Supplementation of vitamin D in pregnancy and its correlation with feto-maternal outcome.

abstract：OBJECTIVE:Non-tumour causes of hyperprolactinaemia, including prolactin-elevating drugs, must be excluded. There is a general view that such drugs are unlikely to raise serum PRL above 3000 mU/I, but the literature is confusing. We report 8 patients receiving treatment with neuroleptic drugs, whose serum PRL concentrat...

journal_title：Clinical endocrinology

authors： Pollock A,McLaren EH

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:In the present study we have performed a grey-scale quantitative analysis of thyroid echogenicity in the patients affected by Hashimoto's thyroiditis (HT), obtaining a numerical estimate of the degree of hypoechogenicity associated with the appearance of thyroid dysfunction. MATERIALS AND METHODS:The study g...

journal_title：Clinical endocrinology

authors： Mazziotti G,Sorvillo F,Iorio S,Carbone A,Romeo A,Piscopo M,Capuano S,Capuano E,Amato G,Carella C

更新日期：2003-08-01 00:00:00

abstract：:Phaeochromocytomas and paragangliomas (PPGLs) are rare tumours that arise from the adrenal medulla or extra-adrenal sympathetic or parasympathetic paraganglia. Recent advances in genetics have greatly enhanced understanding of the pathogenesis and molecular physiology of PPGL. Concomitantly, advances in molecular imag...

journal_title：Clinical endocrinology

authors： Ryder SJ,Love AJ,Duncan EL,Pattison DA

更新日期：2020-12-09 00:00:00

abstract：:High gastrin levels were found in twenty-one out of fifty-six consecutive patients (38%) with thyrotoxicosis. Following return to euthyroidism gastrin levels generally fell, but twelve patients (21%) remained hypergastrinaemic. Six of these patients (11%) had achlorhydria indicating atrophic gastritis of the antrum sp...

journal_title：Clinical endocrinology

authors： Dahlberg PA,Karlsson FA,Lundqvist G

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVE:We have evaluated the efficacy of percutaneous ethanol injection as an alternative to surgery and iodine-131 treatment in solitary autonomous thyroid adenoma. DESIGN:Percutaneous ethanol injection (0.5-2.8 ml ethanol/ml nodular tissue) was performed under sonographic guidance in 3-5 (1-2 weekly) sessions; a ...

journal_title：Clinical endocrinology

authors： Monzani F,Goletti O,Caraccio N,Del Guerra P,Ferdeghini M,Pucci E,Baschieri L

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:This study explored leptin concentrations in Prader-Willi syndrome (PWS), a genetic disorder characterized by significant obesity and presumed hypothalamic dysfunction. The potential interaction of leptin metabolism with the growth hormone (GH) axis was also studied. STUDY DESIGN:Plasma leptin concentrations...

journal_title：Clinical endocrinology

authors： Myers SE,Davis A,Whitman BY,Santiago JV,Landt M

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Research on sources of variation in adolescent's gonadal hormone levels is limited. We sought to decompose individual differences in adolescent testosterone, estradiol, and pubertal status, into genetic and environmental components. DESIGN:A sample of male and female adolescent twins from the greater Austin ...

journal_title：Clinical endocrinology

authors： Grotzinger AD,Mann FD,Patterson MW,Herzhoff K,Tackett JL,Tucker-Drob EM,Paige Harden K

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this investigation was to evaluate the effectiveness of short-term administration of recombinant biosynthetic IGF-I on patients with an hereditary inability to generate this hormone. DESIGN AND PATIENTS:Ten patients with Laron type dwarfism (LTD) (4 males, six females) aged 3 1/2 to 37 3/4 yea...

journal_title：Clinical endocrinology

authors： Laron Z,Klinger B,Jensen LT,Erster B

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:As only sparse data are available, we aimed to investigate whether needs for activated vitamin D and calcium supplements change in women with hypoparathyroidism during pregnancy and lactation and risk of pregnancy-related complications. DESIGN:Retrospective review of medical records. PATIENTS:Twelve Danish ...

journal_title：Clinical endocrinology

authors： Hartogsohn EAR,Khan AA,Kjaersulf LU,Sikjaer T,Hussain S,Rejnmark L

更新日期：2020-09-01 00:00:00

abstract：:Twenty-four hyperprolactinaemic women were treated for 6 months with the new, non-ergot, long-acting dopamine agonist, CV 205-502. The treatment resulted in normalization of PRL secretion in 17 of the 24 women at once-daily doses of 0.05 to 0.15 mg of the drug. Sixteen of these women as well as 4 of those who remained...

