A model of ionic transport and osmotic volume control in cochlear outer hair cells.

abstract：:How did people in the sixteenth and seventeenth centuries account for sleep loss? This article answers this question through an in-depth analysis of the life-writings of six early modern women and men that suffered from periodic or persistent episodes of sleep loss. It focuses on the ways in which these health crises ...

journal_title：Interface focus

authors： Handley S

更新日期：2020-06-06 00:00:00

abstract：:Chemoattractant gradients are usually considered in terms of sources and sinks that are independent of the chemotactic cell. However, recent interest has focused on 'self-generated' gradients, in which cell populations create their own local gradients as they move. Here, we consider the interplay between chemoattracta...

journal_title：Interface focus

authors： Mackenzie JA,Nolan M,Insall RH

更新日期：2016-10-06 00:00:00

abstract：:Dynamic remodelling of actin stress fibres (SFs) allows non-muscle cells to adapt to applied forces such as uniaxial cell shortening. However, the mechanism underlying rapid and selective disassembly of SFs oriented in the direction of shortening remains to be elucidated. Here, we investigated how myosin crossbridge c...

journal_title：Interface focus

authors： Matsui TS,Kaunas R,Kanzaki M,Sato M,Deguchi S

更新日期：2011-10-06 00:00:00

abstract：:Owls are an order of birds of prey that are known for the development of a silent flight. We review here the morphological adaptations of owls leading to silent flight and discuss also aerodynamic properties of owl wings. We start with early observations (until 2005), and then turn to recent advances. The large wings ...

journal_title：Interface focus

authors： Wagner H,Weger M,Klaas M,Schröder W

更新日期：2017-02-06 00:00:00

abstract：:Multi-site enzymes, defined as where multiple substrate molecules can bind simultaneously to the same enzyme molecule, play a key role in a number of biological networks, with the Escherichia coli protease ClpXP a well-studied example. These enzymes can form a low latency 'waiting line' of substrate to the enzyme's ca...

journal_title：Interface focus

authors： Hochendoner P,Ogle C,Mather WH

更新日期：2014-06-06 00:00:00

abstract：:This paper proposes methods and technologies that advance the state of the art for modelling the musculoskeletal system across the spatial and temporal scales; and storing these using efficient ontologies and tools. We present population-based modelling as an efficient method to rapidly generate individual morphology ...

journal_title：Interface focus

authors： Fernandez J,Zhang J,Heidlauf T,Sartori M,Besier T,Röhrle O,Lloyd D

更新日期：2016-04-06 00:00:00

abstract：:The development of bioadhesives inspired from marine animals is a promising approach to generate new tissue-compatible medical components. A number of marine species, through their adhesive properties, also represent significant foulers that become increasingly problematic to aquaculture, shipping or local biodiversit...

journal_title：Interface focus

authors： Pennati R,Rothbächer U

更新日期：2015-02-06 00:00:00

abstract：:Nanoparticles do not exist in thermodynamical equilibrium because of high surface free energy, thus they have only kinetic stability. Spontaneous changes can be delayed by designed surface coating. In biomedical applications, superparamagnetic iron oxide nanoparticles (SPIONs) require an optimized coating in order to ...

journal_title：Interface focus

authors： Tombácz E,Farkas K,Földesi I,Szekeres M,Illés E,Tóth IY,Nesztor D,Szabó T

更新日期：2016-12-06 00:00:00

abstract：:'Managed grazing' is gaining attention for its potential to contribute to climate change mitigation by reducing bare ground and promoting perennialization, thereby enhancing soil carbon sequestration (SCS). Understanding why ranchers adopt managed grazing is key to developing the right incentives. In this paper, we ex...

journal_title：Interface focus

authors： Gosnell H,Charnley S,Stanley P

更新日期：2020-10-06 00:00:00

abstract：:In recent years, far from arguing that evolutionary approaches to our own species permit us to describe the fundamental character of human nature, a prominent group of cultural evolutionary theorists has instead argued that the very idea of 'human nature' is one we should reject. It makes no sense, they argue, to spea...

