Abstract：
:Examining the brain at rest is a powerful approach used to understand the intrinsic properties of typical and disordered human brain function, yet task-free paradigms are associated with greater head motion, particularly in young and/or clinical populations such as autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). Inscapes, a non-social and non-verbal movie paradigm, has been introduced to increase attention, thus mitigating head motion, while reducing the task-induced activations found during typical movie watching. Inscapes has not yet been validated for use in magnetoencephalography (MEG), and it has yet to be shown whether its effects are stable in clinical populations. Across typically developing (N = 32) children and adolescents and those with ASD (N = 46) and ADHD (N = 42), we demonstrate that head motion is reduced during Inscapes. Due to the task state evoked by movie paradigms, we also expectedly observed concomitant modulations in local neural activity (oscillatory power) and functional connectivity (phase and envelope coupling) in intrinsic resting-state networks and across the frequency spectra compared to a fixation cross resting-state. Increases in local activity were accompanied by decreases in low-frequency connectivity within and between resting-state networks, primarily the visual network, suggesting that task-state evoked by Inscapes moderates ongoing and spontaneous cortical inhibition that forms the idling intrinsic networks found during a fixation cross resting-state. Importantly, these effects were similar in ASD and ADHD, making Inscapes a well-suited advancement for investigations of resting brain function in young and clinical populations.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Vandewouw MM,Dunkley BT,Lerch JP,Anagnostou E,Taylor MJdoi
10.1016/j.neuroimage.2020.117524subject
Has Abstractpub_date
2021-01-15 00:00:00pages
117524eissn
1053-8119issn
1095-9572pii
S1053-8119(20)31009-0journal_volume
225pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract：:Among male patients affected by Kallmann syndrome, a genetically determined disease due to defective neural migration leading to hypogonadropic hypogonadism and hypo/anosmia, about 40% present the peculiar phenomenon of mirror movements, i.e. involuntary movements mirroring contralateral voluntary hand movements. Seve...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.09.067
更新日期：2015-01-01 00:00:00
abstract：:Conflicting theories identify creativity either with frontal-lobe mediated (Type-2) executive control processes or (Type-1) associative processes that are disinhibited when executive control is relaxed. Musical (jazz) improvisation is an ecologically valid test-case to distinguish between these views because relativel...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.116632
更新日期：2020-06-01 00:00:00
abstract：:Smith et al. report a large study of the accuracy of 38 search procedures for recovering effective connections in simulations of DCM models under 28 different conditions. Their results are disappointing: no method reliably finds and directs connections without large false negatives, large false positives, or both. Usi...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.06.068
更新日期：2011-10-01 00:00:00
abstract：:Positive affect elicited in a mother toward her newborn infant may be one of the most powerful and evolutionarily preserved forms of positive affect in the emotional landscape of human behavior. This study examined the neurobiology of this form of positive emotion and in so doing, sought to overcome the difficulty of ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2003.10.005
更新日期：2004-02-01 00:00:00
abstract：:Caffeine is the most widely used stimulant in the world. The stimulant effects of caffeine are mediated through its antagonistic properties on neuronal adenosine receptors. In addition, caffeine blocks neurovascular adenosine receptors and decreases cerebral perfusion. Although the effects of caffeine on blood oxygena...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2002-10-01 00:00:00
abstract：:The neural mechanisms underlying conscious visual perception have been extensively investigated using bistable perception paradigms. Previous functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation (TMS) studies suggest that the right anterior superior parietal (r-aSPL) and the right posteri...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.12.018
更新日期：2015-02-15 00:00:00
abstract：:Using conventional MRI procedures, nuclear magnetic resonance (NMR) of brain water proton (1H) T2 relaxation times and EEG coherence were obtained from two independent groups of closed head injured (CHI) patients and a group of normal control subjects. Statistically significant intercorrelations were observed between ...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：10.1006/nimg.1998.0365
更新日期：1998-11-01 00:00:00
