Abstract:
:Major advances in understanding the physiology and genetics of circadian rhythm in the past decade challenge the researcher of sleep/wake disorders in Alzheimer's disease (AD) to distinguish patient characteristics stable across the course of illness ("traits") from characteristics that vary with stage of illness ("states"). A components-of-variance approach with a repeated measures model was used to examine the between-subjects variance over time ("trait") vs. within-subjects ("state") variance in 42 patients with probable AD followed, on average, over 2 years on actigraphic sleep/wake measures. Mental status scores indexed stage of illness. Actigraphic measures of sleep efficiency and circadian rhythmicity appeared predominantly "trait," with between-individual differences accounting for over 55% of variance compared to the less than 5% of variance related to stage of cognitive impairment. We discuss how "state-trait" analyses can be helpful in identifying areas of assessment most likely to be fruitful objectives of physiologic and genetic research on sleep/wake disturbance in AD.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Yesavage JA,Taylor JL,Kraemer H,Noda A,Friedman L,Tinklenberg JRdoi
10.1017/s1041610202008293keywords:
subject
Has Abstractpub_date
2002-03-01 00:00:00pages
73-81issue
1eissn
1041-6102issn
1741-203Xjournal_volume
14pub_type
杂志文章abstract:BACKGROUND:Family involvement in long-term care (LTC) is important but it can prove challenging and result in conflict with staff if families do not feel connected to the LTC facility or if they believe that their contributions are undervalued. According to McMillan & Chavis (1986), sense of community (SOC) refers to a...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212001524
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To validate a shorter version of the Geriatric Depression Scale (GDS) for older, visually impaired patients. PARTICIPANTS:Subjects were 70 visually impaired adults over age 65 who were presenting for services at a low vision clinic. METHOD:Subjects were interviewed by a geriatric nurse practitioner. A struc...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610200006554
更新日期:2000-12-01 00:00:00
abstract::Over the past five to ten years, neuroimaging capability for neurodegenerative diseases has made remarkable progress. However, debate remains as to the true clinical utility of these advanced and costly investigations. Not only is the place of these tests in diagnostic algorithms unclear, but the access to them varies...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610211000901
更新日期:2011-09-01 00:00:00
abstract::Current approaches to the diagnosis of delirium are based upon the recognition of symptoms that emerge in the pathological state. As an alternative, we propose an approach to case identification for research purposes based on the recognition of significant changes in the cognitive or cerebral state of the individual p...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s104161029100073x
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Older people have a higher risk of drug-related problems (DRPs). However, little is known about the prevalence of DRPs in community-dwelling people who screened positive for dementia. Our study aimed to determine (1) the prevalence and types of DRPs and (2) the socio-demographic and clinical variables associ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217001442
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:In a previous paper, we presented results from a 12-week study of a Psychomotor DANCe Therapy INtervention (DANCIN) based on Danzón Latin Ballroom that involves motor, emotional-affective, and cognitive domains, using a multiple-baseline single-case design in three care homes. This paper reports the results ...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S104161021600171X
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:It is necessary to continue to explore the psychometric characteristics of key cognitive screening tests such as the Montreal Cognitive Assessment (MoCA) to diagnose cognitive decline as early as possible and to attend to the growing need of clinical trials involving mild cognitive impairment (MCI) participa...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215001982
更新日期:2016-05-01 00:00:00
abstract::The role of the physician is critical in the evaluation of cognitively impaired patients for two reasons: (a) The longitudinal relationship between the patient and physician provides a unique opportunity to observe changes over time, generating confidence that may encourage the patient and family to report any concern...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610297004729
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Community care workers' experience of delivering support to people with dementia is less researched than that of residential workers. The purpose of the study is to explore community-based dementia care workers' perspectives about their roles and the contextual variables that impact upon their work experienc...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002323
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Dementia caregiving has been linked to negative consequences for mental health in caregivers. Although depression seems to be an enduring psychological consequence associated with caregiving, little is known about the longitudinal effects that modulating variables related to coping strategies have on caregiv...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002237
更新日期:2012-08-01 00:00:00
abstract::ABSTRACTBackground:Dementia screening is a public health priority in Taiwan, where the prevalence of dementia is increasing because of an aging population. However, the reasons affect community-dwelling people to accept a referral to memory specialist clinic after dementia screening was still unclear. To investigate t...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002733
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:We examine the association between leisure-time activities and the risk of developing cognitive impairment among Chinese older people, and further investigate whether the association varies by educational level. METHODS:This follow-up study included 6,586 participants (aged 79.5 ± 9.8 years, range 65-105 ye...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610216001769
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Suicide is a major public health concern. The elderly have the highest rate of suicide and they make more lethal suicide attempts and have fewer psychiatric interventions than young people. Furthermore, they have old-age specific psychosocial difficulties. The present study investigated psychosocial risk fac...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211000263
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Older Puerto Rican adults have particularly high risk of diabetes compared to the general US population. Diabetes is associated with both higher depressive symptoms and cognitive decline, but less is known about the longitudinal relationship between cognitive decline and incident depressive symptoms in those...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217000746
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The elderly are at high risk of developing tuberculosis. The prevalence and incidence of depression and anxiety are higher in those with tuberculosis than in the general population. A positive correlation between national suicide rates and rates of mortality due to tuberculosis has been reported. METHODS:Th...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209990378
更新日期:2009-12-01 00:00:00
abstract::Positive psychiatry is the science and practice of psychiatry that focuses on psycho-bio-social study and promotion of well-being and health through enhancement of positive psychosocial factors (such as resilience, optimism, wisdom, and social support) in people with illnesses or disabilities as well as the in communi...
