Paradoxical growth of presumed optochiasmatic tuberculomas following medical therapy.

abstract：IMPORTANCE:Accurate diagnosis of choroidal melanoma is challenging and has important implications for both physicians and patients. We assessed the utility of quantification of fundus autofluorescence in the evaluation and follow-up of choroidal nevomelanocytic tumors. OBJECTIVE:To assess the utility of autofluorescen...

journal_title：JAMA ophthalmology

authors： Albertus DL,Schachar IH,Zahid S,Elner VM,Demirci H,Jayasundera T

更新日期：2013-08-01 00:00:00

abstract：IMPORTANCE:The CX3CR1 gene is implicated as a candidate gene for age-related macular degeneration (AMD) through several lines of evidence. There is uncertainty, however, as to whether common genetic variants in CX3CR1 alter risk of AMD, since prior studies have been inconsistent and mostly limited to evaluation of 2 no...

journal_title：JAMA ophthalmology

authors： Schaumberg DA,Rose L,DeAngelis MM,Semba RD,Hageman GS,Chasman DI

更新日期：2014-01-01 00:00:00

abstract：Importance:Unverifiable publications in applications for ophthalmology residencies could be a serious concern if they represent publication dishonesty. Objective:To determine the rate of unverifiable publications among applicants offered an interview. Design:Retrospective review of 322 ophthalmology residency applica...

journal_title：JAMA ophthalmology

authors： Tamez HM,Tauscher R,Brown EN,Wayman L,Mawn LA

更新日期：2018-06-01 00:00:00

abstract：IMPORTANCE:This study confirmed the long-term outcomes of the ZB5M phakic intraocular lens (PIOL). OBJECTIVE:To evaluate the potential long-term risk associated with ZB5M PIOL implantation. DESIGN, SETTING, AND PARTICIPANTS:A retrospective, nonrandomized, consecutive cohort study of a total of 208 eyes implanted with...

journal_title：JAMA ophthalmology

authors： Alio JL,Abbouda A,Peña-Garcia P,Huseynli S

更新日期：2013-12-01 00:00:00

abstract：Importance:Because studies have suggested that atropine might slow the progression of myopia in children, randomized clinical trials are warranted to understand this potential causal relationship. Objective:To evaluate the efficacy and safety of atropine, 0.01%, eyedrops on slowing myopia progression and axial elongat...

journal_title：JAMA ophthalmology

authors： Wei S,Li SM,An W,Du J,Liang X,Sun Y,Zhang D,Tian J,Wang N

更新日期：2020-10-01 00:00:00

abstract：IMPORTANCE:Children with a history of amblyopia, even if resolved, exhibit impaired visual-auditory integration and perceive speech differently. OBJECTIVE:To determine whether a history of amblyopia is associated with abnormal visual-auditory speech integration. DESIGN, SETTING, AND PARTICIPANTS:Retrospective observa...

journal_title：JAMA ophthalmology

authors： Burgmeier R,Desai RU,Farner KC,Tiano B,Lacey R,Volpe NJ,Mets MB

更新日期：2015-01-01 00:00:00

abstract：Importance:Congenital Zika syndrome (CZS) is known to be associated with severe malformations in newborns. Although microcephaly is the hallmark of this disease, the ocular findings are important given the severe visual impairment that has been observed in these patients. Regardless of the increased number of CZS cases...

journal_title：JAMA ophthalmology

authors： Fernandez MP,Parra Saad E,Ospina Martinez M,Corchuelo S,Mercado Reyes M,Herrera MJ,Parra Saavedra M,Rico A,Fernandez AM,Lee RK,Ventura CV,Berrocal AM,Dubovy SR

更新日期：2017-11-01 00:00:00

abstract：IMPORTANCE:African American individuals are at high risk of diabetes mellitus and diabetic retinopathy but have suboptimal rates of dilated fundus examinations (DFEs). Early intervention is crucial for the prevention of diabetic retinopathy in this high-risk population. OBJECTIVE:To test the efficacy of behavioral act...