journal_title：Interface focus

authors： Lewens T

更新日期：2017-10-06 00:00:00

abstract：:Biofuels production from microalgae attracts much attention but remains an unproven technology. We explore routes to enhance production through modifications to a range of generic microalgal physiological characteristics. Our analysis shows that biofuels production may be enhanced ca fivefold through genetic modificat...

journal_title：Interface focus

authors： Flynn KJ,Mitra A,Greenwell HC,Sui J

更新日期：2013-02-06 00:00:00

abstract：:Biominerals are typically indispensable structures for their host organism in which they serve varying functions, such as mechanical support and protection, mineral storage, detoxification site, or as a sensor or optical guide. In this perspective article, we highlight the occurrence of both structural diversity and u...

journal_title：Interface focus

authors： Harris J,Böhm CF,Wolf SE

更新日期：2017-08-06 00:00:00

abstract：:We present the development of a tool, which provides users with the ability to visualize and interact with a comprehensive description of a multi-scale model of the renal nephron. A one-dimensional anatomical model of the nephron has been created and is used for visualization and modelling of tubule transport in vario...

journal_title：Interface focus

authors： Nickerson DP,Terkildsen JR,Hamilton KL,Hunter PJ

更新日期：2011-06-06 00:00:00

abstract：:Must higher level biological processes always be derivable from lower level data and mechanisms, as assumed by the idea that an organism is completely defined by its genome? Or are higher level properties necessarily also causes of lower level behaviour, involving actions and interactions both ways? This article uses ...

journal_title：Interface focus

authors： Noble D

更新日期：2012-02-06 00:00:00

abstract：:Apart from interacting, prey and predators may also avoid each other by moving into refuges where they lack food, yet survive by switching to an energy-saving physiological state. Lotka-Volterra models of predator-prey interactions ignore this option. Therefore, we have modelled this game of 'joining versus opting out...

journal_title：Interface focus

authors： Staňková K,Abate A,Sabelis MW,Buša J,You L

更新日期：2013-12-06 00:00:00

abstract：:A numerical model for orthogonal cutting using the material point method was applied to woodcutting using a bench plane. The cutting process was modelled by accounting for surface energy associated with wood fracture toughness for crack growth parallel to the grain. By using damping to deal with dynamic crack propagat...

journal_title：Interface focus

authors： Nairn JA

更新日期：2016-06-06 00:00:00

abstract：:In this paper, we show that solutions to ordinary differential equations describing the large-population limits of Markovian stochastic epidemic models can be interpreted as survival or cumulative hazard functions when analysing data on individuals sampled from the population. We refer to the individual-level survival...

journal_title：Interface focus

authors： KhudaBukhsh WR,Choi B,Kenah E,Rempała GA

更新日期：2020-02-06 00:00:00

abstract：:The morphology of the toe epithelium of the rock frog, Staurois parvus (Family Ranidae), was investigated using a variety of microscopical techniques. The toe pad epithelium is stratified (four to five cell layers), the apical parts of the cells of the outermost layer being separated by fluid-filled channels. The surf...

journal_title：Interface focus

authors： Drotlef DM,Appel E,Peisker H,Dening K,Del Campo A,Gorb SN,Barnes WJ

更新日期：2015-02-06 00:00:00

abstract：:Periodontitis is a polymicrobial, biofilm-caused, inflammatory disease affecting the tooth-supporting tissues. It is not only the leading cause of tooth loss worldwide, but can also impact systemic health. The development of effective treatment strategies is hampered by the complicated disease pathogenesis which is be...

journal_title：Interface focus

authors： Bloch S,Tomek MB,Friedrich V,Messner P,Schäffer C

更新日期：2019-04-06 00:00:00

abstract：:Ultrasound elastography is a technique used for clinical imaging of tissue stiffness with a conventional ultrasound machine. It was first proposed two decades ago, but active research continues in this area to the present day. Numerous clinical applications have been investigated, mostly related to cancer imaging, and...

