About collagen, a tribute to Yves Bouligand.

abstract：:Chemoattractant gradients are usually considered in terms of sources and sinks that are independent of the chemotactic cell. However, recent interest has focused on 'self-generated' gradients, in which cell populations create their own local gradients as they move. Here, we consider the interplay between chemoattracta...

journal_title：Interface focus

authors： Mackenzie JA,Nolan M,Insall RH

更新日期：2016-10-06 00:00:00

abstract：:Clinicians face many challenges when diagnosing and treating breast cancer. These challenges include interpreting and co-locating information between different medical imaging modalities that are used to identify tumours and predicting where these tumours move to during different treatment procedures. We have develope...

journal_title：Interface focus

authors： Babarenda Gamage TP,Malcolm DTK,Maso Talou G,Mîra A,Doyle A,Nielsen PMF,Nash MP

更新日期：2019-08-06 00:00:00

abstract：:Dynamic remodelling of actin stress fibres (SFs) allows non-muscle cells to adapt to applied forces such as uniaxial cell shortening. However, the mechanism underlying rapid and selective disassembly of SFs oriented in the direction of shortening remains to be elucidated. Here, we investigated how myosin crossbridge c...

journal_title：Interface focus

authors： Matsui TS,Kaunas R,Kanzaki M,Sato M,Deguchi S

更新日期：2011-10-06 00:00:00

abstract：:Must higher level biological processes always be derivable from lower level data and mechanisms, as assumed by the idea that an organism is completely defined by its genome? Or are higher level properties necessarily also causes of lower level behaviour, involving actions and interactions both ways? This article uses ...

journal_title：Interface focus

authors： Noble D

更新日期：2012-02-06 00:00:00

abstract：:Mental time travel allows us to revisit our memories and imagine future scenarios, and this is why memories are not only about the past, but they are also prospective. These episodic memories are not a fixed store of what happened, however, they are reassessed each time they are revisited and depend on the sequence in...

journal_title：Interface focus

authors： Clayton N,Wilkins C

更新日期：2017-06-06 00:00:00

abstract：:Noble metal nanoparticles (NPs) show distinctive plasmonic optical properties and superior photostability, enabling them to serve as photostable multi-coloured optical molecular probes and sensors for real-time in vivo imaging. To effectively study biological functions in vivo, it is essential that the NP probes are b...

journal_title：Interface focus

authors： Browning LM,Huang T,Xu XH

更新日期：2013-06-06 00:00:00

abstract：:Most ecological interactions occur in environments that are spatially and temporally heterogeneous-'patchy'-across a wide range of scales. In contrast, most theoretical models of ecological interactions, especially large-scale models applied to societal issues such as climate change, resource management and human heal...

journal_title：Interface focus

authors： Grünbaum D

更新日期：2012-04-06 00:00:00

abstract：:The morphology of the toe epithelium of the rock frog, Staurois parvus (Family Ranidae), was investigated using a variety of microscopical techniques. The toe pad epithelium is stratified (four to five cell layers), the apical parts of the cells of the outermost layer being separated by fluid-filled channels. The surf...

journal_title：Interface focus

authors： Drotlef DM,Appel E,Peisker H,Dening K,Del Campo A,Gorb SN,Barnes WJ

更新日期：2015-02-06 00:00:00

abstract：:In recent years, there has been a move away from the use of static in vitro two-dimensional cell culture models for testing the chemical safety and efficacy of drugs. Such models are increasingly being replaced by more physiologically relevant cell culture systems featuring dynamic flow and/or three-dimensional struct...

journal_title：Interface focus

authors： Hyndman L,McKee S,Mottram NJ,Singh B,Webb SD,McGinty S

更新日期：2020-04-06 00:00:00

abstract：:A computational model of the outer hair cell (OHC) of the mammalian cochlea is presented. It addresses the way in which movement of ions controls the cell shape and regulates pH. The model takes into account the possible chloride-bicarbonate exchange function of prestin, a protein highly expressed in the plasma membra...

