study Group.

更新日期：2015-07-01 00:00:00

abstract：Importance:After long-duration spaceflight, morphological changes in the optic nerve head (ONH) and surrounding tissues have been reported. Objective:To develop methods to quantify ONH and surrounding tissue changes using preflight and postflight optical coherence tomographic scans of the ONH region. Design, Setting,...

journal_title：JAMA ophthalmology

authors： Patel N,Pass A,Mason S,Gibson CR,Otto C

更新日期：2018-02-01 00:00:00

abstract：Importance:Immune checkpoint inhibitors, including antiprogrammed cell death protein-1 (anti-PD-1) and antiprogrammed cell death ligand-1 (anti-PD-L1) monoclonal antibodies, have recently been introduced as a promising new immunotherapy for solid cancers. The adverse effects typically include inflammation of the skin, ...

journal_title：JAMA ophthalmology

authors： Thomas M,Armenti ST,Ayres MB,Demirci H

更新日期：2018-05-01 00:00:00

abstract：IMPORTANCE:Anti-vascular endothelial growth factor (VEGF) medicines have revolutionized diabetic macular edema (DME) treatment. A recent randomized clinical trial comparing anti-VEGF agents for patients with decreased vision from DME found that at 1 year aflibercept (2.0 mg) achieved better visual outcomes than repacka...

journal_title：JAMA ophthalmology

authors： Ross EL,Hutton DW,Stein JD,Bressler NM,Jampol LM,Glassman AR,Diabetic Retinopathy Clinical Research Network.

更新日期：2016-08-01 00:00:00

abstract：Importance:Uveitis has been associated with psoriatic arthritis, but to our knowledge, the relationship between uveitis and psoriasis is unsettled among researchers. Objective:To evaluate the risk of incident uveitis among people with psoriasis. Design, Setting, and Participants:This nationwide, retrospective cohort ...

journal_title：JAMA ophthalmology

authors： Chi CC,Tung TH,Wang J,Lin YS,Chen YF,Hsu TK,Wang SH

更新日期：2017-05-01 00:00:00

abstract：IMPORTANCE:The effect of glaucoma on nonglaucomatous medical conditions and resultant secondary health care costs is not well understood. OBJECTIVE:To assess self-reported medical conditions, the use of medical services, and total health care costs among Medicare beneficiaries with glaucoma. DESIGN, SETTING, AND PART...

journal_title：JAMA ophthalmology

authors： Prager AJ,Liebmann JM,Cioffi GA,Blumberg DM

更新日期：2016-04-01 00:00:00

abstract：Importance:Although low-income populations have more eye problems, whether they face greater difficulty obtaining eye care appointments is unknown. Objective:To compare rates of obtaining eye care appointments and appointment wait times for those with Medicaid vs those with private insurance. Design, Setting, and Par...

journal_title：JAMA ophthalmology

authors： Lee YH,Chen AX,Varadaraj V,Hong GH,Chen Y,Friedman DS,Stein JD,Kourgialis N,Ehrlich JR

更新日期：2018-06-01 00:00:00

abstract：IMPORTANCE:This study confirmed the long-term outcomes of the ZB5M phakic intraocular lens (PIOL). OBJECTIVE:To evaluate the potential long-term risk associated with ZB5M PIOL implantation. DESIGN, SETTING, AND PARTICIPANTS:A retrospective, nonrandomized, consecutive cohort study of a total of 208 eyes implanted with...

journal_title：JAMA ophthalmology

authors： Alio JL,Abbouda A,Peña-Garcia P,Huseynli S

更新日期：2013-12-01 00:00:00

abstract：IMPORTANCE:Although trabeculotomy is a glaucoma surgical procedure for modest intraocular pressure (IOP) reduction, some eyes exhibit very low IOP during the early postoperative period. To our knowledge, the reason and its effect have not been investigated. OBJECTIVES:To investigate ciliochoroidal detachment (CCD) imm...

journal_title：JAMA ophthalmology

authors： Akagi T,Nakano E,Nakanishi H,Uji A,Yoshimura N

更新日期：2016-03-01 00:00:00

abstract：IMPORTANCE:We present a method to reintroduce ophthalmic training into the medical school curriculum. OBJECTIVES:To evaluate knowledge and skills acquired when participating in a service project, the Community Vision Project, and to develop a quantitative method for testing skills with the direct ophthalmoscope in pat...

journal_title：JAMA ophthalmology

authors： Byrd JM,Longmire MR,Syme NP,Murray-Krezan C,Rose L

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:Visualization and interpretation of the optic nerve and retina are essential parts of most physical examinations. OBJECTIVE:To design and validate a smartphone-based retinal adapter enabling image capture and remote grading of the retina. DESIGN, SETTING, AND PARTICIPANTS:This validation study compared the...

journal_title：JAMA ophthalmology

authors： Bastawrous A,Giardini ME,Bolster NM,Peto T,Shah N,Livingstone IA,Weiss HA,Hu S,Rono H,Kuper H,Burton M

更新日期：2016-02-01 00:00:00

abstract：Importance:Both primary and secondary forms of childhood glaucoma have many distinct causative mechanisms, and in many cases a cause is not immediately clear. The broad phenotypic spectrum of secondary glaucoma, particularly in individuals with variants in FOXC1 or PITX2 genes associated with Axenfeld-Rieger syndrome, ...

journal_title：JAMA ophthalmology

authors： Siggs OM,Souzeau E,Pasutto F,Dubowsky A,Smith JEH,Taranath D,Pater J,Rait JL,Narita A,Mauri L,Del Longo A,Reis A,Chappell A,Kearns LS,Staffieri SE,Elder JE,Ruddle JB,Hewitt AW,Burdon KP,Mackey DA,Craig JE

