Abstract:
:The non N-methyl-D-aspartate (NMDA) receptor antagonists dinitroquinoxaline-2,3-dione (DNQX) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), both inhibit the visually driven response of sustained ganglion cells in the cat retina in vivo. In contrast to these findings, the potent NMDA receptor antagonist 3-[+/- )-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP) has no effect. Thus, the endogenous excitatory amino acid released onto these cells on visual stimulation acts at non-NMDA receptors.
journal_name
Eur J Pharmacoljournal_title
European journal of pharmacologyauthors
Kay CD,Ikeda Hdoi
10.1016/0014-2999(89)90483-4subject
Has Abstractpub_date
1989-05-19 00:00:00pages
381-4issue
2eissn
0014-2999issn
1879-0712pii
0014-2999(89)90483-4journal_volume
164pub_type
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