Follow-up study of more than 15 years of an angle-supported phakic intraocular lens model (ZB5M) for high myopia: outcomes and complications.

abstract：Importance:There are limited published data on the phenotype of retinitis pigmentosa (RP) related to CNGB1 variants. These data are needed both for prognostic counseling of patients and for understanding potential treatment windows. Objective:To describe the detailed clinical and molecular genetic findings in a series...

journal_title：JAMA ophthalmology

authors： Hull S,Attanasio M,Arno G,Carss K,Robson AG,Thompson DA,Plagnol V,Michaelides M,Holder GE,Henderson RH,Raymond FL,Moore AT,Webster AR

更新日期：2017-02-01 00:00:00

abstract：Importance:The Diabetic Retinopathy Clinical Research Network Protocol S randomized clinical trial results suggest that ranibizumab is a reasonable treatment alternative to panretinal photocoagulation (PRP) when managing proliferative diabetic retinopathy (PDR), with or without concomitant baseline diabetic macular ede...

journal_title：JAMA ophthalmology

authors： Hutton DW,Stein JD,Bressler NM,Jampol LM,Browning D,Glassman AR,Diabetic Retinopathy Clinical Research Network.

更新日期：2017-06-01 00:00:00

abstract：Importance:Mobility limitations arising from vision impairment (VI) can result in loss of independence and reduced quality of life. However, few data are available on the association between VI and mobility limitations at a population-based level, particularly in Asian populations. Objective:To assess the association ...

journal_title：JAMA ophthalmology

authors： Fenwick EK,Ong PG,Man RE,Cheng CY,Sabanayagam C,Wong TY,Lamoureux EL

更新日期：2016-10-01 00:00:00

abstract：Importance:Knowledge of the incidence and progression of diabetic retinopathy (DR) after gastric bypass surgery (GBP) in patients with obesity and diabetes could guide the management of these patients. Objective:To investigate the incidence of diabetic ocular complications in patients with type 2 diabetes after GBP co...

journal_title：JAMA ophthalmology

authors： Åkerblom H,Franzén S,Zhou C,Morén Å,Ottosson J,Sundbom M,Eliasson B,Svensson AM,Granstam E

更新日期：2021-01-14 00:00:00

abstract：Importance:Glaucoma-related adverse events constitute serious complications of cataract removal in infancy, yet long-term data on incidence and visual outcome remain lacking. Objective:To identify and characterize incident cases of glaucoma and glaucoma-related adverse events (glaucoma + glaucoma suspect) among childr...

journal_title：JAMA ophthalmology

authors： Freedman SF,Beck AD,Nizam A,Vanderveen DK,Plager DA,Morrison DG,Drews-Botsch CD,Lambert SR,Infant Aphakia Treatment Study Group.

更新日期：2020-12-17 00:00:00

abstract：IMPORTANCE:We describe a sign that can be used as a rapid and noninvasive adjunct to aid in the diagnosis of foveal hypoplasia. OBJECTIVE:To describe a concentric macular rings sign found on infrared reflectance (IRR) images in patients with foveal hypoplasia. DESIGN, SETTING, AND PATIENTS:We studied 13 patients with...

journal_title：JAMA ophthalmology

authors： Cornish KS,Reddy AR,McBain VA

更新日期：2014-09-01 00:00:00

abstract：IMPORTANCE:The publication of the US Physician Payments Sunshine Act provides insight into the financial relationship between physicians and the pharmaceutical industry. This added transparency creates new opportunities of using objective data to better understand prior research that implicates pharmaceutical promotion...

journal_title：JAMA ophthalmology

authors： Taylor SC,Huecker JB,Gordon MO,Vollman DE,Apte RS

更新日期：2016-08-01 00:00:00

abstract：IMPORTANCE:Anterior chamber seeding following intraophthalmic artery chemotherapy is rarely reported. OBJECTIVES:To describe clinicopathologic observations in eyes in which intraophthalmic artery chemotherapy for retinoblastoma failed and to report anterior chamber involvement. OBSERVATIONS:A retrospective case serie...

