Abstract:
BACKGROUND:The Cambridge Cognitive Examination (CAMCOG) is a useful test in screening for Alzheimer's disease (AD). However, the interpretation of CAMCOG cut-off scores is problematic and reference values are needed for different educational strata. Given the importance of earlier diagnoses of mild dementia, new cut-off values are required which take into account patients with low levels of education. This study aims to evaluate whether the CAMCOG can be used as an accurate screening test among AD patients and normal controls with different educational levels. METHODS:Cross-sectional assessment was undertaken of 113 AD and 208 elderly controls with heterogeneous educational levels (group 1: 1-4 years; group 2: 5-8 years; and group 3: ≥ 9 years) from a geriatric clinic. submitted to a thorough diagnostic evaluation for AD including the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX). Controls had no cognitive or mood complaints. Sensitivity (SE) and specificity (SP) for the CAMCOG in each educational group was assessed with receiver-operator-characteristic (ROC) curves. RESULTS:CAMCOG mean values were lower when education was reduced in both diagnostic groups (controls - group 1: 87; group 2: 91; group 3: 96; AD - group 1: 63; group 2: 62; group 3: 77). Cut-off scores for the three education groups were 79, 80 and 90, respectively. SE and SP varied among the groups (group 1: 88.1% and 83.5%; group 2: 84.6% and 96%; group 3: 70.8% and 90%). CONCLUSION:The CAMCOG can be used as a cognitive test for patients with low educational level with good accuracy. Patients with higher education showed lower scores than previously reported.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Aprahamian I,Martinelli JE,Cecato J,Izbicki R,Yassuda MSdoi
10.1017/S104161021000116Xsubject
Has Abstractpub_date
2011-02-01 00:00:00pages
96-101issue
1eissn
1041-6102issn
1741-203Xpii
S104161021000116Xjournal_volume
23pub_type
杂志文章abstract:BACKGROUND:Increasing out-of-pocket health expenditure among older people worsens the inequitable access to essential health services in low and middle-income countries (LMIC). We investigated various socioeconomic and health factors associated with out-of-pocket and catastrophic health expenditures among rural older p...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021200083X
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Multifactorial strategies that prevent or delay the onset or progress of cognitive decline and dementia are needed, and should include education regarding recognized risk factors. The current study sought to investigate whether older adults "at risk" of cognitive decline benefit from psychoeducation targetin...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210001109
更新日期:2011-04-01 00:00:00
abstract::ABSTRACTBackground:Dementia is a neurodegenerative syndrome that interferes with multiple aspects of life, including cognition, daily functioning, and behavior. Despite the large heterogeneity in symptom development, these three domains are seldom studied simultaneously. This study investigates how trajectories of the...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610217000321
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:This study aimed to assess the prevalence, incidence, and persistence of suicidal ideation (SI), and to investigate the psychosocial factors associated with these. METHODS:A total of 1,204 community dwelling elderly adults aged 65 years or older were evaluated at baseline, 909 (75%) of whom were followed tw...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001634
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Behavioral and psychological symptoms of dementia (BPSD) cause caregiver distress and earlier institutionalization. We compared the prevalence and characteristics of BPSD between institution residents and memory clinic outpatients with Alzheimer's disease (AD) to test the hypothesis that there is more BPSD a...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209990767
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:The purpose of the study was to examine the attention deficit hyperactivity disorder (ADHD) symptomatology across the lifespan by comparing older individuals' self-reports about current ADHD symptoms and symptoms in childhood. METHODS:The 25-item Wender Utah Rating Scale (WURS) was initially administered in...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002050
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:The field of geriatric medicine has identified a need for an evaluative tool that can rapidly quantify global cognitive ability and accurately monitor change over time in patients with a wide range of impairments. We hypothesized that the development of an adaptive test approach to cognitive measurement woul...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211000615
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Dementia caregiving has been linked to negative consequences for mental health in caregivers. Although depression seems to be an enduring psychological consequence associated with caregiving, little is known about the longitudinal effects that modulating variables related to coping strategies have on caregiv...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002237
更新日期:2012-08-01 00:00:00
abstract::Most people who work in aged care have a fair idea of what is meant by cognitive impairment or decline, and we have some moderately robust instruments for detecting it and measuring change over time. Frailty is much more difficult to define, but like hard core pornography (Stewart, 1964), many of us "know it when we s...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217000060
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:A single-item depression measure may not be adequate in capturing the complex entity of mental health, despite wide use of this indicator in community studies. This study evaluated the accuracy of a single-question depression measure in comparison to two composite indices-the Center for Epidemiologic Studies...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217001673
更新日期:2018-01-01 00:00:00
abstract::ABSTRACTBackground:Little is known about the combined use of benzodiazepines and antidepressants in older psychiatric patients. This study examined the prescription pattern of concurrent benzodiazepines in older adults treated with antidepressants in Asia, and explored its demographic and clinical correlates. METHODS...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610217002563
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:The aim of this study was to test the association between anxiety at the time of hospitalization and falls occurring within one month of discharge, and to offer potential mechanisms for this association. METHODS:One-month, prospective cohort study of 556 older adults in two medical centers in Israel. Anxiet...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215002306
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Cognitive assessment of older persons, particularly those with impairment, is hampered by measurement error and the ethical issues of testing people with dementia. A potential source of valuable information about end-of-life cognitive status can be gained from those who knew the respondent well - mostly rela...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210001201
