The Effects of Highly Challenging Balance Training in Elderly With Parkinson's Disease: A Randomized Controlled Trial.

Abstract:

BACKGROUND:Highly challenging exercises have been suggested to induce neuroplasticity in individuals with Parkinson's disease (PD); however, its effect on clinical outcomes remains largely unknown. OBJECTIVE:To evaluate the short-term effects of the HiBalance program, a highly challenging balance-training regimen that incorporates both dual-tasking and PD-specific balance components, compared with usual care in elderly with mild to moderate PD. METHODS:Participants with PD (n = 100) were randomized, either to the 10-week HiBalance program (n = 51) or to the control group (n = 49). Participants were evaluated before and after the intervention. The main outcomes were balance performance (Mini-BESTest), gait velocity (during normal and dual-task gait), and concerns about falling (Falls Efficacy Scale-International). Performance of a cognitive task while walking, physical activity level (average steps per day), and activities of daily living were secondary outcomes. RESULTS:A total of 91 participants completed the study. After the intervention, the between group comparison showed significantly improved balance and gait performance in the training group. Moreover, although no significant between group difference was observed regarding gait performance during dual-tasking; the participants in the training group improved their performance of the cognitive task while walking, as compared with the control group. Regarding physical activity levels and activities of daily living, in comparison to the control group, favorable results were found for the training group. No group differences were found for concerns about falling. CONCLUSIONS:The HiBalance program significantly benefited balance and gait abilities when compared with usual care and showed promising transfer effects to everyday living. Long-term follow-up assessments will further explore these effects.

authors

Conradsson D,Löfgren N,Nero H,Hagströmer M,Ståhle A,Lökk J,Franzén E

doi

10.1177/1545968314567150

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

827-36

issue

9

eissn

1545-9683

issn

1552-6844

pii

1545968314567150

journal_volume

29

pub_type

杂志文章,随机对照试验
  • Longitudinal analysis of balance confidence in individuals with stroke using a multilevel model for change.

    abstract:BACKGROUND:Confidence about balance may be an important factor affecting self-efficacy for daily activities after stroke. OBJECTIVE:The authors investigated whether confidence changes and the parameters that may predict changes in self-perceived balance within the first year of community reintegration. METHODS:In thi...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968312437941

    authors: Yiu J,Miller WC,Eng JJ,Liu Y

    更新日期:2012-10-01 00:00:00

  • How long is the recovery of global aphasia? Twenty-five years of follow-up in a patient with left hemisphere stroke.

    abstract:BACKGROUND:Current knowledge regarding the time course of aphasia recovery is based on observations limited to the first years after stroke. OBJECTIVE:The authors studied long-term outcome (25 years) of language in a patient with global aphasia. METHODS:A 37-year-old man with global aphasia from a large ischemic lesi...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968310368962

    authors: Smania N,Gandolfi M,Aglioti SM,Girardi P,Fiaschi A,Girardi F

    更新日期:2010-11-01 00:00:00

  • Brain-computer interface with language model-electroencephalography fusion for locked-in syndrome.

    abstract:BACKGROUND:Some noninvasive brain-computer interface (BCI) systems are currently available for locked-in syndrome (LIS) but none have incorporated a statistical language model during text generation. OBJECTIVE:To begin to address the communication needs of individuals with LIS using a noninvasive BCI that involves rap...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968313516867

    authors: Oken BS,Orhan U,Roark B,Erdogmus D,Fowler A,Mooney A,Peters B,Miller M,Fried-Oken MB

    更新日期:2014-05-01 00:00:00

  • Motor training of upper extremity with functional electrical stimulation in early stroke rehabilitation.

    abstract:BACKGROUND:Functional electrical stimulation (FES) allows active exercises in stroke patients with upper extremity paralysis. OBJECTIVE:To investigate the effect of motor training with FES on motor recovery in acute and subacute stroke patients with severe to complete arm and/or hand paralysis. METHODS:For this pilot...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968308324548

    authors: Mangold S,Schuster C,Keller T,Zimmermann-Schlatter A,Ettlin T

    更新日期:2009-02-01 00:00:00

  • Upper limb robot-assisted therapy in cerebral palsy: a single-blind randomized controlled trial.

    abstract:BACKGROUND:Several pilot studies have evoked interest in robot-assisted therapy (RAT) in children with cerebral palsy (CP). OBJECTIVE:To assess the effectiveness of RAT in children with CP through a single-blind randomized controlled trial. PATIENTS AND METHODS:Sixteen children with CP were randomized into 2 groups. ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968314541172

    authors: Gilliaux M,Renders A,Dispa D,Holvoet D,Sapin J,Dehez B,Detrembleur C,Lejeune TM,Stoquart G

    更新日期:2015-02-01 00:00:00

  • Safety of 6-Hz primed low-frequency rTMS in stroke.

