The effect of lisuride hydrogen maleate in the hyperprolactinaemia-amenorrhoea syndrome: clinical and hormonal responses.

abstract：CONTEXT:Steroid 5α-reductase type 2 deficiency (5α-RD2) is a male-limited, autosomal recessive inherited disease. Affected 46, XY individuals usually present with ambiguous genitalia at birth. An early and precise diagnosis is of great value to the long-term prognosis of the disease. OBJECTIVE:To describe the clinical...

journal_title：Clinical endocrinology

authors： Zhu H,Liu W,Han B,Fan M,Zhao S,Wang H,Lu Y,Pan C,Chen F,Chen M,Song H,Cheng K,Qiao J

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:We determined the ovarian response to human chorionic gonadotrophin (hCG) in terms of relaxin and progesterone secretion during the peri-implantation period of normal and failing pregnancies. We wished to test the hypotheses that relaxin production in failing pregnancies is different from that in normal pregn...

journal_title：Clinical endocrinology

authors： Stewart DR,Overstreet JW,Celniker AC,Hess DL,Cragun JR,Boyers SP,Lasley BL

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:Pseudohypoparathyroidism type Ia (PHP-Ia) is a hereditary disorder characterized by resistance to multiple hormones that work via cAMP such as PTH and TSH, accompanied by typical skeletal features including short stature and brachydactyly, termed Albright hereditary osteodystrophy (AHO). In affected kindreds,...

journal_title：Clinical endocrinology

authors： Mouallem M,Shaharabany M,Weintrob N,Shalitin S,Nagelberg N,Shapira H,Zadik Z,Farfel Z

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Although autoantibody production is a key feature of autoimmunity, it is not known whether variation in autoantibody production and clearance pathways is involved in disease susceptibility. The Fc Gamma Receptor IIa (FcGRIIa) molecule is involved in the clearance of autoantibodies and a functional single nucl...

journal_title：Clinical endocrinology

authors： Yesmin K,Hargreaves C,Newby PR,Brand OJ,Heward JM,Franklyn JA,Gough SC,Simmonds MJ

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Controversial data on ghrelin concentration during exercise in human subjects have been published. We tested the hypothesis that exercise could affect acylated ghrelin (AG) and unacylated ghrelin (UAG), which could partly explain the previously reported inconsistent findings on the association of exercise wit...

journal_title：Clinical endocrinology

authors： Kim HJ,Lee S,Kim TW,Kim HH,Jeon TY,Yoon YS,Oh SW,Kwak H,Lee JG

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:Patients on long-term dialysis may develop secondary hyperparathyroidism (SHPT), which causes varying degrees of bone mass loss. This condition is treated with parathyroidectomy (PTX). We investigated whether serial serum bone turnover markers could predict changes in bone mineral density (BMD) after PTX. DE...

journal_title：Clinical endocrinology

authors： Lu KC,Ma WY,Yu JC,Wu CC,Chu P

更新日期：2012-05-01 00:00:00

abstract：:Raised activity of the LH axis caused by activating mutations of LH receptor gene presents with precocious puberty in boys, analogous to the presentation of LH secreting pituitary adenomas (Faggiano et al., 1983; Ambrosi et al., 1990). LH "hyperactivity' in females appears to have no effect. Hyperactivity of the FSH a...

journal_title：Clinical endocrinology

authors： Conway GS

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVES:Alterations in protein expression of histone deacetylase 2 (HDAC2) have been demonstrated in various neoplasms, and lack of nuclear expression of HDAC2 has previously been shown in some human and canine corticotroph adenomas. This study aimed to examine HDAC2 expression in a Norwegian cohort of corticotroph ...

journal_title：Clinical endocrinology

authors： Evang JA,Borota OC,Melum E,Holm R,Ramm-Pettersen J,Bollerslev J,Berg JP

更新日期：2010-08-01 00:00:00

abstract：CONTEXT:Few studies have evaluated the metabolic outcomes of growth hormone (GH) treatment in idiopathic short stature (ISS). Moreover, children with ISS appear to need higher GH doses than children with GH deficiency (GHD) to achieve the same amount of growth and may therefore be at increased risk of adverse events du...

journal_title：Clinical endocrinology

authors： Decker R,Albertsson-Wikland K,Kriström B,Nierop AF,Gustafsson J,Bosaeus I,Fors H,Hochberg Z,Dahlgren J

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To evaluate whether thyroid scintigraphy would alter the clinical management of patients referred for fine-needle aspiration cytology (FNA). METHODS:We reviewed the medical and imaging records of patients referred to our Department between 2016 and 2019. All the patients had to take a serum thyrotropin test ad...

