Abstract:
:Human subgenual anterior cingulate cortex (sACC) is involved in affective experiences and fear processing. Functional neuroimaging studies view it as a homogeneous cortical entity. However, sACC comprises several distinct cyto- and receptorarchitectonical areas: 25, s24, s32, and the ventral portion of area 33. Thus, we hypothesized that the areas may also be connectionally and functionally distinct. We performed structural post mortem and functional in vivo analyses. We computed probabilistic maps of each area based on cytoarchitectonical analysis of ten post mortem brains. Maps, publicly available via the JuBrain atlas and the Anatomy Toolbox, were used to define seed regions of task-dependent functional connectivity profiles and quantitative functional decoding. sACC areas presented distinct co-activation patterns within widespread networks encompassing cortical and subcortical regions. They shared common functional domains related to emotion, perception and cognition. A more specific analysis of these domains revealed an association of s24 with sadness, and of s32 with fear processing. Both areas were activated during taste evaluation, and co-activated with the amygdala, a key node of the affective network. s32 co-activated with areas of the executive control network, and was associated with tasks probing cognition in which stimuli did not have an emotional component. Area 33 was activated by painful stimuli, and co-activated with areas of the sensorimotor network. These results support the concept of a connectional and functional specificity of the cyto- and receptorarchitectonically defined areas within the sACC, which can no longer be seen as a structurally and functionally homogeneous brain region.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Palomero-Gallagher N,Eickhoff SB,Hoffstaedter F,Schleicher A,Mohlberg H,Vogt BA,Amunts K,Zilles Kdoi
10.1016/j.neuroimage.2015.04.053subject
Has Abstractpub_date
2015-07-15 00:00:00pages
177-90eissn
1053-8119issn
1095-9572pii
S1053-8119(15)00353-5journal_volume
115pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::Many studies have investigated the temporal properties of BOLD signal responses to task performance in regions of interest, often noting significant departures from the conventionally modelled response shape, and significant variation between regions. However, these investigations are rarely extended across the whole ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.09.006
更新日期:2007-01-01 00:00:00
abstract::Recent experiments suggest that T1 relaxation in the rotating frame (T1ρ) detects localized metabolic changes in the human visual cortex induced by a flashing checkerboard task. Possible sources of the T1ρ signal include pH, glucose, and glutamate concentrations as well as changes in cerebral blood volume. In this stu...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.01.042
更新日期:2014-07-15 00:00:00
abstract:UNLABELLED:The role of the primary motor cortex (M1) in tasks involving action words remains controversial. Therefore, we investigated whether the previously reported involvement of M1 in processing of action words results from the semantic representation of action words per se, or if M1 activation may actually depend ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.03.035
更新日期:2007-01-01 00:00:00
abstract::Automated segmentation of brain MRI scans into tissue classes is commonly used for the assessment of multiple sclerosis (MS). However, manual correction of the resulting brain tissue label maps by an expert reader remains necessary in many cases. Since automated segmentation data awaiting manual correction are "missin...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.06.037
更新日期:2015-10-01 00:00:00
abstract::Although much is now known about eye movement detection, little is known about the higher cognitive processes involved in joint attention. We developed video stimuli which when watched, engender an experience of joint attention in the observer. This allowed us to compare an experience of joint attention to nonjoint at...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2004.10.047
更新日期:2005-03-01 00:00:00
abstract::Multivariate pattern analysis can be used to decode the orientation of a viewed grating from fMRI signals in early visual areas. Although some studies have reported identifying multiple sources of the orientation information that make decoding possible, a recent study argued that orientation decoding is only possible ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.11.066
更新日期:2016-02-15 00:00:00
abstract::Small-world organization is known to be a robust and consistent network architecture, and is a hallmark of the structurally and functionally connected human brain. However, it remains unknown if the same organization is present in directed influence brain networks whose connectivity is inferred by the transfer of info...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.11.007
更新日期:2011-02-14 00:00:00
abstract::Working memory is a fundamental cognitive building block involved in the short-term maintenance and transformation of information. In neuropsychological studies, working memory has been shown to be of limited capacity; however, the neurophysiological concomitants of this capacity limitation have not been explored. In ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0338
更新日期:1998-05-01 00:00:00
abstract::An influential framework suggests that the central nucleus of the amygdala (CeA) is involved in phasic responses to threat, while the bed nucleus of the stria terminalis (BNST) mediates sustained anxiety. However, this model has been questioned, proposing that the role of the BNST is not limited to sustained threat co...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.10.054
更新日期:2018-02-01 00:00:00
abstract::Mäkinen et al. [Mäkinen, V., Tiitinen, H., May, P., 2005. Auditory event-related responses are generated independently of ongoing brain activity. Neuroimage 24, 961-968] suggest the use of amplitude variance to distinguish the evoked response from phase reset. Because their data do not exhibit a drop in amplitude vari...
