Abstract：
BACKGROUND:Serial surveillance of liver iron concentration (LIC) provides guidance for chelation therapy in patients with iron overload. The diagnosis of iron overload traditionally relies on core liver biopsy, which is limited by invasiveness, sampling error, cost and general poor acceptance by pediatric patients and parents. Thus noninvasive diagnostic methods such as MRI are highly attractive for quantification of liver iron concentration. OBJECTIVE:To compare two MRI-based methods for liver iron quantification in children. MATERIALS AND METHODS:64 studies on 48 children and young adults (age range 4-21 years) were examined by gradient recalled echo (GRE) R2* and spin-echo R2 MRI at 1.5T to evaluate liver iron concentration. Scatter plots and Bland-Altman difference plots were generated to display and assess the relationship between the methods. RESULTS:With the protocols used in this investigation, Bland-Altman agreement between the methods is best when LIC is <20 mg/g dry tissue. Scatter plots show that all values with LIC <20 mg/g dry tissue fall within the 95% prediction limits. CONCLUSION:Liver iron concentration as determined by the R2* and R2 MR methods is statistically comparable, with no statistical difference between these methods for LIC <20 mg/g.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Serai SD,Fleck RJ,Quinn CT,Zhang B,Podberesky DJdoi
10.1007/s00247-015-3378-9subject
Has Abstractpub_date
2015-10-01 00:00:00pages
1629-34issue
11eissn
0301-0449issn
1432-1998pii
10.1007/s00247-015-3378-9journal_volume
45pub_type
杂志文章abstract：:We present an unusual case of severe hydranencephaly in a term infant who presented with the following additional unique features, which were discovered on CT, MRI and MR angiography examinations: (1) occlusion of the bilateral posterior cerebral arteries, (2) absence of the occipital lobes, (3) an ovoid calcified mas...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-010-1894-1
更新日期：2011-02-01 00:00:00
abstract：:We report an 8-month-old girl with portal hypertension secondary to biliary atresia. The decision to treat with TIPS was made at the age of 8 months due to recurrent variceal bleeding. The procedure was carried out with a 6-mm bare stent due to her small size. Radiological follow-up with Doppler US showed gradual sten...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-009-1211-z
更新日期：2009-07-01 00:00:00
abstract：:A case is presented in which chronic renal failure led to intense visceral calcification, mainly to the lungs and heart. The discovery of cardiac calcifications on plain chest radiographs is exceedingly rare in renal patients. Punctate calcific deposits with an almost homogeneous distribution throughout the cardiac mu...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02386824
更新日期：1986-01-01 00:00:00
abstract：:Extensive vascular calcification in an 8-year-old girl with perinatally acquired AIDS is reported. Complicating factors included cardiomyopathy, chronic lung disease, disseminated Mycobacterium avium complex (MAC), and wasting syndrome with total nutrition dependence. Plain abdominal films and CT of the abdomen immedi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01395718
更新日期：1996-01-01 00:00:00
abstract：:We describe the ultrasonography, the contrast-enhanced computed tomography and the magnetic resonance imaging of subcutaneous fat necrosis in a newborn infant. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-005-0086-x
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Takayasu's arteritis (TA) is a chronic idiopathic inflammatory disease affecting primarily the aorta, its proximal branches and the pulmonary arteries. OBJECTIVES:To retrospectively review the angiograms of children with TA so as to describe the patterns of vascular involvement. PATIENTS AND METHODS:Twenty...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-002-0817-1
更新日期：2003-04-01 00:00:00
abstract：:Hydranencephaly is an encephaloclastic central nervous system disorder characterised by severe destruction of the cerebral hemispheres with preservation of posterior fossa structures. We present MRI and neurosonography features of a unique case of hydranencephaly involving cerebellum (in the form of complete liquefact...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-010-1749-9
更新日期：2011-02-01 00:00:00
abstract：:A variety of lesions occur in the pediatric salivary glands. With modern imaging techniques such as Doppler sonography, helical CT, and MRI, identification of a specific etiology is often possible. Knowledge of clinical information, normal anatomy, and imaging characteristics of salivary gland pathology are essential ...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-009-1232-7
更新日期：2009-07-01 00:00:00
abstract：:An extralobar pulmonary sequestration in an infant was diagnosed by ultrasound. The sequestration appeared as an echogenic mass interpositioned between the liver and the right lung. The main feeding vessel of the sequestration was demonstrable. Ultrasound should be the first diagnostic modality used for evaluation of ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01042246
更新日期：1984-01-01 00:00:00
abstract：BACKGROUND:New developments in processing of digital radiographs (DR), including multi-frequency processing (MFP), allow optimization of image quality and radiation dose. This is particularly promising in children as they are believed to be more sensitive to ionizing radiation than adults. OBJECTIVE:To examine whether...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-012-2385-3
更新日期：2012-09-01 00:00:00
abstract：:Cholelithiasis is very rare in the newborn infant and is usually not recognized until surgery or autopsy following perforation of the biliary tree. Two premature infants had calcified gallstones on abdominal radiographs. In one patient portal vein thrombosis was also present. The other had been treated with total pare...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF00973193
更新日期：1982-01-01 00:00:00
abstract：:Mass-like renal lesions in children occur in a diverse spectrum of conditions including benign and malignant neoplasm, infection, infarction, lymphatic malformation, and traumatic injury. Although mass-like renal lesions can sometimes be suspected on plain radiographs and evaluated with US in children, subsequent CT i...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-007-0548-4
更新日期：2007-09-01 00:00:00
abstract：:A 4-year-old boy with bilateral optic sheath enlargement and progressive optic atrophy and blindness is presented. Computed tomography demonstrated hydrocephalus and enlargement of the optic nerve sheath complex. The child died during an attempted repair of hypoplastic atrioventricular valves. Autopsy demonstrated a p...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470050518
更新日期：1998-12-01 00:00:00
