The expanding genetic toolbox of the wasp Nasonia vitripennis and its relatives.

Abstract:

:The parasitoid wasp Nasonia represents a genus of four species that is emerging as a powerful genetic model system that has made and will continue to make important contributions to our understanding of evolutionary biology, development, ecology, and behavior. Particularly powerful are the haplodiploid genetics of the system, which allow some of the advantages of microbial genetics to be applied to a complex multicellular eukaryote. In addition, fertile, viable hybrids can be made among the four species in the genus. This makes Nasonia exceptionally well suited for evolutionary genetics approaches, especially when combined with its haploid genetics and tractability in the laboratory. These features are complemented by an expanding array of genomic, transcriptomic, and functional resources, the application of which has already made Nasonia an important model system in such emerging fields as evolutionary developmental biology and microbiomics. This article describes the genetic and genomic advantages of Nasonia wasps and the resources available for their genetic analysis.

journal_name

Genetics

journal_title

Genetics

authors

Lynch JA

doi

10.1534/genetics.112.147512

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

897-904

issue

4

eissn

0016-6731

issn

1943-2631

pii

199/4/897

journal_volume

199

pub_type

杂志文章,评审

相关文献

GENETICS文献大全
  • Unusual pattern of nucleotide sequence variation at the OS-E and OS-F genomic regions of Drosophila simulans.

    abstract::Nucleotide variation at the genomic region encompassing the odorant-binding protein genes OS-E and OS-F (OS region) was surveyed in two populations of Drosophila simulans, one from Europe and the other from Africa. We found that the European population shows an atypical and large haplotype structure, which extends thr...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.106.068015

    authors: Sánchez-Gracia A,Rozas J

    更新日期:2007-04-01 00:00:00

  • Simultaneous Modeling of Disease Status and Clinical Phenotypes To Increase Power in Genome-Wide Association Studies.

    abstract::Genome-wide association studies have identified thousands of variants implicated in dozens of complex diseases. Most studies collect individuals with and without disease and search for variants with different frequencies between the groups. For many of these studies, additional disease traits are also collected. Joint...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.116.198473

    authors: Bilow M,Crespo F,Pan Z,Eskin E,Eyheramendy S

    更新日期:2017-03-01 00:00:00

  • Proteasome mutants, pre4-2 and ump1-2, suppress the essential function but not the mitochondrial RNase P function of the Saccharomyces cerevisiae gene RPM2.

    abstract::The Saccharomyces cerevisiae nuclear gene RPM2 encodes a component of the mitochondrial tRNA-processing enzyme RNase P. Cells grown on fermentable carbon sources do not require mitochondrial tRNA processing activity, but still require RPM2, indicating an additional function for the Rpm2 protein. RPM2-null cells arrest...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Lutz MS,Ellis SR,Martin NC

    更新日期:2000-03-01 00:00:00

  • Different Frequency in the Recovery of Crossover Products from Male and Female Gametes of Plants Hypoploid for B-a Translocations in Maize.

    abstract::The percentage of crossovers is consistently higher in plants hypoploid for six B-A translocations when crossed as males than when crossed as females; in most instances, this excess of male crossing over exceeds that found in control crosses (involving normal chromosomes). Thus, there seems to be something about the h...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Robertson DS

    更新日期:1984-05-01 00:00:00

  • Major regulatory genes in maize contribute to standing variation in teosinte (Zea mays ssp. parviglumis).

    abstract::In plants, many major regulatory genes that control plant growth and development have been identified and characterized. Despite a detailed knowledge of the function of these genes little is known about how they contribute to the natural variation for complex traits. To determine whether major regulatory genes of maiz...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.080424

    authors: Weber A,Clark RM,Vaughn L,Sánchez-Gonzalez Jde J,Yu J,Yandell BS,Bradbury P,Doebley J

    更新日期:2007-12-01 00:00:00

  • Complexities of chromosome landing in a highly duplicated genome: toward map-based cloning of a gene controlling blackleg resistance in Brassica napus.