更新日期：2019-04-01 00:00:00

abstract：Importance:Because studies have suggested that atropine might slow the progression of myopia in children, randomized clinical trials are warranted to understand this potential causal relationship. Objective:To evaluate the efficacy and safety of atropine, 0.01%, eyedrops on slowing myopia progression and axial elongat...

journal_title：JAMA ophthalmology

authors： Wei S,Li SM,An W,Du J,Liang X,Sun Y,Zhang D,Tian J,Wang N

更新日期：2020-10-01 00:00:00

abstract：IMPORTANCE:Increased lipofuscin accumulation is assumed to be an important factor in the pathogenesis of age-related macular degeneration (AMD), although direct evidence for this hypothesis is missing. OBJECTIVE:To quantitatively investigate lipofuscin-associated fundus autofluorescence (AF) in patients with early and...

journal_title：JAMA ophthalmology

authors： Gliem M,Müller PL,Finger RP,McGuinness MB,Holz FG,Charbel Issa P

更新日期：2016-07-01 00:00:00

abstract：IMPORTANCE:Descemet stripping automated endothelial keratoplasty (DSAEK) for isolated endothelial dysfunction has become the preferred surgical option for many corneal surgeons. However, there are limited large-scale reports on DSAEK survival and clinical variables affecting the risk of rejection and failure after fail...

journal_title：JAMA ophthalmology

authors： Mitry D,Bhogal M,Patel AK,Lee BS,Chai SM,Price MO,Price FW Jr,Jun AS,Aldave AJ,Mehta JS,Busin M,Allan BD

更新日期：2014-06-01 00:00:00

abstract：Importance:Certain features of the lamina cribrosa may be associated with increased risk of glaucoma progression. Objectives:To compare the rates of retinal nerve fiber layer (RNFL) thinning in patients with open-angle glaucoma with or without lamina cribrosa (LC) defects and to evaluate factors associated with the ra...

journal_title：JAMA ophthalmology

authors： Moghimi S,Zangwill LM,Manalastas PIC,Suh MH,Penteado RC,Hou H,Hasenstab K,Ghahari E,Bowd C,Weinreb RN

更新日期：2019-04-01 00:00:00

abstract：:IMPORTANCE Advanced glycation end products have been implicated in the pathogenesis of age-related macular degeneration (AMD). OBJECTIVE To investigate the relationship between serum carboxymethyllysine (CML), a major circulating advanced glycation end product, and AMD in older adults. DESIGN, SETTING, AND PARTICIPANT...

journal_title：JAMA ophthalmology

authors： Semba RD,Cotch MF,Gudnason V,Eiríksdottir G,Harris TB,Sun K,Klein R,Jonasson F,Ferrucci L,Schaumberg DA

更新日期：2014-04-01 00:00:00

abstract：Importance:Examining costs and consequences of different low-vision (LV) programs provides important information about resources needed to expand treatment options efficiently. Objective:To examine the costs and consequences of LV rehabilitation or basic LV services. Design, Setting, and Participants:The US Departmen...

journal_title：JAMA ophthalmology

authors： Stroupe KT,Stelmack JA,Tang XC,Wei Y,Sayers S,Reda DJ,Kwon E,Massof RW,LOVIT II Study Group.

更新日期：2018-05-01 00:00:00

abstract：Importance:The Diabetic Retinopathy Clinical Research Network Protocol S randomized clinical trial results suggest that ranibizumab is a reasonable treatment alternative to panretinal photocoagulation (PRP) when managing proliferative diabetic retinopathy (PDR), with or without concomitant baseline diabetic macular ede...

journal_title：JAMA ophthalmology

authors： Hutton DW,Stein JD,Bressler NM,Jampol LM,Browning D,Glassman AR,Diabetic Retinopathy Clinical Research Network.

更新日期：2017-06-01 00:00:00

abstract：IMPORTANCE:The optic disc pit (ODP) has been considered a region of localized susceptibility to the damage of glaucoma. OBJECTIVE:To determine whether the rate of retinal nerve fiber layer (RNFL) thinning differs according to the presence and structural characteristics of an ODP in primary open-angle glaucoma. DESIGN...

journal_title：JAMA ophthalmology

authors： Lee SH,Lee EJ,Kim TW

更新日期：2015-10-01 00:00:00

abstract：Importance:Vitreoretinal lymphoma is a diagnostic challenge and the pathophysiology is still unclear. Objective:To describe an imaging finding seen on optical coherence tomography (OCT) of patients with vitreoretinal lymphoma. Design, Setting, and Participants:This case series study was a retrospective medical record...

journal_title：JAMA ophthalmology

authors： Deák GG,Goldstein DA,Zhou M,Fawzi AA,Jampol LM

更新日期：2019-02-01 00:00:00

abstract：:Within 20 years of its discovery 100 years ago, vitamin A was recognized as critical to normal eyes, growth, and survival. Clinical interest subsequently contracted to its importance in preventing xerophthalmia, until this ophthalmologist stumbled, quite accidently, on its role in fighting life-threatening infections....

journal_title：JAMA ophthalmology

authors： Sommer A

更新日期：2014-01-01 00:00:00

abstract：Importance:Coronavirus disease 2019 (COVID-19) has been recognized as a pandemic by the World Health Organization. Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can also infect tissues besides the respiratory system, such as the ocular tissues, remains unclear. Objective:To determine whether SAR...

journal_title：JAMA ophthalmology

authors： Yan Y,Diao B,Liu Y,Zhang W,Wang G,Chen X

更新日期：2020-10-08 00:00:00