A queueing approach to multi-site enzyme kinetics.

abstract：:We investigate, by molecular dynamics simulation, the behaviour of discotic particles in a solvent of Lennard-Jones spheres. When chromonic disc-sphere interactions are imposed on these systems, three regimes of self-assembly are observed. At moderate temperatures, numerous short threads of discs develop, but these th...

journal_title：Interface focus

authors： Prybytak P,Frith WJ,Cleaver DJ

更新日期：2012-10-06 00:00:00

abstract：:Pentameric ligand-gated ion channels (pLGICs) are an important class of widely expressed membrane neuroreceptors, which play a crucial role in fast synaptic communications and are involved in several neurological conditions. They are activated by the binding of neurotransmitters, which trigger the transmission of an e...

journal_title：Interface focus

authors： Crnjar A,Comitani F,Melis C,Molteni C

更新日期：2019-06-06 00:00:00

abstract：:A novel class of ultra-thin fibres, which affect microbial growth, were explored. The microbial properties of poly(methyl methacrylate) fibres containing 2, 4 and 8 wt% of graphene nanoplatelets (GNPs) were studied. GNPs were dispersed in a polymeric solution and processed using pressurized gyration. Electron microsco...

journal_title：Interface focus

authors： Matharu RK,Porwal H,Ciric L,Edirisinghe M

更新日期：2018-06-06 00:00:00

abstract：:The morphology of the toe epithelium of the rock frog, Staurois parvus (Family Ranidae), was investigated using a variety of microscopical techniques. The toe pad epithelium is stratified (four to five cell layers), the apical parts of the cells of the outermost layer being separated by fluid-filled channels. The surf...

journal_title：Interface focus

authors： Drotlef DM,Appel E,Peisker H,Dening K,Del Campo A,Gorb SN,Barnes WJ

更新日期：2015-02-06 00:00:00

abstract：:In recent years, there has been a move away from the use of static in vitro two-dimensional cell culture models for testing the chemical safety and efficacy of drugs. Such models are increasingly being replaced by more physiologically relevant cell culture systems featuring dynamic flow and/or three-dimensional struct...

journal_title：Interface focus

authors： Hyndman L,McKee S,Mottram NJ,Singh B,Webb SD,McGinty S

更新日期：2020-04-06 00:00:00

abstract：:'Managed grazing' is gaining attention for its potential to contribute to climate change mitigation by reducing bare ground and promoting perennialization, thereby enhancing soil carbon sequestration (SCS). Understanding why ranchers adopt managed grazing is key to developing the right incentives. In this paper, we ex...

journal_title：Interface focus

authors： Gosnell H,Charnley S,Stanley P

更新日期：2020-10-06 00:00:00

abstract：:The scattering strength of a random medium relies on the geometry and spatial distribution of its components as well as on their refractive index. Anisotropy can, therefore, play a major role in the optimization of the scattering efficiency in both biological and synthetic materials. In this study, we show that, by ex...

journal_title：Interface focus

authors： Jacucci G,Onelli OD,De Luca A,Bertolotti J,Sapienza R,Vignolini S

更新日期：2019-02-06 00:00:00

abstract：:The development of bioadhesives inspired from marine animals is a promising approach to generate new tissue-compatible medical components. A number of marine species, through their adhesive properties, also represent significant foulers that become increasingly problematic to aquaculture, shipping or local biodiversit...

journal_title：Interface focus

authors： Pennati R,Rothbächer U

更新日期：2015-02-06 00:00:00

abstract：:We propose that fungi Basidiomycetes can be used as computing devices: information is represented by spikes of electrical activity, a computation is implemented in a mycelium network and an interface is realized via fruit bodies. In a series of scoping experiments, we demonstrate that electrical activity recorded on f...

journal_title：Interface focus

authors： Adamatzky A

更新日期：2018-12-06 00:00:00

abstract：:Yves Bouligand's analysis of the organizations of biological materials in relation to those of liquid crystals enabled the development of the idea that physical forces exerting their actions under strong spatial constraints determine the structures and morphologies of these materials. The different levels of organizat...