journal_title:International psychogeriatrics
pub_type: 社论
doi:10.1017/S1041610218002211
更新日期:2018-12-01 00:00:00
abstract::ABSTRACTBackground:The number of elderly individuals living in China is increasing rapidly. The aim of this study was to examine the potential risk factors of geriatric depression in rural areas. METHODS:A repeated cross-sectional study was conducted between January 2015 and October 2016 in rural China. Nine hundred ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000030
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Differentiating Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), two of the commonest forms of dementia in older age, remains a diagnostic challenge. To assist with better understanding of the differences between the conditions during life, we assessed limbic and subcortical brain volumes in AD,...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215001805
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:A carer-held record (CHR) was developed to enable carers to contribute to care plans for their relatives with dementia, alongside other professionals. The aim of this study was to establish whether CHRs provide any measurable benefits for carers, in the areas of health, stress, knowledge of dementia and locu...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610205002565
更新日期:2006-06-01 00:00:00
abstract::Understanding of vascular substrates of cognitive decline in the elderly is evolving to include a major emphasis on the impact of small vessel disease (SVD). While existing concepts of multi-infarct dementia and strategic infarct dementia remain valid, they present difficulty in generalizing clinicopathological correl...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610203008998
更新日期:2003-01-01 00:00:00
abstract::ABSTRACTBackground:Psychological and social resources such as extraversion, optimism, social support, or social networks contribute to adaptation and to successful aging. Building on assumptions derived from successful aging and from the developmental adaptation models, this study aims to analyze the joint impact of d...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000388
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:The IPA Taskforce on Mental Health Issues in Long-Term Care Homes seeks to improve mental health care in long-term care (LTC) homes. The aim of this paper is to provide recommendations on comprehensive assessment of depression and behavioral problems in order to further stimulate countries and professionals ...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610210000736
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:Nearly half of care home residents with advanced dementia have clinically significant agitation. Little is known about costs associated with these symptoms toward the end of life. We calculated monetary costs associated with agitation from UK National Health Service, personal social services, and societal per...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219002059
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:This study determined the reliability, validity, and factor structure of self-report emotions in persons with mild Alzheimer's disease (AD) and mild cognitive impairment (MCI) relative to controls. METHODS:Participants (mild AD, n = 73; MCI, n = 159; controls, n = 96) rated current emotions with the Visual ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021100041X
更新日期:2011-08-01 00:00:00
abstract::ABSTRACTBackground:Getting lost is a recognized complication in patients with dementia. Preventive measures are lacking. This study aims to investigate the effectiveness of a home-based missing incident prevention program (HMIPP) in reducing missing incidents, time of searching, and caregivers' stress. METHODS:The de...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000546
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:To explore the extent to which staff members in long-term care facilities (LTCF) have experienced situations of sexual harassment, how they commonly and ideally manage the situation, and how their work position influences their responses. DESIGN:Cross-sectional quantitative study, using the vignette techniq...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219001431
更新日期:2020-03-01 00:00:00
abstract::This article reviews the evidence available from natural history studies and randomized clinical trials (RCT) concerning what is now coined as amnestic MCI and vascular MCI and will answer the question about the similarity and difference of their progression toward dementia. The issues to be resolved prior to the use ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610203009293
更新日期:2003-01-01 00:00:00
abstract::Backround: Night-time agitation is a frequent symptom of dementia. It often causes nursing home admission and has been linked to circadian rhythm disturbances. A positive influence of light interventions on night-time agitation was shown in several studies. The aim of our study was to investigate whether there is a lo...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217001235
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Recognizing and diagnosing early onset dementia (EOD) can be complex and often takes longer than for late onset dementia. The objectives of this study are to investigate the barriers to diagnosis and to develop a typology of the diagnosis pathway for EOD caregivers. METHODS:Semi-structured interviews with 9...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211001013
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:In old age, both apathy and depression have been associated with an increased cardiovascular disease (CVD) risk. This study evaluated the mediating role of cardiovascular risk factors in the relationship of apathy and mood symptoms with incident CVD. METHODS:Prospective cohort study of 1,790 community-dwell...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215001751
更新日期:2016-04-01 00:00:00