Abstract：
:In infants, the fontanels and sutures as well as conductivity of the skull influence the volume currents accompanying primary currents generated by active neurons and thus the associated electroencephalography (EEG) and magnetoencephalography (MEG) signals. We used a finite element method (FEM) to construct a realistic model of the head of an infant based on MRI images. Using this model, we investigated the effects of the fontanels, sutures and skull conductivity on forward and inverse EEG and MEG source analysis. Simulation results show that MEG is better suited than EEG to study early brain development because it is much less sensitive than EEG to distortions of the volume current caused by the fontanels and sutures and to inaccurate estimates of skull conductivity. Best results will be achieved when MEG and EEG are used in combination.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Lew S,Sliva DD,Choe MS,Grant PE,Okada Y,Wolters CH,Hämäläinen MSdoi
10.1016/j.neuroimage.2013.03.017subject
Has Abstractpub_date
2013-08-01 00:00:00pages
282-93eissn
1053-8119issn
1095-9572pii
S1053-8119(13)00259-0journal_volume
76pub_type
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