journal_title：Interface focus

authors： Charvolin J,Sadoc JF

更新日期：2012-10-06 00:00:00

abstract：:We investigate a model of hard pear-shaped particles which forms the bicontinuous Ia[Formula: see text]d structure by entropic self-assembly, extending the previous observations of Barmes et al. (2003 Phys. Rev. E68, 021708. (doi:10.1103/PhysRevE.68.021708)) and Ellison et al. (2006 Phys. Rev. Lett.97, 237801. (doi:10...

journal_title：Interface focus

authors： Schönhöfer PWA,Ellison LJ,Marechal M,Cleaver DJ,Schröder-Turk GE

更新日期：2017-08-06 00:00:00

abstract：:One of the predictions of game theory is that cooperative behaviours are vulnerable to exploitation by selfish individuals, but this result seemingly contradicts the survival of cooperation observed in nature. In this review, we will introduce game theoretical concepts that lead to this conclusion and show how the spa...

journal_title：Interface focus

authors： Lambert G,Vyawahare S,Austin RH

更新日期：2014-08-06 00:00:00

abstract：:Apart from interacting, prey and predators may also avoid each other by moving into refuges where they lack food, yet survive by switching to an energy-saving physiological state. Lotka-Volterra models of predator-prey interactions ignore this option. Therefore, we have modelled this game of 'joining versus opting out...

journal_title：Interface focus

authors： Staňková K,Abate A,Sabelis MW,Buša J,You L

更新日期：2013-12-06 00:00:00

abstract：:Must higher level biological processes always be derivable from lower level data and mechanisms, as assumed by the idea that an organism is completely defined by its genome? Or are higher level properties necessarily also causes of lower level behaviour, involving actions and interactions both ways? This article uses ...

journal_title：Interface focus

authors： Noble D

更新日期：2012-02-06 00:00:00

abstract：:Chemoattractant gradients are usually considered in terms of sources and sinks that are independent of the chemotactic cell. However, recent interest has focused on 'self-generated' gradients, in which cell populations create their own local gradients as they move. Here, we consider the interplay between chemoattracta...

journal_title：Interface focus

authors： Mackenzie JA,Nolan M,Insall RH

更新日期：2016-10-06 00:00:00

abstract：:A numerical model for orthogonal cutting using the material point method was applied to woodcutting using a bench plane. The cutting process was modelled by accounting for surface energy associated with wood fracture toughness for crack growth parallel to the grain. By using damping to deal with dynamic crack propagat...

journal_title：Interface focus

authors： Nairn JA

更新日期：2016-06-06 00:00:00

abstract：:Ultrasound elastography is a technique used for clinical imaging of tissue stiffness with a conventional ultrasound machine. It was first proposed two decades ago, but active research continues in this area to the present day. Numerous clinical applications have been investigated, mostly related to cancer imaging, and...

journal_title：Interface focus

authors： Treece G,Lindop J,Chen L,Housden J,Prager R,Gee A

更新日期：2011-08-06 00:00:00

abstract：:Organisms modify and choose components of their local environments. This 'niche construction' can alter ecological processes, modify natural selection and contribute to inheritance through ecological legacies. Here, we propose that niche construction initiates and modifies the selection directly affecting the construc...

journal_title：Interface focus

authors： Laland K,Odling-Smee J,Endler J

更新日期：2017-10-06 00:00:00

abstract：:Periodontitis is a polymicrobial, biofilm-caused, inflammatory disease affecting the tooth-supporting tissues. It is not only the leading cause of tooth loss worldwide, but can also impact systemic health. The development of effective treatment strategies is hampered by the complicated disease pathogenesis which is be...

journal_title：Interface focus

authors： Bloch S,Tomek MB,Friedrich V,Messner P,Schäffer C

更新日期：2019-04-06 00:00:00

abstract：:[This corrects the article DOI: 10.1098/rsfs.2018.0034.]. ...

