N-acetylaspartate reduction in the medial prefrontal cortex following 8 weeks of risperidone treatment in first-episode drug-naïve schizophrenia patients.

abstract：:El Niño-Southern Oscillation (ENSO), which is one of the main drivers of Earth's inter-annual climate variability, often causes a wide range of climate anomalies, and the advance prediction of ENSO is always an important and challenging scientific issue. Since a unified and complete ENSO theory has yet to be establish...

journal_title：Scientific reports

authors： Yan J,Mu L,Wang L,Ranjan R,Zomaya AY

更新日期：2020-05-15 00:00:00

abstract：:High frequency repetitive transcranial magnetic stimulation (HF-rTMS) over the left dorsolateral prefrontal cortex (L-DLPFC) is a widely applied treatment protocol for chronic smoking and major depressive disorder. However, no previous study has measured the effects of rTMS on both nicotine consumption and anxiety/dep...

journal_title：Scientific reports

authors： Abdelrahman AA,Noaman M,Fawzy M,Moheb A,Karim AA,Khedr EM

更新日期：2021-01-15 00:00:00

abstract：:Neural crest cells (NCC) are stem cells that generate different lineages, including neuroendocrine, melanocytic, cartilage, and bone. The differentiation potential of NCC varies according to the level from which cells emerge along the neural tube. For example, only anterior "cranial" NCC form craniofacial bone, wherea...

journal_title：Scientific reports

authors： Huang M,Miller ML,McHenry LK,Zheng T,Zhen Q,Ilkhanizadeh S,Conklin BR,Bronner ME,Weiss WA

更新日期：2016-01-27 00:00:00

abstract：:Fatty acid oxidation and subsequent ketogenesis is one of the major mechanisms to maintain hepatic lipid homeostasis under fasting conditions. Fasting hormone glucagon has been shown to stimulate ketone body production through activation of PPARα; however, the signal pathway linking glucagon to PPARα is largely undisc...

journal_title：Scientific reports

authors： Zhang ZN,Gong L,Lv S,Li J,Tai X,Cao W,Peng B,Qu S,Li W,Zhang C,Luan B

更新日期：2016-03-17 00:00:00

abstract：:Most Group I Clostridium botulinum strains harbor botulinum neurotoxin (bont) genes on their chromosome, while some carry these genes (including bont/a, bont/b, and bont/f) on large plasmids. Prior work in our laboratory demonstrated that Group I BoNT plasmids were mobilized to C. botulinum recipient strains containin...

journal_title：Scientific reports

authors： Nawrocki EM,Bradshaw M,Johnson EA

更新日期：2018-02-15 00:00:00

abstract：:Sigma-1 and sigma-2 receptors are emerging therapeutic targets. We have identified that simple ammonium salts bind to these receptors and are effective in vivo. Radioligand binding assays were used to obtain structure-activity relationships of these salts. MTS assays were performed to determine their effect on growth ...

journal_title：Scientific reports

authors： Brimson JM,Akula KK,Abbas H,Ferry DR,Kulkarni SK,Russell ST,Tisdale MJ,Tencomnao T,Safrany ST

更新日期：2020-06-08 00:00:00

abstract：:Are you walking at me? Biological movement and the encoding of its motion and orientation. A person's motion conveys a wealth of information that ranges from the complex, such as intention or emotional state, to the simple, such as direction of locomotion. How we recognise and recover people's motion is addressed by m...

journal_title：Scientific reports

authors： Benton CP,Thirkettle M,Scott-Samuel NE

更新日期：2016-02-29 00:00:00

abstract：:Circadian disruption resulting from exposure to irregular light-dark patterns and sleep deprivation has been associated with beta amyloid peptide (Aβ) aggregation, which is a major event in Alzheimer's disease (AD) pathology. We exposed 5XFAD mice and littermate controls to dim-light vs. bright-light photophases to in...

journal_title：Scientific reports

authors： Nagare R,Possidente B,Lagalwar S,Figueiro MG

更新日期：2020-07-10 00:00:00

abstract：:Core-shell nanoparticles often exhibit improved catalytic properties due to the lattice strain created in these core-shell particles. Herein, we demonstrate the synthesis of core-shell Au@Pd nanoparticles from their core-shell Au@Ag/Pd parents. This strategy begins with the preparation of core-shell Au@Ag nanoparticle...

journal_title：Scientific reports

authors： Chen D,Li C,Liu H,Ye F,Yang J

更新日期：2015-07-06 00:00:00

abstract：:Asymmetric transmission (AT) devices are fundamental elements for optical computing and information processing. We here propose an AT device consisting of a pair of coupled complementary subwavelength gratings. Different from previous works, asymmetric dielectric environment is employed for unidirectional excitation o...