abstract：:Diseases involving the medial temporal lobes (MTL) such as Alzheimer's disease and mesial temporal sclerosis pose an ongoing diagnostic challenge because of the difficulty in identifying conclusive imaging features, particularly in pre-clinical states. Abnormal neuronal connectivity may be present in the circuitry of ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2012.05.065
更新日期：2012-09-01 00:00:00
abstract：:Empathy may allow interindividual sharing not only of emotions (e.g., joy, sadness, disgust) but also of sensations (e.g., touch, itching, pain). Although empathy for pain may rely upon both sensory and affective components of the pain experience, neuroimaging studies indicate that only the affective component of the ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.03.010
更新日期：2006-08-01 00:00:00
abstract：:In brain-imaging research, we are often interested in making quantitative claims about effects across subjects. Given that most imaging data consist of tens to thousands of spatially correlated time series, inter-subject comparisons are typically accomplished with simple combinations of inter-subject data, for example...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2007.07.064
更新日期：2008-02-01 00:00:00
abstract：:Picture-plane inversion dramatically impairs face recognition. Behavioral and event-related potential (ERP) studies suggest that this effect takes place during perceptual encoding of the face stimulus. However, the relationship between early electrophysiological responses to upright and inverted faces and the behavior...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2007.04.016
更新日期：2007-07-01 00:00:00
abstract：:This study introduces a direct method of assessing cerebral lateralization for language based on fMRI activation. The method, derived from a voxel-based morphometry study by C. H. Salmond et al. (2000, Hum. Brain Mapping 11, 223-232), bases lateralization on the direct statistical comparison of the magnitude of task-i...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1006/nimg.2002.1327
更新日期：2002-12-01 00:00:00
abstract：OBJECTIVE:The dopamine D2/3 receptor subtypes (DRD2/3) are the most widely studied neurotransmitter biomarker in research on obesity, but results to date have been inconsistent, have typically involved small samples, and have rarely accounted for subjects' ages despite the large impact of age on DRD2/3 levels. We aimed...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2016.05.044
更新日期：2016-09-01 00:00:00
abstract：:The impairment of axonal transport by overexpression or hyperphosphorylation of tau is well documented for in vitro conditions; however, only a few studies on this phenomenon have been conducted in vivo, using invasive procedures, and with contradictory results. Here we used the non-invasive, Manganese-Enhanced Magnet...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2012.08.065
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:Multichannel Transcranial Magnetic Stimulation (mTMS) arrays enable multiple sites to be stimulated simultaneously or sequentially under electronic control without moving the system's stimulation coils. Here, we build and characterize the performance of a novel modular 3-axis TMS coil that can be utilized as a ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.117355
更新日期：2021-01-01 00:00:00
abstract：:This paper presents a pair of studies designed to empirically explore the severity of potential artifacts associated with overt verbal responding during fMRI scanning and to examine several different solutions to these artifacts. In Study One, we compared susceptibility artifacts, signal-to-noise ratios, and activatio...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1006/nimg.1999.0500
更新日期：1999-12-01 00:00:00
abstract：:Functional near-infrared spectroscopy (fNIRS) is a non-invasive brain imaging method that uses light to record regional changes in cerebral blood flow in the cortex during activation. fNIRS uses portable wearable sensors to allow measurements of brain activation during tasking. In this study, fNIRS was used to investi...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.02.010
更新日期：2013-07-01 00:00:00
abstract：:The Developing Human Connectome Project (dHCP) seeks to create the first 4-dimensional connectome of early life. Understanding this connectome in detail may provide insights into normal as well as abnormal patterns of brain development. Following established best practices adopted by the WU-MINN Human Connectome Proje...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2018.01.054
更新日期：2018-06-01 00:00:00
abstract：:Over the last two decades, numerous human MRI studies of neuroplasticity have shown compelling evidence for extensive and rapid experience-induced brain plasticity in vivo. To date, most of these studies have consisted of simply detecting a difference in structural or functional images with little concern for their la...
