A five-year community-based longitudinal survival study of dementia in Beijing, China: a 10/66 Dementia Research Group population-based study.

abstract：:The purpose of this study was to examine the relationship between age-associated changes in central serotonergic function and abnormalities associated with major depression. Under randomized double-blind conditions, prolactin and cortisol responses to the serotonin-releasing agent d,l-fenfluramine hydrochloride (60 mg...

journal_title：International psychogeriatrics

authors： Lerer B,Gillon D,Lichtenberg P,Gorfine M,Gelfin Y,Shapira B

更新日期：1996-04-01 00:00:00

abstract：:Older widowers have high rates of completed suicide but have rarely been the subject of systematic inquiry. We investigated the prevalence of depressive symptoms and major depressive episodes (MDEs) in recently widowed older men over the first 13 months after bereavement. We employed a matched-pair longitudinal design...

journal_title：International psychogeriatrics

authors： Byrne GJ,Raphael B

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Mild cognitive impairment (MCI) is proposed to describe the transitional stage between normal cognitive aging and dementia. It has had significant impact in the field of dementia research, but it remains controversial whether or not it should be used as a diagnostic category in clinical practice. METHODS:Se...

journal_title：International psychogeriatrics

authors： Moreira T,Hughes JC,Kirkwood T,May C,McKeith I,Bond J

更新日期：2008-08-01 00:00:00

abstract：:Backround: Night-time agitation is a frequent symptom of dementia. It often causes nursing home admission and has been linked to circadian rhythm disturbances. A positive influence of light interventions on night-time agitation was shown in several studies. The aim of our study was to investigate whether there is a lo...

journal_title：International psychogeriatrics

authors： Wahnschaffe A,Nowozin C,Rath A,Floessner T,Appelhoff S,Münch M,Kunz D

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Whether perceived changes in memory parallel changes in brain pathology is uncertain. Positron emission tomography (PET) scans using 2-(1-{6-[(2-[F-18]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile (FDDNP) can measure levels of amyloid plaques and tau neurofibrillary tangles in vivo. Here we ...

journal_title：International psychogeriatrics

authors： Merrill DA,Siddarth P,Saito NY,Ercoli LM,Burggren AC,Kepe V,Lavretsky H,Miller KJ,Kim J,Huang SC,Bookheimer SY,Barrio JR,Small GW

更新日期：2012-07-01 00:00:00

abstract：:ABSTRACT Background: Cognitive impairment is underrecognized and misdiagnosed among community-dwelling older adults. At present, there is no consensus about which cognitive screening tool represents the "gold standard." However, one tool that shows promise is the Brief Cognitive Assessment Tool (BCAT), which was origi...

journal_title：International psychogeriatrics

authors： MacDougall EE,Mansbach WE,Clark K,Mace RA

更新日期：2014-08-13 00:00:00

abstract：:ABSTRACT Background: The association between disability and depression is complex, with disability well established as a correlate and consequence of late life depression. Studies in community samples report that greater volumes of cerebral white matter hyperintensities (WMHs) seen on brain imaging are linked with fun...

journal_title：International psychogeriatrics

authors： Hybels CF,Pieper CF,Landerman LR,Payne ME,Steffens DC

更新日期：2014-05-09 00:00:00

abstract：BACKGROUND:Previous studies have shown that the presence of depressive symptoms among older persons was evidently associated with subsequent physical and functional decline. However, few studies have directly examined the impact of changes in depressive symptoms or depressed mood on changes in functional ability. The p...

journal_title：International psychogeriatrics

authors： Nyunt MS,Lim ML,Yap KB,Ng TP

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Socioeconomic status (SES) has been identified as a possible risk factor for the development of dementia, with low SES shown to be associated with a higher prevalence of dementia, increased psychiatric comorbidity and worse baseline cognitive functioning. Few studies have actually looked at the impact of SES...

journal_title：International psychogeriatrics

authors： Fischer C,Yeung E,Hansen T,Gibbons S,Fornazzari L,Ringer L,Schweizer TA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Older migrants with dementia and limited English language proficiency in residential care may have unmet needs for social interaction. This project compared verbal communication and prescribed psychiatric medication of Greek and Italian residents with dementia in ethno-specific and mainstream residential car...