journal_title：Interface focus

authors： Treece G,Lindop J,Chen L,Housden J,Prager R,Gee A

更新日期：2011-08-06 00:00:00

abstract：:Formation of spatial patterns of cells is a recurring theme in biology and often depends on regulated cell motility. Motility of the rod-shaped cells of the bacterium Myxococcus xanthus depends on two motility machineries, type IV pili (giving rise to S-motility) and the gliding motility apparatus (giving rise to A-mo...

journal_title：Interface focus

authors： Starruß J,Peruani F,Jakovljevic V,Søgaard-Andersen L,Deutsch A,Bär M

更新日期：2012-12-06 00:00:00

abstract：:Material deformation and pitting from cavitation bubble collapse is investigated using fluid and material dynamics and their interaction. In the fluid, a novel hybrid approach, which links a boundary element method and a compressible finite difference method, is used to capture non-spherical bubble dynamics and result...

journal_title：Interface focus

authors： Chahine GL,Hsiao CT

更新日期：2015-10-06 00:00:00

abstract：:Biological variety and major evolutionary transitions suggest that the space of possible morphologies may have varied among lineages and through time. However, most models of phylogenetic character evolution assume that the potential state space is finite. Here, I explore what the morphological state space might be li...

journal_title：Interface focus

authors： Hoyal Cuthill JF

更新日期：2015-12-06 00:00:00

abstract：:We propose that fungi Basidiomycetes can be used as computing devices: information is represented by spikes of electrical activity, a computation is implemented in a mycelium network and an interface is realized via fruit bodies. In a series of scoping experiments, we demonstrate that electrical activity recorded on f...

journal_title：Interface focus

authors： Adamatzky A

更新日期：2018-12-06 00:00:00

abstract：:Organisms modify and choose components of their local environments. This 'niche construction' can alter ecological processes, modify natural selection and contribute to inheritance through ecological legacies. Here, we propose that niche construction initiates and modifies the selection directly affecting the construc...

journal_title：Interface focus

authors： Laland K,Odling-Smee J,Endler J

更新日期：2017-10-06 00:00:00

abstract：:This article uses an integrative systems biological view of the relationship between genotypes and phenotypes to clarify some conceptual problems in biological debates about causality. The differential (gene-centric) view is incomplete in a sense analogous to using differentiation without integration in mathematics. D...

journal_title：Interface focus

authors： Noble D

更新日期：2011-02-06 00:00:00

abstract：:The placenta provides all the nutrients required for the fetus through pregnancy. It develops dynamically, and, to avoid rejection of the fetus, there is no mixing of fetal and maternal blood; rather, the branched placental villi 'bathe' in blood supplied from the uterine arteries. Within the villi, the feto-placental...

journal_title：Interface focus

authors： Clark AR,Lin M,Tawhai M,Saghian R,James JL

更新日期：2015-04-06 00:00:00

abstract：:Yves Bouligand's analysis of the organizations of biological materials in relation to those of liquid crystals enabled the development of the idea that physical forces exerting their actions under strong spatial constraints determine the structures and morphologies of these materials. The different levels of organizat...

journal_title：Interface focus

authors： Charvolin J,Sadoc JF

更新日期：2012-10-06 00:00:00

abstract：:Despite there being many studies that have evaluated breast implant rupture, there is no consensus about causes and incidence. Most studies lack a multifactorial analysis of what causes breast implants to rupture. To fill this gap, an experimental protocol was developed to compare ruptured and intact Poly Implant Prot...

journal_title：Interface focus

authors： Ramião NG,Martins PS,Barroso ML,Santos DC,Fernandes AA

更新日期：2019-08-06 00:00:00

abstract：:A novel class of ultra-thin fibres, which affect microbial growth, were explored. The microbial properties of poly(methyl methacrylate) fibres containing 2, 4 and 8 wt% of graphene nanoplatelets (GNPs) were studied. GNPs were dispersed in a polymeric solution and processed using pressurized gyration. Electron microsco...

journal_title：Interface focus

authors： Matharu RK,Porwal H,Ciric L,Edirisinghe M

更新日期：2018-06-06 00:00:00