journal_title：Clinical endocrinology

authors： Pirola I,Di Lodovico E,Casella C,Pezzaioli L,Facondo P,Ferlin A,Lombardi D,Cappelli C

更新日期：2020-12-17 00:00:00

abstract：OBJECTIVE:To evaluate the impact of maternal hypothyroxinaemia during early gestation (fT4 below the lowest tenth percentile and TSH within the reference range: 0.15-2.0 mIU/l) on infant development, together with any subsequent changes in fT4 during gestation. DESIGN:A prospective 3-year follow-up study of pregnant w...

journal_title：Clinical endocrinology

authors： Pop VJ,Brouwers EP,Vader HL,Vulsma T,van Baar AL,de Vijlder JJ

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:The protein polymorphism of the GH receptor caused by genomic deletion of exon 3 (d3) has been linked to the magnitude of the first-year-growth response to GH in girls with Turner syndrome. Here, we studied the long-term effect of GH therapy in Turner syndrome in correlation to this polymorphism. DESIGN:The ...

journal_title：Clinical endocrinology

authors： Binder G,Trebar B,Baur F,Schweizer R,Ranke MB

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Adrenal disorders such as congenital adrenal hyperplasia result in abnormal adrenal size and morphology, but little is known about the clinical value of magnetic resonance imaging (MRI) in determining adrenal volume. OBJECTIVE:To evaluate the potential usefulness of MR methodology, to estimate adrenal size ...

journal_title：Clinical endocrinology

authors： Mouritsen A,Johansen ML,Wohlfahrt-Veje C,Hagen CP,Tinggaard J,Mieritz MG,Tefre de Renzy-Martin K,Soeborg T,Fallentin E,Juul A,Main KM

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:Mutations in the dual oxidase 2 gene (DUOX2) is the most common genetic cause of congenital hypothyroidism (CH) in Japan. All previously described DUOX2 mutation-carrying families have followed autosomal recessive inheritance. We report a nonconsanguineous Japanese family harbouring biallelic DUOX2 mutations...

journal_title：Clinical endocrinology

authors： Abe K,Narumi S,Suwanai AS,Hamajima T,Hasegawa T

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:The standard ACTH test in clinical use employs a pharmacological dose of ACTH which assesses the maximum secretory capacity of the adrenal cortex. We have investigated the responses of plasma adrenocortical steroids including cortisol, aldosterone and dehydroepiandrosterone (DHEA) to physiological doses of AC...

journal_title：Clinical endocrinology

authors： Daidoh H,Morita H,Mune T,Murayama M,Hanafusa J,Ni H,Shibata H,Yasuda K

更新日期：1995-09-01 00:00:00

abstract：:The measurement of serum intact parathyroid hormone (PTH) (1-84) over a 24-h period has shown the existence of a circadian rhythm in normal males which is absent in patients with primary hyperparathyroidism. The physiological significance of this observation is reflected in the presence of parallel changes in nephroge...

journal_title：Clinical endocrinology

authors： Logue FC,Fraser WD,Gallacher SJ,Cameron DA,O'Reilly DS,Beastall GH,Patel U,Boyle IT

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:This study was conducted to determine the effects of folate supplementation on inflammatory factors and biomarkers of oxidative stress among women with polycystic ovary syndrome (PCOS). DESIGN, PATIENTS AND MEASUREMENTS:This randomized, double-blind, placebo-controlled clinical trial was conducted among 69 w...

journal_title：Clinical endocrinology

authors： Bahmani F,Karamali M,Shakeri H,Asemi Z

更新日期：2014-10-01 00:00:00

abstract：INTRODUCTION:Iodine deficiency in pregnancy may impair foetal neurological development. The UK population is generally thought to be iodine sufficient; however, recent studies have questioned this assumption. Our study aimed to explore the prevalence of iodine deficiency in a cohort of pregnant mothers from South-West ...

journal_title：Clinical endocrinology

authors： Knight BA,Shields BM,He X,Pearce EN,Braverman LE,Sturley R,Vaidya B

更新日期：2017-03-01 00:00:00

abstract：CONTEXT:Childbearing is considered to be a significant risk factor for developing overweight and obesity. Physical activity might influence weight change via hormonal changes. OBJECTIVE:To test the hypothesis that higher levels of moderate-to-vigorous intensity physical activity (MVPA) are positively associated with m...

journal_title：Clinical endocrinology

authors： van der Wijden CL,Delemarre-van de Waal HA,van Mechelen W,van Poppel MN

更新日期：2015-01-01 00:00:00

abstract：:Bilateral, selective and simultaneous catheterization of the inferior petrosal sinus with measurements of ACTH after stimulation with ovine corticotrophin-releasing factor (CRF) is now frequently used to establish the differential diagnosis in patients with Cushing's disease and to determine the side of the microadeno...

