Abstract：
:Medial temporal lobe (MTL) structures are crucial for episodic memory. However, it remains unclear how these structures are involved in encoding and retrieval processes as a function of recollection and familiarity. To better elucidate MTL organization of these two processes, we implemented an fMRI protocol in which both encoding and retrieval of words were scanned in 21 healthy adults. During encoding, subjects were requested to bind each word to an emotional context (pleasant or unpleasant). Retrieval consisted of a Remember/Know procedure in two stages: first, subjects had to recognize the word, followed by the retrieval of the associated emotional context. fMRI data were reported in eight manually delineated MTL regions of interest (in the head, body and tail of the hippocampus, the entorhinal, perirhinal and parahippocampal cortices, the amygdala and the temporopolar cortex). Results obtained in 19 subjects showed four MTL patterns of activity consisting in activations of parahippocampal cortex and hippocampus in episodic encoding and retrieval and perirhinal cortex involvement in familiarity. These results are in line with the Binding of Item and Context (BIC) model predictions. Additionally, some new findings specified the familiarity MTL neural substrate by showing precise entorhinal activations during retrieval of familiar words, as well as hippocampal and amygdala deactivations in encoding of these words. Finally, we emphasize that among all four memory processes, episodic retrieval (recollection effect) was the only one eliciting strong bilateral activations in all MTL structures. These results should be considered for future studies on MTL dysfunction in patients with temporal lobe damage.
journal_name
Neuroimagejournal_title
NeuroImageauthors
de Vanssay-Maigne A,Noulhiane M,Devauchelle AD,Rodrigo S,Baudoin-Chial S,Meder JF,Oppenheim C,Chiron C,Chassoux Fdoi
10.1016/j.neuroimage.2011.06.086subject
Has Abstractpub_date
2011-10-15 00:00:00pages
1131-8issue
4eissn
1053-8119issn
1095-9572pii
S1053-8119(11)00751-8journal_volume
58pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract：:Neuroimaging studies have identified regional brain dysfunctions in schizophrenia, but their dynamic consequences remain unclear. This study reports electrophysiological evaluation of medicated schizophrenic patients during performance of the Wisconsin Card Sorting Test. Using event-related potentials (ERPs), averaged...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/s1053-8119(03)00240-4
更新日期：2003-08-01 00:00:00
abstract：:Animal studies suggest that N-methyl-D-aspartate receptor (NMDAR) dependent signalling in limbic and prefrontal regions is critically involved in both cognitive and emotional functions. In humans, ketamine-induced transient, and disorder associated chronic NMDAR hypofunction (i.e. in schizophrenia) has been associated...
journal_title：NeuroImage
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.neuroimage.2017.02.049
更新日期：2017-04-15 00:00:00
abstract：:Facial emotions express our internal states and are fundamental in social interactions. Here we explore whether the repetition of unattended facial emotions builds up a predictive representation of frequently encountered emotions in the visual system. Participants (n=24) were presented peripherally with facial stimuli...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.10.041
更新日期：2012-02-01 00:00:00
abstract：:Though the hippocampus has been associated with encoding and retrieval processes in episodic memory, the precise nature of its involvement in working memory has yet to be determined. This functional magnetic resonance imaging (fMRI) study employed a verbal working memory paradigm that allows for the within-subject com...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：10.1016/j.neuroimage.2005.01.038
更新日期：2005-05-01 00:00:00
abstract：:Brain imaging studies have suggested a critical role for prefrontal cortex in working memory (WM) tasks that require both maintainenance and manipulation of information over time in delayed-response WM tasks. In the present study, functional magnetic resonance imaging (fMRI) was used to examine whether prefrontal area...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1006/nimg.1998.0404
更新日期：1999-02-01 00:00:00
abstract：:Q-ball imaging has the ability to discriminate multiple intravoxel fiber populations within regions of complex white matter architecture. This information can be used for fiber tracking; however, diffusion MR is susceptible to noise and multiple other sources of uncertainty affecting the measured orientation of fiber ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2007.08.021
更新日期：2008-01-01 00:00:00
abstract：:Recent work has shown a dramatic contrast between GM and WM in gradient echo phase images at high field (7 T). Although this contrast is key to the exploitation of phase in imaging normal and pathological tissue, its origin remains contentious. Several sources for this contrast have been considered including iron cont...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2009.12.052