journal_title：Interface focus

authors： West T,Ashmore J

更新日期：2014-12-06 00:00:00

abstract：:We propose that fungi Basidiomycetes can be used as computing devices: information is represented by spikes of electrical activity, a computation is implemented in a mycelium network and an interface is realized via fruit bodies. In a series of scoping experiments, we demonstrate that electrical activity recorded on f...

journal_title：Interface focus

authors： Adamatzky A

更新日期：2018-12-06 00:00:00

abstract：:Pentameric ligand-gated ion channels (pLGICs) are an important class of widely expressed membrane neuroreceptors, which play a crucial role in fast synaptic communications and are involved in several neurological conditions. They are activated by the binding of neurotransmitters, which trigger the transmission of an e...

journal_title：Interface focus

authors： Crnjar A,Comitani F,Melis C,Molteni C

更新日期：2019-06-06 00:00:00

abstract：:The development of bioadhesives inspired from marine animals is a promising approach to generate new tissue-compatible medical components. A number of marine species, through their adhesive properties, also represent significant foulers that become increasingly problematic to aquaculture, shipping or local biodiversit...

journal_title：Interface focus

authors： Pennati R,Rothbächer U

更新日期：2015-02-06 00:00:00

abstract：:'Managed grazing' is gaining attention for its potential to contribute to climate change mitigation by reducing bare ground and promoting perennialization, thereby enhancing soil carbon sequestration (SCS). Understanding why ranchers adopt managed grazing is key to developing the right incentives. In this paper, we ex...

journal_title：Interface focus

authors： Gosnell H,Charnley S,Stanley P

更新日期：2020-10-06 00:00:00

abstract：:This article uses an integrative systems biological view of the relationship between genotypes and phenotypes to clarify some conceptual problems in biological debates about causality. The differential (gene-centric) view is incomplete in a sense analogous to using differentiation without integration in mathematics. D...

journal_title：Interface focus

authors： Noble D

更新日期：2011-02-06 00:00:00

abstract：:We present the development of a tool, which provides users with the ability to visualize and interact with a comprehensive description of a multi-scale model of the renal nephron. A one-dimensional anatomical model of the nephron has been created and is used for visualization and modelling of tubule transport in vario...

journal_title：Interface focus

authors： Nickerson DP,Terkildsen JR,Hamilton KL,Hunter PJ

更新日期：2011-06-06 00:00:00

abstract：:Moving from homogeneous water-splitting photocatalytic systems to photoelectrochemical devices requires the preparation and evaluation of novel p-type transparent conductive photoelectrode substrates. We report here on the sensitization of polystyrene-block-poly-(2-vinylpyridine) (PS-b-P2VP) diblock copolymer-template...

journal_title：Interface focus

authors： Massin J,Bräutigam M,Kaeffer N,Queyriaux N,Field MJ,Schacher FH,Popp J,Chavarot-Kerlidou M,Dietzek B,Artero V

更新日期：2015-06-06 00:00:00

abstract：:The emergence of life on Earth (and elsewhere) must have occurred in a milieu that is far from equilibrium, such as at alkaline hydrothermal vents that would have harboured built-in gradients in temperature, redox potential and pH along with precipitated iron-bearing minerals capable of separating these gradients, con...

journal_title：Interface focus

authors： Ponce A

更新日期：2019-12-06 00:00:00

abstract：:Biofuels production from microalgae attracts much attention but remains an unproven technology. We explore routes to enhance production through modifications to a range of generic microalgal physiological characteristics. Our analysis shows that biofuels production may be enhanced ca fivefold through genetic modificat...

journal_title：Interface focus

authors： Flynn KJ,Mitra A,Greenwell HC,Sui J

更新日期：2013-02-06 00:00:00

abstract：:Ultrasound elastography is a technique used for clinical imaging of tissue stiffness with a conventional ultrasound machine. It was first proposed two decades ago, but active research continues in this area to the present day. Numerous clinical applications have been investigated, mostly related to cancer imaging, and...