    abstract:BACKGROUND:Suppression of activity in the contralesional motor cortex may promote recovery of function after stroke. Furthermore, the known depressant effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) can be increased and prolonged by preceding it with 6-Hz priming stimulation. OBJECTIVE:The...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 临床试验,杂志文章

    doi:10.1177/1545968307305458

    authors: Carey JR,Evans CD,Anderson DC,Bhatt E,Nagpal A,Kimberley TJ,Pascual-Leone A

    更新日期:2008-03-01 00:00:00

  • Development of a health-related quality of life measure for peripheral neuropathy.

    abstract:STATEMENT OF PROBLEM:To develop and evaluate a self-administered health-related quality of life (HRQOL) measure for peripheral neuropathy. METHODS:A field test measure of 162 items was developed that included the RAND-36 Health Survey as a generic core and a neuropathy-targeted supplement whose content was driven by r...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/154596830001400202

    authors: Vickrey BG,Hays RD,Beckstrand M

    更新日期:2000-01-01 00:00:00

  • Combined analysis of cortical (EEG) and nerve stump signals improves robotic hand control.

    abstract:BACKGROUND:Interfacing an amputee's upper-extremity stump nerves to control a robotic hand requires training of the individual and algorithms to process interactions between cortical and peripheral signals. OBJECTIVE:To evaluate for the first time whether EEG-driven analysis of peripheral neural signals as an amputee ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968311408919

    authors: Tombini M,Rigosa J,Zappasodi F,Porcaro C,Citi L,Carpaneto J,Rossini PM,Micera S

    更新日期:2012-03-01 00:00:00

  • Use-dependent up- and down-regulation of sensorimotor brain circuits in stroke patients.

    abstract:OBJECTIVE:To examine whether cerebral activity during passive movements decreases with time after stroke, and if reduced activity in the representation for the upper extremity can be reversed with training. METHODS:Brain activity was measured by functional magnetic resonance imaging (fMRI) during passive wrist flexion...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 临床试验,杂志文章

    doi:10.1177/1545968306296965

    authors: Lindberg PG,Schmitz C,Engardt M,Forssberg H,Borg J

    更新日期:2007-07-01 00:00:00

  • A single injection of D-amphetamine facilitates improvements in motor training following a focal cortical infarct in squirrel monkeys.

    abstract:BACKGROUND:There is growing interest in the use of D-amphetamine (D-AMPH) as a pharmacological treatment to supplement rehabilitative therapy following stroke. Based on the success of earlier animal models, several clinical studies have demonstrated beneficial effects of applying physical rehabilitation while stroke pa...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968306290773

    authors: Barbay S,Zoubina EV,Dancause N,Frost SB,Eisner-Janowicz I,Stowe AM,Plautz EJ,Nudo RJ

    更新日期:2006-12-01 00:00:00

  • Training-induced brain remapping in chronic aphasia: a pilot study.

    abstract:BACKGROUND:The neural correlates of training-induced improvements of cognitive functions after brain damage remain still scarcely understood. In the specific case of aphasia, although several investigations have addressed the issue of the neural substrates of functional recovery, only a few studies have attempted to as...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 临床试验,杂志文章

    doi:10.1177/1545968306294735

    authors: Vitali P,Abutalebi J,Tettamanti M,Danna M,Ansaldo AI,Perani D,Joanette Y,Cappa SF

    更新日期:2007-03-01 00:00:00

  • Time course of cortical plasticity after facial nerve palsy: a single-case study.

    abstract:BACKGROUND:Functional connectivity is defined as the temporal correlation between spatially remote neurophysiological events. This method has become particularly useful for studying neuroplasticity to detect changes in the collaboration of brain areas during cortical reorganization. METHODS:In this article, the author...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968311418674

    authors: Klingner CM,Volk GF,Brodoehl S,Burmeister HP,Witte OW,Guntinas-Lichius O

    更新日期:2012-02-01 00:00:00

  • Longitudinal evaluation of resting-state FMRI after acute stroke with hemiparesis.

    abstract:BACKGROUND:Functional magnetic resonance imaging (fMRI) of motor impairment after stroke strongly depends on patient effort and capacity to make a movement. Hence fMRI has had limited use in clinical management. Alternatively, resting-state fMRI (ie, with no task) can elucidate the brain's functional connections by det...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968312457827

    authors: Golestani AM,Tymchuk S,Demchuk A,Goodyear BG,VISION-2 Study Group.