journal_title：Clinical endocrinology

authors： Schulte HM,Allolio B,Günther RW,Benker G,Winkelmann W,Ohnhaus EE,Reinwein D

更新日期：1988-03-01 00:00:00

abstract：:The excretion of FSH, LH, oestrogens and pregnanediol was monitored once weekly in urine samples collected from eight peri-menopausal women aged 44-55 years (median, 52 years). Observations were commenced between 5 and 15 weeks before the menopause and were continued for 22-30 weeks after final menstruation. Amenorrho...

journal_title：Clinical endocrinology

authors： Metcalf MG,Donald RA,Livesey JH

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:Glucagon-like peptide-1 is an insulin secretion-stimulating gut hormone that is produced in response to food intake. Orlistat (Xenical, F. Hoffman-La Roche, Basel, Switzerland), which decreases fat absorption and increases intestinal fat content, may therefore affect the secretion of glucagon-like peptide-1. ...

journal_title：Clinical endocrinology

authors： Sahin M,Tanaci N,Yucel M,Tutuncu NB,Guvener N

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To compare biochemical variables, renal function and calcium and vitamin D intakes in euparathyroid and hyperparathyroid patients with primary osteoporosis and osteopenia and describe the measures necessary to normalize serum PTH in the patients with secondary hyperparathyroidism. DESIGN AND PATIENTS:We revi...

journal_title：Clinical endocrinology

authors： Yendt ER,Kovacs KA,Jones G

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:We wished to investigate the effects of nicotinamide and 3-aminobenzamide, well known as inhibitors of poly(ADP ribose) synthetase, on interferon-gamma-induced HLA-DR antigen expression using cultured human thyroid cells from patients with Graves' disease. DESIGN AND MEASUREMENTS:Cultured thyroid cells were ...

journal_title：Clinical endocrinology

authors： Hiromatsu Y,Sato M,Yamada K,Nonaka K

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:We assessed body composition, bone mineral density (BMD), glucose and lipids in Williams syndrome (WS), a rare microdeletion disorder. DESIGN:Individuals with WS had outpatient assessment at Massachusetts General Hospital. Controls were selected from the National Health and Nutrition Examination Survey (NHAN...

journal_title：Clinical endocrinology

authors： Shaikh S,Waxler JL,Lee H,Grinke K,Garry J,Pober BR,Stanley TL

更新日期：2018-11-01 00:00:00

abstract：:Recent evidence suggests that oxytocin (OXT) and arginine vasopressin (AVP) are involved in the response to stress. We have examined the changes in peripheral plasma OXT during abdominal surgery in eight patients (six males, two female; ages 60-82 years) undergoing hemicolectomy and compared the results with those for...

journal_title：Clinical endocrinology

authors： Nussey SS,Page SR,Ang VT,Jenkins JS

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:We have evaluated the efficacy of percutaneous ethanol injection as an alternative to surgery and iodine-131 treatment in solitary autonomous thyroid adenoma. DESIGN:Percutaneous ethanol injection (0.5-2.8 ml ethanol/ml nodular tissue) was performed under sonographic guidance in 3-5 (1-2 weekly) sessions; a ...

journal_title：Clinical endocrinology

authors： Monzani F,Goletti O,Caraccio N,Del Guerra P,Ferdeghini M,Pucci E,Baschieri L

更新日期：1992-05-01 00:00:00

abstract：:Using a sensitive enzyme amplified immunoassay for TSH, the evening rise and pulsatile release of TSH were studied in 10 men with chronic renal failure treated by haemodialysis. Compared to euthyroid male controls the evening rise of TSH was attenuated (median 0.066 vs 0.195 mU/l/h, P less than 0.01) and the rate of r...

journal_title：Clinical endocrinology

authors： Wheatley T,Clark PM,Clark JD,Holder R,Raggatt PR,Evans DB

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To study the relationship between the excretion of nephrogenous cyclic AMP (NcAMP) and other blood and urine parameters as an index of PTH-like activity in patients with primary hepatocellular carcinoma. DESIGN:After overnight fast, a double voided urine and a blood sample were collected from each subject fo...

journal_title：Clinical endocrinology

authors： Panesar NS,Au KM,Leung NW,Shek CC,Swaminathan R

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:Adrenal crises are potentially life-threatening complications in patients with adrenal insufficiency (AI). Our objective was to investigate the frequency of adrenal crises in different forms of AI. DESIGN/PATIENTS:The Statutory Health Insurance (SHI) database of the Techniker Krankenkasse - covering more tha...

journal_title：Clinical endocrinology

authors： Meyer G,Badenhoop K,Linder R

更新日期：2016-09-01 00:00:00