journal_title：Clinical endocrinology

authors： Rasmussen C,Bergh T,Wide L,Brownell J

更新日期：1988-09-01 00:00:00

abstract：:A convenient, sensitive radioimmunoassay of free thyroxine in serum dialysates is described. The method utilizes a solid phase separation system (pre-formed double antibody) and a relatively short incubation period (220 min) with a staggered addition of tracer. Blanks were low and consistent. The normal range for non-...

journal_title：Clinical endocrinology

authors： Giles AF

更新日期：1982-01-01 00:00:00

abstract：:Millions of women are treated with hormone replacement therapy (HRT) for relief of menopausal symptoms, including vasomotor flushes and sweats for which oestrogen is uniquely and highly effective. Others may continue longer-term treatment in the hope that HRT will help to prevent chronic disease. The preservation of b...

journal_title：Clinical endocrinology

authors： Armitage M,Nooney J,Evans S

更新日期：2003-08-01 00:00:00

abstract：:A 42-year-old woman had galactorrhoea and amenorrhoea. Four years previously she complained of sensory disturbance of her legs, with galt disturbance. Serum PRL level was 1408 mU/l. Magnetic resonance imaging showed a spindle-shaped mass in the spinal canal at the level of the ninth thoracic vertebra. The tumour was r...

journal_title：Clinical endocrinology

authors： Katsuren E,Ishikawa S,Honda K,Saito T

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There are currently no sensitive and specific assays for activin B that could be utilized to study human biological fluids. The aim of this project was to develop and validate a 'total' activin B ELISA for use with human biological fluids and establish concentrations of activin B in the circula...

journal_title：Clinical endocrinology

authors： Ludlow H,Phillips DJ,Myers M,McLachlan RI,de Kretser DM,Allan CA,Anderson RA,Groome NP,Hyvönen M,Duncan WC,Muttukrishna S

更新日期：2009-12-01 00:00:00

abstract：:We studied day/night (D:N) patterns of urinary sodium excretion and the 24 hour ambulatory electrocardiogram in seven normal subjects before and during the administration of T4. Thyroxine increased thyroid hormone levels within the normal range and inhibited the plasma TSH response to TRH. This was associated with a s...

journal_title：Clinical endocrinology

authors： Bell GM,Sawers JS,Forfar JC,Doig A,Toft AD

更新日期：1983-05-01 00:00:00

abstract：OBJECTIVE:To compare biochemical variables, renal function and calcium and vitamin D intakes in euparathyroid and hyperparathyroid patients with primary osteoporosis and osteopenia and describe the measures necessary to normalize serum PTH in the patients with secondary hyperparathyroidism. DESIGN AND PATIENTS:We revi...

journal_title：Clinical endocrinology

authors： Yendt ER,Kovacs KA,Jones G

更新日期：2008-12-01 00:00:00

abstract：:Thirty-three samples of follicular fluid (FF) were collected from 14 patients with the polycystic ovary (PCO) syndrome and matched for FF-volume with small follicles collected from subjects with normal ovaries. The median (range) FF concentration of insulin-like growth factor 1 (IGF1) in the group with PCO, 0.42 (0.13...

journal_title：Clinical endocrinology

authors： Eden JA,Jones J,Carter GD,Alaghband-Zadeh J

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:The aim was to study the pharmacokinetic parameters and biological activity of a single dose of human recombinant IGF-I (rhIGF-I) administered to patients following major gastrointestinal surgery. DESIGN:A double blind placebo controlled externally randomized study of 30 patients; the study commencing 24 hou...

journal_title：Clinical endocrinology

authors： Miell JP,Taylor AM,Jones J,Buchanan CR,Rennie J,Sherwood R,Leicester R,Ross RJ

更新日期：1992-12-01 00:00:00

abstract：:Twelve female patients (mean age 60 years, range 41--74) with euthyroid multinodular goitre and a flat TRH test (median delta TSH 0.9 muIU/ml, range 0--3.5) had normal prolactin responses to TRH (median data prolactin 48 ng/ml, range 6--115). The results are comparable with those in euthyroid patients receiving full s...

journal_title：Clinical endocrinology

authors： Elte JW,Wiarda KS,Frölich M,Haak A

更新日期：1978-11-01 00:00:00

abstract：OBJECTIVE:Low growth hormone (GH) secretion and hypogonadism are common in patients with Prader-Willi syndrome (PWS). In this study we present the effects of GH treatment on body composition and metabolism in adults with PWS. PATIENTS AND MEASUREMENTS:Nineteen patients with clinical PWS were recruited, 13 had PWS geno...