journal_title：Scientific reports

authors： Li S,Huang LR,Ling YH,Liu WB,Ba CF,Li HH

更新日期：2019-11-19 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, which are the component cells of intrahepatic bile ducts. However, as patients with viral hepatitis often develop IHCC, it has been suggested that transformed hepatocytes may ...

journal_title：Scientific reports

authors： Saito Y,Nakaoka T,Muramatsu T,Ojima H,Sukeda A,Sugiyama Y,Uchida R,Furukawa R,Kitahara A,Sato T,Kanai Y,Saito H

更新日期：2018-02-12 00:00:00

abstract：:Local communities are assembled from larger-scale species pools via dispersal, environmental filtering, biotic interactions, and local stochastic demographic processes. The relative importance, scaling and interplay of these assembly processes can be elucidated by comparing local communities to variously circumscribed...

journal_title：Scientific reports

authors： Feng G,Mi X,Eiserhardt WL,Jin G,Sang W,Lu Z,Wang X,Li X,Li B,Sun I,Ma K,Svenning JC

更新日期：2015-03-23 00:00:00

abstract：:This work provides new insights into the dynamics of silica nanoparticle-based removal of organic fluids (here oil) from naturally occurring porous media. We have used 4D (time-resolved 3D) imaging at pore-scale using X-ray computed micro-tomography (μCT) technique. The captured 3D tomographic time-series data reveal ...

journal_title：Scientific reports

authors： Pak T,Archilha NL,Mantovani IF,Moreira AC,Butler IB

更新日期：2018-07-24 00:00:00

abstract：:Male moths use species-specific sex pheromones to identify and orientate toward conspecific females. Odorant receptors (ORs) for sex pheromone substances have been identified as sex pheromone receptors in various moth species. However, direct in vivo evidence linking the functional role of these ORs with behavioural r...

journal_title：Scientific reports

authors： Sakurai T,Mitsuno H,Mikami A,Uchino K,Tabuchi M,Zhang F,Sezutsu H,Kanzaki R

更新日期：2015-06-05 00:00:00

abstract：:Abnormal dopaminergic transmission has been implicated as a risk determinant of HIV-1-associated neurocognitive disorders. HIV-1 Tat protein increases synaptic dopamine (DA) levels by directly inhibiting DA transporter (DAT) activity, ultimately leading to dopaminergic neuron damage. Through integrated computational m...

journal_title：Scientific reports

authors： Quizon PM,Sun WL,Yuan Y,Midde NM,Zhan CG,Zhu J

更新日期：2016-12-14 00:00:00

abstract：:Future climate change has the potential to alter the distribution and prevalence of plant pathogens, which may have significant implications for both agricultural crops and natural plant communities. However, there are few long-term datasets against which modelled predictions of pathogen responses to climate change ca...

journal_title：Scientific reports

authors： Wood JR,Díaz FP,Latorre C,Wilmshurst JM,Burge OR,Gutiérrez RA

更新日期：2018-11-21 00:00:00

abstract：:A detailed characterisation of the molecular determinants of membrane binding by α-synuclein (αS), a 140-residue protein whose aggregation is associated with Parkinson's disease, is of fundamental significance to clarify the manner in which the balance between functional and dysfunctional processes are regulated for t...

journal_title：Scientific reports

authors： Fusco G,De Simone A,Arosio P,Vendruscolo M,Veglia G,Dobson CM

更新日期：2016-06-08 00:00:00

abstract：:Collagen, the dominating material in the extracellular matrix, provides the strength, elasticity and mechanical stability to the organisms. The mechanical property of collagen is mainly dominated by its surrounding environments. However, the variation and origin of the mechanics of collagen fibril under different conc...

journal_title：Scientific reports

authors： Pang X,Lin L,Tang B

更新日期：2017-04-05 00:00:00

abstract：:We report the transient memory device by means of a water soluble SSG (solid sodium with glycerine) paper. This material has a hydroscopic property hence it can be soluble in water. In terms of physical security of memory devices, prompt abrogation of a memory device which stored a large number of data is crucial when...

journal_title：Scientific reports

authors： Bae H,Lee BH,Lee D,Seol ML,Kim D,Han JW,Kim CK,Jeon SB,Ahn D,Park SJ,Park JY,Choi YK

更新日期：2016-12-05 00:00:00

abstract：:The Maxwellian near-eye displays have attracted growing interest in various applications. By using a confined pupil, a Maxwellian display presents an all-in-focus image to the viewer where the image formed on the retina is independent of the optical power of the eye. Despite being a promising technique, current Maxwel...

journal_title：Scientific reports

authors： Chang C,Cui W,Park J,Gao L

更新日期：2019-12-10 00:00:00

abstract：:Silicon nanocrystals offer huge advantages compared to other semi-conductor quantum dots as they are made from an abundant, non-toxic material and are compatible with silicon devices. Besides, among a wealth of extraordinary properties ranging from catalysis to nanomedicine, metal nanoparticles are known to increase t...