journal_title:NeuroImage
pub_type: 评论,杂志文章
doi:10.1016/j.neuroimage.2005.08.041
更新日期:2006-02-01 00:00:00
abstract::Reconstruction of white matter tracts based on diffusion tensor imaging (DTI) is currently widely used in clinical research. This reconstruction allows us to identify coordinates of specific white matter tracts and to investigate their anatomy. Fiber reconstruction, however, relies on manual identification of anatomic...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.04.241
更新日期:2008-08-15 00:00:00
abstract::Medial temporal lobe (MTL) structures are crucial for episodic memory. However, it remains unclear how these structures are involved in encoding and retrieval processes as a function of recollection and familiarity. To better elucidate MTL organization of these two processes, we implemented an fMRI protocol in which b...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.06.086
更新日期:2011-10-15 00:00:00
abstract::Magnetic susceptibility based (T(2)* weighted) contrast in MRI at high magnetic field strength is of great value in research on brain structure and cortical architecture, but its use is hampered by the low signal-to-noise ratio (SNR) efficiency of the conventional spoiled gradient echo sequence (GRE) leading to long s...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.03.046
更新日期:2011-06-15 00:00:00
abstract::Despite motion artifacts are a major source of noise in fNIRS infant data, how to approach motion correction in this population has only recently started to be investigated. Homer2 offers a wide range of motion correction methods and previous work on simulated and adult data suggested the use of Spline interpolation a...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.06.056
更新日期:2019-10-15 00:00:00
abstract::A key challenge for cognitive neuroscience is deciphering the representational schemes of the brain. Stimulus-feature-based encoding models are becoming increasingly popular for inferring the dimensions of neural representational spaces from stimulus-feature spaces. We argue that such inferences are not always valid b...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2018.03.041
更新日期:2018-07-01 00:00:00
abstract::Breathing carbogen (5% CO2 / 95% O2) dramatically increases cerebral blood flow (CBF), which induces a blood oxygenation level dependent (BOLD) related vascular signal change due to the concomitantly increased oxyhemoglobin concentration in the veins. However, carbogen often causes discomfort due to its forced strong ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.07.008
更新日期:2008-10-15 00:00:00
abstract::Over the past decade fMRI researchers have developed increasingly sensitive techniques for analyzing the information represented in BOLD activity. The most popular of these techniques is linear classification, a simple technique for decoding information about experimental stimuli or tasks from patterns of activity acr...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2010.07.073
更新日期:2011-05-15 00:00:00
abstract::According to recent research on language comprehension, the semantic features of a text are not the only determinants of whether incoming information is understood as consistent. Listeners' pre-existing affective states play a crucial role as well. The current fMRI experiment examines the effects of happy and sad mood...
journal_title:NeuroImage
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.neuroimage.2014.09.008
更新日期:2014-12-01 00:00:00
abstract::The relationship between structure and function in the human brain is well established, but not yet well characterised. Large-scale biophysical models allow us to investigate this relationship, by leveraging structural information (e.g. derived from diffusion tractography) in order to couple dynamical models of local ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.02.063
更新日期:2018-07-01 00:00:00
abstract::Event-related potentials (ERPs) are noninvasive measures of human brain activity that index a range of sensory, cognitive, affective, and motor processes. Despite their broad application across basic and clinical research, there is little standardization of ERP paradigms and analysis protocols across studies. To addre...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117465
更新日期:2021-01-15 00:00:00
abstract::Both affective neuroscience and decision science focus on the role of emotions in decisions. Regret and disappointment are emotions experienced with negative decision outcomes. The present research examines the neural substrates of regret and disappointment as well as the role of regret and disappointment in decision ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.06.006
更新日期:2009-10-01 00:00:00
abstract::Although the long-range temporal correlation (LRTC) of the amplitude fluctuations of neuronal EEG/MEG oscillations is widely acknowledged, the majority of studies to date have been performed in sensor space, disregarding the mixing effects implied by volume conduction and confounding noise. While the effect of mixing ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.05.041
更新日期:2014-10-01 00:00:00
abstract::The ability to regulate emotions is essential for adaptive behavior. This ability is suggested to be mediated by the connectivity between prefrontal brain regions and the amygdala. Yet, it is still unknown whether the ability to regulate emotions can be trained by using a non-emotional procedure, such as the recruitme...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.10.069
更新日期:2016-01-15 00:00:00
abstract::The core concept within the field of brain mapping is the use of a standardized, or "stereotaxic", 3D coordinate frame for data analysis and reporting of findings from neuroimaging experiments. This simple construct allows brain researchers to combine data from many subjects such that group-averaged signals, be they s...
journal_title:NeuroImage
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.neuroimage.2012.01.024
更新日期:2012-08-15 00:00:00
abstract::Language lateralization based on functional magnetic resonance imaging (fMRI) is often used in clinical neurological settings. Currently, interpretation of the distribution, pattern and extent of language activation can be heavily dependent on the chosen statistical threshold. The aim of the present study was to 1) te...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.01.059
更新日期:2010-05-01 00:00:00
abstract::We report on the initial imaging findings with a new technique for the simultaneous and continuous acquisition of functional MRI data and EEG recording. Thirty-seven stereotyped interictal epileptiform discharges (spikes) were identified on EEG recorded continuously during the fMRI acquisition on a patient with epilep...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2001.0853
更新日期:2001-09-01 00:00:00
abstract::General cognitive ability (GCA) has substantial explanatory power for behavioral and health outcomes, but its cortical substrate is still not fully established. GCA is highly polygenic and research to date strongly suggests that its cortical substrate is highly polyregional. We show in map-based and region-of-interest...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.01.049
更新日期:2016-04-01 00:00:00
abstract::Facial displays of emotions can help to infer the mental states of other individuals. However, the expectations we generate on the basis of people's emotions can mismatch their actual behaviour in certain circumstances, which generates conflict. In the present study, we explored the neural mechanisms of emotional conf...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.08.039
更新日期:2011-01-15 00:00:00
abstract::Rodent studies suggest that prefrontal dopamine neurotransmission plays an important role in the neural processing of psychosocial stress. Human studies investigating stress-induced changes in dopamine levels, however, have focused solely on striatal dopamine transmission. The aim of this study was to investigate in v...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.07.030
更新日期:2011-10-15 00:00:00
abstract::Stimulation of acupuncture point Pc6, located above the median nerve, has been shown to be effective in treating nausea and vomiting. It has also frequently been reported to cause a heart rate reduction. The mechanism behind this autonomic reaction has not been clarified, so far. We combined brainstem-sensitive functi...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.12.045
更新日期:2012-03-01 00:00:00