更新日期：2010-04-01 00:00:00
abstract：:Recent atlases of the cortical surface are based on a modelization of the cerebral cortex as a topological sphere. This captures effectively its organization as a regular bidimensional sheet of layers parallel to the surface and with perpendicular cortical columns. Yet, while in the vertical direction cortices are alm...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2003.07.008
更新日期：2003-11-01 00:00:00
abstract：:This study investigates neural correlates of music-evoked fear and joy with fMRI. Studies on neural correlates of music-evoked fear are scant, and there are only a few studies on neural correlates of joy in general. Eighteen individuals listened to excerpts of fear-evoking, joy-evoking, as well as neutral music and ra...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.05.008
更新日期：2013-11-01 00:00:00
abstract：:White matter thalamo-cortical fibers allow the communication of distant brain regions by carrying neuronal signals. Mapping non-invasively the information flow within white matter fibers is regarded so far as impossible. We investigated here whether information flow propagating along thalamo-cortical fibers can be det...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2012.01.054
更新日期：2012-04-02 00:00:00
abstract：INTRODUCTION:To investigate in vivo differences in the distribution of alpha4beta2 subtypes of nAChR using the ligand (123)I-5-Iodo-3-[2(S)-2-azetidinylmethoxy] pyridine (5IA-85380) and single photon emission computed tomography (SPECT) in DLB and similarly aged controls. METHODS:Thirty-one subjects (15 DLB and 16 con...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2008.01.010
更新日期：2008-04-15 00:00:00
abstract：:Despite the immense ongoing efforts to map brain functional connections and organizations with resting-state functional MRI (rsfMRI), the mechanisms governing the temporally coherent rsfMRI signals remain unclear. In particular, there is a lack of direct evidence regarding the morphological foundation and plasticity o...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.08.037
更新日期：2014-01-01 00:00:00
abstract：:The finding of a multisensory representation of actions in a premotor area of the monkey brain suggests that similar multimodal action-matching mechanisms may also be present in humans. Based on the existence of an audiovisual mirror system, we investigated whether sounds referring to actions that can be performed by ...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：10.1016/j.neuroimage.2004.09.025
更新日期：2005-02-01 00:00:00
abstract：:In infants, the fontanels and sutures as well as conductivity of the skull influence the volume currents accompanying primary currents generated by active neurons and thus the associated electroencephalography (EEG) and magnetoencephalography (MEG) signals. We used a finite element method (FEM) to construct a realisti...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.03.017
更新日期：2013-08-01 00:00:00
abstract：:Cortical plasticity is thought to occur following continuous barrage of nociceptive afferent signals to the brain. Hence, chronic pain is presumed to induce anatomical and physiological changes in the brain over time. Inherent factors, some pre-dating the onset of chronic pain, may also contribute to brain abnormaliti...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2010.12.013
更新日期：2011-03-01 00:00:00
abstract：:Global neuronal workspace theory predicts that damage to long-distance white matter (WM) tracts should impair access to consciousness during the perception of brief stimuli. To address this issue, we studied visual backward masking in 18 patients at the very first clinical stage of multiple sclerosis (MS), a neurologi...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2008.08.024
更新日期：2009-01-15 00:00:00
abstract：:The purpose of this study was to investigate whether current or lifetime alcohol intake is related to focal gray and white matter in healthy non-alcohol-dependent drinkers, and, if so, whether these densities are related to functional brain activity associated with visual attention. Voxel-based morphometric analyses o...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2005.01.036
更新日期：2005-06-01 00:00:00
abstract：:Examining the brain at rest is a powerful approach used to understand the intrinsic properties of typical and disordered human brain function, yet task-free paradigms are associated with greater head motion, particularly in young and/or clinical populations such as autism spectrum disorder (ASD) and attention-deficit/...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.117524
更新日期：2021-01-15 00:00:00
