Abstract：
BACKGROUND:Regulation of reproduction is now considered to be carried out by the kisspeptin and its receptor, GPR54 or Kiss1r. Mutations of either Kiss1 or Kiss1r in humans and mice result in profound hypogonadotropic hypogonadism. The present study was aimed to determine whether the levels of kisspeptin are associated with male infertility. METHODOLOGY:The study involved 176 male subjects aged 18 - 50 years including 26 fertile and 150 infertile. Infertile subjects were further subdivided according to WHO guidelines of semen analysis into 22 asthenozoospermia, 08 asthenoteratozoospermia, 18 azoospermia, 58 normozoospermia, 06 oligozoospermia, 12 oligoasthenozoospermia and 26 oligoasthenoteratozoospermia. Thorough clinical examinations excluded those suffering from chronic health problems. Serum kisspeptin levels were measured by enzyme immunoassay (EIA) and follicle stimulating hormone (FSH), luteinizing hormone (LH) and testosterone were estimated by chemiluminescence assay (CLIA). RESULTS:The results of the present study have revealed that kisspeptin levels were significantly lower in all infertile males as compared to the fertile males. Significantly low LH and testosterone levels were observed in all infertile groups as compared to fertile group. FSH levels were significantly lower in normozoospermic and azoospermic as compared to fertile males, while no significant difference was observed between the other infertile and fertile group. CONCLUSION:The study revealed that serum kisspeptin levels were observed significantly lower in the infertile as compared to fertile males, indicating that the kisspeptin might be associated with the fertility problems in males.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Ramzan MH,Ramzan M,Ramzan F,Wahab F,Jelani M,Khan MA,Shah Mdoi
0151801/AIM.005subject
Has Abstractpub_date
2015-01-01 00:00:00pages
12-7issue
1eissn
1029-2977issn
1735-3947pii
005journal_volume
18pub_type
杂志文章abstract：:Synchronous development of gastrointestinal stromal tumors with other tumors in the digestive tract is relatively rare, and often occurs in the stomach. We report a 76-year-old woman, who suffered from the exceedingly rare synchronous development of small intestinal stromal tumor and cecal adenocarcinoma. The patient ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:This study was conducted to evaluate the hematological effects of umbilical cord clamp timing and delivery type in term infants 48 hours after birth in Imam Hossein Hospital, Tehran, Iran. METHOD:From Oct 2007 - March 2008, 100 mother-infant eligible pairs were selected and divided by cord clamp timing (< or...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：010135/AIM.0010
更新日期：2010-09-01 00:00:00
abstract：:Several studies have shown that patients with acromegaly are at increased risk of developing colorectal polyps and cancer. The prevalence of polyp in colon of patients with acromegaly was variously reported between 23% and 53%. This study was conducted to determine the prevalence of polyp and cancer of colon in patien...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：07102/AIM.0019
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:The present study aimed to evaluate the correlation of P53 and granzyme B (GB) expression, and also the relationship between P53 expression and GB+ cell density with lymph node metastasis, histologic grade, and inflammation intensity in oral squamous cell carcinoma (OSCC). METHODS:Immunohistochemical techn...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：013169/AIM.003
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Ankylosing spondylitis (AS; OMIM:106300) is a common complex inflammatory disease; in a previous study, we introduced a novel mutation in the RELN gene (OMIM: 600514) which was associated with AS. This study is designed to investigate the potential effect of RELN S2486G mutation on reelin secretion; addition...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：10.34172/aim.2020.87
更新日期：2020-10-01 00:00:00
abstract：:Primitive neuroectodermal tumors (PNETs) are a family of highly malignant soft tissue neoplasms mostly occurring in children and young adults. PNETs usually develop in the thoracopulmonary region, abdomen, pelvis, and rarely in the head and neck region. Here, a case of PNET located in the parotid gland is reported. ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151812/AIM.0012
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:The childhood obesity epidemic is one of the most serious global health challenges, and many relevant policies have been designed and implemented. Regarding health equity policy-making, it is important to adopt proper interventional strategies, including childhood obesity policies. The purpose of this study ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:To evaluate the outcome of laparoendoscopic single-site (LESS-A) through one transumbilical port vs. 3-port laparoscopic (3TA) appendectomy in children. METHODS:We reviewed the records of 309 children (65 LESS-A, 244 3TA) operated on between 2008 and 2012. One hundered forty-nine patients had acute catarrhalis...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161901/AIM.0011
更新日期：2016-01-01 00:00:00
abstract：:Chronic myelogenous leukemia (CML) and tuberculosis (TB) are diseases with effective available therapy. Treating patients who are afflicted simultaneously with both of these conditions is challenging due to significant drug interactions and the requirement of strict adherence to the multi-agent treatment regimen. Here...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151801/AIM.0015
更新日期：2015-01-01 00:00:00
abstract：:Heck's disease or focal epithelial hyperplasia is a benign contagious disease caused by human papillomavirus types 13 or 32. It occurs with low frequency in the Iranian population. This condition is characterized by the occurrence of multiple, small papules or nodules in the oral cavity, especially on the labial and b...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:The present study was conducted to determine the health-related quality of life in patients living with human immunodeficiency virus or suffering from acquired immune deficiency syndrome (HIV/AIDS), referred to Behavioral Diseases Consultation Center in west of Tehran, Iran. METHODS:This cross-sectional stu...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：BACKGROUND:The threshold of thyroid-stimulating hormone (TSH) in current screening for congenital hypothyroidism (CH) from the heel prick test is 5 mU/l. This study uses cost-effective analysis to evaluate increasing the threshold to minimize false-positive results and recall rates. METHODS:Cost of screening, diagnosi...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：012153/AIM.006
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:Thalassemia major and its treatment by stem cell transplantation can have deleterious effects on bone integrity. This study assesses the adverse effects of transplantation on growing bones of pediatric thalassemic patients. METHODS:Bone mineral density (BMD) of 20 patients from three thalassemia classes who...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：013162/AIM.008