journal_title：Interface focus

authors： van Delft FCMJM,Ipolitti G,Nicolau DV Jr,Sudalaiyadum Perumal A,Kašpar O,Kheireddine S,Wachsmann-Hogiu S,Nicolau DV

更新日期：2019-10-06 00:00:00

abstract：:Recent advances in design, sensing and control have led to aerial robots that offer great promise in a range of real-world applications. However, one critical open question centres on how to improve the energetic efficiency of aerial robots so that they can be useful in practical situations. This review paper provides...

journal_title：Interface focus

authors： Karydis K,Kumar V

更新日期：2017-02-06 00:00:00

abstract：:The combination of high strength and high toughness is a desirable feature that structural materials should display. However, while in the past, engineers had to compromise on either strength or toughness depending on the requested application, nowadays, new toughening strategies are available to provide strong materi...

journal_title：Interface focus

authors： Berardo A,Pantano MF,Pugno NM

更新日期：2016-02-06 00:00:00

abstract：:Books with titles like 'The Call of the Wild' seemed to set a path for a life. Thus, I would be an explorer-a plan that did not work out so well, at least at first. On leaving school I got a job as a 'Works Chemist Improver', testing Ni catalysts for the hydrogenation of phenol to cyclohexanol. Taking night classes I ...

journal_title：Interface focus

authors： Russell MJ

更新日期：2019-12-06 00:00:00

abstract：:Material deformation and pitting from cavitation bubble collapse is investigated using fluid and material dynamics and their interaction. In the fluid, a novel hybrid approach, which links a boundary element method and a compressible finite difference method, is used to capture non-spherical bubble dynamics and result...

journal_title：Interface focus

authors： Chahine GL,Hsiao CT

更新日期：2015-10-06 00:00:00

abstract：:Eukaryogenesis-the process by which the eukaryotic cell emerged-has long puzzled scientists. It has been assumed that the fossil record has little to say about this process, in part because important characters such as the nucleus and mitochondria are rarely preserved, and in part because the prevailing model of early...

journal_title：Interface focus

authors： Porter SM

更新日期：2020-08-06 00:00:00

abstract：:This article uses an integrative systems biological view of the relationship between genotypes and phenotypes to clarify some conceptual problems in biological debates about causality. The differential (gene-centric) view is incomplete in a sense analogous to using differentiation without integration in mathematics. D...

journal_title：Interface focus

authors： Noble D

更新日期：2011-02-06 00:00:00

abstract：:Blood glucose levels are controlled by well-known physiological feedback loops: high glucose levels promote insulin release from the pancreas, which in turn stimulates cellular glucose uptake. Low blood glucose levels promote pancreatic glucagon release, stimulating glycogen breakdown to glucose in the liver. In healt...

journal_title：Interface focus

authors： Csete M,Doyle J

更新日期：2014-10-06 00:00:00

abstract：:Most ecological interactions occur in environments that are spatially and temporally heterogeneous-'patchy'-across a wide range of scales. In contrast, most theoretical models of ecological interactions, especially large-scale models applied to societal issues such as climate change, resource management and human heal...

journal_title：Interface focus

authors： Grünbaum D

更新日期：2012-04-06 00:00:00

abstract：:A computational model of the outer hair cell (OHC) of the mammalian cochlea is presented. It addresses the way in which movement of ions controls the cell shape and regulates pH. The model takes into account the possible chloride-bicarbonate exchange function of prestin, a protein highly expressed in the plasma membra...

journal_title：Interface focus

authors： West T,Ashmore J

更新日期：2014-12-06 00:00:00

abstract：:Clinicians face many challenges when diagnosing and treating breast cancer. These challenges include interpreting and co-locating information between different medical imaging modalities that are used to identify tumours and predicting where these tumours move to during different treatment procedures. We have develope...

journal_title：Interface focus

authors： Babarenda Gamage TP,Malcolm DTK,Maso Talou G,Mîra A,Doyle A,Nielsen PMF,Nash MP

更新日期：2019-08-06 00:00:00