abstract：:We present a case of neonatal acute gastric outlet obstruction related to prostaglandin-induced gastric foveolar hyperplasia, which developed following infusion of prostaglandin E1 (PGE1) for treatment of hypoplastic left heart syndrome. Abdominal distension occurred after administration of PGE1 in a cumulative dose o...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470050064
更新日期：1997-01-01 00:00:00
abstract：:Two cases are presented of children who demonstrated complete absence of bone marrow signal on MR imaging of the spine following bone marrow transplantation. The possible causes for these appearances are discussed. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02018628
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Excessive cervical flexion-extension accompanying mild to severe impact injuries can lead to C2 synchondrosal fractures in young children. OBJECTIVE:To characterize and classify C2 synchondrosal fracture patterns. MATERIALS AND METHODS:We retrospectively reviewed imaging and medical records of children who...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-014-3224-5
更新日期：2015-06-01 00:00:00
abstract：:Antenatal detection of mesoblastic nephroma by US is possible. Reviewing the literature, we found 19 previously reported cases, only 1 of which underwent prenatal MRI. We present a further case diagnosed by US and confirmed with MRI. The imaging findings and differential diagnoses are discussed. Early and correct dete...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470050033
更新日期：2000-03-01 00:00:00
abstract：:Clavicle fractures are the most common bony injury that occurs during the delivery process. We present a case of medial clavicular physeal fracture mimicking sternoclavicular dislocation diagnosed by ultrasound (US) in a neonate. The infant presented to our clinic at 12 days old with improving left upper extremity pse...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-019-04583-2
更新日期：2020-04-01 00:00:00
abstract：:The accessory parotid gland, a little-known and seldom-mentioned anatomical variant, is a nodule of normal salivary tissue separate from the main parotid gland, located on the masseter muscle and connected to the Stensen duct at that level. It can be the site of both congenital and acquired lesions. ...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-005-0034-9
更新日期：2006-01-01 00:00:00
abstract：:The experience from 123 pediatric MRI examinations disclosed several different types of artifacts and age-related variants that could have caused pitfalls in MRI interpretation. Artifacts were caused by metallic objects, patient touching the RF coil, and patient motion. The potential pitfalls are caused by the MRI var...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02388605
更新日期：1985-01-01 00:00:00
abstract：:Primary non-Hodgkin's lymphoma of the skull base presenting with neuro-ophthalmologic abnormalities or cavernous sinus involvement is very rare in children. We have found only 13 reported cases of cavernous sinus involvement by lymphoma [1]. We report the case of the youngest child diagnosed with Burkitt's lymphoma of...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01387317
更新日期：1996-01-01 00:00:00
abstract：:A 10-year old, mentally and physically normally developed girl complained of back pain following an accident. Radiological findings revealed an inhomogeneous, coarse osteosclerosis along the endplates and posterior parts of the ovoid shaped vertebral bodies, in the proximal and distal femora-, proximal humeri and tibi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02387669
更新日期：1989-01-01 00:00:00
abstract：:Inflammatory bowel diseases (IBDs), including Crohn disease (CD) and ulcerative colitis (UC), often affect children and adolescents. Their diagnosis is based on the integration of clinical, biological, endoscopic, histological and radiological data. The paediatric radiologist may help the clinician in many ways. In ch...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-007-0573-3
更新日期：2007-11-01 00:00:00
abstract：:A 1-year-old girl with unilateral proptosis was found to have primary orbital lymphomatoid granulomatosis - a condition rarely occurring in children. This multisystem angiocentric, angiodestructive, lymphoproliferative disease typically involves the lungs, with ocular involvement being extremely uncommon. Our case ser...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-014-3206-7
更新日期：2015-07-01 00:00:00
abstract：:Part 1 of this series of two articles describes conventional and advanced MRI techniques that are useful for evaluating brainstem pathologies. In addition, it provides a review of the embryology, normal progression of myelination, and clinically and radiologically salient imaging anatomy of the normal brainstem. Final...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-020-04953-1
更新日期：2021-02-01 00:00:00
abstract：:Vasoactive intestinal polypeptide (VIP) secreting neural crest tumours are an uncommon but important treatable cause of intractable childhood diarrhoea. The radiological appearances of two cases are presented with a review of radiological findings in childhood VIP secreting neural crest tumours. Twenty eight cases of ...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/BF02011377
更新日期：1990-01-01 00:00:00
abstract：:A case of hypertrophic osteoarthropathy in a 5-year-old Saudi boy is presented. The child developed painful joints, was found to have clubbing of fingers and radiologically hypertrophic osteoarthropathy was demonstrated. The underlying cause of the condition was ingestion of animal fat in infancy, with a history of gh...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02019076
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:It has been suggested that the pelvis should not be habitually included on abdominal CT examinations, but the potential benefit of such a practice in childhood abdominal malignancies is unknown. OBJECTIVE:To estimate the yield and potential diagnostic benefit of abnormal findings on CT of the pelvis in chil...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-005-0053-6
更新日期：2006-03-01 00:00:00
abstract：:Hypertension due to transplant renal artery stenosis was treated with percutaneous transluminal angioplasty (PTA) in 6 children. 8 angioplasties were performed and the follow-up period varied between 3 and 66 months (average 23 months). The stenoses were located at the site of anastomosis in 4 children and distal to t...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02012999
更新日期：1992-01-01 00:00:00
abstract：:The radiological manifestations of an unusual spondyloepiphyseal dysplasia have been observed in a girl. A peculiar epi-metaphyseal involvement that is "cone shaped epiphyses" appears to be the major feature. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02388164
更新日期：1987-01-01 00:00:00
