Abstract:
:Although much is now known about eye movement detection, little is known about the higher cognitive processes involved in joint attention. We developed video stimuli which when watched, engender an experience of joint attention in the observer. This allowed us to compare an experience of joint attention to nonjoint attention within an fMRI scanning environment. Joint attention was associated with activity in the ventromedial frontal cortex, the left superior frontal gyrus (BA10), cingulate cortex, and caudate nuclei. The ventromedial frontal cortex has been consistently shown to be activated during mental state attribution tasks. BA10 may serve a cognitive integration function, which in this case seems to utilize a perception-action matching process. The activation we identified in BA10 overlaps with a location of increased grey matter density that we recently found to be associated with autistic spectrum disorder. This study therefore constitutes evidence that the neural substrate of joint attention also serves a mentalizing function. The developmental failure of this substrate in the left anterior frontal lobe may be important in the etiology of autistic spectrum disorder.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Williams JH,Waiter GD,Perra O,Perrett DI,Whiten Adoi
10.1016/j.neuroimage.2004.10.047keywords:
subject
Has Abstractpub_date
2005-03-01 00:00:00pages
133-40issue
1eissn
1053-8119issn
1095-9572pii
S1053-8119(04)00658-5journal_volume
25pub_type
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