journal_title：JAMA ophthalmology

authors： Pavlidou E,Burris C,Thaung C,Scheimberg I,Kingston J,Hungerford JL,Reddy MA,Sagoo MS

更新日期：2015-12-01 00:00:00

abstract：Importance:Unverifiable publications in applications for ophthalmology residencies could be a serious concern if they represent publication dishonesty. Objective:To determine the rate of unverifiable publications among applicants offered an interview. Design:Retrospective review of 322 ophthalmology residency applica...

journal_title：JAMA ophthalmology

authors： Tamez HM,Tauscher R,Brown EN,Wayman L,Mawn LA

更新日期：2018-06-01 00:00:00

abstract：IMPORTANCE:Patching has been a mainstay in treating unilateral congenital cataract. However, its efficacy has not been rigorously assessed. OBJECTIVE:To examine the association between patching and visual acuity in a cohort of children treated for unilateral congenital cataract. DESIGN, SETTING, AND PARTICIPANTS:This...

journal_title：JAMA ophthalmology

authors： Drews-Botsch C,Celano M,Cotsonis G,Hartmann EE,Lambert SR,Infant Aphakia Treatment Study Group.

更新日期：2016-08-01 00:00:00

abstract：Objective:To compare oral voriconazole with placebo in addition to topical antifungals in the treatment of filamentous fungal keratitis. Design, Setting, and Participants:The Mycotic Ulcer Treatment Trial II (MUTT II), a multicenter, double-masked, placebo-controlled, randomized clinical trial, was conducted in India ...

journal_title：JAMA ophthalmology

authors： Prajna NV,Krishnan T,Rajaraman R,Patel S,Srinivasan M,Das M,Ray KJ,O'Brien KS,Oldenburg CE,McLeod SD,Zegans ME,Porco TC,Acharya NR,Lietman TM,Rose-Nussbaumer J,Mycotic Ulcer Treatment Trial II Group.

更新日期：2016-12-01 00:00:00

abstract：IMPORTANCE:A large number of genes can cause inherited retinal degenerations when mutated. It is important to identify the cause of disease for a better disease prognosis and a possible gene-specific therapeutic intervention. OBJECTIVE:To identify the cause of disease in families with nonsyndromic retinitis pigmentosa...

journal_title：JAMA ophthalmology

authors： Shevach E,Ali M,Mizrahi-Meissonnier L,McKibbin M,El-Asrag M,Watson CM,Inglehearn CF,Ben-Yosef T,Blumenfeld A,Jalas C,Banin E,Sharon D

更新日期：2015-03-01 00:00:00

abstract：Importance:Visual acuity (VA) outcomes differ considerably among patients with neovascular age-related macular degeneration (nAMD) treated with anti-vascular endothelial growth factor (VEGF) drugs. Identification of pharmacogenetic associations may help clinicians understand the mechanisms underlying this variability a...

journal_title：JAMA ophthalmology

authors： Lorés-Motta L,Riaz M,Grunin M,Corominas J,van Asten F,Pauper M,Leenders M,Richardson AJ,Muether P,Cree AJ,Griffiths HL,Pham C,Belanger MC,Meester-Smoor MA,Ali M,Heid IM,Fritsche LG,Chakravarthy U,Gale R,McKibbin M,

更新日期：2018-08-01 00:00:00

abstract：Importance:To our knowledge, a set of well-defined diagnostic criteria is not yet developed for the diagnosis of Vogt-Koyanagi-Harada (VKH) disease. Objective:To develop and evaluate a set of diagnostic criteria for VKH disease using data from Chinese patients. Design, Setting, and Participants:This case-control stud...

journal_title：JAMA ophthalmology

authors： Yang P,Zhong Y,Du L,Chi W,Chen L,Zhang R,Zhang M,Wang H,Lu H,Yang L,Zhuang W,Yang Y,Xing L,Feng L,Jiang Z,Zhang X,Wang Y,Zhong H,Jiang L,Zhao C,Li F,Cao S,Liu X,Chen X,Shi Y,Zhao W,Kijlstra A

