Abstract:
BACKGROUND:Depression in late life is a risk factor for cognitive decline. Depression is also associated with increased disability and social support deficits; these may precede conversion to dementia and inform risk. In this study, we examined if baseline or one-year change in disability and social support predicted later cognitive deterioration. METHODS:299 cognitively intact depressed older adults were followed for an average of approximately seven years. Participants received antidepressant treatment according to a standardized algorithm. Neuropsychological testing and assessment of disability and social support were assessed annually. Cognitive diagnosis was reviewed annually at a consensus conference to determine if participants remained cognitively normal, or if they progressed to either dementia or cognitively impaired, no dementia (CIND). RESULTS:During study participation, 167 individuals remained cognitively normal (56%), 83 progressed to CIND (28%), and 49 progressed to dementia (16%). Greater baseline instrumental activities of daily living (IADL) deficits predicted subsequent conversion to a cognitive diagnosis (CIND or dementia). However, neither baseline measures nor one-year change in basic ADLs (BADLs) and social support predicted cognitive conversion. In post hoc analyses, two IADL measures (managing finances, preparing meals) significantly increased the odds of cognitive conversion. CONCLUSIONS:Greater IADL deficits predicted increased risk of cognitive conversion. Assessment of IADL deficits may provide clues about risk of later cognitive decline.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Riddle M,McQuoid DR,Potter GG,Steffens DC,Taylor WDdoi
10.1017/S1041610214002543subject
Has Abstractpub_date
2015-05-01 00:00:00pages
707-14issue
5eissn
1041-6102issn
1741-203Xpii
S1041610214002543journal_volume
27pub_type
杂志文章abstract:BACKGROUND:Young-onset dementia (YOD) is defined as dementia that develops before the age of 65 years. The prevalence and type of neuropsychiatric symptoms (NPS) in YOD differ from patients with late onset dementia. NPS in dementia patients are often treated with psychotropic drugs. The aim of this study was to investi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213002330
更新日期:2014-12-01 00:00:00
abstract:UNLABELLED:This article reports the findings of a 3-year epidemiological survey for dementia in an urban community-resident population in Mumbai (Bombay), India, wherein the prevalence of all types of dementia was determined. METHOD:The study was conducted in three stages. Stage 1: From a potential pool of 30,000 subj...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610201007852
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Clinical guidelines have the potential to assist in the management of aggression in dementia. This study aims to develop a conceptual framework for the construction of individualized guidelines for this group. METHODS:A concept map of the topic "How to manage aggression in dementia" was developed by reviewi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000014
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVES:People with dementia can face barriers when trying to access care after a diagnosis, particularly in young-onset dementia (YOD). Little is known about the effects of ethnicity on the use of anti-dementia medication and variations between age groups. The aim of this study was to analyze national data on varia...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220000794
更新日期:2020-06-02 00:00:00
abstract::ABSTRACTBackground:Delirium is a complex clinical syndrome characterized by disturbed consciousness, cognitive function, or perception and associated with serious adverse outcomes such as death, dementia, and the need for long-term care. However, recognition and management of delirium is poorly prioritized even though...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218001369
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVES:Geriatric depression complicates cognitive health in older adults. This study aims to investigate the impact of depressive symptoms on cognitive impairment in community-dwelling older adults, depending on whether cognitive dysfunction accompanied. DESIGN:A community-based longitudinal cohort study. SETTING...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220003622
更新日期:2020-11-16 00:00:00
abstract::Thirty-seven subjects, 15 with a clinical diagnosis of Alzheimer's disease and 22 normal controls, participated in a study of the accuracy of telephone screening in identifying potential dementia cases. The telephone protocol and scoring algorithm resulted in 100% sensitivity and 91% specificity. The findings suggest ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610295002171
更新日期:1995-10-01 00:00:00
abstract::The objectives of this randomized clinical trial were to investigate the impact of the discontinuation of long-term antipsychotics in residents with dementia in chronic care institutions and to identify clinical predictors of safe discontinuation. Subjects included 34 residents with dementia who were on antipsychotics...
journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s1041610202008396
更新日期:2002-06-01 00:00:00
abstract::Observed cognitive decline in the elderly has been widely reported in the literature. The relation of experimental cognitive ability measures to real-world cognitive competence has been questioned. This research examines the validity of English-language versions of two measures of everyday competency: the Memory in Re...
journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:1995-04-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217001612
更新日期:2018-01-01 00:00:00
abstract::This article discusses the role of some pathogenetical factors in the main morphological variants of vascular dementia and their correlation with certain clinical parameters. On the basis of computer-tomographical (CT) studies of 62 patients with dementia, it was possible to distinguish three groups of patients, accor...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610292001054
更新日期:1992-10-01 00:00:00
abstract::ABSTRACTObjectives:The objectives of the study were to examine the trajectory of spirituality among older adults, to investigate the roles of gender and religion on the developmental trajectory of spirituality, and to explore whether the linear growth of spirituality accelerated or decelerated at time points at which ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000029
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Although interpersonal interactions are thought to affect psychopathology in schizophrenia, there is a paucity of data about how older adults with schizophrenia manage interpersonal conflicts. This paper examines interpersonal conflict strategies and their impact on positive symptom remission in older adults...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212001093
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:A past history of self-harm is a significant risk factor for suicide in older people. The aims of this study are to (i) characterize older people who present with self-harm to emergency departments (EDs); and (ii) determine the predictors for repeat self-harm and suicide. METHODS:Demographic and clinical da...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217000308
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Music can be therapeutic to people with dementia; however, little is known about its effect on the family carers. This project aimed to (1) assess the effects of MP3 player use by a person with dementia on caregivers' mental health and wellbeing, including their self-care and health-promoting behavior and (2...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214001999
更新日期:2015-03-01 00:00:00
abstract::The dynamic processes and the way they interact in shaping a care system for demented patients are analyzed and discussed. The development of disability/dependency, interpreted in a simulation model based on Katz's index of ADL and Berger's scale "Rating the severity of senility," gave insight into the interplay of fo...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610296002888
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Despite the magnitude of dementia, little research on survival duration and prognosis of dementia has been reported in developing countries. This study was conducted to investigate survival times, identify related prognostic factors and construct a prognostic index (PI) for community-based dementia patients ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210000669
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Inability to walk compromises the well-being of the growing number of nursing home residents with dementia. The purpose of this study was to estimate the incidence and identify predictors of walking disability that may be remediable. METHODS:A cohort was followed fortnightly for a year in 15 nursing homes i...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610210000116
更新日期:2011-02-01 00:00:00
abstract::ABSTRACT Background: Mild cognitive impairment (MCI) is a diagnostic classification used to describe patients experiencing cognitive decline but without a corresponding impairment in daily functioning. Over the years, MCI diagnostic criteria have undergone major changes that correspond to advancements in research. Des...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214002270
更新日期:2014-11-05 00:00:00
abstract:BACKGROUND:A carer-held record (CHR) was developed to enable carers to contribute to care plans for their relatives with dementia, alongside other professionals. The aim of this study was to establish whether CHRs provide any measurable benefits for carers, in the areas of health, stress, knowledge of dementia and locu...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610205002565
更新日期:2006-06-01 00:00:00
abstract::ABSTRACTIntroduction:The relationship between Alzheimer's Disease (AD) and alcohol addiction is poorly characterized. Arrests for driving under the influence (DUI) can serve as a proxy for alcohol addiction. Therefore, the potential association between DUI and AD could be helpful in understanding the relationship betw...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218001151
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:This review presents an overview of the published literature on the effectiveness of continuing professional education (CPE), which includes continuing medical education (CME) of different health care professionals in healthcare settings, for improving patient management and patient outcomes. This review sum...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610209008746
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:The high prevalence of mild cognitive impairment (MCI) in Hong Kong, as previously reported, requires verification. Furthermore, the relationship between loneliness, depression, and cognitive impairment with regards to MCI are unclear. The present study aims to establish the prevalence of MCI in a community ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610216000430
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Elderly suicide rates are associated with the elderly population size, the proportion of elderly in the general population and the elderly dependency ratio. METHODS:A cross-national study examining the "a priori" hypothesis that the relationship between elderly suicide rates and average annual population gr...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208007953
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Whereas the State-Trait Anxiety Inventory (STAI-Y) is probably the most widely used self-reported measure of anxiety, the lack of current norms among elderly people appears to be problematic in both a clinical and research context. The objective of the present study was to provide normative data for the STAI...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000300
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:Despite delirium being common in older hospitalized people, little is known about its management. The aims of this study are (1) to describe the pharmacological management of delirium in an acute care setting as a baseline measure prior to the implementation of newly developed Australian guidelines; and (2) t...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208008028
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate survival time and life-expectancy in people with young-onset dementia (YOD) and to examine the relationship with age, sex, dementia subtype and comorbidity. DESIGN, SETTING AND PARTICIPANTS:Survival was examined in 198 participants in the Needs in Young-onset Dementi...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610219000152
更新日期:2019-12-01 00:00:00
abstract::The reliability and validity of the Subjective Burden Scale (SBS) were investigated in 255 Japanese family caregivers of elderly relatives with dementia. Values of the Cronbach's alpha reliability, split-half reliability (r), and test-retest reliability (r) were .87, .80, and .72, respectively. The SBS score was signi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610299005712
更新日期:1999-06-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2014-08-13 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610218000832
更新日期:2019-02-01 00:00:00