journal_title：International psychogeriatrics

authors： Runci SJ,Eppingstall BJ,O'Connor DW

更新日期：2012-05-01 00:00:00

abstract：:ABSTRACTBackground:Dementia is a neurodegenerative syndrome that interferes with multiple aspects of life, including cognition, daily functioning, and behavior. Despite the large heterogeneity in symptom development, these three domains are seldom studied simultaneously. This study investigates how trajectories of the...

journal_title：International psychogeriatrics

authors： Haaksma ML,Leoutsakos JS,Bremer JAE,Aalten P,Ramakers IHGB,Verhey FRJ,Olde Rikkert MGM,Melis RJF

更新日期：2018-06-01 00:00:00

abstract：:ABSTRACTBackground:The aim of this study is to identify the prevalence and risk factors of documented delirium in general practices in Germany. METHODS:The present study includes 2,194 patients over the age of 65 years with delirium and 2,194 controls without delirium from a sample of 6,180,042 patients from 1,262 ge...

journal_title：International psychogeriatrics

authors： Bohlken J,Kostev K

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:There has been an increasing interest in the relationship between severity of disease and costs in the care of people with dementia. Much of the current evidence is based on cross-sectional data, suggesting the need to examine trends over time for this important and growing cohort of the population. METHODS...

journal_title：International psychogeriatrics

authors： Gillespie P,O'Shea E,Cullinan J,Buchanan J,Bobula J,Lacey L,Gallagher D,Mhaolain AN,Lawlor B,Enhancing Care in Alzheimer’s Disease (ECAD) Study Team.

更新日期：2015-05-01 00:00:00

abstract：:This article discusses the role of some pathogenetical factors in the main morphological variants of vascular dementia and their correlation with certain clinical parameters. On the basis of computer-tomographical (CT) studies of 62 patients with dementia, it was possible to distinguish three groups of patients, accor...

journal_title：International psychogeriatrics

authors： Kontsevoy VA,Medvedev AV,Vavilov SB,Shchirina MG

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Cognitive impairment places older adults at increased risk of functional decline, injuries, and hospitalization. Assessments to determine whether older persons are still capable of meeting the cognitive challenges of everyday living are crucial to ensure their safe and independent living in the community. Th...

journal_title：International psychogeriatrics

authors： Law LL,Barnett F,Gray MA,Yau MK,Siu AM

更新日期：2014-02-01 00:00:00

abstract：:ABSTRACTBackground:Delirium is a complex clinical syndrome characterized by disturbed consciousness, cognitive function, or perception and associated with serious adverse outcomes such as death, dementia, and the need for long-term care. However, recognition and management of delirium is poorly prioritized even though...

journal_title：International psychogeriatrics

authors： Oberai T,Killington M,Laver K,Crotty M,Jaarsma R

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:A third of family members caring for people with dementia report acting abusively towards them, but there are currently no evidence-based interventions to reduce or prevent such behavior. Family carers who act abusively have not previously been consulted about what may help to reduce abuse. METHOD:We prospe...

journal_title：International psychogeriatrics

authors： Selwood A,Cooper C,Owens C,Blanchard M,Livingston G

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The Addenbrooke's Cognitive Examination (ACE) and its Revised version (ACE-R) are relatively new screening tools for cognitive impairment that may improve upon the well-known Mini-Mental State Examination (MMSE) and other brief batteries. We systematically reviewed diagnostic accuracy studies of ACE and ACE-...

journal_title：International psychogeriatrics

authors： Larner AJ,Mitchell AJ

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Understanding the prevalence, incidence and cofactors of depression among long-term elderly nursing home (LTNH) residents domiciled for eight months or more may help optimize depression treatment in this vulnerable group. We quantified first year depression in American LTNH residents and the associations bet...