更新日期：2018-09-01 00:00:00

abstract：IMPORTANCE:The presence of choroidal hyperreflective foci in Stargardt disease is, to our knowledge, a potentially new finding. Evaluation of these foci may aid in better understanding of the disease process. OBJECTIVES:To report the presence of choroidal hyperreflective foci in spectral-domain optical coherence tomog...

journal_title：JAMA ophthalmology

authors： Piri N,Nesmith BL,Schaal S

更新日期：2015-04-01 00:00:00

abstract：IMPORTANCE:Visualization and interpretation of the optic nerve and retina are essential parts of most physical examinations. OBJECTIVE:To design and validate a smartphone-based retinal adapter enabling image capture and remote grading of the retina. DESIGN, SETTING, AND PARTICIPANTS:This validation study compared the...

journal_title：JAMA ophthalmology

authors： Bastawrous A,Giardini ME,Bolster NM,Peto T,Shah N,Livingstone IA,Weiss HA,Hu S,Rono H,Kuper H,Burton M

更新日期：2016-02-01 00:00:00

abstract：IMPORTANCE:We define a Reading Accessibility Index for evaluating reading in individuals with normal and low vision. OBJECTIVE:To compare the Reading Accessibility Index with data from the Impact of Cataracts on Mobility (ICOM) study. DESIGN, SETTING, AND PARTICIPANTS:This investigation was a secondary data analysis ...

journal_title：JAMA ophthalmology

authors： Calabrèse A,Owsley C,McGwin G,Legge GE

更新日期：2016-04-01 00:00:00

abstract：IMPORTANCE:Tuberculosis is an endemic infectious disease in developing countries. Patients receiving treatment for systemic tuberculosis may develop paradoxical growth of tuberculomas in the brain, which can lead to vision loss. OBSERVATIONS:We describe 3 patients who had paradoxical development of tuberculomas in the...

journal_title：JAMA ophthalmology

authors： Joseph M,Mendonca TM,Vasu U,Nithyanandam S,Mathew T

更新日期：2013-11-01 00:00:00

abstract：IMPORTANCE:We conducted a series of phase 1 clinical trials to elucidate the efficacy and safety of the selective Rho kinase inhibitor K-115 as a candidate drug for the treatment of glaucoma. We report the intraocular pressure (IOP)-lowering effects and safety of K-115 based on our results. OBJECTIVE:To study the IOP-...

journal_title：JAMA ophthalmology

authors： Tanihara H,Inoue T,Yamamoto T,Kuwayama Y,Abe H,Araie M,K-115 Clinical Study Group.

更新日期：2013-10-01 00:00:00

abstract：IMPORTANCE:The optic disc pit (ODP) has been considered a region of localized susceptibility to the damage of glaucoma. OBJECTIVE:To determine whether the rate of retinal nerve fiber layer (RNFL) thinning differs according to the presence and structural characteristics of an ODP in primary open-angle glaucoma. DESIGN...

journal_title：JAMA ophthalmology

authors： Lee SH,Lee EJ,Kim TW

更新日期：2015-10-01 00:00:00

abstract：Importance:A precise phenotypic characterization of retinal dystrophies is needed for disease modeling as a basis for future therapeutic interventions. Objective:To compare genotype, phenotype, and structural changes in patients with rod-cone dystrophy (RCD) associated with mutations in PDE6A or PDE6B. Design, Settin...

journal_title：JAMA ophthalmology

authors： Khateb S,Nassisi M,Bujakowska KM,Méjécase C,Condroyer C,Antonio A,Foussard M,Démontant V,Mohand-Saïd S,Sahel JA,Zeitz C,Audo I

更新日期：2019-06-01 00:00:00

abstract：IMPORTANCE:Binocular summation (BiS) is defined as the superiority of visual function for binocular over monocular viewing. Binocular summation decreases with age and large interocular differences in visual acuity. To our knowledge, BiS has not heretofore been well studied as a functional measure of binocularity in str...

journal_title：JAMA ophthalmology

authors： Pineles SL,Velez FG,Isenberg SJ,Fenoglio Z,Birch E,Nusinowitz S,Demer JL

