Abstract:
BACKGROUND:Older people have a higher risk of drug-related problems (DRPs). However, little is known about the prevalence of DRPs in community-dwelling people who screened positive for dementia. Our study aimed to determine (1) the prevalence and types of DRPs and (2) the socio-demographic and clinical variables associated with DRPs in people screened positive for dementia in primary care. METHODS:The Dementia: life- and person-centered help in Mecklenburg-Western Pomerania (DelpHi-MV) study is a general practitioner (GP)-based cluster-randomized controlled intervention study to implement and evaluate an innovative concept of collaborative dementia care management in the primary care setting in Germany. Medication reviews of 446 study participants were conducted by pharmacists based on a comprehensive baseline assessment that included a computer-based home medication assessment. ClinicalTrials.gov Identifier: NCT01401582. RESULTS:A total of 1,077 DRPs were documented. In 414 study participants (93%), at least one DRP was detected by a pharmacist. The most frequent DRPs were administration and compliance problems (60%), drug interactions (17%), and problems with inappropriate drug choice (15%). The number of DRPs was significantly associated with the total number of drugs taken and with a formal diagnosis of a mental or behavioral disorder. CONCLUSIONS:Degree of cognitive impairment (MMSE defined) and formal diagnosis of dementia were not risk factors for an increased number of DRPs. However, the total number of drug taken and the presence of a diagnosis of mental and behavioral disorders were associated with an increased total number of DRPs.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Wucherer D,Thyrian JR,Eichler T,Hertel J,Kilimann I,Richter S,Michalowsky B,Zwingmann I,Dreier-Wolfgramm A,Ritter CA,Teipel S,Hoffmann Wdoi
10.1017/S1041610217001442subject
Has Abstractpub_date
2017-11-01 00:00:00pages
1857-1868issue
11eissn
1041-6102issn
1741-203Xpii
S1041610217001442journal_volume
29pub_type
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journal_title:International psychogeriatrics
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更新日期:2009-04-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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更新日期:2009-06-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
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journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1992-07-01 00:00:00
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更新日期:2009-02-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1992-01-01 00:00:00
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