    abstract::The LmR1 locus, which controls seedling resistance to the blackleg fungus Leptosphaeria maculans in the Brassica napus cultivar Shiralee, was positioned on linkage group N7. Fine genetic mapping in a population of 2500 backcross lines identified three molecular markers that cosegregated with LmR1. Additional linkage m...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.105.049098

    authors: Mayerhofer R,Wilde K,Mayerhofer M,Lydiate D,Bansal VK,Good AG,Parkin IA

    更新日期:2005-12-01 00:00:00

  • Maintenance of Heterochromatin by the Large Subunit of the CAF-1 Replication-Coupled Histone Chaperone Requires Its Interaction with HP1a Through a Conserved Motif.

    abstract::In eukaryotic cells, the organization of genomic DNA into chromatin regulates many biological processes, from the control of gene expression to the regulation of chromosome segregation. The proper maintenance of this structure upon cell division is therefore of prime importance during development for the maintenance o...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.116.190785

    authors: Roelens B,Clémot M,Leroux-Coyau M,Klapholz B,Dostatni N

    更新日期:2017-01-01 00:00:00

  • Preferential Occurrence of Nonsister Spores in Two-Spored Asci of SACCHAROMYCES CEREVISIAE: Evidence for Regulation of Spore-Wall Formation by the Spindle Pole Body.

    abstract::Yeast cells subjected to a reversible thermal arrest of meiosis yielded progressively fewer spores per ascus as the arrest was extended. Dissection of two-spored asci by a newly developed method that prevents selection of false asci revealed that the spores were not a random sample of the haploid meiotic products. Mos...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Davidow LS,Goetsch L,Byers B

    更新日期:1980-03-01 00:00:00

  • fumble encodes a pantothenate kinase homolog required for proper mitosis and meiosis in Drosophila melanogaster.

    abstract::A number of fundamental processes comprise the cell division cycle, including spindle formation, chromosome segregation, and cytokinesis. Our current understanding of these processes has benefited from the isolation and analysis of mutants, with the meiotic divisions in the male germline of Drosophila being particular...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Afshar K,Gönczy P,DiNardo S,Wasserman SA

    更新日期:2001-03-01 00:00:00

  • Partial selfing and linkage: the effect of a heterotic locus on a neutral locus.

    abstract::Equilibria are determined for the two-locus model in a partially selfing population when one locus is neutral and the other locus is heterotic. At an equilibrium point, the frequency of heterozygotes at the neutral locus is greater than that expected from one-locus theory, even if the heterotic locus is on a different...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Strobeck C

    更新日期:1979-05-01 00:00:00

  • Integrity and function of the Saccharomyces cerevisiae spindle pole body depends on connections between the membrane proteins Ndc1, Rtn1, and Yop1.

    abstract::The nuclear envelope in Saccharomyces cerevisiae harbors two essential macromolecular protein assemblies: the nuclear pore complexes (NPCs) that enable nucleocytoplasmic transport, and the spindle pole bodies (SPBs) that mediate chromosome segregation. Previously, based on metazoan and budding yeast studies, we report...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.112.141465

    authors: Casey AK,Dawson TR,Chen J,Friederichs JM,Jaspersen SL,Wente SR

    更新日期:2012-10-01 00:00:00

  • The role of Gcr1p in the transcriptional activation of glycolytic genes in yeast Saccharomyces cerevisiae.

    abstract::To study the interdependence of Gcr1p and Rap1p, we prepared a series of synthetic regulatory sequences that contained various numbers and combinations of CT-boxes (Gcr1p-binding sites) and RPG-boxes (Rap1p-binding sites). The ability of the synthetic oligonucleotides to function as regulatory sequences was tested usi...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Uemura H,Koshio M,Inoue Y,Lopez MC,Baker HV

    更新日期:1997-10-01 00:00:00

  • The PBN1 gene of Saccharomyces cerevisiae: an essential gene that is required for the post-translational processing of the protease B precursor.

    abstract::The vacuolar hydrolase protease B in Saccharomyces cerevisiae is synthesized as an inactive precursor (Prb1p). The precursor undergoes post-translational modifications while transiting the secretory pathway. In addition to N- and O-linked glycosylations, four proteolytic cleavages occur during the maturation of Prb1p....

