Abstract:
:Markers of bone turnover are becoming an important tool for practitioners in the management of osteoporosis. Therefore, it is essential to establish a reference database of the markers before using them in various clinical settings. A total of 785 individuals (37% males, 63% females) without apparent or suggested abnormalities affecting bone mass were randomly selected from 13 clusters in Bushehr Port in southern Iran. The serum CrossLaps ELISA and the N-MID Osteocalcin ELISA were used for the quantitative measurement of CrossLaps and osteocalcin in sera. Bone mineral density was determined for the lumbar spines (L2-L4), proximal femur (neck), and forearm (the distal part) using dual-energy X-ray absorptiometry. Men had higher biochemical serum bone markers (P<0.0001). In women, there were progressive increases in serum CrossLaps after 30 years of age, peaking at >60 years. In men, serum CrossLaps levels were decreased progressively by increases in age, with the peak at 20 - 29 years. In women, there was a significant decrease in serum osteocalcin from 20 - 29 years to 30-49 years, followed by a progressive increases during 50 - 59 years, with the peak at >60 years. In men, the highest concentrations for serum osteocalcin occurred at 20 - 29 years. At all sites checked for bone mineral densitys, women in the high osteocalcin quartile had the lowest mean bone mineral densitys values, but women in the high CrossLaps quartile had the lowest mean bone mineral densitys at lumbar and radial sites. However, in men, bone mineral densitys values at neither site differed between the lowest and the highest quartiles of serum biochemical bone markers. We presented a five- year age-specific mean values of bone markers in a general healthy Iranian population. Only women in the high osteocalcin and CrossLaps quartiles had the lowest mean bone mineral densitys values at the lumbar and radial sites. Our results suggest that the significance of osteoclastic bone resorption or bone formation as a determinant of bone mineral densitys may depend on sex.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Nabipour I,Larijani B,Jafari SM,Amiri M,Amiri Zdoi
08112/AIM.0015subject
Has Abstractpub_date
2008-03-01 00:00:00pages
203-6issue
2eissn
1029-2977issn
1735-3947pii
0015journal_volume
11pub_type
杂志文章,多中心研究abstract:BACKGROUND:Little is known about the degree of utilization of information resources on diabetes by general practitioners (GPs) and its impact on their clinical behavior in developing countries. Such information is vital if GPs' diabetes knowledge is to be improved. METHODS:This cross-sectional study recruited 319 GPs ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:012154/AIM.0010
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Polycystic ovary syndrome is not uncommon in women of reproductive age. We conducted this study to determine the clinical, hormonal, and biochemical effects of metformin therapy on girls with polycystic ovary syndrome. METHODS:In a self-controlled clinical trial conducted at the Gynecology Center of Yahyane...
journal_title:Archives of Iranian medicine
pub_type: 临床试验,杂志文章
doi:07102/AIM.0010
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Estimation of health workforce supply becomes problematic when there is no knowledge about the number of active specialists. The aim of this study is to estimate active specialists and their geographic accessibility in Iran. METHODS:We enrolled all medical specialists from the Iranian Ministry of Health dat...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2020-01-01 00:00:00
abstract::Many reported scientific misconducts included duplication, data fabrication and falsification; but recent fake peer reviews have become strange news for many researchers worldwide. Using gmail and other non-academic emails to correspond with journals should be highly prohibited. Indeed, the dark part of this story is ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Comorbidity of psychiatric disorders and substance abuse can intensify both conditions, and when advanced age is added to the combination, the patient will face a distinctive array of issues. This study evaluated the prevalence of psychiatric disorders in elderly substance users as well as certain related fa...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151811/AIM.003
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Abnormal expression of microRNAs (miRNAs) plays an important role in development of several cancer types, including bladder cancer (BCa). However, the relationship between the ratio of miR-181/miR-100 and the prognosis of BCa has not been studied yet. The aim of this study was to evaluate the expression of m...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0161909/AIM.008
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:We aimed to assess the results of first- and fifth-year outcomes and the effect on quality of life (QoL) of transobturator tape (TOT) treatment in patients with stress urinary incontinence (SUI). METHODS:The patients who underwent TOT surgery between January 2008 and June 2013 were screened retrospectively....