    更新日期:2013-02-01 00:00:00

  • Enhancing the Alignment of the Preclinical and Clinical Stroke Recovery Research Pipeline: Consensus-Based Core Recommendations From the Stroke Recovery and Rehabilitation Roundtable Translational Working Group.

    abstract::Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery. ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1177/1545968317724285

    authors: Corbett D,Carmichael ST,Murphy TH,Jones TA,Schwab ME,Jolkkonen J,Clarkson AN,Dancause N,Weiloch T,Johansen-Berg H,Nilsson M,McCullough LD,Joy MT

    更新日期:2017-08-01 00:00:00

  • Roles of Lesioned and Nonlesioned Hemispheres in Reaching Performance Poststroke.

    abstract::Background. Severe poststroke arm impairment is associated with greater activation of the nonlesioned hemisphere during movement of the affected arm. The circumstances under which this activation may be adaptive or maladaptive remain unclear. Objective. To identify the functional relevance of key lesioned and nonlesio...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968319876253

    authors: Harrington RM,Chan E,Rounds AK,Wutzke CJ,Dromerick AW,Turkeltaub PE,Harris-Love ML

    更新日期:2020-01-01 00:00:00

  • Understanding inconsistent step-length asymmetries across hemiplegic stroke patients: impairments and compensatory gait.

    abstract:BACKGROUND:In hemiplegic gait, step length typically differs in magnitude between paretic and nonparetic sides. However, the direction of step-length asymmetry varies across stroke patients. OBJECTIVE:The study sought to understand directional variations in step-length asymmetry in terms of asymmetries in forward foot...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968310380687

    authors: Roerdink M,Beek PJ

    更新日期:2011-03-01 00:00:00

  • Searching for the "Active Ingredients" in Physical Rehabilitation Programs Across Europe, Necessary to Improve Mobility in People With Multiple Sclerosis: A Multicenter Study.

    abstract:BACKGROUND:Physical rehabilitation programs can lead to improvements in mobility in people with multiple sclerosis (PwMS). OBJECTIVE:To identify which rehabilitation program elements are employed in real life and how they might affect mobility improvement in PwMS. METHODS:Participants were divided into improved and n...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1545968319834893

    authors: Kalron A,Feys P,Dalgas U,Smedal T,Freeman J,Romberg A,Conyers H,Elorriaga I,Gebara B,Merilainen J,Heric-Mansrud A,Jensen E,Jones K,Knuts K,Maertens de Noordhout B,Martic A,Normann B,O Eijnde B,Rasova K,Santoyo Medin

    更新日期:2019-04-01 00:00:00

  • Test-retest reliability of portable metabolic monitoring after disabling stroke.

    abstract:PURPOSE:Impaired economy of gait, prevalent in chronic stroke secondary to residual gait deficits, is associated with intolerance for performing activities of daily living. Gait economy/efficiency is traditionally assessed by determining the rate of oxygen consumption during submaximal treadmill walking. However, the m...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968313497103

    authors: Stookey AD,McCusker MG,Sorkin JD,Katzel LI,Shaughnessy M,Macko RF,Ivey FM

    更新日期:2013-11-01 00:00:00

  • Caregiver-mediated intervention can improve physical functional recovery of patients with chronic stroke: a randomized controlled trial.

    abstract::Background and Purpose. Patients with chronic stroke may benefit from continuing rehabilitation training after hospital discharge. This study examined whether caregiver-mediated, home-based intervention (CHI) could improve physical functioning and social participation in these patients. Methods. A single-blind, random...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/1545968314532030

    authors: Wang TC,Tsai AC,Wang JY,Lin YT,Lin KL,Chen JJ,Lin BY,Lin TC

    更新日期:2015-01-01 00:00:00

  • Recovery rates after stroke and their impact on outcome prediction.

    abstract::Current assessments do not provide reliable factors predictive of outcome from stroke for stroke survivors of intermediate age and severity of deficit. We sought to investigate whether early rate of functional improvement can facilitate prediction of functional outcome, length of stay, and disposition beyond that affo...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/154596830001400309

    authors: Ween JE,Mernoff ST,Alexander MP

    更新日期:2000-01-01 00:00:00

  • Defining the role of sensation, strength, and prehension for upper limb function in cervical spinal cord injury.

    abstract:BACKGROUND:Upper limb function plays a significant role in enhancing independence for individuals with tetraplegia. However, there is limited knowledge about the specific input of sensorimotor deficits on upper limb function. Thus the theoretical framework designed to develop the Graded Redefined Assessment of Strength...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968313490998

    authors: Kalsi-Ryan S,Beaton D,Curt A,Duff S,Jiang D,Popovic MR,Rudhe C,Fehlings MG,Verrier MC

    更新日期:2014-01-01 00:00:00

  • Spaced Noninvasive Brain Stimulation: Prospects for Inducing Long-Lasting Human Cortical Plasticity.

    abstract::Neuroplasticity is critical for learning, memory, and recovery of lost function following neurological damage. Noninvasive brain stimulation (NIBS) techniques can induce neuroplastic changes in the human cortex that are behaviorally relevant, raising the exciting possibility that these techniques might be therapeutica...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968314562649

    authors: Goldsworthy MR,Pitcher JB,Ridding MC

    更新日期:2015-09-01 00:00:00

  • Psychometric properties of the HRQOLISP-40: a novel, shortened multiculturally valid holistic stroke measure.