journal_title：International psychogeriatrics

authors： Hoover DR,Siegel M,Lucas J,Kalay E,Gaboda D,Devanand DP,Crystal S

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The Cambridge Cognitive Examination (CAMCOG) is a useful test in screening for Alzheimer's disease (AD). However, the interpretation of CAMCOG cut-off scores is problematic and reference values are needed for different educational strata. Given the importance of earlier diagnoses of mild dementia, new cut-of...

journal_title：International psychogeriatrics

authors： Aprahamian I,Martinelli JE,Cecato J,Izbicki R,Yassuda MS

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine levels, rates and progression of apathy in healthy older persons and to investigate factors associated with its progression. METHODS:Seventy-six healthy elderly subjects, aged 58-85 years (mean 69.9), who were recruited by general advertisement and through local commun...

journal_title：International psychogeriatrics

authors： Brodaty H,Altendorf A,Withall A,Sachdev P

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:Older people commonly present with memory loss although on assessment are not found to have a full dementia complex. Previous studies have suggested however that people with subjective and objective cognitive loss are at higher risk of dementia. We aimed to determine from the literature the rate of conversio...

journal_title：International psychogeriatrics

authors： Bruscoli M,Lovestone S

更新日期：2004-06-01 00:00:00

abstract：:Most people who work in aged care have a fair idea of what is meant by cognitive impairment or decline, and we have some moderately robust instruments for detecting it and measuring change over time. Frailty is much more difficult to define, but like hard core pornography (Stewart, 1964), many of us "know it when we s...

journal_title：International psychogeriatrics

authors： Ames D

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The elderly are at high risk of developing tuberculosis. The prevalence and incidence of depression and anxiety are higher in those with tuberculosis than in the general population. A positive correlation between national suicide rates and rates of mortality due to tuberculosis has been reported. METHODS:Th...

journal_title：International psychogeriatrics

authors： Shah A

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:We assessed the relationship between cognitive impairment (including mild cognitive impairment with no signs of dementia, and dementia) and risk for depression in old age (60 years and older). METHODS:MEDLINE, EMBASE and the Cochrane Library database were used to identify potential studies. All of the clini...

journal_title：International psychogeriatrics

authors： Huang CQ,Wang ZR,Li YH,Xie YZ,Liu QX

更新日期：2011-05-01 00:00:00

abstract：:ABSTRACTBackground:Evidence suggests that semantic interference may be a sensitive indicator of early dementia. We examined the utility of the Semantic Interference Test (SIT), a cognitive stress memory paradigm which taps proactive and retroactive semantic interference, for predicting progression from mild cognitive ...

journal_title：International psychogeriatrics

authors： Beer JC,Snitz BE,Chang CH,Loewenstein DA,Ganguli M

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:To examine the effects of complex cognitive (mahjong) and physical (Tai Chi) activities on dementia severity in nursing home residents with dementia. METHODS:Cluster-randomized open-label controlled design. 110 residents were randomized by nursing home into three conditions: mahjong, Tai Chi, and simple han...

journal_title：International psychogeriatrics

authors： Cheng ST,Chow PK,Song YQ,Yu EC,Lam JH

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The clinical presentations in dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) overlap considerably with that of Alzheimer's disease (AD) despite different pathological processes. Autopsy studies have also shown that multiple brain pathology occurs frequently, even in cases with a single cli...

journal_title：International psychogeriatrics

authors： Piguet O,Halliday GM,Creasey H,Broe GA,Kril JJ

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:This study was conducted to estimate prevalence rates and risk factors for late-life depression in a large nationwide representative sample from Taiwan. METHODS:A total of 5,664, randomly sampled individuals aged ≥55 years were enrolled. Clinically, relevant depressive symptoms were classified using the Cen...

journal_title：International psychogeriatrics

authors： Wu CS,Yu SH,Lee CY,Tseng HY,Chiu YF,Hsiung CA

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Despite the high prevalence and morbidity of minor and subsyndromal depression in primary care elderly people, there are few data to identify those at highest risk of poor outcomes. The goal of this observational cohort study was to characterize the one-year outcomes of minor and subsyndromal depression, exa...

journal_title：International psychogeriatrics

authors： Lyness JM,Chapman BP,McGriff J,Drayer R,Duberstein PR

更新日期：2009-02-01 00:00:00