journal_title：NeuroImage
pub_type： 杂志文章,评审
doi：10.1016/j.neuroimage.2015.08.047
更新日期：2016-05-01 00:00:00
abstract：:The amygdala (AMG) has been repeatedly implicated in the processing of threatening and negatively valenced stimuli and multiple fMRI paradigms have reported personality, genetic, and psychopathological associations with individual differences in AMG activation in these paradigms. Yet the interchangeability of activati...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2016.11.038
更新日期：2017-02-01 00:00:00
abstract：:The dual-process theory of reasoning explained the belief-bias effect, the tendency for human reasoning to be erroneously biased when logical conclusions are incongruent with belief about the world, by proposing a belief-based fast heuristic system and a logic-based slow analytic system. Although the claims were suppo...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2010.01.026
更新日期：2010-04-15 00:00:00
abstract：:Processing speed is an important construct in understanding cognition. This study was aimed to control task specificity for understanding the neural mechanisms underlying cognitive processing speed. Forty young adult subjects performed attention tasks of two modalities (auditory and visual) and two levels of task rule...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.117556
更新日期：2021-02-01 00:00:00
abstract：:Many studies have investigated the temporal properties of BOLD signal responses to task performance in regions of interest, often noting significant departures from the conventionally modelled response shape, and significant variation between regions. However, these investigations are rarely extended across the whole ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.09.006
更新日期：2007-01-01 00:00:00
abstract：:Detecting local differences between groups of connectomes is a great challenge in neuroimaging, because the large number of tests that have to be performed and the impact on multiplicity correction. Any available information should be exploited to increase the power of detecting true between-group effects. We present ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.11.059
更新日期：2015-03-01 00:00:00
abstract：:Anticipatory anxiety is a complex combination of a future-oriented cognitive state, negative affect, and autonomic arousal. A dual-task paradigm of anticipation of electric shocks and a motor-learning task was used to examine the changes in neural patterns of activation associated with modulation of the cognitive stat...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：10.1006/nimg.1999.0407
更新日期：1999-06-01 00:00:00
abstract：:Interpretation of the blood oxygen level dependent (BOLD) response measured using functional magnetic resonance imaging (fMRI) requires an understanding of the underlying neuronal activity. Here we report on a study using both magnetoencephalography (MEG) and BOLD fMRI, to measure the brain's functional response to el...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.10.037
更新日期：2012-02-01 00:00:00
abstract：:Human contrast discrimination performance is limited by transduction nonlinearities and variability of the neural representation (noise). Whereas the nonlinearities have been well-characterised, there is less agreement about the specifics of internal noise. Psychophysical models assume that it impacts late in sensory ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2019.02.049
更新日期：2019-05-01 00:00:00
abstract：:Gamma oscillations contribute significantly to the manner in which neural activity is bound into functional assemblies. The mechanisms that underlie the human gamma response, however, are poorly understood. Previous computational models of gamma rely heavily on the results of invasive recordings in animals, and it is ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2015.02.062
更新日期：2015-05-15 00:00:00
abstract：:We have prepared an atlas of the human cerebellum using high-resolution magnetic resonance-derived images warped into the proportional stereotaxic space of Talairach and Tournoux. Software that permits simultaneous visualization of the three cardinal planes facilitated the identification of the cerebellar fissures and...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1006/nimg.1999.0459
更新日期：1999-09-01 00:00:00
abstract：:In this review, we discuss recent work by the ENIGMA Consortium (http://enigma.ini.usc.edu) - a global alliance of over 500 scientists spread across 200 institutions in 35 countries collectively analyzing brain imaging, clinical, and genetic data. Initially formed to detect genetic influences on brain measures, ENIGMA...
journal_title：NeuroImage
pub_type： 杂志文章,评审
doi：10.1016/j.neuroimage.2015.11.057
更新日期：2017-01-15 00:00:00