journal_title：JAMA ophthalmology

authors： Weiss DM,Casten RJ,Leiby BE,Hark LA,Murchison AP,Johnson D,Stratford S,Henderer J,Rovner BW,Haller JA

更新日期：2015-09-01 00:00:00

abstract：IMPORTANCE:The presence of choroidal hyperreflective foci in Stargardt disease is, to our knowledge, a potentially new finding. Evaluation of these foci may aid in better understanding of the disease process. OBJECTIVES:To report the presence of choroidal hyperreflective foci in spectral-domain optical coherence tomog...

journal_title：JAMA ophthalmology

authors： Piri N,Nesmith BL,Schaal S

更新日期：2015-04-01 00:00:00

abstract：IMPORTANCE:Eye and vision disease burden should help guide ophthalmologic research prioritization. The Global Burden of Disease (GBD) Study 2010 compiled data from 1990 to 2010 on 291 diseases and injuries, 1160 disease and injury sequelae, and 67 risk factors in 187 countries. The Cochrane Database of Systematic Revie...

journal_title：JAMA ophthalmology

authors： Boyers LN,Karimkhani C,Hilton J,Richheimer W,Dellavalle RP

更新日期：2015-01-01 00:00:00

abstract：Importance:Congenital stationary night blindness (CSNB) implies a stable condition, with the major symptom being nyctalopia present at birth. Pediatric clinical presentation and the course of different genetic subtypes of CSNB have not, to our knowledge, been well described in the era of molecular genetic diagnosis. O...

journal_title：JAMA ophthalmology

authors： Miraldi Utz V,Pfeifer W,Longmuir SQ,Olson RJ,Wang K,Drack AV

更新日期：2018-04-01 00:00:00

abstract：IMPORTANCE:Patching has been a mainstay in treating unilateral congenital cataract. However, its efficacy has not been rigorously assessed. OBJECTIVE:To examine the association between patching and visual acuity in a cohort of children treated for unilateral congenital cataract. DESIGN, SETTING, AND PARTICIPANTS:This...

journal_title：JAMA ophthalmology

authors： Drews-Botsch C,Celano M,Cotsonis G,Hartmann EE,Lambert SR,Infant Aphakia Treatment Study Group.

更新日期：2016-08-01 00:00:00

abstract：Importance:Mobility limitations arising from vision impairment (VI) can result in loss of independence and reduced quality of life. However, few data are available on the association between VI and mobility limitations at a population-based level, particularly in Asian populations. Objective:To assess the association ...

journal_title：JAMA ophthalmology

authors： Fenwick EK,Ong PG,Man RE,Cheng CY,Sabanayagam C,Wong TY,Lamoureux EL

更新日期：2016-10-01 00:00:00

abstract：IMPORTANCE:Further research is crucial to better understand the reason for falls in individuals with visual impairment (VI) and to develop appropriate fall prevention strategies. OBJECTIVE:To compare balance measures in individuals with normal vision, VI, and uncorrected refractive error (URE). DESIGN AND SETTING:Cro...

journal_title：JAMA ophthalmology

authors： Willis JR,Vitale SE,Agrawal Y,Ramulu PY

更新日期：2013-08-01 00:00:00

abstract：Importance:Mutations in the myocilin (MYOC) gene are the most common molecularly defined cause of primary open-angle glaucoma that typically occurs in patients with high intraocular pressures (IOP). One MYOC mutation, p.Gln368Ter, has been associated with as many as 1.6% of primary open-angle glaucoma cases that had a ...

journal_title：JAMA ophthalmology

authors： Alward WLM,van der Heide C,Khanna CL,Roos BR,Sivaprasad S,Kam J,Ritch R,Lotery A,Igo RP Jr,Cooke Bailey JN,Stone EM,Scheetz TE,Kwon YH,Pasquale LR,Wiggs JL,Fingert JH,NEIGHBORHOOD Consortium.