    abstract:BACKGROUND:A recent review showed that no existing instrument measured the entire spectrum of health-related quality of life (HRQOL) in stroke patients. However, the HRQOL in stroke patients (HRQOLISP) questionnaire is valid and exceptionally comprehensive. Founded on a holistic model of human life, it comprises both p...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1545968310369113

    authors: Ojo Owolabi M

    更新日期:2010-11-01 00:00:00

  • Kinematics of turning 180 degrees during the timed up and go in stroke survivors with and without falls history.

    abstract:BACKGROUND:Community-dwelling, chronic stroke survivors are at risk of falling during turning and are more likely to sustain a hip fracture when they fall. OBJECTIVE:This study quantifies kinematic differences between stroke survivors (mean +/- SD: 38.3 +/- 31.3 months post-stroke, 59.9 +/- 10.1 years of age), with (n...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968309348508

    authors: Hollands KL,Hollands MA,Zietz D,Wing AM,Wright C,van Vliet P

    更新日期:2010-05-01 00:00:00

  • Neuropathic Pain in Taxane-Induced Peripheral Neuropathy: Evidence for Exercise in Treatment.

    abstract::One in 2 Canadians is expected to acquire cancer in their lifetime. Many cancers, including breast, ovarian, and lung cancer, are treated using taxane chemotherapy with curative intent. A major adverse effect with the use of taxane chemotherapeutic agents is taxane-induced peripheral neuropathy (TIPN). Both positive (...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,评审

    doi:10.1177/1545968319860486

    authors: Andersen Hammond E,Pitz M,Shay B

    更新日期:2019-10-01 00:00:00

  • Identifying Homogeneous Subgroups in Neurological Disorders: Unbiased Recursive Partitioning in Cervical Complete Spinal Cord Injury.

    abstract::Background The reliable stratification of homogeneous subgroups and the prediction of future clinical outcomes within heterogeneous neurological disorders is a particularly challenging task. Nonetheless, it is essential for the implementation of targeted care and effective therapeutic interventions. Objective This stu...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1545968313520413

    authors: Tanadini LG,Steeves JD,Hothorn T,Abel R,Maier D,Schubert M,Weidner N,Rupp R,Curt A

    更新日期:2014-07-01 00:00:00

  • Upper Limb Recovery in Spinal Cord Injury: Involvement of Central and Peripheral Motor Pathways.

    abstract:BACKGROUND AND OBJECTIVE:The course of central and peripheral motor recovery after cervical spinal cord injury (SCI) may be investigated by electrophysiological measures. The goal of this study was to compare the 2 over the first year after injury in relation to motor gains. METHODS:Compound motor action potentials (C...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1545968316688796

    authors: Petersen JA,Spiess M,Curt A,Weidner N,Rupp R,Abel R,EM-SCI Study Group.,Schubert M

    更新日期:2017-05-01 00:00:00

  • Does functional electrical stimulation for foot drop strengthen corticospinal connections?

    abstract:BACKGROUND:Long-term use of a foot-drop stimulator applying functional electrical stimulation (FES) to the common peroneal nerve improves walking performance even when the stimulator is off. This "therapeutic" effect might result from neuroplastic changes. OBJECTIVE:To determine the effect of long-term use of a foot-d...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 临床试验,杂志文章

    doi:10.1177/1545968309349939

    authors: Everaert DG,Thompson AK,Chong SL,Stein RB

    更新日期:2010-02-01 00:00:00

  • Impaired Functional Connectivity Unmasked by Simple Repetitive Motor Task in Early Relapsing-Remitting Multiple Sclerosis.

    abstract:BACKGROUND:Resting brain activity can be modulated by motor tasks to adapt to function. In multiple sclerosis (MS) patients, altered resting-state functional connectivity (RS-FC) has been reported and associated with impaired function and disability; little is known on how RS-FC is modulated by a simple repetitive moto...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968314558600

    authors: Petsas N,Tomassini V,Filippini N,Sbardella E,Tona F,Piattella MC,Pozzilli C,Wise RG,Pantano P

    更新日期:2015-07-01 00:00:00

  • Physiological responses to two wheelchair-racing exercise protocols.

    abstract:OBJECTIVE:This study investigated the blood lactate accumulation during two wheelchair-racing protocols. During exercise, energy is required, which causes metabolism to increase and blood lactate to accumulate. Proper training can reduce the amount of blood lactate accumulation and increase tolerance to blood lactate a...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/154596830101500306

    authors: Cooper RA,Baldini FD,Boninger ML,Cooper R

    更新日期:2001-01-01 00:00:00