更新日期：2013-02-01 00:00:00
abstract：:Car accidents and gun-shot injuries are the most common causes of spinal cord injury. Five percent of those patients who have a complete spinal cord injury will experience improvement, to some extent. The lack of specific data in the literature regarding the outcome of earthquake related spinal cord injury justified u...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：010134/AIM.0016
更新日期：2010-07-01 00:00:00
abstract：:Head injury is a common occurrence in motor vehicle accidents. There are numerous causes for cranial nerve injury that include head trauma or other lesions. Few studies regarding cranial nerve injury following mild head trauma (GCS: 14 - 15) exist in the literature. The oculomotor nerve is a somatic and visceral motor...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：012159/AIM.0015
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:The use of endoscopic surgery for nasal and sinus pathologies has revolutionized our approaches towards the diseases of these areas. OBJECTIVE:To report our experience with endoscopic surgery of benign tumors and tumor-like conditions of the nose and paranasal sinuses. METHODS:The medical records of 105 pa...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:Breast cancer is the leading cause of carcinoma death in women. Proper treatment depends on the consideration of molecular biology status of tumor cells, which may determine the patient's treatment and prognosis. To determine the prognostic models for this disease, we evaluated the role of cell proliferation...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,多中心研究
doi：07101/AIM.008
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Co-occurring methamphetamine (METH) use during methadone maintenance therapy (MMT) is a highly prevalent and progressive problem in Iran. There are no registered pharmacological treatments for treating METH use disorder. The present study investigates the potential efficacy of atomoxetine in the treatment of...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Postmenopausal bleeding is a clinically important complaint in general gynecologic practice. The incidence of spontaneous postmenopausal bleeding in the general population is approximately 10 % immediately after menopause, and 5 % in all menopausal women. OBJECTIVES:The study was aimed to reveal the histopa...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0131611/AIM.0011
更新日期：2013-11-01 00:00:00
abstract：:Effective prevention and early diagnostic strategies are the most important public health interventions in gastric cancer, which remains a common malignancy worldwide. Preventive strategies require identification and understanding of environmental risk factors that lead to carcinogenesis. Helicobacter pylori (H. pylor...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,评审
doi：013166/AIM.0010
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:Mucocutaneous candidiasis (almost endogenous) is one of the most common manifestations of human immunodeficiency virus (HIV) infection. The aim of this study was the investigation of colonization patterns of Candida species, particularly C. dubliniensis, among mucosal sites of HIV-positive patients and deter...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：010134/AIM.006
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Alzheimer and Parkinson diseases (AD and PD) are the two most important neurodegenerative disorders. This paper aims to determine the possible molecular linkage between these two common neurodegenerative diseases by a combination of computational investigations. METHODS:According to our aim, common sets of ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161902/AIM.007
更新日期：2016-02-01 00:00:00
abstract：:Vitamin D is a pro-hormone that plays an important role in body calcium regulation. Vitamin D toxicity occurs rarely due to its wide therapeutic index. A 38-year-old Iranian man was admitted to our hospital with a diagnosis of vitamin D toxicity. Laboratory test revealed hypercalcemia and elevated 25-hydroxyvitamin D ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161908/AIM.0013
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Studies on the association between legume intake and metabolic syndrome (MetS) are sparse. The objective of this study is to evaluate the association between legume intake, MetS, and its components. METHODS:This study was conducted on 80 subjects (48% female) with MetS as cases and 160 age and gender-matche...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：012159/AIM.005
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:Little is known about the degree of utilization of information resources on diabetes by general practitioners (GPs) and its impact on their clinical behavior in developing countries. Such information is vital if GPs' diabetes knowledge is to be improved. METHODS:This cross-sectional study recruited 319 GPs ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：012154/AIM.0010
更新日期：2012-04-01 00:00:00
abstract：:Longitudinal studies are very common in medical, behavioral, and interventional sciences. One measure of effect of interest in longitudinal studies is risk ratio, naturally estimated by log-binomial regression which suffers from convergence problem. Odds ratio does not well approximate risk ratio when the outcome is c...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2019-01-01 00:00:00
abstract：:Venous thromboembolism refers to thrombotic events in the venous system that are most commonly manifested as deep vein thromboses in the upper or lower extremity and/or pulmonary embolism. Venous thromboembolism is a common disorder that is associated with significant mortality, morbidity and health care-related cost....
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,评审
doi：
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Growth is an increase in the physical dimensions and its result is a quantitative change in the body. Development is a progressive increase in the skills and functional capacity of a child and its result is a qualitative change in a child's function. METHODS:This investigation was a descriptive, decompositi...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：INTRODUCTION:Successful isolation of mesenchymal stem cells from waste tissues might be extremely promising for developing stem cell-based therapies. This study aimed to explore whether cells retrieved from teeth extracted due to advanced periodontal disease present mesenchymal stem cell-like properties. METHODS:Pulp ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：015184/AIM.004
更新日期：2015-04-01 00:00:00
abstract：:Markers of bone turnover are becoming an important tool for practitioners in the management of osteoporosis. Therefore, it is essential to establish a reference database of the markers before using them in various clinical settings. A total of 785 individuals (37% males, 63% females) without apparent or suggested abno...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,多中心研究
doi：08112/AIM.0015
更新日期：2008-03-01 00:00:00