更新日期：2019-05-01 00:00:00

abstract：IMPORTANCE:Patients and clinicians need to accurately assess the risks and benefits of pars plana vitrectomy for proliferative diabetic retinopathy, but clinical trial data may not reflect real-world experience. OBJECTIVE:To prospectively audit the complications of vitrectomy for proliferative diabetic retinopathy and...

journal_title：JAMA ophthalmology

authors： Jackson TL,Johnston RL,Donachie PH,Williamson TH,Sparrow JM,Steel DH

更新日期：2016-01-01 00:00:00

abstract：Importance:The comparative clinical effectiveness of ranibizumab, aflibercept, and bevacizumab for the management of macular edema due to central retinal vein occlusion (CRVO) is unclear. Objective:To determine whether intravitreal aflibercept or bevacizumab compared with ranibizumab results in a noninferior mean chan...

journal_title：JAMA ophthalmology

authors： Hykin P,Prevost AT,Vasconcelos JC,Murphy C,Kelly J,Ramu J,Hounsome B,Yang Y,Harding SP,Lotery A,Chakravarthy U,Sivaprasad S,LEAVO Study Group.

更新日期：2019-08-29 00:00:00

abstract：IMPORTANCE:To facilitate comparative clinical outcome research in low vision rehabilitation, we must use patient-centered measurements that reflect clinically meaningful changes in visual ability. OBJECTIVE:To quantify the effects of currently provided low vision rehabilitation (LVR) on patients who present for outpat...

journal_title：JAMA ophthalmology

authors： Goldstein JE,Jackson ML,Fox SM,Deremeik JT,Massof RW,Low Vision Research Network Study Group.

更新日期：2015-07-01 00:00:00

abstract：IMPORTANCE:Anti-vascular endothelial growth factor (VEGF) medicines have revolutionized diabetic macular edema (DME) treatment. A recent randomized clinical trial comparing anti-VEGF agents for patients with decreased vision from DME found that at 1 year aflibercept (2.0 mg) achieved better visual outcomes than repacka...

journal_title：JAMA ophthalmology

authors： Ross EL,Hutton DW,Stein JD,Bressler NM,Jampol LM,Glassman AR,Diabetic Retinopathy Clinical Research Network.

更新日期：2016-08-01 00:00:00

abstract：Importance:To our knowledge, a set of well-defined diagnostic criteria is not yet developed for the diagnosis of Vogt-Koyanagi-Harada (VKH) disease. Objective:To develop and evaluate a set of diagnostic criteria for VKH disease using data from Chinese patients. Design, Setting, and Participants:This case-control stud...

journal_title：JAMA ophthalmology

authors： Yang P,Zhong Y,Du L,Chi W,Chen L,Zhang R,Zhang M,Wang H,Lu H,Yang L,Zhuang W,Yang Y,Xing L,Feng L,Jiang Z,Zhang X,Wang Y,Zhong H,Jiang L,Zhao C,Li F,Cao S,Liu X,Chen X,Shi Y,Zhao W,Kijlstra A

更新日期：2018-09-01 00:00:00

abstract：Importance:Preservation of peripheral visual field (VF) is considered an advantage for anti-vascular endothelial growth factor agents compared with panretinal photocoagulation (PRP) for treatment of proliferative diabetic retinopathy. Long-term data on VF are important when considering either treatment approach. Objec...

journal_title：JAMA ophthalmology

authors： Maguire MG,Liu D,Glassman AR,Jampol LM,Johnson CA,Baker CW,Bressler NM,Gardner TW,Pieramici D,Stockdale CR,Sun JK,DRCR Retina Network.