abstract：:The nature and origin of fMRI resting state fluctuations and connectivity are still not fully known. More detailed knowledge on the relationship between resting state patterns and brain function may help to elucidate this matter. We therefore performed an in depth study of how resting state fluctuations map to the wel...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.09.060
更新日期：2014-01-01 00:00:00
abstract：:Increasing evidence suggests that sleep spindles are involved in memory consolidation, but few studies have investigated the effects of learning on brain responses associated with spindles in humans. Here we used simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) during sleep to...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2019.03.051
更新日期：2019-07-15 00:00:00
abstract：:While the role of synchronized oscillatory activity in the gamma-band frequency range for conscious perception is well established in the visual domain, there is limited evidence concerning neurophysiological mechanisms in conscious auditory perception. In the current study, we addressed this issue with 64-channel EEG...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.06.012
更新日期：2014-10-15 00:00:00
abstract：:Openness is a personality trait reflecting absorption in sensory experience, preference for novelty, and creativity, and is thus considered a driving force of human evolution. At the brain level, a relation between openness and dopaminergic circuits has been proposed, although evidence to support this hypothesis is la...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.09.017
更新日期：2015-01-01 00:00:00
abstract：:We sought to determine the feasibility of directly studying neural tissue activity by analysis of differential phase shifts in MRI signals that occurred when trickle currents were applied to a bath containing active or resting neural tissue. We developed a finite element bidomain model of an aplysia abdominal ganglion...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2010.04.005
更新日期：2010-08-01 00:00:00
abstract：:Proportional scaling models are often used in functional imaging studies to remove confounding of local signals by global effects. It is generally assumed that global effects are uncorrelated with experimental conditions. However, when the global effect is estimated by the global signal, defined as the intracerebral a...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.03.025
更新日期：2006-08-01 00:00:00
abstract：:The suggested revision of the NINCDS-ADRDA criterion for the diagnosis of Alzheimer's disease (AD) includes at least one abnormal biomarker among magnetic resonance imaging (MRI), positron emission tomography (PET) and cerebrospinal fluid (CSF). We aimed to investigate if the combination of baseline MRI and CSF could ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2012.04.056
更新日期：2012-08-01 00:00:00
abstract：:In contrast to the limited use of functional magnetic resonance imaging (fMRI) in clinical diagnostics, it is currently a mainstay of neuroimaging in clinical and basic brain research. However, its non-invasive use in combination with its high temporal and spatial resolution would make fMRI a perfect diagnostic tool. ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2012.02.082
更新日期：2012-05-15 00:00:00
abstract：:Golgi-impregnated neurons of the human or animal central nervous system were studied with a confocal laser scanning microscope (CLSM). The scanning properties (optical sectioning of the specimen) offered by the CLSM and the capacity of metal granules to reflect the laser beam allow a three-dimensional reconstruction o...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1006/nimg.1993.1002
更新日期：1993-09-01 00:00:00
abstract：:Functional neuroimaging research in humans has identified a number of brain areas that are activated by the delivery of primary and secondary reinforcers. The present study investigated how activity in these reward-sensitive regions is modulated by the context in which rewards and punishments are experienced. Fourteen...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：10.1016/j.neuroimage.2004.12.043
更新日期：2005-05-01 00:00:00
abstract：:Longitudinal brain atlases play an important role in the study of human brain development and cognition. Existing atlases are mainly based on anatomical features derived from T1-and T2-weighted MRI. A 4D developmental quantitative susceptibility mapping (QSM) atlas may facilitate the estimation of age-related iron cha...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2018.01.008
更新日期：2018-05-01 00:00:00
abstract：:Unilateral sensory stimulation reliably elicits contralateral somatotopic activation of primary (SI) and secondary (SII) somatosensory cortex. There is an ongoing debate about the occurrence and nature of concomitant ipsilateral SI and SII activation. Here we used functional magnetic resonance imaging (fMRI) in health...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2007.05.038
更新日期：2007-09-01 00:00:00