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Naik RR,Jones EW

    更新日期:1998-07-01 00:00:00

  • An exact sampling formula for the Wright-Fisher model and a solution to a conjecture about the finite-island model.

    abstract::An exact sampling formula for a Wright-Fisher population of fixed size N under the infinitely many neutral alleles model is deduced. This extends the Ewens formula for the configuration of a random sample to the case where the sample is drawn from a population of small size, that is, without the usual large-N and smal...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.077644

    authors: Lessard S

    更新日期:2007-10-01 00:00:00

  • Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae.

    abstract::Chromatin organization and structure are crucial for transcriptional regulation, DNA replication, and damage repair. Although initially characterized in remodeling cell wall glucans, the β-1,3-glucanosyltransferase Gas1 was recently discovered to regulate transcriptional silencing in a manner separable from its activi...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.113.158824

    authors: Eustice M,Pillus L

    更新日期:2014-04-01 00:00:00

  • Virility Deficiency and the Sex-Ratio Trait in DROSOPHILA PSEUDOOBSCURA. I. Sperm Displacement and Sexual Selection.

    abstract::The Sex-Ratio (SR) phenomenon is associated with the X chromosome of many species of Drosophila. Males carrying SR transmit predominantly sperm bearing the X chromosome. SR, therefore, has a very significant advantage in segregation. This paper provides an experimental analysis of the role of virility selection in pre...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Wu CI

    更新日期:1983-11-01 00:00:00

  • Genome analysis of Chlamydomonas reinhardtii reveals the existence of multiple, compartmentalized iron-sulfur protein assembly machineries of different evolutionary origins.

    abstract::The unicellular green alga Chlamydomonas reinhardtii is used extensively as a model to study eukaryotic photosynthesis, flagellar functions, and more recently the production of hydrogen as biofuel. Two of these processes, photosynthesis and hydrogen production, are highly dependent on iron-sulfur (Fe-S) enzymes. To un...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.086033

    authors: Godman J,Balk J

    更新日期:2008-05-01 00:00:00

  • Genetic analysis of X-chromosome dosage compensation in Caenorhabditis elegans.

    abstract::We have shown that the phenotypes resulting from hypomorphic mutations (causing reduction but not complete loss of function) in two X-linked genes can be used as a genetic assay for X-chromosome dosage compensation in Caenorhabditis elegans between males (XO) and hermaphrodites (XX). In addition we show that recessive...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Meneely PM,Wood WB

    更新日期:1987-09-01 00:00:00

  • Estimation of the amount of DNA polymorphism when the neutral mutation rate varies among sites.

    abstract::Knowing the amount of DNA polymorphism is essential to understand the mechanism of maintaining DNA polymorphism in a natural population. The amount of DNA polymorphism can be measured by the average number of nucleotide differences per site (pi), the proportion of segregating (polymorphic) site (s) and the minimum num...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Misawa K,Tajima F

    更新日期:1997-12-01 00:00:00

  • Multiple rescue factors within a Wolbachia strain.

    abstract::Wolbachia-induced cytoplasmic incompatibility (CI) is expressed when infected males are crossed with either uninfected females or females infected with Wolbachia of different CI specificity. In diploid insects, CI results in embryonic mortality, apparently due to the the loss of the paternal set of chromosomes, usuall...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.086488

    authors: Zabalou S,Apostolaki A,Pattas S,Veneti Z,Paraskevopoulos C,Livadaras I,Markakis G,Brissac T,Merçot H,Bourtzis K

    更新日期:2008-04-01 00:00:00

  • Molecular structure and transformation of the glucose dehydrogenase gene in Drosophila melanogaster.

    abstract::We have precisely mapped and sequenced the three 5' exons of the Drosophila melanogaster Gld gene and have identified the start sites for transcription and translation. The first exon is composed of 335 nucleotides and does not contain any putative translation start codons. The second exon is separated from the first ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Whetten R,Organ E,Krasney P,Cox-Foster D,Cavener D

    更新日期:1988-10-01 00:00:00

  • Meiotic alterations in CAG repeat tracts.