更新日期：2020-03-01 00:00:00

abstract：IMPORTANCE:The optic disc pit (ODP) has been considered a region of localized susceptibility to the damage of glaucoma. OBJECTIVE:To determine whether the rate of retinal nerve fiber layer (RNFL) thinning differs according to the presence and structural characteristics of an ODP in primary open-angle glaucoma. DESIGN...

journal_title：JAMA ophthalmology

authors： Lee SH,Lee EJ,Kim TW

更新日期：2015-10-01 00:00:00

abstract：Importance:The frequency of anti-vascular endothelial growth factor (VEGF) injections has grown exponentially with the introduction of bevacizumab, ranibizumab, and most recently aflibercept. The cost associated with these medications has garnered significant national attention, warranting a granular analysis of their ...

journal_title：JAMA ophthalmology

authors： Berkowitz ST,Sternberg P Jr,Feng X,Chen Q,Patel S

更新日期：2019-06-20 00:00:00

abstract：IMPORTANCE:Medication persistence is an important factor for treatment effect in patients with glaucoma. Evaluating risk factors for refill discontinuation might be helpful for improving persistence and preventing blindness in patients with glaucoma. OBJECTIVES:To estimate the persistence rate with topical glaucoma me...

journal_title：JAMA ophthalmology

authors： Hwang DK,Liu CJ,Pu CY,Chou YJ,Chou P

更新日期：2014-12-01 00:00:00

abstract：Importance:Uveitis has been associated with psoriatic arthritis, but to our knowledge, the relationship between uveitis and psoriasis is unsettled among researchers. Objective:To evaluate the risk of incident uveitis among people with psoriasis. Design, Setting, and Participants:This nationwide, retrospective cohort ...

journal_title：JAMA ophthalmology

authors： Chi CC,Tung TH,Wang J,Lin YS,Chen YF,Hsu TK,Wang SH

更新日期：2017-05-01 00:00:00

abstract：IMPORTANCE:A large number of genes can cause inherited retinal degenerations when mutated. It is important to identify the cause of disease for a better disease prognosis and a possible gene-specific therapeutic intervention. OBJECTIVE:To identify the cause of disease in families with nonsyndromic retinitis pigmentosa...

journal_title：JAMA ophthalmology

authors： Shevach E,Ali M,Mizrahi-Meissonnier L,McKibbin M,El-Asrag M,Watson CM,Inglehearn CF,Ben-Yosef T,Blumenfeld A,Jalas C,Banin E,Sharon D

更新日期：2015-03-01 00:00:00

abstract：Importance:The ocular surface is continuously exposed to the environment. Although studies have focused on associations between outdoor environmental conditions and dry eye, information on associations between the indoor environment and dry eye is lacking. Objective:To determine associations between the indoor environ...

journal_title：JAMA ophthalmology

authors： Huang A,Janecki J,Galor A,Rock S,Menendez D,Hackam AS,Jeng BH,Kumar N

更新日期：2020-08-01 00:00:00

abstract：Importance:The coronavirus disease 2019 pandemic illustrates the increasingly important role of telemedicine as a method of clinician-patient interaction. However, electronic applications (apps) for the testing of ophthalmology vital signs, such as visual acuity, can be published and used without any verification of ac...

journal_title：JAMA ophthalmology

authors： Steren BJ,Young B,Chow J

更新日期：2021-01-14 00:00:00

abstract：IMPORTANCE:Acanthamoeba keratitis is a debilitating eye disease that requires effective topical drug therapy. Currently, there is no standard in vitro test to evaluate anti-Acanthamoeba drugs. OBJECTIVE:To develop a practical in vitro complete-kill assay to assess anti-Acanthamoeba drugs. DESIGN AND SETTING:Isolates ...

journal_title：JAMA ophthalmology

authors： Kowalski RP,Abdel Aziz S,Romanowski EG,Shanks RM,Nau AC,Raju LV

更新日期：2013-11-01 00:00:00

abstract：Importance:Visual impairment and visual disorders often co-occur with other chronic conditions. Understanding patterns of multimorbidity is important for reducing health care use and improving health outcomes. Objective:To identify chronic condition patterns and their association with visual impairment and health care...

journal_title：JAMA ophthalmology

authors： Zheng DD,Christ SL,Lam BL,Feaster DJ,McCollister K,Lee DJ

更新日期：2020-04-01 00:00:00