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Aggressive behavior (AB) is common in institutional settings. It is an important issue because of its consequences on both the person manifesting such behaviors and their caregivers. Although there are numerous studies assessing non-pharmacologic strategies to manage AB in older adults, no extensive review o...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610205002929
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:The social and economic burden of Alzheimer's disease (AD) and its increasing prevalence has led to much work on new treatment strategies and clinical trials. The search for surrogate markers of disease progression continues but traditional parallel group trial designs that use well-established, but often in...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610211001116
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:The clinical presentations in dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) overlap considerably with that of Alzheimer's disease (AD) despite different pathological processes. Autopsy studies have also shown that multiple brain pathology occurs frequently, even in cases with a single cli...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209009454
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Both anxiety disorders and subclinical anxiety symptoms are related to poorer health and functioning in later life. Because worry is an important component of anxiety, the accurate measurement of worry is crucial to studying the etiology, prevention and treatment of anxiety disorders. Assessment of the trait...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610206003450
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Frailty in older adults is a multifactorial syndrome defined by low metabolic reserve, less resistance to stressors, and difficulty in maintaining organic homeostasis due to cumulative decline of multiple physiological systems. The relationship between frailty and cognition remains unclear and studies about ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000907
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Cerebrovascular disease may cause "vascular depression" (VaD). Calcium channel-blockers are presumed treatments for cerebrovascular disease and might be expected to improve depression and prevent recurrence. OBJECTIVE:To examine the efficacy and tolerability of the use of nimodipine as an augmentation of fl...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1017/s1041610205001493
更新日期:2005-09-01 00:00:00
abstract::This community-based epidemiological survey concerns relationships between social and health factors and depression in a Finnish population aged 60 years or over. A multivariate analysis based on log-linear models is used in this study. The log-linear model showed five interactions for the depressed men and eight for ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s104161029300136x
更新日期:1993-04-01 00:00:00
abstract::Major advances in understanding the physiology and genetics of circadian rhythm in the past decade challenge the researcher of sleep/wake disorders in Alzheimer's disease (AD) to distinguish patient characteristics stable across the course of illness ("traits") from characteristics that vary with stage of illness ("st...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610202008293
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:Neuropsychiatric symptoms (NPS) are highly prevalent among nursing home patients with dementia. Several studies have investigated subsyndromes of NPS but the stability of these subsyndromes over time has rarely been examined. We have examined the stability over time of the factor structure of the Neuropsychi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021100086X
更新日期:2012-01-01 00:00:00
abstract::The dynamic processes and the way they interact in shaping a care system for demented patients are analyzed and discussed. The development of disability/dependency, interpreted in a simulation model based on Katz's index of ADL and Berger's scale "Rating the severity of senility," gave insight into the interplay of fo...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610296002888
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:There is currently a lack of consensus on the definition of successful aging (SA) and existing implementations have omitted constructs associated with SA. We used empirical methods to develop a dimensional model of SA that incorporates a wider range of associated variables, and we examined the relationship a...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002055
更新日期:2012-04-01 00:00:00
abstract::ABSTRACTBackground:This study investigates whether maintaining high levels of cognitive impairment and weak grip strength will predict a higher risk for mortality. METHODS:Data from the Korean Longitudinal Study of Aging (KLoSA) from 2006 to 2014 was assessed using longitudinal data analysis and included 5,812 resear...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218001175
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Cognitive impairment places older adults at increased risk of functional decline, injuries, and hospitalization. Assessments to determine whether older persons are still capable of meeting the cognitive challenges of everyday living are crucial to ensure their safe and independent living in the community. Th...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001889
更新日期:2014-02-01 00:00:00
abstract::ABSTRACTObjectives:Centenarians have survived into very late life, but whether they reach very old age in good health remains unclear. The purpose of this study was to compare the cardiovascular health status and cognitive functioning of centenarians in the United States with centenarians in Japan. DESIGN, SETTING, A...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218001813
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:The aim of this study is to investigate the diagnostic value of perfusion 99mTc-exametazime single photon emission computed tomography (SPECT) in the diagnosis of dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) in comparison with dopaminergic 123I-2beta-carbomethoxy-3beta-(4-iodophenyl)-n-(3-flu...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208007709
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:People with Young Onset Dementia (YOD) have specific needs for care. These people eventually require institutional care, usually delivered by institutions designed for the elderly. The Dutch network of care organizations delivering specialized YOD care offers a unique opportunity to obtain more knowledge of ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214001859
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Subjective memory complaints (SMCs) are a common occurrence for adults, which increase with age, and cause considerable distress. Traditionally SMCs have been assessed by either questionnaires, which ask whether a person has experienced given examples of SMCs, or open-ended questions which elicit spontaneous...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214001161
更新日期:2015-01-01 00:00:00