    abstract::We have investigated meiotic changes in CAG repeat tracts embedded in a yeast chromosome. Repeat tracts undergo either conversion events between homologs or expansion and contraction events that appear to be confined to a single chromatid. We did not find evidence for conversion of tract interruptions or excess exchan...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Schweitzer JK,Reinke SS,Livingston DM

    更新日期:2001-12-01 00:00:00

  • Selection and identification of a spontaneous alien chromosome translocation in wheat.

    abstract::A wheat (Triticum aestivum L. emend Thell) disomic addition line (2n = 6x = 44), SH1-152-2, with a pair of Elytrigia pontica (Podp.) Holub 2n = 10x = 70 [syn. Agropyron elongatum (Host) P.B.] chromosomes controlling blue aleurone color was crossed with a short-statured spring wheat ;Sonora 64' (T. aestivum). Isoline p...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Jan CC,Dvorák J,Qualset CO,Soliman KM

    更新日期:1981-06-01 00:00:00

  • An unusual Y chromosome of Drosophila simulans carrying amplified rDNA spacer without rRNA genes.

    abstract::The X and Y chromosomes of Drosophila melanogaster each contain a cluster of several hundred ribosomal RNA genes (rDNA). A nontranscribed spacer region separates adjacent rRNA genes and contains tandem copies of 240 bp repeats that include the initiation site for RNA polymerase I transcription. We show here that Droso...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Lohe AR,Roberts PA

    更新日期:1990-06-01 00:00:00

  • Multilocus evolution in fire ants: effects of selection, gene flow and recombination.

    abstract::The reproductive success of individual fire ant queens (Solenopsis invicta) previously has been shown to be strongly influenced by their genotype at a single enzyme-encoding gene, designated Pgm-3. This paper presents evidence that a second, tightly linked gene, designated Gp-9, is under similarly strong selection in ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Ross KG

    更新日期:1997-04-01 00:00:00

  • Recovery of heritable, transposon-induced, mutant alleles of the rf 2 nuclear restorer of T-cytoplasm maize.

    abstract::T (Texas) cytoplasm is associated with a mitochondrial disruption that is phenotypically expressed during microsporogenesis resulting in male sterility. Restoration of pollen fertility in T-cytoplasm maize is controlled by dominant alleles at two unlinked, complementary, nuclear-encoded genes, rf1 and rf2. As a first ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Schnable PS,Wise RP

    更新日期:1994-03-01 00:00:00

  • Analysis of Nondisjunction Induced by the R-X1 Deficiency during Microsporogenesis in Zea Mays L.

    abstract::The r-X1 deficiency in maize induces nondisjunction at the second mitotic division during embryo sac formation. However, it was not known if this deficiency also induces nondisjunction during the microspore divisions. Microsporogenesis in plants lacking or containing this deficiency was compared using two approaches. ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Zhao ZY,Weber DF

    更新日期:1988-08-01 00:00:00

  • Flanking duplications and deletions associated with P-induced male recombination in Drosophila.

    abstract::We studied P element-induced recombination in germline mitotic cells by examining the structure of the recombinant chromosomes. We found that most recombinants retain a mobile P element at the site of the recombination, usually with either a deletion or a duplication immediately adjacent to the P end at which the cros...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Preston CR,Sved JA,Engels WR

    更新日期:1996-12-01 00:00:00

  • Variance of neutral genetic variances within and between populations for a quantitative character.

    abstract::The variances of genetic variances within and between finite populations were systematically studied using a general multiple allele model with mutation in terms of identity by descent measures. We partitioned the genetic variances into components corresponding to genetic variances and covariances within and between l...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Zeng ZB,Cockerham CC

    更新日期:1991-10-01 00:00:00

  • swi6, a gene required for mating-type switching, prohibits meiotic recombination in the mat2-mat3 "cold spot" of fission yeast.

    abstract::Mitotic interconversion of the mating-type locus (mat1) of the fission yeast Schizosaccharomyces pombe is initiated by a double-strand break at mat1. The mat2 and mat3 loci act as nonrandom donors of genetic information for mat1 switching such that switches occur primarily (or only) to the opposite mat1 allele. Locati...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Klar AJ,Bonaduce MJ

    更新日期:1991-12-01 00:00:00