更新日期：2013-11-01 00:00:00

abstract：Importance:After long-duration spaceflight, morphological changes in the optic nerve head (ONH) and surrounding tissues have been reported. Objective:To develop methods to quantify ONH and surrounding tissue changes using preflight and postflight optical coherence tomographic scans of the ONH region. Design, Setting,...

journal_title：JAMA ophthalmology

authors： Patel N,Pass A,Mason S,Gibson CR,Otto C

更新日期：2018-02-01 00:00:00

abstract：IMPORTANCE:Further research is crucial to better understand the reason for falls in individuals with visual impairment (VI) and to develop appropriate fall prevention strategies. OBJECTIVE:To compare balance measures in individuals with normal vision, VI, and uncorrected refractive error (URE). DESIGN AND SETTING:Cro...

journal_title：JAMA ophthalmology

authors： Willis JR,Vitale SE,Agrawal Y,Ramulu PY

更新日期：2013-08-01 00:00:00

abstract：Importance:Many ophthalmology appointments have been converted to telemedicine assessments. The use of a printed vision chart for ophthalmology telemedicine appointments that can be used by people who are excluded from digital testing has yet to be validated. Objectives:To evaluate the repeatability of visual acuity m...

journal_title：JAMA ophthalmology

authors： Crossland MD,Dekker TM,Hancox J,Lisi M,Wemyss TA,Thomas PBM

更新日期：2021-01-07 00:00:00

abstract：Importance:It is well established from different population-based studies that visual impairment is associated with increased mortality rate. However, to our knowledge, the association of visual impairment with increased mortality rate has not been reported among indigenous Australian individuals. Objective:To assess ...

journal_title：JAMA ophthalmology

authors： Ng SK,Kahawita S,Andrew NH,Henderson T,Craig JE,Landers J

更新日期：2018-05-01 00:00:00

abstract：Importance:The comparative clinical effectiveness of ranibizumab, aflibercept, and bevacizumab for the management of macular edema due to central retinal vein occlusion (CRVO) is unclear. Objective:To determine whether intravitreal aflibercept or bevacizumab compared with ranibizumab results in a noninferior mean chan...

journal_title：JAMA ophthalmology

authors： Hykin P,Prevost AT,Vasconcelos JC,Murphy C,Kelly J,Ramu J,Hounsome B,Yang Y,Harding SP,Lotery A,Chakravarthy U,Sivaprasad S,LEAVO Study Group.

更新日期：2019-08-29 00:00:00

abstract：IMPORTANCE:The effect of glaucoma on nonglaucomatous medical conditions and resultant secondary health care costs is not well understood. OBJECTIVE:To assess self-reported medical conditions, the use of medical services, and total health care costs among Medicare beneficiaries with glaucoma. DESIGN, SETTING, AND PART...

journal_title：JAMA ophthalmology

authors： Prager AJ,Liebmann JM,Cioffi GA,Blumberg DM

更新日期：2016-04-01 00:00:00

abstract：Importance:Certain features of the lamina cribrosa may be associated with increased risk of glaucoma progression. Objectives:To compare the rates of retinal nerve fiber layer (RNFL) thinning in patients with open-angle glaucoma with or without lamina cribrosa (LC) defects and to evaluate factors associated with the ra...

journal_title：JAMA ophthalmology

authors： Moghimi S,Zangwill LM,Manalastas PIC,Suh MH,Penteado RC,Hou H,Hasenstab K,Ghahari E,Bowd C,Weinreb RN

更新日期：2019-04-01 00:00:00

abstract：Importance:Most premature infants will not develop retinopathy of prematurity (ROP) of clinical relevance, yet screening evaluations often continue beyond hospital discharge, even for those infants without ROP. Objectives:To identify the characteristics of infants at low risk for ROP, for whom further postdischarge sc...

journal_title：JAMA ophthalmology

authors： Wade KC,Ying GS,Baumritter A,Gong A,Kemper AR,Quinn GE,e-ROP Cooperative Group.

更新日期：2019-02-01 00:00:00