journal_title：Scientific reports

authors： Goffard J,Gérard D,Miska P,Baudrion AL,Deturche R,Plain J

更新日期：2013-01-01 00:00:00

abstract：:An initial study of processing bioresorbable polycaprolactone (PCL) through material jetting was conducted using a Fujifilm Dimatix DMP-2830 material printer. The aim of this work was to investigate a potential solvent based method of jetting polycaprolactone. Several solvents were used to prepare a PCL solvent based ...

journal_title：Scientific reports

authors： He Y,Wildman RD,Tuck CJ,Christie SD,Edmondson S

更新日期：2016-02-12 00:00:00

abstract：:The aim was to investigate the ability of self-assembling Peptide P11-4 Matrix (SAPM) to remineralize artificial initial caries lesions compared to the use of fluoride varnish. Volunteers were recruited for this randomised, cross-over in situ trial. Bovine specimens, half including orthodontic brackets, were recessed ...

journal_title：Scientific reports

authors： Jablonski-Momeni A,Korbmacher-Steiner H,Heinzel-Gutenbrunner M,Jablonski B,Jaquet W,Bottenberg P

更新日期：2019-01-22 00:00:00

abstract：:The over-expression and aggregation of α-synuclein (αSyn) are linked to the onset and pathology of Parkinson's disease. Native monomeric αSyn exists in an intrinsically disordered ensemble of interconverting conformations, which has made its therapeutic targeting by small molecules highly challenging. Nonetheless, her...

journal_title：Scientific reports

authors： Tóth G,Neumann T,Berthet A,Masliah E,Spencer B,Tao J,Jobling MF,Gardai SJ,Bertoncini CW,Cremades N,Bova M,Ballaron S,Chen XH,Mao W,Nguyen P,Tabios MC,Tambe MA,Rochet JC,Junker HD,Schwizer D,Sekul R,Ott I,Ander

更新日期：2019-11-18 00:00:00

abstract：:Mountain ecosystems serve as sentinels of change, and those in the Canadian Rocky Mountains have undergone a pronounced shift over the past century. We present quantitative analyses of 81 high-resolution image pairs of systematic historic surveys and repeat photographs of Canadian Rocky Mountain habitats, measuring tr...

journal_title：Scientific reports

authors： Trant A,Higgs E,Starzomski BM

更新日期：2020-06-16 00:00:00

abstract：:Recent evidence suggests that some seizures are preceded by preictal changes that start from minutes to hours before an ictal event. Nevertheless an adequate statistical evaluation in a large database of continuous multiday recordings is still missing. Here, we investigated the existence of preictal changes in long-te...

journal_title：Scientific reports

authors： Alvarado-Rojas C,Valderrama M,Fouad-Ahmed A,Feldwisch-Drentrup H,Ihle M,Teixeira CA,Sales F,Schulze-Bonhage A,Adam C,Dourado A,Charpier S,Navarro V,Le Van Quyen M

更新日期：2014-04-01 00:00:00

abstract：:Monoclonal antibodies have a variety of applications in research and medicine. Here, we report development of a new method for production of monoclonal antibodies. Our method relies on in vivo RNA transfection rather than peptide vaccination. We took advantage of RNA transcripts complexed with DOTMA and DOPE lipids to...

journal_title：Scientific reports

authors： Romani B,Kavyanifard A,Allahbakhshi E

更新日期：2017-09-07 00:00:00

abstract：:ATP depletion and succinate accumulation during ischemia lead to oxidative damage to mammalian organs upon reperfusion. In contrast, freshwater turtles survive weeks of anoxia at low temperatures without suffering from oxidative damage upon reoxygenation, but the mechanisms are unclear. To determine how turtles surviv...

journal_title：Scientific reports

authors： Bundgaard A,James AM,Gruszczyk AV,Martin J,Murphy MP,Fago A

更新日期：2019-02-26 00:00:00

abstract：:Multiple predatory insect lineages have developed a raptorial lifestyle by which they strike and hold prey using modified forelegs armed with spine-like structures and other integumentary specialisations. However, how structures enabling the raptorial function evolved in insects remains largely hypothetical or inferre...

journal_title：Scientific reports

authors： Pérez-de la Fuente R,Peñalver E

更新日期：2019-09-13 00:00:00

abstract：:Perovskite solar cells based on series of inorganic cesium lead bromide and iodide mixture, CsPbBr3-xI x , where x varies between 0, 0.1, 0.2, and 0.3 molar ratio were synthesized by two step-sequential deposition at ambient condition to design the variations of wide band gap light absorbers. A device with high overal...

journal_title：Scientific reports

authors： Ng CH,Ripolles TS,Hamada K,Teo SH,Lim HN,Bisquert J,Hayase S

更新日期：2018-02-06 00:00:00