journal_title：Clinical endocrinology

authors： Höybye C,Hilding A,Jacobsson H,Thorén M

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:This study was designed in order to evaluate bone turnover with bone formation and resorption markers in hyperthyroidism and its possible relationship with serum cytokines interleukin 6 (IL-6) and tumour necrosis-alpha (TNF-alpha), levels of thyroid hormones and thyroid autoantibodies. DESIGN AND PATIENTS:Tw...

journal_title：Clinical endocrinology

authors： Akalin A,Colak O,Alatas O,Efe B

更新日期：2002-07-01 00:00:00

abstract：:Eleven women with secondary amenorrhoea and hyperprolactinaemia were treated with lisuride, a new semisynthetic ergot derivative. Acute administration of lisuride (100 microgram orally) significantly suppressed serum prolactin (PRL) levels in nine out of eleven subjects. In these nine patients, prolonged treatment wit...

journal_title：Clinical endocrinology

authors： De Cecco L,Foglia G,Ragni N,Rossato P,Venturini PL

更新日期：1978-12-01 00:00:00

abstract：:The identification of genes placing individuals at an increased risk for the development of autoimmune thyroid disease (AITD) has been a slow process. However, over the last 20 years or so real progress has been made with the mapping of novel loci, via a number of different approaches. First, through the use of tradit...

journal_title：Clinical endocrinology

authors： Zeitlin AA,Simmonds MJ,Gough SC

更新日期：2008-05-01 00:00:00

abstract：:The nature of the thyroid disorder presented by patients with normal T4 and T3 but blunted TSH response to TRH has not been clarified. In this study, we compared thyroid function tests in 16 such patients with those of 14 controls and 10 hyperthyroid patients. Basal total T4, free T4, total T3, iodine uptake and chole...

journal_title：Clinical endocrinology

authors： Boutin JM,Matte R,D'Amour P,Gilbert F,Havrankova J,Bélanger R,Chartrand R,Zakarija M

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:The euglycemic-hyperinsulinemic clamp is the gold standard to evaluate insulin resistance (IR), but there are only a few studies on the prevalence of IR in Chinese Han women with polycystic ovary syndrome (PCOS). This study investigated: (a) the prevalence of IR in Chinese Han women with PCOS by clamp, (b) th...

journal_title：Clinical endocrinology

authors： Li W,Chen Q,Xie Y,Hu J,Yang S,Lin M

更新日期：2019-01-01 00:00:00

abstract：:Serum immunoreactive melatonin was measured in thirty-three male subjects with delayed puberty, thirty of whom had simple (idiopathic) delayed puberty (SDP) and three of whom were GH deficient. The results were compared with a control population of twenty-six subjects. Significantly elevated values of serum melatonin ...

journal_title：Clinical endocrinology

authors： Cohen HN,Hay ID,Annesley TM,Beastall GH,Wallace AM,Spooner R,Thomson JA,Eastwold P,Klee GG

更新日期：1982-11-01 00:00:00

abstract：CONTEXT:Unlike pituitary macroadenomas, microadenomas (micros) are not commonly associated with hypopituitarism. In clinical practice, we have observed that patients with ACTH-secreting micros have a higher than expected prevalence of central hypothyroidism (HT), and we speculated that this effect might be because of g...

journal_title：Clinical endocrinology

authors： Mathioudakis N,Thapa S,Wand GS,Salvatori R

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:There has been a rapid shift from open to laparoscopic approaches in adrenal surgery, but the safety and efficacy of bilateral laparoscopic adrenalectomy (BLA) in patients with corticotrophin (ACTH)-dependent Cushing's syndrome continues to be defined. OBJECTIVE:Review outcomes in the largest series of pati...

journal_title：Clinical endocrinology

authors： Chow JT,Thompson GB,Grant CS,Farley DR,Richards ML,Young WF Jr

更新日期：2008-04-01 00:00:00

abstract：:The results obtained with a new test of prolactin (PRL) release in six panhypopituitary patients as compared to fourteen normal subjects (eight females and six males) are presented. The test consists of the i.m. administration of 100 mg of sulpiride and the measurement of plasma PRL by a double antibody radioimmunoass...

journal_title：Clinical endocrinology

authors： Batrinos ML,Pavlou SN,Pitoulis SA,Sfikaki AP,Alexandrides TK,Piaditis GP

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Obestatin is a novel hormone that is encoded by the Ghrelin gene and produced in the gut. Ghrelin is profoundly orexogenic and adipogenic, increasing food intake and body weight. This new ghrelin-associated peptide behaves as a physiological opponent of ghrelin in rodent animals, but its pathophysiological r...

journal_title：Clinical endocrinology

authors： Qi X,Li L,Yang G,Liu J,Li K,Tang Y,Liou H,Boden G

更新日期：2007-04-01 00:00:00