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:10.34172/aim.2020.110
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Coronavirus disease 2019 (COVID-19) has been widespread since late December 2019, with several symptoms related to the upper and lower respiratory system. However, its cardiac manifestations are less frequently studied. We aimed to analyze the available COVID-19 data on acute cardiac injury, using troponin a...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,meta分析
doi:10.34172/aim.2020.107
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:This study determined the importance of including tests for refractive errors in vision screening. METHODS:In this cross-sectional study, we performed a random cluster sampling of schoolchildren in the city of Dezful, Iran. After sampling and obtaining informed written consents from their parents, children ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0011144/AIM.005
更新日期:2011-07-01 00:00:00
abstract::On January 23, 2020, the Chinese government announced the city lockdown of Wuhan. Since then, there have been controversial debates among experts about the efficacy of mass quarantine, the oldest and probably one of the most effective methods for controlling infectious disease outbreaks. The impact of health policymak...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:10.34172/aim.2020.08
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Our aim was to determine the association between age at menarche (AAM) and breast cancer adjusted for recall bias (misclassification) in AAM. METHODS:We have used data provided from a case-control study conducted in Iran from 2005 to 2009. The cases and controls were frequency matched based on 5-year age gr...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the association between Trp719Arg (rs20455) and Coronary Heart Disease (CHD), and also Coronary Heart Disease reduction in individuals with this SNP during statin therapy in southern Iran. It has been shown that rs20455, which could affect the function of kinesin ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151810/AIM.008
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Human rotavirus has now been established as the most important cause of childhood gastroenteritis worldwide. The RNA genomic electrophoretic diversity of group A rotavirus strains in Tehran, Iran, during April 2002 through March 2005, was investigated in 1250 stool specimens. METHODS:Stool samples were obta...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:There is a lack of data regarding the incidence rate, etiology, risk factors, and natural course of thyroid disorders and their relationship with cardiovascular disease and mortality in populations undergoing nutrition transition. Therefore, we aimed to assess the natural course of thyroid disease in Tehrani...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:013167/AIM.0011
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Platelet concentrates (PC) are used in thrombocytopenia and inherited or acquired platelet dysfunction disorders. Thus, retaining the platelets quality and function during storage will lead to desirable outcomes in treatment of such patients. METHODS: In this study, we evaluated 40 PC bags, ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:015182/AIM.0010
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:The probiotic microorganisms are live normal flora that provide nutritional benefits. When probiotic administered in adequate amounts, they also confer a health benefit on the host. Different mechanisms of probiotic effects include the following: stimulating the immune system, modifying the composition of no...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151803/AIM.006
更新日期:2015-03-01 00:00:00
abstract::Despite all the problems caused by the imposed war, sanctions and accidents after the Islamic Revolution, materializing primary health care (PHC) in Iran through establishing the National Health Network (NHN) has had substantial gains. Many health indicators in Iran have undergone significant changes. As an example, t...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:
更新日期:2019-05-01 00:00:00
abstract:INTRODUCTION:This research aims to determine the mental health status of population aged 15 and over in the province of Chaharmahal and Bakhtiari in 2015. METHODS:The statistical population of this cross-sectional field survey consisted of residents of urban and rural areas of Chaharmahal and Bakhtiari in Iran. An est...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Studies on the association between legume intake and metabolic syndrome (MetS) are sparse. The objective of this study is to evaluate the association between legume intake, MetS, and its components. METHODS:This study was conducted on 80 subjects (48% female) with MetS as cases and 160 age and gender-matche...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:012159/AIM.005
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Although serological screening tests for blood-borne hepatitis viruses have effectively reduced the risk of HBV transmission through transfusion of infected blood, there is still a possibility that infected blood units from occult carriers being released into the blood supply. The aim of this study was to de...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:014172/AIM.004
更新日期:2014-02-01 00:00:00
abstract::The early efforts for promotion of public health measures and prevention of fatal epidemic diseases in Iran date back to the second half of the 19th century. Based on historical records, the informal protosanitary councils had existed since the early 1850s, but a new formal health institution called "Sanitary Council"...
journal_title:Archives of Iranian medicine
pub_type: 历史文章,杂志文章
doi:07101/AIM.0028
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Esophageal squamous cell carcinoma (ESCC) is a major health problem in many developing countries including Iran. ESCC has a very poor prognosis, largely due to late diagnosis. As a first step in developing an early detection and treatment program, we conducted a population-based endoscopic screening for ESCC...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:014174/AIM.006
更新日期:2014-04-01 00:00:00
abstract::Between September 2010 and January 2012, four patients in our hospital were observed to have permanent dialysis catheters that adhered to either the SVC or right atrium. The first patient underwent intraoperative fluoroscopy and was scheduled for cardiac surgery. Unfortunately due to metabolic disturbances, the patien...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:013164/AIM.0011
更新日期:2013-04-01 00:00:00
abstract::Chronic myelogenous leukemia (CML) and tuberculosis (TB) are diseases with effective available therapy. Treating patients who are afflicted simultaneously with both of these conditions is challenging due to significant drug interactions and the requirement of strict adherence to the multi-agent treatment regimen. Here...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151801/AIM.0015
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Serotonin receptors such as 5-HT3 plays critical role in regulation of sleep, wake cycle and cognitive process. Thus, we investigated the role of CA1 5HT3 serotonin receptors in memory acquisition deficit induced by total sleep deprivation (TSD; for 24 hour) and REM sleep deprivation (RSD; for 24 hour). Pain...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0172009/AIM.006
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Patients with chronic kidney disease (CKD) have specific dietary needs due to recommended dietary restrictions. However, there is no specific index for evaluating the quality of diet in patients with CKD. OBJECTIVE: To define and compare three specific diet quality indices in patients with CKD. METHODS:Tw...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:This study ascertained the effects of soy, in the forms of textured soy protein (TSP) and soy nuts, on lipid profiles, apolipoproteins, inflammatory and prothrombotic markers, and blood pressure in elderly women diagnosed with metabolic syndrome (MetS). METHODS:This was a 12-week parallel, randomized, contr...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,随机对照试验
doi:012158/AIM.004
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:HIV infection affects all body organs including kidney. Since the frequency of HIV-related renal disorders is unknown in Iran and the number of HIV-infected patients is increasing, this study was conducted for the first time in Iran to assess the frequency of electrolyte imbalance, renal failure, and protein...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:07103/AIM.0010
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Alzheimer and Parkinson diseases (AD and PD) are the two most important neurodegenerative disorders. This paper aims to determine the possible molecular linkage between these two common neurodegenerative diseases by a combination of computational investigations. METHODS:According to our aim, common sets of ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0161902/AIM.007
更新日期:2016-02-01 00:00:00
abstract::Evans syndrome is a rare syndrome associated with the simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and idiopathic thrombocytopenic purpura (ITP). Furthermore, acute kidney injury (AKI) is a syndrome characterized by the rapid loss of kidney excretory function and is most often secondary...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2019-06-01 00:00:00