journal_title：Interface focus

authors： Treece G,Lindop J,Chen L,Housden J,Prager R,Gee A

更新日期：2011-08-06 00:00:00

abstract：:The scattering strength of a random medium relies on the geometry and spatial distribution of its components as well as on their refractive index. Anisotropy can, therefore, play a major role in the optimization of the scattering efficiency in both biological and synthetic materials. In this study, we show that, by ex...

journal_title：Interface focus

authors： Jacucci G,Onelli OD,De Luca A,Bertolotti J,Sapienza R,Vignolini S

更新日期：2019-02-06 00:00:00

abstract：:Cell migration participates in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. The cells specifically migrate to destiny sites induced by the gradually varying conce...

journal_title：Interface focus

authors： Wu J,Mao Z,Tan H,Han L,Ren T,Gao C

更新日期：2012-06-06 00:00:00

abstract：:Biominerals are typically indispensable structures for their host organism in which they serve varying functions, such as mechanical support and protection, mineral storage, detoxification site, or as a sensor or optical guide. In this perspective article, we highlight the occurrence of both structural diversity and u...

journal_title：Interface focus

authors： Harris J,Böhm CF,Wolf SE

更新日期：2017-08-06 00:00:00

abstract：:Periodontitis is a polymicrobial, biofilm-caused, inflammatory disease affecting the tooth-supporting tissues. It is not only the leading cause of tooth loss worldwide, but can also impact systemic health. The development of effective treatment strategies is hampered by the complicated disease pathogenesis which is be...

journal_title：Interface focus

authors： Bloch S,Tomek MB,Friedrich V,Messner P,Schäffer C

更新日期：2019-04-06 00:00:00

abstract：:[This corrects the article DOI: 10.1098/rsfs.2018.0034.]. ...

journal_title：Interface focus

authors： van Delft FCMJM,Ipolitti G,Nicolau DV Jr,Sudalaiyadum Perumal A,Kašpar O,Kheireddine S,Wachsmann-Hogiu S,Nicolau DV

更新日期：2019-10-06 00:00:00

abstract：:Pancreatic β-cells use Ca(2+)-dependent exocytosis of large dense core vesicles to release insulin. Exocytosis in β-cells has been studied biochemically, biophysically and optically. We have previously developed a biophysical method to monitor release of endogenous intragranular constituents that are co-released with ...

journal_title：Interface focus

authors： Galvanovskis J,Braun M,Rorsman P

更新日期：2011-02-06 00:00:00

abstract：:The ability of the baby to receive nutrients and oxygen in utero depends on the healthy development of the placenta. For maternal blood to adequately perfuse the placenta, it dramatically alters the arteries in the uterus that supply it with nutrient-rich blood right from the start of pregnancy. Placental cells (troph...

journal_title：Interface focus

authors： Saghian R,Bogle G,James JL,Clark AR

更新日期：2019-10-06 00:00:00

abstract：:Organisms modify and choose components of their local environments. This 'niche construction' can alter ecological processes, modify natural selection and contribute to inheritance through ecological legacies. Here, we propose that niche construction initiates and modifies the selection directly affecting the construc...

journal_title：Interface focus

authors： Laland K,Odling-Smee J,Endler J

更新日期：2017-10-06 00:00:00

abstract：:Despite there being many studies that have evaluated breast implant rupture, there is no consensus about causes and incidence. Most studies lack a multifactorial analysis of what causes breast implants to rupture. To fill this gap, an experimental protocol was developed to compare ruptured and intact Poly Implant Prot...

journal_title：Interface focus

authors： Ramião NG,Martins PS,Barroso ML,Santos DC,Fernandes AA

更新日期：2019-08-06 00:00:00

abstract：:Nanoparticles do not exist in thermodynamical equilibrium because of high surface free energy, thus they have only kinetic stability. Spontaneous changes can be delayed by designed surface coating. In biomedical applications, superparamagnetic iron oxide nanoparticles (SPIONs) require an optimized coating in order to ...

journal_title：Interface focus

authors： Tombácz E,Farkas K,Földesi I,Szekeres M,Illés E,Tóth IY,Nesztor D,Szabó T

更新日期：2016-12-06 00:00:00